FI931880A7 - Sykliset iminojohdokset, menetelmä niiden valmistamiseksi ja näitä yhdisteitä sisältävät lääkeaineet - Google Patents
Sykliset iminojohdokset, menetelmä niiden valmistamiseksi ja näitä yhdisteitä sisältävät lääkeaineet Download PDFInfo
- Publication number
- FI931880A7 FI931880A7 FI931880A FI931880A FI931880A7 FI 931880 A7 FI931880 A7 FI 931880A7 FI 931880 A FI931880 A FI 931880A FI 931880 A FI931880 A FI 931880A FI 931880 A7 FI931880 A7 FI 931880A7
- Authority
- FI
- Finland
- Prior art keywords
- compounds
- preparation
- cyclic imino
- pharmaceuticals containing
- imino derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4213919A DE4213919A1 (de) | 1992-04-28 | 1992-04-28 | Cyclische iminoderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI931880A0 FI931880A0 (fi) | 1993-04-27 |
| FI931880L FI931880L (fi) | 1993-10-29 |
| FI931880A7 true FI931880A7 (fi) | 1993-10-29 |
Family
ID=6457638
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI931880A FI931880A7 (fi) | 1992-04-28 | 1993-04-27 | Sykliset iminojohdokset, menetelmä niiden valmistamiseksi ja näitä yhdisteitä sisältävät lääkeaineet |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5576444A (enExample) |
| EP (1) | EP0567966B1 (enExample) |
| JP (1) | JP3315463B2 (enExample) |
| KR (1) | KR940005569A (enExample) |
| AT (1) | ATE170509T1 (enExample) |
| AU (1) | AU662223B2 (enExample) |
| CA (1) | CA2095009A1 (enExample) |
| DE (2) | DE4213919A1 (enExample) |
| DK (1) | DK0567966T3 (enExample) |
| ES (1) | ES2121888T3 (enExample) |
| FI (1) | FI931880A7 (enExample) |
| HU (1) | HUT70039A (enExample) |
| IL (1) | IL105517A0 (enExample) |
| MX (1) | MX9302448A (enExample) |
| NO (1) | NO180045C (enExample) |
| NZ (1) | NZ247512A (enExample) |
| PL (1) | PL298717A1 (enExample) |
| TW (1) | TW232006B (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993018058A1 (en) * | 1992-03-06 | 1993-09-16 | G.D. Searle & Co. | Peptides mimics useful as platelet aggregation inhibitors |
| DE4241632A1 (de) * | 1992-12-10 | 1994-06-16 | Thomae Gmbh Dr K | Carbonsäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| PT691953E (pt) * | 1993-03-31 | 2001-01-31 | Searle & Co | 1-amidinofenil pirrolidinonas piperidinonas azetidinonas inibidoras de agregacao de plaquetas |
| ES2147210T3 (es) * | 1993-12-03 | 2000-09-01 | Hoffmann La Roche | Derivados de acido acetico como medicamentos. |
| SK79797A3 (en) * | 1994-12-23 | 1997-11-05 | Thomae Gmbh Dr K | Piperazine derivatives, medicaments containing the same, their use and process for preparing the same |
| US5691364A (en) * | 1995-03-10 | 1997-11-25 | Berlex Laboratories, Inc. | Benzamidine derivatives and their use as anti-coagulants |
| PT813525E (pt) | 1995-03-10 | 2004-02-27 | Berlex Lab | Derivados de benzamidina e sua utilizacao como anticoagulantes |
| US5612363A (en) * | 1995-06-02 | 1997-03-18 | Berlex Laboratories, Inc. | N,N-di(aryl) cyclic urea derivatives as anti-coagulants |
| US5849759A (en) * | 1995-12-08 | 1998-12-15 | Berlex Laboratories, Inc. | Naphthyl-substituted benzimidazole derivatives as anti-coagulants |
| US5994375A (en) | 1996-02-12 | 1999-11-30 | Berlex Laboratories, Inc. | Benzamidine derivatives substituted by amino acid and hydroxy acid derivatives and their use as anti-coagulants |
