HU9301801D0 - Method for producing synthetic leader sequences - Google Patents
Method for producing synthetic leader sequencesInfo
- Publication number
- HU9301801D0 HU9301801D0 HU931801A HUP9301801A HU9301801D0 HU 9301801 D0 HU9301801 D0 HU 9301801D0 HU 931801 A HU931801 A HU 931801A HU P9301801 A HUP9301801 A HU P9301801A HU 9301801 D0 HU9301801 D0 HU 9301801D0
- Authority
- HU
- Hungary
- Prior art keywords
- leader sequences
- producing synthetic
- synthetic leader
- producing
- sequences
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK300090A DK300090D0 (en) | 1990-12-19 | 1990-12-19 | PROCEDURE FOR PREPARING LEADER SEQUENCES |
Publications (2)
Publication Number | Publication Date |
---|---|
HU9301801D0 true HU9301801D0 (en) | 1993-10-28 |
HUT68751A HUT68751A (en) | 1995-07-28 |
Family
ID=8118017
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9301801A HUT68751A (en) | 1990-12-19 | 1991-12-18 | A method of constructing synthetic leader sequences |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0563175A1 (en) |
JP (1) | JPH06503957A (en) |
KR (1) | KR930703450A (en) |
AU (1) | AU660161B2 (en) |
CA (1) | CA2098731A1 (en) |
CZ (1) | CZ119293A3 (en) |
DK (1) | DK300090D0 (en) |
FI (1) | FI932831A (en) |
HU (1) | HUT68751A (en) |
IE (1) | IE914433A1 (en) |
IL (1) | IL100408A0 (en) |
MX (1) | MX9102684A (en) |
NZ (1) | NZ241011A (en) |
PT (1) | PT99848A (en) |
SK (1) | SK62593A3 (en) |
WO (1) | WO1992011378A1 (en) |
ZA (1) | ZA919932B (en) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI92601C (en) * | 1992-03-11 | 1994-12-12 | Marja Makarow | Procedure for secretion of yeast beneficial proteins |
US5538863A (en) * | 1993-07-01 | 1996-07-23 | Immunex Corporation | Expression system comprising mutant yeast strain and expression vector encoding synthetic signal peptide |
US5639642A (en) * | 1994-06-16 | 1997-06-17 | Novo Nordisk A/S | Synthetic leader peptide sequences |
IL114160A (en) * | 1994-06-17 | 2006-12-31 | Novo Nordisk As | Dna constructs encoding heterologous proteins and processes for the heterologous protein production in yeast |
US6500645B1 (en) | 1994-06-17 | 2002-12-31 | Novo Nordisk A/S | N-terminally extended proteins expressed in yeast |
HRP940432B1 (en) * | 1994-08-05 | 2003-10-31 | Pliva Pharm & Chem Works | Dna sequences encoding biosynthetic insulin precursors and process for preparation of insulin |
NZ303162A (en) | 1995-03-17 | 2000-01-28 | Novo Nordisk As | Enzyme preparations comprising an enzyme exhibiting endoglucanase activity appropriate for laundry compositions for textiles |
BR9707807A (en) | 1996-03-01 | 1999-07-27 | Novo Nordisk As | Use of a pharmaceutical composition pharmaceutical composition process of treating diseases or disorders associated with the regulation of impaired appetite and use of a peptide |
DE69739319D1 (en) | 1996-12-13 | 2009-04-30 | Novartis Vaccines & Diagnostic | Method for expression of PDGF or IGR proteins in yeast |
