FI932831A - ETF FOERFARANDE FOER FRAMSTAELLNING AV EN SYNTETISK LEDARSEKVENS - Google Patents

ETF FOERFARANDE FOER FRAMSTAELLNING AV EN SYNTETISK LEDARSEKVENS Download PDF

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Publication number
FI932831A
FI932831A FI932831A FI932831A FI932831A FI 932831 A FI932831 A FI 932831A FI 932831 A FI932831 A FI 932831A FI 932831 A FI932831 A FI 932831A FI 932831 A FI932831 A FI 932831A
Authority
FI
Finland
Prior art keywords
syntetisk
ledarsekvens
etf
foerfarande foer
foer framstaellning
Prior art date
Application number
FI932831A
Other languages
Finnish (fi)
Other versions
FI932831A0 (en
Inventor
Lars Christiansen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of FI932831A publication Critical patent/FI932831A/en
Publication of FI932831A0 publication Critical patent/FI932831A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Consolidation Of Soil By Introduction Of Solidifying Substances Into Soil (AREA)
FI932831A 1990-12-19 1993-06-18 For the purposes of this Regulation, the following guidelines may be used FI932831A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK300090A DK300090D0 (en) 1990-12-19 1990-12-19 PROCEDURE FOR PREPARING LEADER SEQUENCES
PCT/DK1991/000396 WO1992011378A1 (en) 1990-12-19 1991-12-18 A method of constructing synthetic leader sequences

Publications (2)

Publication Number Publication Date
FI932831A true FI932831A (en) 1993-06-18
FI932831A0 FI932831A0 (en) 1993-06-18

Family

ID=8118017

Family Applications (1)

Application Number Title Priority Date Filing Date
FI932831A FI932831A0 (en) 1990-12-19 1993-06-18 For the purposes of this Regulation, the following guidelines may be used

Country Status (17)

