DK300090D0 - PROCEDURE FOR PREPARING LEADER SEQUENCES - Google Patents

PROCEDURE FOR PREPARING LEADER SEQUENCES

Info

Publication number
DK300090D0
DK300090D0 DK300090A DK300090A DK300090D0 DK 300090 D0 DK300090 D0 DK 300090D0 DK 300090 A DK300090 A DK 300090A DK 300090 A DK300090 A DK 300090A DK 300090 D0 DK300090 D0 DK 300090D0
Authority
DK
Denmark
Prior art keywords
preparing
procedure
leader sequences
leader
sequences
Prior art date
Application number
DK300090A
Other languages
Danish (da)
Inventor
Lars Christiansen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Priority to DK300090A priority Critical patent/DK300090D0/en
Publication of DK300090D0 publication Critical patent/DK300090D0/en
Priority to NZ241011A priority patent/NZ241011A/en
Priority to AU91348/91A priority patent/AU660161B2/en
Priority to EP92901668A priority patent/EP0563175A1/en
Priority to JP4502056A priority patent/JPH06503957A/en
Priority to IL100408A priority patent/IL100408A0/en
Priority to HU9301801A priority patent/HUT68751A/en
Priority to PCT/DK1991/000396 priority patent/WO1992011378A1/en
Priority to PT99848A priority patent/PT99848A/en
Priority to CA002098731A priority patent/CA2098731A1/en
Priority to CS931192A priority patent/CZ119293A3/en
Priority to IE443391A priority patent/IE914433A1/en
Priority to ZA919932A priority patent/ZA919932B/en
Priority to KR1019930701890A priority patent/KR930703450A/en
Priority to SK62593A priority patent/SK62593A3/en
Priority to MX9102684A priority patent/MX9102684A/en
Priority to NO93932235A priority patent/NO932235L/en
Priority to FI932831A priority patent/FI932831A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Consolidation Of Soil By Introduction Of Solidifying Substances Into Soil (AREA)
DK300090A 1990-12-19 1990-12-19 PROCEDURE FOR PREPARING LEADER SEQUENCES DK300090D0 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
DK300090A DK300090D0 (en) 1990-12-19 1990-12-19 PROCEDURE FOR PREPARING LEADER SEQUENCES
NZ241011A NZ241011A (en) 1990-12-19 1991-12-17 Leader sequence for secreting heterologous polypeptides in yeast, vectors using it, yeast cells and process for producing heterologous polypeptides
SK62593A SK62593A3 (en) 1990-12-19 1991-12-18 Method of constructing synthetic leader sequences
PT99848A PT99848A (en) 1990-12-19 1991-12-18 PROCESS FOR THE PREPARATION OF SYNTHETIC LEADER SEQUENCES
CA002098731A CA2098731A1 (en) 1990-12-19 1991-12-18 Method of constructing synthetic leader sequences
JP4502056A JPH06503957A (en) 1990-12-19 1991-12-18 How to construct a synthetic leader sequence
IL100408A IL100408A0 (en) 1990-12-19 1991-12-18 Construction of synthetic leader peptide sequences
HU9301801A HUT68751A (en) 1990-12-19 1991-12-18 A method of constructing synthetic leader sequences
PCT/DK1991/000396 WO1992011378A1 (en) 1990-12-19 1991-12-18 A method of constructing synthetic leader sequences
AU91348/91A AU660161B2 (en) 1990-12-19 1991-12-18 A method of constructing synthetic leader sequences
EP92901668A EP0563175A1 (en) 1990-12-19 1991-12-18 A method of constructing synthetic leader sequences
CS931192A CZ119293A3 (en) 1990-12-19 1991-12-18 Method of constructing synthetic leading peptide sequence
IE443391A IE914433A1 (en) 1990-12-19 1991-12-18 A method of constructing synthetic leader sequences
ZA919932A ZA919932B (en) 1990-12-19 1991-12-18 A method of constructing synthetic leader sequences
KR1019930701890A KR930703450A (en) 1990-12-19 1991-12-18 Construction method of synthetic leader sequence
MX9102684A MX9102684A (en) 1990-12-19 1991-12-19 METHOD TO BUILD SEQUENCES OF PEPTIDO LIDER, SYNTHETICS.
NO93932235A NO932235L (en) 1990-12-19 1993-06-17 PROCEDURE FOR PREPARING SYNTHETIC LEADER SEQUENCES
FI932831A FI932831A0 (en) 1990-12-19 1993-06-18 For the purposes of this Regulation, the following guidelines may be used

