FI935830A - Bisyklisiä amiinijohdannaisia - Google Patents
Bisyklisiä amiinijohdannaisia Download PDFInfo
- Publication number
- FI935830A FI935830A FI935830A FI935830A FI935830A FI 935830 A FI935830 A FI 935830A FI 935830 A FI935830 A FI 935830A FI 935830 A FI935830 A FI 935830A FI 935830 A FI935830 A FI 935830A
- Authority
- FI
- Finland
- Prior art keywords
- substituent
- atom
- amine derivatives
- bicyclic amine
- hydrogen atom
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP34603092 | 1992-12-25 | ||
JP34603092 | 1992-12-25 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI935830A0 FI935830A0 (fi) | 1993-12-23 |
FI935830A true FI935830A (fi) | 1994-06-26 |
FI105031B FI105031B (fi) | 2000-05-31 |
Family
ID=18380663
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI935830A FI105031B (fi) | 1992-12-25 | 1993-12-23 | Menetelmä uusien terapeuttisesti käyttökelpoisten 1-fluorisyklopropyyli-6-fluori-1,4-dihydro-4-oksokinoliini-3-karboksyylihappojohdannaisten valmistamiseksi |
Country Status (17)
Country | Link |
---|---|
US (1) | US5654318A (fi) |
EP (1) | EP0603887B1 (fi) |
JP (1) | JP3268098B2 (fi) |
KR (1) | KR100295483B1 (fi) |
CN (1) | CN1037441C (fi) |
AT (1) | ATE251157T1 (fi) |
AU (1) | AU669948B2 (fi) |
CA (1) | CA2112165C (fi) |
DE (1) | DE69333223T2 (fi) |
DK (1) | DK0603887T3 (fi) |
ES (1) | ES2208636T3 (fi) |
FI (1) | FI105031B (fi) |
NO (1) | NO301165B1 (fi) |
PH (1) | PH31587A (fi) |
PT (1) | PT603887E (fi) |
RU (1) | RU2125046C1 (fi) |
TW (1) | TW264476B (fi) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR0148277B1 (ko) * | 1993-01-18 | 1998-11-02 | 채영복 | 신규한 플루오르퀴놀론계 유도체 및 그의 제조방법 |
KR960004339A (ko) * | 1994-07-02 | 1996-02-23 | 임성기 | 신규한 퀴놀린계 화합물 및 그 의 제조방법 |
WO1996011194A1 (fr) * | 1994-10-06 | 1996-04-18 | Dainippon Pharmaceutical Co., Ltd. | Derive d'acide pyridonecarboxylique et intermediaire servant a effectuer sa synthese |
DE19546249A1 (de) * | 1995-12-12 | 1997-06-19 | Bayer Ag | Neue Kristallmodifikation des 1-Cyclopropyl-7-([S,S]-2,8-diazabicyclo[4,3,0]non-8-yl)-6-fluor-1,4-dihydro-8-methoxy-4-oxo-3-chinolincarbonsäure Hydrochlorid (CDCH), Verfahren zu dessen Herstellung und diese enthaltende pharmazeutische Zubereitungen |
NZ331468A (en) * | 1996-02-23 | 2000-02-28 | Bayer Ag | Substituted 8-cyano-1-cyclopropyl-7-(2,8-diazabicyclo-[4,3.0]-nonan-8-yl)-6-fluoro-1, 4-dihydro-4-oxo-3-quinolin carboxylic acids and their derivatives |
CA2247018A1 (en) * | 1996-02-27 | 1997-09-04 | Dainippon Pharmaceutical Co., Ltd. | Pyridonecarboxylic acid derivatives and intermediates for the synthesis thereof |
KR100531967B1 (ko) * | 1996-10-25 | 2005-11-30 | 다이이찌 세이야꾸 가부시기가이샤 | 트리사이클릭 아민 유도체, 이를 포함하는 항균제 및 퀴놀론 화합물의 제조방법 |
DE19652239A1 (de) * | 1996-12-16 | 1998-06-18 | Bayer Ag | Verwendung von 7-(2-Oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-chinolon- und -naphthyridoncarbonsäure-Derivaten zur Therapie von Helicobacter-pylori-Infektionen und den damit assoziierten gastroduodenalen Erkrankungen |
DE19821039A1 (de) * | 1998-05-11 | 1999-11-18 | Bayer Ag | Verfahren zur Herstellung von (S,S)-Benzyl-2,8-diazabicyclo[4.3.0]nonan |
DE19931115A1 (de) * | 1999-07-06 | 2001-01-11 | Bayer Ag | Racemisierung von R, S-Dioxo-Benzylpyrrolopiperidin |
CN1312131C (zh) * | 2000-02-09 | 2007-04-25 | 第一制药株式会社 | 包含作为活性成分的吡啶酮羧酸的抗耐酸细菌药 |
US6809105B2 (en) | 2000-04-27 | 2004-10-26 | Abbott Laboratories | Diazabicyclic central nervous system active agents |
MY145722A (en) | 2000-04-27 | 2012-03-30 | Abbott Lab | Diazabicyclic central nervous system active agents |
DE10022369A1 (de) | 2000-05-08 | 2001-11-15 | Bayer Ag | Verfahren zur Herstellung von Piperidinen |
ATE540950T1 (de) * | 2005-05-25 | 2012-01-15 | Merck Sharp & Dohme | Aminocyclohexane als dipeptidylpeptidase-iv- hemmer zur behandlung bzw. prävention von diabetes |
CN102101861B (zh) * | 2008-07-01 | 2012-07-18 | 韶远化学科技(上海)有限公司 | 含氮双杂环医药中间体的合成及工艺方法 |
