FI923458A - 4,5-cykloalkano-3-benzazepin-7-ol- derivat och deras anvaendning. - Google Patents

4,5-cykloalkano-3-benzazepin-7-ol- derivat och deras anvaendning. Download PDF

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Publication number
FI923458A
FI923458A FI923458A FI923458A FI923458A FI 923458 A FI923458 A FI 923458A FI 923458 A FI923458 A FI 923458A FI 923458 A FI923458 A FI 923458A FI 923458 A FI923458 A FI 923458A
Authority
FI
Finland
Prior art keywords
alkoxy
alkyl
pct
phenyl
substituted phenyl
Prior art date
Application number
FI923458A
Other languages
English (en)
Other versions
FI923458A0 (fi
Inventor
Theodros Asberom
Edward O'connor
Joel Gilbert Berger
John Welch Clader
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of FI923458A publication Critical patent/FI923458A/fi
Publication of FI923458A0 publication Critical patent/FI923458A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/32—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems containing carbocyclic rings other than six-membered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI923458A 1990-02-02 1992-07-31 4,5-cykloalkano-3-benzazepin-7-ol- derivat och deras anvaendning. FI923458A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47442890A 1990-02-02 1990-02-02
PCT/US1991/000503 WO1991011437A1 (en) 1990-02-02 1991-01-31 4,5-cycloalkano-3-benzazepin-7-ol-derivatives and their use

Publications (2)

Publication Number Publication Date
FI923458A true FI923458A (fi) 1992-07-31
FI923458A0 FI923458A0 (fi) 1992-07-31

Family

ID=23883493

Family Applications (1)

Application Number Title Priority Date Filing Date
FI923458A FI923458A0 (fi) 1990-02-02 1992-07-31 4,5-cykloalkano-3-benzazepin-7-ol- derivat och deras anvaendning.

Country Status (12)

Country Link
US (1) US5362728A (fi)
EP (1) EP0513174B1 (fi)
JP (1) JPH0613474B2 (fi)
KR (1) KR927003537A (fi)
AT (1) ATE126511T1 (fi)
AU (1) AU646432B2 (fi)
CA (1) CA2075181C (fi)
DE (1) DE69112201T2 (fi)
ES (1) ES2075429T3 (fi)
FI (1) FI923458A0 (fi)
OA (1) OA09662A (fi)
WO (1) WO1991011437A1 (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1008622A3 (fr) * 1993-12-09 1996-06-04 Egyt Gyogyszervegyeszeti Gyar Derives de l'epi-epibatidine.
DK0933993T3 (da) 1996-06-14 2006-08-14 Biocryst Pharm Inc Substituerede cyclopentanforbindelser, der er egnede som neuraminidaseinhibitorer
AU728332B2 (en) * 1997-06-23 2001-01-04 Kioka Gaishi Kogyo Kabushiki Kaisha Lock nut and attaching/removing tool for the same
BR9813480A (pt) * 1997-12-17 2000-10-10 Biocryst Pharm Inc Compostos inibidores de neuraminidase de ciclopentano substituìdo, composição e métodos de inibição da neuraminidase do vìrus da influenza- e de tratamento de infecção por vìrus da influenza-
US6503745B1 (en) 1998-11-05 2003-01-07 Biocryst Pharmaceuticals, Inc. Cyclopentane and cyclopentene compounds and use for detecting influenza virus
US7411093B2 (en) 2004-12-20 2008-08-12 Hoffman-La Roche Inc. Aminocycloalkanes as DPP-IV inhibitors
WO2007027651A2 (en) * 2005-08-30 2007-03-08 Abbott Laboratories Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-iv (dpp-iv)
MX2009012685A (es) 2007-05-31 2009-12-14 Sepracor Inc Cicloalquilaminas sustituidas con fenilo como inhibidores de la reabsorcion de monoamina.
CN103189053A (zh) 2010-09-01 2013-07-03 艾尼纳制药公司 用于体重控制的5-ht2c激动剂的调节释放剂型
MX2013002418A (es) 2010-09-01 2013-08-01 Arena Pharm Inc Administracion de lorcaserina a individuos con daño renal.

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3393192A (en) * 1965-04-26 1968-07-16 Schering Corp Novel benzazepines
GB1118688A (en) * 1967-02-17 1968-07-03 Scherico Ltd Novel benzazepines and process for making same
CH481110A (de) * 1967-02-17 1969-11-15 Geigy Ag J R Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
US3609138A (en) * 1967-12-22 1971-09-28 Ciba Geigy Corp 1-aryl-3-benzazepines
US3752892A (en) * 1970-03-11 1973-08-14 Ciba Geigy Corp Anorexigenic tetrahydrobenzazepine derivative method and composition thereof
US4011319A (en) * 1975-07-02 1977-03-08 Smithkline Corporation Pharmaceutical compositions and methods involving benzazepine derivatives
US4284555A (en) * 1979-04-27 1981-08-18 Schering Corporation 7-Chloro-8(substituted amino carbonyloxy)-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4477378A (en) * 1980-02-05 1984-10-16 Schering Corp. Esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
KR900007781B1 (ko) * 1986-01-16 1990-10-20 쉐링 코포레이션 융합된 벤즈아제핀
US4973586A (en) * 1986-01-16 1990-11-27 Schering Corporation Fused benzazepines, compositions of, and medical use thereof
JPH0678317B2 (ja) * 1987-07-15 1994-10-05 シェリング・コーポレーション 縮合ベンズアゼピン

Also Published As

Publication number Publication date
AU646432B2 (en) 1994-02-24
EP0513174A1 (en) 1992-11-19
KR927003537A (ko) 1992-12-18
DE69112201T2 (de) 1996-02-15
ES2075429T3 (es) 1995-10-01
JPH05504769A (ja) 1993-07-22
ATE126511T1 (de) 1995-09-15
DE69112201D1 (de) 1995-09-21
CA2075181C (en) 1997-12-09
US5362728A (en) 1994-11-08
WO1991011437A1 (en) 1991-08-08
CA2075181A1 (en) 1991-08-03
OA09662A (en) 1993-05-15
JPH0613474B2 (ja) 1994-02-23
FI923458A0 (fi) 1992-07-31
EP0513174B1 (en) 1995-08-16
AU7243291A (en) 1991-08-21

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Legal Events

Date Code Title Description
FD Application lapsed