Country Link
EP (1) EP0563175A1 (en)
JP (1) JPH06503957A (en)
KR (1) KR930703450A (en)
AU (1) AU660161B2 (en)
CA (1) CA2098731A1 (en)
CZ (1) CZ119293A3 (en)
DK (1) DK300090D0 (en)
FI (1) FI932831A0 (en)
HU (1) HUT68751A (en)
IE (1) IE914433A1 (en)
IL (1) IL100408A0 (en)
MX (1) MX9102684A (en)
NZ (1) NZ241011A (en)
PT (1) PT99848A (en)
SK (1) SK62593A3 (en)
WO (1) WO1992011378A1 (en)
ZA (1) ZA919932B (en)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI92601C (en) * 1992-03-11 1994-12-12 Marja Makarow Procedure for secretion of yeast beneficial proteins
US5538863A (en) * 1993-07-01 1996-07-23 Immunex Corporation Expression system comprising mutant yeast strain and expression vector encoding synthetic signal peptide
US5639642A (en) * 1994-06-16 1997-06-17 Novo Nordisk A/S Synthetic leader peptide sequences
ZA954983B (en) * 1994-06-17 1996-02-14 Novo Nordisk As N-terminally extended proteins expressed in yeast
US6500645B1 (en) 1994-06-17 2002-12-31 Novo Nordisk A/S N-terminally extended proteins expressed in yeast
HRP940432B1 (en) * 1994-08-05 2003-10-31 Pliva Pharm & Chem Works Dna sequences encoding biosynthetic insulin precursors and process for preparation of insulin
CN101955921A (en) 1995-03-17 2011-01-26 诺沃奇梅兹有限公司 Novel endoglucanases
DE69738695D1 (en) 1996-03-01 2008-06-26 Novo Nordisk As Anti-appetite peptide, its compositions and use
US6017731A (en) 1996-12-13 2000-01-25 Chiron Corporation Method for expression of heterologous proteins in yeast
EP1049790A1 (en) 1998-01-23 2000-11-08 Novo Nordisk A/S Process for making desired polypeptides in yeast
ATE474930T1 (en) 1999-12-29 2010-08-15 Novo Nordisk As METHOD FOR PRODUCING INSULIN PRECURSORS AND ANALOGUES OF INSULIN PRECURSORS WITH IMPROVED FERMENTATION YIELD IN YEAST
AT410217B (en) * 2000-06-15 2003-03-25 Cistem Biotechnologies Gmbh VECTOR AND A METHOD FOR THE EXPRESSION AND SELECTION OF RANDOMIZED PEPTIDE SEQUENCES
CA2441580A1 (en) 2001-03-22 2002-10-03 Novo Nordisk Health Care Ag Coagulation factor vii derivatives
ES2376694T3 (en) 2001-09-27 2012-03-16 Novo Nordisk Health Care Ag HUMAN COAGULATION FACTOR VII POLIPED PEPDES VII.
ES2381110T3 (en) 2003-09-09 2012-05-23 Novo Nordisk Health Care Ag Coagulation Factor VII Polypeptides
WO2005047508A1 (en) 2003-11-14 2005-05-26 Novo Nordisk A/S Processes for making acylated insulin
JP5697831B2 (en) 2003-12-03 2015-04-08 ノヴォ ノルディスク アー／エス Single chain insulin
WO2005078116A1 (en) * 2004-01-16 2005-08-25 Qiuyun Liu A method of isolating antibacterial peptides and the isolated peptides thereof
RU2412199C2 (en) 2005-04-18 2011-02-20 Ново Нордиск А/С Versions of il-21
EP1917363B1 (en) 2005-08-16 2011-06-22 Novo Nordisk A/S Method for making mature insulin polypeptides
WO2007031559A2 (en) 2005-09-14 2007-03-22 Novo Nordisk Health Care Ag Human coagulation factor vii polypeptides
ES2387955T3 (en) 2006-02-27 2012-10-04 Novo Nordisk A/S Insulin derivatives
EP2069502B1 (en) 2006-09-27 2014-02-26 Novo Nordisk A/S Method for making maturated insulin polypeptides
US8575096B2 (en) 2007-08-13 2013-11-05 Novo Nordisk A/S Rapid acting insulin analogues
KR20100053561A (en) 2007-08-15 2010-05-20 노보 노르디스크 에이/에스 Insulin analogues with an acyl and alkylene glycol moiety
US8962794B2 (en) 2007-08-15 2015-02-24 Novo Nordisk A/S Insulins with an acyl moiety comprising repeating units of alkylene glycol containing amino acids
WO2011089170A2 (en) 2010-01-22 2011-07-28 Novo Nordisk A/S Process for preparing fgf-21 with low degree of o-glycosylation
WO2010103038A1 (en) 2009-03-11 2010-09-16 Novo Nordisk A/S Interleukin-21 variants having antagonistic binding to the il-21 receptor
AU2010272483B2 (en) 2009-07-17 2016-07-21 Omeros Corporation MASP isoforms as inhibitors of complement activation
US8815541B2 (en) 2009-11-25 2014-08-26 Novo Nordisk A/S Method for making polypeptides
US9096843B2 (en) 2009-12-01 2015-08-04 Novo Nordisk A/S Peptidyl α-hydroxyglycine α-amidating lyases
AU2011222883B2 (en) 2010-03-05 2016-05-26 Omeros Corporation Chimeric inhibitor molecules of complement activation
WO2012015692A2 (en) * 2010-07-28 2012-02-02 Smartcells, Inc. Recombinantly expressed insulin polypeptides and uses thereof
CN104136041B (en) 2012-02-09 2021-06-29 Var2制药有限公司 Targeted chondroitin sulfate glycans
US20150307865A1 (en) 2012-10-15 2015-10-29 Novo Nordisk Health Care Ag Coagulation factor vii polypeptides
US20160115216A1 (en) 2013-06-07 2016-04-28 Novo Nordisk A/S Method for Making Mature Insulin Polypeptides
JP6275847B2 (en) * 2014-02-28 2018-02-07 ノヴォ ノルディスク アー／エス Alpha mating factor propeptide variant
CN112789504A (en) 2018-07-13 2021-05-11 瓦克特诊断有限责任公司 Isolation of fetal-derived circulating cells using the recombinant malaria protein VAR2CSA

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK463887D0 (en) * 1987-09-07 1987-09-07 Novo Industri As GAERLEADER
CA1340772C (en) * 1987-12-30 1999-09-28 Patricia Tekamp-Olson Expression and secretion of heterologous protiens in yeast employing truncated alpha-factor leader sequences
AU633020B2 (en) * 1988-07-23 1993-01-21 Novozymes Delta Limited New secretory leader sequences
DK105489D0 (en) * 1989-03-03 1989-03-03 Novo Nordisk As POLYPEPTIDE

Also Published As

Publication number Publication date
ZA919932B (en) 1992-08-26
HUT68751A (en) 1995-07-28
CZ119293A3 (en) 1994-02-16
WO1992011378A1 (en) 1992-07-09
EP0563175A1 (en) 1993-10-06
SK62593A3 (en) 1993-10-06
PT99848A (en) 1993-06-30
AU9134891A (en) 1992-07-22
IL100408A0 (en) 1992-09-06
HU9301801D0 (en) 1993-10-28
FI932831A0 (en) 1993-06-18
JPH06503957A (en) 1994-05-12
MX9102684A (en) 1992-06-01
CA2098731A1 (en) 1992-06-19
KR930703450A (en) 1993-11-30
IE914433A1 (en) 1992-07-01
AU660161B2 (en) 1995-06-15
DK300090D0 (en) 1990-12-19
NZ241011A (en) 1993-04-28

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