CA2762022A1 (en) | 2009-05-15 | 2010-11-18 | Redx Pharma Limited | Redox drug derivatives |
CN102675308A (zh) * | 2011-03-17 | 2012-09-19 | 苏州中科天马肽工程中心有限公司 | 一种制备8-苄基-2,8-二氮杂二环[4.3.0]壬烷的方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ210805A (en) * | 1984-01-19 | 1988-04-29 | Norton Co | Aluminous abrasive grits or shaped bodies |
JPS6212760A (ja) * | 1984-12-14 | 1987-01-21 | Dai Ichi Seiyaku Co Ltd | 1−(2−ハロゲノシクロプロピル)キノリンカルボン酸誘導体 |
DE3509546A1 (de) * | 1985-03-16 | 1986-09-25 | Bayer Ag, 5090 Leverkusen | 7-amino-1-(subst.cyclopropyl)-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
MY105136A (en) * | 1988-04-27 | 1994-08-30 | Daiichi Seiyaku Co | Optically active pyridonecarboxylic acid derivatives. |
DE3906365A1 (de) * | 1988-07-15 | 1990-01-18 | Bayer Ag | 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe |
DE3910663A1 (de) * | 1989-04-03 | 1990-10-04 | Bayer Ag | 5-alkylchinoloncarbonsaeuren |
KR910009330B1 (ko) * | 1989-10-23 | 1991-11-11 | 재단법인 한국화학연구소 | 항균작용을 갖는 퀴놀린계 화합물과 그의 제조방법 |
CA2030217A1 (en) * | 1989-11-21 | 1991-05-22 | Jun Imose | Pyridone-carboxylic acid derivatives useful as veterinary medicines |
JPH03188080A (ja) * | 1989-12-15 | 1991-08-16 | Banyu Pharmaceut Co Ltd | ピリドンカルボン酸誘導体 |
DE4032560A1 (de) * | 1990-10-13 | 1992-04-16 | Bayer Ag | 7-(2,7-diazabicyclo(3.3.0)octyl)-3-chinolon- und -naphtyridoncarbonsaeure-derivate |
WO1992021659A1 (en) * | 1991-05-28 | 1992-12-10 | Daiichi Pharmaceutical Co., Ltd. | Pyridonecarboxylic acid derivative |
TW209865B (fi) * | 1992-01-10 | 1993-07-21 | Bayer Ag | |
DE4230804A1 (de) * | 1992-09-15 | 1994-03-17 | Bayer Ag | 7-Isoindolinyl-chinolon- und -naphthyridon-Derivate |
-
1993
- 1993-12-22 CA CA002112165A patent/CA2112165C/en not_active Expired - Fee Related
- 1993-12-22 JP JP32301193A patent/JP3268098B2/ja not_active Expired - Fee Related
- 1993-12-22 NO NO934753A patent/NO301165B1/no not_active IP Right Cessation
- 1993-12-23 EP EP93120802A patent/EP0603887B1/en not_active Expired - Lifetime
- 1993-12-23 AT AT93120802T patent/ATE251157T1/de not_active IP Right Cessation
- 1993-12-23 DE DE69333223T patent/DE69333223T2/de not_active Expired - Fee Related
- 1993-12-23 DK DK93120802T patent/DK0603887T3/da active
- 1993-12-23 RU RU93056853A patent/RU2125046C1/ru not_active IP Right Cessation
- 1993-12-23 FI FI935830A patent/FI105031B/fi not_active IP Right Cessation
- 1993-12-23 PT PT93120802T patent/PT603887E/pt unknown
- 1993-12-23 TW TW082110919A patent/TW264476B/zh active
- 1993-12-23 US US08/172,233 patent/US5654318A/en not_active Expired - Lifetime
- 1993-12-23 AU AU52695/93A patent/AU669948B2/en not_active Ceased
- 1993-12-23 ES ES93120802T patent/ES2208636T3/es not_active Expired - Lifetime
- 1993-12-24 KR KR1019930029472A patent/KR100295483B1/ko not_active IP Right Cessation
- 1993-12-24 PH PH47546A patent/PH31587A/en unknown
- 1993-12-25 CN CN93121757A patent/CN1037441C/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
PT603887E (pt) | 2004-02-27 |
DE69333223T2 (de) | 2004-08-05 |
JPH06239857A (ja) | 1994-08-30 |
AU669948B2 (en) | 1996-06-27 |
NO301165B1 (no) | 1997-09-22 |
US5654318A (en) | 1997-08-05 |
EP0603887B1 (en) | 2003-10-01 |
CA2112165C (en) | 2003-04-08 |
AU5269593A (en) | 1994-07-07 |
PH31587A (en) | 1998-11-03 |
NO934753D0 (no) | 1993-12-22 |
RU2125046C1 (ru) | 1999-01-20 |
ATE251157T1 (de) | 2003-10-15 |
CN1037441C (zh) | 1998-02-18 |
KR940014397A (ko) | 1994-07-18 |
DE69333223D1 (de) | 2003-11-06 |
EP0603887A2 (en) | 1994-06-29 |
ES2208636T3 (es) | 2004-06-16 |
TW264476B (fi) | 1995-12-01 |
FI935830A0 (fi) | 1993-12-23 |
CN1095068A (zh) | 1994-11-16 |
DK0603887T3 (da) | 2004-01-26 |
FI105031B (fi) | 2000-05-31 |
CA2112165A1 (en) | 1994-06-26 |
NO934753L (no) | 1994-06-27 |
KR100295483B1 (ko) | 2001-09-17 |
EP0603887A3 (en) | 1995-04-26 |
JP3268098B2 (ja) | 2002-03-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MA | Patent expired |