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK300090A DK300090D0 (en) 1990-12-19 1990-12-19 PROCEDURE FOR PREPARING LEADER SEQUENCES

Publications (1)

Publication Number Publication Date
DK300090D0 true DK300090D0 (en) 1990-12-19

Family

ID=8118017

Family Applications (1)

Application Number Title Priority Date Filing Date
DK300090A DK300090D0 (en) 1990-12-19 1990-12-19 PROCEDURE FOR PREPARING LEADER SEQUENCES

Country Status (17)

Country Link
EP (1) EP0563175A1 (en)
JP (1) JPH06503957A (en)
KR (1) KR930703450A (en)
AU (1) AU660161B2 (en)
CA (1) CA2098731A1 (en)
CZ (1) CZ119293A3 (en)
DK (1) DK300090D0 (en)
FI (1) FI932831A0 (en)
HU (1) HUT68751A (en)
IE (1) IE914433A1 (en)
IL (1) IL100408A0 (en)
MX (1) MX9102684A (en)
NZ (1) NZ241011A (en)
PT (1) PT99848A (en)
SK (1) SK62593A3 (en)
WO (1) WO1992011378A1 (en)
ZA (1) ZA919932B (en)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI92601C (en) * 1992-03-11 1994-12-12 Marja Makarow Procedure for secretion of yeast beneficial proteins
US5538863A (en) * 1993-07-01 1996-07-23 Immunex Corporation Expression system comprising mutant yeast strain and expression vector encoding synthetic signal peptide
US5639642A (en) * 1994-06-16 1997-06-17 Novo Nordisk A/S Synthetic leader peptide sequences
US6500645B1 (en) 1994-06-17 2002-12-31 Novo Nordisk A/S N-terminally extended proteins expressed in yeast
ZA954983B (en) * 1994-06-17 1996-02-14 Novo Nordisk As N-terminally extended proteins expressed in yeast
HRP940432B1 (en) * 1994-08-05 2003-10-31 Pliva Pharm & Chem Works Dna sequences encoding biosynthetic insulin precursors and process for preparation of insulin
CN101955921A (en) 1995-03-17 2011-01-26 诺沃奇梅兹有限公司 Novel endoglucanases
ATE395359T1 (en) 1996-03-01 2008-05-15 Novo Nordisk As PEPTIDE FOR APPETITE SUPPRESSION, COMPOSITIONS AND USE THEREOF
JP4275741B2 (en) 1996-12-13 2009-06-10 ノバルティス バクシンズ アンド ダイアグノスティックス， インコーポレーテッド Analysis and separation of platelet-derived growth factor protein
EP1049790A1 (en) 1998-01-23 2000-11-08 Novo Nordisk A/S Process for making desired polypeptides in yeast
KR20030004315A (en) 1999-12-29 2003-01-14 노보 노르디스크 에이/에스 Method for making insulin precursors and insulin precursor analogues having improved fermentation yield in yeast
AT410217B (en) * 2000-06-15 2003-03-25 Cistem Biotechnologies Gmbh VECTOR AND A METHOD FOR THE EXPRESSION AND SELECTION OF RANDOMIZED PEPTIDE SEQUENCES
AU2002249096B2 (en) 2001-03-22 2007-06-28 Novo Nordisk Health Care Ag Coagulation factor VII derivatives
ATE532858T1 (en) 2001-09-27 2011-11-15 Novo Nordisk Healthcare Ag HUMAN CLOTTING FACTOR VII POLYPEPTIDES
CN1863908B (en) 2003-09-09 2010-08-04 诺和诺德医疗保健公司 Coagulation factor vii polypeptides
JP2007532096A (en) 2003-11-14 2007-11-15 ノボ　ノルディスク　アクティーゼルスカブ Method for producing acylated insulin
AU2004295023A1 (en) 2003-12-03 2005-06-16 Novo Nordisk A/S Single-chain insulin
WO2005078116A1 (en) * 2004-01-16 2005-08-25 Qiuyun Liu A method of isolating antibacterial peptides and the isolated peptides thereof
CA2604222A1 (en) 2005-04-18 2006-10-26 Novo Nordisk A/S Il-21 variants
EP1917363B1 (en) 2005-08-16 2011-06-22 Novo Nordisk A/S Method for making mature insulin polypeptides
US20090055942A1 (en) 2005-09-14 2009-02-26 Novo Nordisk Healthcare A/G Human Coagulation Factor VII Polypeptides
US8722620B2 (en) 2006-02-27 2014-05-13 Novo Nordisk A/S Insulin derivatives
JP5503968B2 (en) 2006-09-27 2014-05-28 ノボ・ノルデイスク・エー／エス Method for producing mature insulin polypeptide
WO2009021955A1 (en) 2007-08-13 2009-02-19 Novo Nordisk A/S Rapid acting insulin analogues
RU2514430C2 (en) 2007-08-15 2014-04-27 Ново Нордиск А/С Insulin analogues with acyl and alkylene glycol group
JP5721432B2 (en) 2007-08-15 2015-05-20 ノボ・ノルデイスク・エー／エス Insulin having an acyl moiety containing an amino acid-containing alkylene glycol repeating unit
WO2010103038A1 (en) 2009-03-11 2010-09-16 Novo Nordisk A/S Interleukin-21 variants having antagonistic binding to the il-21 receptor
AU2010272483B2 (en) 2009-07-17 2016-07-21 Omeros Corporation MASP isoforms as inhibitors of complement activation
ES2550761T3 (en) 2009-11-25 2015-11-12 Novo Nordisk A/S Method for polypeptide production
WO2011067283A1 (en) 2009-12-01 2011-06-09 Novo Nordisk A/S Novel peptidyl alpha-hydroxyglycine alpha-amidating lyases
CN102791730A (en) 2010-01-22 2012-11-21 诺沃—诺迪斯克有限公司 Process for preparing FGF-21 with low degree of O-glycosylation
CA2791841C (en) 2010-03-05 2023-01-03 Rigshospitalet Chimeric inhibitor molecules of complement activation
AU2011282988A1 (en) * 2010-07-28 2013-01-31 Smartcells, Inc. Recombinantly expressed insulin polypeptides and uses thereof
SG11201403988WA (en) 2012-02-09 2014-10-30 Var2 Pharmaceuticals Aps Targeting of chondroitin sulfate glycans
CN104704118A (en) 2012-10-15 2015-06-10 诺和诺德保健Ag（股份有限公司） Coagulation factor vii polypeptides
CN105308067B (en) 2013-06-07 2020-07-24 诺和诺德股份有限公司 Method for preparing mature insulin polypeptide
ES2700547T3 (en) * 2014-02-28 2019-02-18 Novo Nordisk As Variants of alpha mating factor pro-peptide
US20210278406A1 (en) 2018-07-13 2021-09-09 Varct Diagnostic Aps Isolation of circulating cells of fetal origin using recombinant malaria protein var2csa