| WO1997033576A1 (en) * | 1996-03-12 | 1997-09-18 | Bristol-Myers Squibb Company | Carbamyl guanidine and amidine prodrugs |
| US5753635A (en) * | 1996-08-16 | 1998-05-19 | Berlex Laboratories, Inc. | Purine derivatives and their use as anti-coagulants |
| US5693641A (en) * | 1996-08-16 | 1997-12-02 | Berlex Laboratories Inc. | Bicyclic pyrimidine derivatives and their use as anti-coagulants |
| US6008234A (en) * | 1996-09-12 | 1999-12-28 | Berlex Laboratories, Inc. | Benzamidine derivatives substituted by cyclic amino acid and cyclic hydroxy acid derivatives and their use as anti-coagulants |
| WO1998011094A1 (en) | 1996-09-12 | 1998-03-19 | Schering Aktiengesellschaft | Benzamidine derivatives substituted by cyclic amino acid or cycl ic hydroxy acid derivatives and their use as anti-coagulants |
| US6004985A (en) * | 1996-10-09 | 1999-12-21 | Berlex Laboratories, Inc. | Thio acid derived monocylic N-heterocyclics as anticoagulants |
| US7109326B2 (en) * | 1997-04-15 | 2006-09-19 | Genentech, Inc. | Halo-alkoxycarbonyl prodrugs |
| US6686364B2 (en) | 1997-12-08 | 2004-02-03 | Berlex Laboratories, Inc. | Benzamidine derivatives and their use as anti-coagulants |
| US6140351A (en) * | 1997-12-19 | 2000-10-31 | Berlex Laboratories, Inc. | Ortho-anthranilamide derivatives as anti-coagulants |
| PT1040108E (pt) | 1997-12-19 | 2004-06-30 | Schering Ag | Derivados de orto-antranilamida como anticoagulantes |
| US6114532A (en) * | 1998-02-03 | 2000-09-05 | Boehringer Ingelheim Pharma Kg | Bicyclic heterocycles, the preparation thereof, and their use as pharmaceuticals |
| CA2319494A1 (en) * | 1998-02-03 | 1999-08-12 | Boehringer Ingelheim Pharma Kg | 5-membered heterocyclic condensed benzoderivatives, the preparation thereof and their use as pharmaceuticals |
| DE19844787A1 (de) * | 1998-09-30 | 2000-04-13 | Boehringer Ingelheim Pharma | Disubstituierte Pyrrolidinone, diese Verbindung enthaltende Arzneimittel und deren Verwendung sowie ihre Herstellung |
| US6262088B1 (en) | 1998-11-19 | 2001-07-17 | Berlex Laboratories, Inc. | Polyhydroxylated monocyclic N-heterocyclic derivatives as anti-coagulants |
| US6127376A (en) | 1998-12-04 | 2000-10-03 | Berlex Laboratories, Inc. | Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants |
| US6350761B1 (en) | 1999-07-30 | 2002-02-26 | Berlex Laboratories, Inc. | Benzenamine derivatives as anti-coagulants |
| US7232924B2 (en) | 2001-06-11 | 2007-06-19 | Xenoport, Inc. | Methods for synthesis of acyloxyalkyl derivatives of GABA analogs |
| US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US6818787B2 (en) | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| JP5440976B2 (ja) * | 2009-01-14 | 2014-03-12 | ホクト株式会社 | 血小板凝集抑制剤 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2123288A (en) * | 1982-07-16 | 1984-02-01 | Wellcome Found | Anti-thrombotic agent |
| EP0194548A3 (de) * | 1985-03-12 | 1988-08-17 | Dr. Karl Thomae GmbH | Neue Sulfonylaminoäthylverbindungen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| EP0196184B1 (en) * | 1985-03-16 | 1992-09-16 | The Wellcome Foundation Limited | Aryl derivatives |
| DE3823299A1 (de) * | 1988-07-07 | 1990-01-11 | Schering Ag | Substituierte phenyl-pyrrolidin-2-one, -oxazolidin-2-one und -imidazolidin-2-one, ihre herstellung sowie verwendung in arzneimitteln |