JP2003525570A (en) | 1998-01-23 | 2003-09-02 | ノボ ノルディスク アクティーゼルスカブ | Method for producing desired polypeptide in yeast |
DE60044728D1 (en) | 1999-12-29 | 2010-09-02 | Novo Nordisk As | METHOD FOR THE PRODUCTION OF INSULIN FORECASTS AND ANALOGS OF INSULIN PROCESSORS WITH IMPROVED FERMENTATION EXPORTS IN YEAST |
AT410217B (en) * | 2000-06-15 | 2003-03-25 | Cistem Biotechnologies Gmbh | VECTOR AND A METHOD FOR THE EXPRESSION AND SELECTION OF RANDOMIZED PEPTIDE SEQUENCES |
ES2432967T3 (en) | 2001-03-22 | 2013-12-05 | Novo Nordisk Health Care Ag | Coagulation Factor VII derivatives |
ATE532858T1 (en) | 2001-09-27 | 2011-11-15 | Novo Nordisk Healthcare Ag | HUMAN CLOTTING FACTOR VII POLYPEPTIDES |
ES2381110T3 (en) | 2003-09-09 | 2012-05-23 | Novo Nordisk Health Care Ag | Coagulation Factor VII Polypeptides |
JP2007532096A (en) | 2003-11-14 | 2007-11-15 | ノボ ノルディスク アクティーゼルスカブ | Method for producing acylated insulin |
ES2369895T3 (en) | 2003-12-03 | 2011-12-07 | Novo Nordisk A/S | MONOCATENARY INSULIN. |
WO2005078116A1 (en) * | 2004-01-16 | 2005-08-25 | Qiuyun Liu | A method of isolating antibacterial peptides and the isolated peptides thereof |
ES2357550T3 (en) | 2005-04-18 | 2011-04-27 | Novo Nordisk A/S | VARIANTS OF IL-21. |
CN102660614A (en) | 2005-08-16 | 2012-09-12 | 诺沃-诺迪斯克有限公司 | Method for making mature insulin polypeptides |
US20090055942A1 (en) | 2005-09-14 | 2009-02-26 | Novo Nordisk Healthcare A/G | Human Coagulation Factor VII Polypeptides |
ATE482977T1 (en) | 2006-02-27 | 2010-10-15 | Novo Nordisk As | INSULIN DERIVATIVES |
EP2069502B1 (en) | 2006-09-27 | 2014-02-26 | Novo Nordisk A/S | Method for making maturated insulin polypeptides |
WO2009021955A1 (en) | 2007-08-13 | 2009-02-19 | Novo Nordisk A/S | Rapid acting insulin analogues |
ES2526924T3 (en) | 2007-08-15 | 2015-01-16 | Novo Nordisk A/S | Insulins with an acyl fraction comprising repetitive amino acid units containing alkylene glycol |
EP2178912B1 (en) | 2007-08-15 | 2015-07-08 | Novo Nordisk A/S | Insulin analogues with an acyl and aklylene glycol moiety |
EP2406282A1 (en) | 2009-03-11 | 2012-01-18 | Novo Nordisk A/S | Interleukin-21 variants having antagonistic binding to the il-21 receptor |
AU2010272483B2 (en) | 2009-07-17 | 2016-07-21 | Omeros Corporation | MASP isoforms as inhibitors of complement activation |
EP2504355B1 (en) | 2009-11-25 | 2015-07-22 | Novo Nordisk A/S | Method for making polypeptides |
WO2011067283A1 (en) | 2009-12-01 | 2011-06-09 | Novo Nordisk A/S | Novel peptidyl alpha-hydroxyglycine alpha-amidating lyases |
ES2543634T3 (en) | 2010-01-22 | 2015-08-20 | Novo Nordisk A/S | Process for preparing FGF-21 with low O-glycosylation grade |
JP6148013B2 (en) | 2010-03-05 | 2017-06-14 | リグショスピタレト | Chimera inhibitor molecule of complement activation |
AU2011282988A1 (en) * | 2010-07-28 | 2013-01-31 | Smartcells, Inc. | Recombinantly expressed insulin polypeptides and uses thereof |
US11787844B2 (en) | 2012-02-09 | 2023-10-17 | Var2 Pharmaceuticals Aps | Targeting of chondroitin sulfate glycans |