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK463887D0 (en) * 1987-09-07 1987-09-07 Novo Industri As GAERLEADER
CA1340772C (en) * 1987-12-30 1999-09-28 Patricia Tekamp-Olson Expression and secretion of heterologous protiens in yeast employing truncated alpha-factor leader sequences
HU213571B (en) * 1988-07-23 1997-08-28 Delta Biotechnology Ltd Process for producing peptides and dna sequences
DK105489D0 (en) * 1989-03-03 1989-03-03 Novo Nordisk As POLYPEPTIDE

Also Published As

Publication number Publication date
WO1992011378A1 (en) 1992-07-09
HUT68751A (en) 1995-07-28
PT99848A (en) 1993-06-30
KR930703450A (en) 1993-11-30
AU9134891A (en) 1992-07-22
IL100408A0 (en) 1992-09-06
EP0563175A1 (en) 1993-10-06
IE914433A1 (en) 1992-07-01
FI932831A (en) 1993-06-18
NZ241011A (en) 1993-04-28
ZA919932B (en) 1992-08-26
FI932831A0 (en) 1993-06-18
AU660161B2 (en) 1995-06-15
MX9102684A (en) 1992-06-01
JPH06503957A (en) 1994-05-12
CA2098731A1 (en) 1992-06-19
SK62593A3 (en) 1993-10-06
HU9301801D0 (en) 1993-10-28
CZ119293A3 (en) 1994-02-16

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