FI922875A7 - Reniiniä estävät yhdisteet, menetelmä niiden valmistamiseksi ja niidenkäyttö - Google Patents

Reniiniä estävät yhdisteet, menetelmä niiden valmistamiseksi ja niidenkäyttö Download PDF

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Publication number
FI922875A7
FI922875A7 FI922875A FI922875A FI922875A7 FI 922875 A7 FI922875 A7 FI 922875A7 FI 922875 A FI922875 A FI 922875A FI 922875 A FI922875 A FI 922875A FI 922875 A7 FI922875 A7 FI 922875A7
Authority
FI
Finland
Prior art keywords
renin
preparation
inhibiting compounds
inhibiting
compounds
Prior art date
Application number
FI922875A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI922875L (fi
FI922875A0 (fi
Inventor
Hansjörg Urbach
Wolfgang Linz
Dieter Ruppert
Rainer Henning
Holger Heitsch
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI922875A0 publication Critical patent/FI922875A0/fi
Publication of FI922875L publication Critical patent/FI922875L/fi
Publication of FI922875A7 publication Critical patent/FI922875A7/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI922875A 1991-06-21 1992-06-18 Reniiniä estävät yhdisteet, menetelmä niiden valmistamiseksi ja niidenkäyttö FI922875A7 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4120510 1991-06-21

Publications (3)

Publication Number Publication Date
FI922875A0 FI922875A0 (fi) 1992-06-18
FI922875L FI922875L (fi) 1992-12-22
FI922875A7 true FI922875A7 (fi) 1992-12-22

Family

ID=6434452

Family Applications (1)

Application Number Title Priority Date Filing Date
FI922875A FI922875A7 (fi) 1991-06-21 1992-06-18 Reniiniä estävät yhdisteet, menetelmä niiden valmistamiseksi ja niidenkäyttö

Country Status (14)

Country Link
EP (1) EP0519433A1 (cg-RX-API-DMAC7.html)
JP (1) JPH05186461A (cg-RX-API-DMAC7.html)
KR (1) KR930000506A (cg-RX-API-DMAC7.html)
CN (1) CN1068112A (cg-RX-API-DMAC7.html)
BR (1) BR9202325A (cg-RX-API-DMAC7.html)
CA (1) CA2071744A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ190692A3 (cg-RX-API-DMAC7.html)
FI (1) FI922875A7 (cg-RX-API-DMAC7.html)
HU (1) HUT61744A (cg-RX-API-DMAC7.html)
IE (1) IE921995A1 (cg-RX-API-DMAC7.html)
MX (1) MX9203070A (cg-RX-API-DMAC7.html)
NO (1) NO922426L (cg-RX-API-DMAC7.html)
PL (1) PL294870A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA924522B (cg-RX-API-DMAC7.html)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071895A (en) 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
RU2126794C1 (ru) 1992-03-11 1999-02-27 Нархекс Лимитед Аминопроизводные оксо- или гидроксизамещенных гидразинов, способ их получения и фармацевтические композиции для ингибирования ретровирусной протеазы
US5888992A (en) 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
MXPA93002392A (es) 1992-03-11 2005-02-04 Narhex Ltd Derivados amino de hidrocarburos-oxo e hidroxi-substituidos.
IL110898A0 (en) * 1993-09-10 1994-11-28 Narhex Australia Pty Ltd Polar-substituted hydrocarbons
US6369080B2 (en) 1996-10-11 2002-04-09 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6194435B1 (en) 1996-10-11 2001-02-27 Cor Therapeutics, Inc. Lactams as selective factor Xa inhibitors
US6063794A (en) 1996-10-11 2000-05-16 Cor Therapeutics Inc. Selective factor Xa inhibitors
US6262047B1 (en) 1996-10-11 2001-07-17 Cor Therapeutics, Inc. Selective factor Xa inhibitors
EP0977773A1 (en) 1997-04-14 2000-02-09 Cor Therapeutics, Inc. SELECTIVE FACTOR Xa INHIBITORS
NZ500353A (en) 1997-04-14 2002-02-01 Cor Therapeutics Inc Cyclic diaza compounds that are selective inhibitors of factor Xa
NZ500351A (en) * 1997-04-14 2001-10-26 Cor Therapeutics Inc Cyclic diaza compounds as selective factor Xa inhibitors
US6218382B1 (en) 1997-08-11 2001-04-17 Cor Therapeutics, Inc Selective factor Xa inhibitors
US6228854B1 (en) 1997-08-11 2001-05-08 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6333321B1 (en) 1997-08-11 2001-12-25 Cor Therapeutics, Inc. Selective factor Xa inhibitors
ECSP003707A (es) * 1999-10-13 2002-05-23 Novartis Ag Diazepanes
US6399599B1 (en) 1999-10-13 2002-06-04 Novartis Ag Substituted 2-oxo-1,4-diazacycloalkanes
WO2002060894A2 (en) 2001-01-30 2002-08-08 Bristol-Myers Squibb Company Sulfonamide lactam inhibitors of factor xa
WO2005070871A2 (en) 2004-01-23 2005-08-04 Speedel Experimenta Ag Amino alcohol derivatives and their activity as renin inhibitors
BRPI0506490A (pt) * 2004-01-23 2007-02-13 Speedel Experimenta Ag compostos orgánicos

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL81234A (en) * 1986-01-16 1992-09-06 Abbott Lab Peptidylaminodiols,process for their preparation and pharmaceutical compositions comprising them
GB8707412D0 (en) * 1987-03-27 1987-04-29 Fujisawa Pharmaceutical Co Peptide compounds
IL87614A0 (en) * 1987-09-16 1989-01-31 Abbott Lab Peptidylheterocycles
ATE165085T1 (de) * 1987-09-29 1998-05-15 Banyu Pharma Co Ltd N-acylaminosäurederivate und deren verwendung
IL92011A0 (en) * 1988-10-19 1990-07-12 Abbott Lab Heterocyclic peptide renin inhibitors
DE3839559A1 (de) * 1988-11-24 1990-05-31 Hoechst Ag Renin-hemmende aminodiol-derivate
DE3841732A1 (de) * 1988-12-10 1990-06-13 Hoechst Ag Dipeptid-derivate mit enzym-inhibitorischer wirkung
DE3913272A1 (de) * 1989-04-22 1990-10-25 Hoechst Ag Dipeptid-derivate mit enzym-inhibitorischer wirkung

Also Published As

Publication number Publication date
FI922875L (fi) 1992-12-22
CN1068112A (zh) 1993-01-20
EP0519433A1 (de) 1992-12-23
PL294870A1 (cg-RX-API-DMAC7.html) 1993-02-08
MX9203070A (es) 1992-12-01
BR9202325A (pt) 1993-01-19
CA2071744A1 (en) 1992-12-22
NO922426D0 (no) 1992-06-19
NO922426L (no) 1992-12-22
JPH05186461A (ja) 1993-07-27
FI922875A0 (fi) 1992-06-18
IE921995A1 (en) 1992-12-30
KR930000506A (ko) 1993-01-15
HUT61744A (en) 1993-03-01
CZ190692A3 (en) 1993-01-13
HU9202062D0 (en) 1992-10-28
ZA924522B (en) 1993-02-24

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