JP2015532307A (en) | 2012-10-15 | 2015-11-09 | ノヴォ・ノルディスク・ヘルス・ケア・アーゲー | Coagulation factor VII polypeptide |
EP3004156A1 (en) | 2013-06-07 | 2016-04-13 | Novo Nordisk A/S | Method for making mature insulin polypeptides |
US20160376330A1 (en) * | 2014-02-28 | 2016-12-29 | Novo Nordisk A/S | Mating factor alpha pro-peptide variants |
CN112789504A (en) | 2018-07-13 | 2021-05-11 | 瓦克特诊断有限责任公司 | Isolation of fetal-derived circulating cells using the recombinant malaria protein VAR2CSA |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK463887D0 (en) * | 1987-09-07 | 1987-09-07 | Novo Industri As | GAERLEADER |
CA1340772C (en) * | 1987-12-30 | 1999-09-28 | Patricia Tekamp-Olson | Expression and secretion of heterologous protiens in yeast employing truncated alpha-factor leader sequences |
JP3092811B2 (en) * | 1988-07-23 | 2000-09-25 | デルタ バイオテクノロジー リミテッド | Peptide and DNA sequences |
DK105489D0 (en) * | 1989-03-03 | 1989-03-03 | Novo Nordisk As | POLYPEPTIDE |
-
1990
- 1990-12-19 DK DK300090A patent/DK300090D0/en not_active Application Discontinuation
-
1991
- 1991-12-17 NZ NZ241011A patent/NZ241011A/en unknown
- 1991-12-18 JP JP4502056A patent/JPH06503957A/en not_active Expired - Lifetime
- 1991-12-18 CA CA002098731A patent/CA2098731A1/en not_active Abandoned
- 1991-12-18 WO PCT/DK1991/000396 patent/WO1992011378A1/en not_active Application Discontinuation
- 1991-12-18 IL IL100408A patent/IL100408A0/en unknown
- 1991-12-18 IE IE443391A patent/IE914433A1/en not_active Application Discontinuation
- 1991-12-18 SK SK62593A patent/SK62593A3/en unknown
- 1991-12-18 CZ CS931192A patent/CZ119293A3/en unknown
- 1991-12-18 AU AU91348/91A patent/AU660161B2/en not_active Ceased
- 1991-12-18 KR KR1019930701890A patent/KR930703450A/en not_active Application Discontinuation
- 1991-12-18 EP EP92901668A patent/EP0563175A1/en not_active Ceased
- 1991-12-18 ZA ZA919932A patent/ZA919932B/en unknown
- 1991-12-18 HU HU9301801A patent/HUT68751A/en unknown
- 1991-12-18 PT PT99848A patent/PT99848A/en not_active Application Discontinuation
- 1991-12-19 MX MX9102684A patent/MX9102684A/en unknown
-
1993
- 1993-06-18 FI FI932831A patent/FI932831A/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU660161B2 (en) | 1995-06-15 |
CZ119293A3 (en) | 1994-02-16 |
ZA919932B (en) | 1992-08-26 |
FI932831A0 (en) | 1993-06-18 |
WO1992011378A1 (en) | 1992-07-09 |
CA2098731A1 (en) | 1992-06-19 |
PT99848A (en) | 1993-06-30 |
IE914433A1 (en) | 1992-07-01 |
HUT68751A (en) | 1995-07-28 |
NZ241011A (en) | 1993-04-28 |
SK62593A3 (en) | 1993-10-06 |
DK300090D0 (en) | 1990-12-19 |
AU9134891A (en) | 1992-07-22 |
MX9102684A (en) | 1992-06-01 |
FI932831A (en) | 1993-06-18 |
EP0563175A1 (en) | 1993-10-06 |
IL100408A0 (en) | 1992-09-06 |
JPH06503957A (en) | 1994-05-12 |
KR930703450A (en) | 1993-11-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
DFD9 | Temporary protection cancelled due to non-payment of fee |