| JPH02247166A (ja) * | 1989-03-17 | 1990-10-02 | Taisho Pharmaceut Co Ltd | ３―ピロリン―２―オン誘導体 |
| DE3932403A1 (de) * | 1989-05-12 | 1991-04-11 | Thomae Gmbh Dr K | Neue arylsulfonamide, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| US5026861A (en) * | 1989-07-17 | 1991-06-25 | Merrell Dow Pharmaceuticals | Substituted 1,5-dihydro-4-(N-methylhydroxylamino)-2H-pyrrol-2-ones |
| DE4035961A1 (de) * | 1990-11-02 | 1992-05-07 | Thomae Gmbh Dr K | Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| DE4107857A1 (de) * | 1991-03-12 | 1992-09-17 | Thomae Gmbh Dr K | Cyclische harnstoffderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| DE4124942A1 (de) * | 1991-07-27 | 1993-01-28 | Thomae Gmbh Dr K | 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE4127404A1 (de) * | 1991-08-19 | 1993-02-25 | Thomae Gmbh Dr K | Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
-
1992
- 1992-04-28 DE DE4213919A patent/DE4213919A1/de not_active Withdrawn
-
1993
- 1993-03-09 TW TW082101712A patent/TW232006B/zh active
- 1993-04-26 AT AT93106724T patent/ATE170509T1/de not_active IP Right Cessation
- 1993-04-26 DK DK93106724T patent/DK0567966T3/da active
- 1993-04-26 EP EP93106724A patent/EP0567966B1/de not_active Expired - Lifetime
- 1993-04-26 DE DE59308940T patent/DE59308940D1/de not_active Expired - Fee Related
- 1993-04-26 US US08/053,037 patent/US5576444A/en not_active Expired - Lifetime
- 1993-04-26 ES ES93106724T patent/ES2121888T3/es not_active Expired - Lifetime
- 1993-04-27 NZ NZ247512A patent/NZ247512A/en unknown
- 1993-04-27 MX MX9302448A patent/MX9302448A/es unknown
- 1993-04-27 KR KR1019930007059A patent/KR940005569A/ko not_active Withdrawn
- 1993-04-27 NO NO931526A patent/NO180045C/no unknown
- 1993-04-27 PL PL29871793A patent/PL298717A1/xx unknown
- 1993-04-27 JP JP09993093A patent/JP3315463B2/ja not_active Expired - Fee Related
- 1993-04-27 CA CA002095009A patent/CA2095009A1/en not_active Abandoned
- 1993-04-27 HU HU9301222A patent/HUT70039A/hu unknown
- 1993-04-27 FI FI931880A patent/FI931880A7/fi not_active Application Discontinuation
- 1993-04-27 IL IL105517A patent/IL105517A0/xx unknown
- 1993-04-28 AU AU38222/93A patent/AU662223B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| MX9302448A (es) | 1993-10-01 |
| IL105517A0 (en) | 1993-08-18 |
| EP0567966A1 (de) | 1993-11-03 |
| US5576444A (en) | 1996-11-19 |
| NO931526L (no) | 1993-10-29 |
| DE59308940D1 (de) | 1998-10-08 |
| FI931880L (fi) | 1993-10-29 |
| NZ247512A (en) | 1995-12-21 |
| KR940005569A (ko) | 1994-03-21 |
| NO931526D0 (no) | 1993-04-27 |
| NO180045B (no) | 1996-10-28 |
| HU9301222D0 (en) | 1993-07-28 |
| AU3822293A (en) | 1993-11-04 |
| HUT70039A (en) | 1995-09-28 |
| EP0567966B1 (de) | 1998-09-02 |
| TW232006B (enExample) | 1994-10-11 |
| CA2095009A1 (en) | 1993-10-29 |
| DK0567966T3 (da) | 1999-05-31 |
| FI931880A0 (fi) | 1993-04-27 |
| JP3315463B2 (ja) | 2002-08-19 |
| ES2121888T3 (es) | 1998-12-16 |
| NO180045C (no) | 1997-02-05 |
| JPH0673001A (ja) | 1994-03-15 |
| DE4213919A1 (de) | 1993-11-04 |
| ATE170509T1 (de) | 1998-09-15 |
| PL298717A1 (en) | 1994-01-24 |
| AU662223B2 (en) | 1995-08-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed |