ZA924522B - Compounds with renin-inhibiting properties,a process for the preparation thereof and the use thereof - Google Patents
Compounds with renin-inhibiting properties,a process for the preparation thereof and the use thereofInfo
- Publication number
- ZA924522B ZA924522B ZA924522A ZA924522A ZA924522B ZA 924522 B ZA924522 B ZA 924522B ZA 924522 A ZA924522 A ZA 924522A ZA 924522 A ZA924522 A ZA 924522A ZA 924522 B ZA924522 B ZA 924522B
- Authority
- ZA
- South Africa
- Prior art keywords
- renin
- compounds
- preparation
- inhibiting properties
- inhibiting
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4120510 | 1991-06-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA924522B true ZA924522B (en) | 1993-02-24 |
Family
ID=6434452
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA924522A ZA924522B (en) | 1991-06-21 | 1992-06-19 | Compounds with renin-inhibiting properties,a process for the preparation thereof and the use thereof |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0519433A1 (en) |
JP (1) | JPH05186461A (en) |
KR (1) | KR930000506A (en) |
CN (1) | CN1068112A (en) |
BR (1) | BR9202325A (en) |
CA (1) | CA2071744A1 (en) |
CZ (1) | CZ190692A3 (en) |
FI (1) | FI922875A (en) |
HU (1) | HUT61744A (en) |
IE (1) | IE921995A1 (en) |
MX (1) | MX9203070A (en) |
NO (1) | NO922426L (en) |
PL (1) | PL294870A1 (en) |
ZA (1) | ZA924522B (en) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5888992A (en) | 1992-03-11 | 1999-03-30 | Narhex Limited | Polar substituted hydrocarbons |
US6071895A (en) | 1992-03-11 | 2000-06-06 | Narhex Limited | Polar-substituted hydrocarbons |
ATE253050T1 (en) | 1992-03-11 | 2003-11-15 | Narhex Ltd | AMINE DERIVATIVES OF OXO- AND HYDROXY-SUBSTITUTED HYDROCARBONS |
RU2126794C1 (en) | 1992-03-11 | 1999-02-27 | Нархекс Лимитед | Amino-derivatives of oxo- or hydroxy-substituted hydrazines, method of their synthesis and pharmaceutical compositions for inhibition of retrovirus protease |
IL110898A0 (en) * | 1993-09-10 | 1994-11-28 | Narhex Australia Pty Ltd | Polar-substituted hydrocarbons |
US6063794A (en) | 1996-10-11 | 2000-05-16 | Cor Therapeutics Inc. | Selective factor Xa inhibitors |
US6369080B2 (en) | 1996-10-11 | 2002-04-09 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
US6262047B1 (en) | 1996-10-11 | 2001-07-17 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
US6194435B1 (en) | 1996-10-11 | 2001-02-27 | Cor Therapeutics, Inc. | Lactams as selective factor Xa inhibitors |
EP0977773A1 (en) | 1997-04-14 | 2000-02-09 | Cor Therapeutics, Inc. | SELECTIVE FACTOR Xa INHIBITORS |
US6133256A (en) * | 1997-04-14 | 2000-10-17 | Cor Therapeutics Inc | Selective factor Xa inhibitors |
NZ500353A (en) | 1997-04-14 | 2002-02-01 | Cor Therapeutics Inc | Cyclic diaza compounds that are selective inhibitors of factor Xa |
US6228854B1 (en) | 1997-08-11 | 2001-05-08 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
US6218382B1 (en) | 1997-08-11 | 2001-04-17 | Cor Therapeutics, Inc | Selective factor Xa inhibitors |
US6333321B1 (en) | 1997-08-11 | 2001-12-25 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
US6399599B1 (en) | 1999-10-13 | 2002-06-04 | Novartis Ag | Substituted 2-oxo-1,4-diazacycloalkanes |
ECSP003707A (en) * | 1999-10-13 | 2002-05-23 | Novartis Ag | DIAZEPANES |
WO2002060894A2 (en) | 2001-01-30 | 2002-08-08 | Bristol-Myers Squibb Company | Sulfonamide lactam inhibitors of factor xa |
TW200530214A (en) * | 2004-01-23 | 2005-09-16 | Speedel Experimenta Ag | Organic compounds |
WO2005070871A2 (en) * | 2004-01-23 | 2005-08-04 | Speedel Experimenta Ag | Amino alcohol derivatives and their activity as renin inhibitors |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL81234A (en) * | 1986-01-16 | 1992-09-06 | Abbott Lab | Peptidylaminodiols,process for their preparation and pharmaceutical compositions comprising them |
GB8707412D0 (en) * | 1987-03-27 | 1987-04-29 | Fujisawa Pharmaceutical Co | Peptide compounds |
IL87614A0 (en) * | 1987-09-16 | 1989-01-31 | Abbott Lab | Peptidylheterocycles |
DE3856166T2 (en) * | 1987-09-29 | 1998-08-06 | Banyu Pharma Co Ltd | N-acylamino acid derivatives and their use |
IL92011A0 (en) * | 1988-10-19 | 1990-07-12 | Abbott Lab | Heterocyclic peptide renin inhibitors |
DE3839559A1 (en) * | 1988-11-24 | 1990-05-31 | Hoechst Ag | RENIN-INHIBITING AMINODIOL DERIVATIVES |
DE3841732A1 (en) * | 1988-12-10 | 1990-06-13 | Hoechst Ag | DIPEPTIDE DERIVATIVES WITH ENZYME-INHIBITOR EFFECT |
DE3913272A1 (en) * | 1989-04-22 | 1990-10-25 | Hoechst Ag | DIPEPTIDE DERIVATIVES WITH ENZYME-INHIBITOR EFFECT |
-
1992
- 1992-06-11 PL PL29487092A patent/PL294870A1/xx unknown
- 1992-06-17 EP EP92110244A patent/EP0519433A1/en not_active Withdrawn
- 1992-06-18 FI FI922875A patent/FI922875A/en unknown
- 1992-06-19 ZA ZA924522A patent/ZA924522B/en unknown
- 1992-06-19 NO NO92922426A patent/NO922426L/en unknown
- 1992-06-19 HU HU9202062A patent/HUT61744A/en unknown
- 1992-06-19 CZ CS921906A patent/CZ190692A3/en unknown
- 1992-06-19 BR BR929202325A patent/BR9202325A/en not_active Application Discontinuation
- 1992-06-19 CA CA002071744A patent/CA2071744A1/en not_active Abandoned
- 1992-06-19 JP JP4160476A patent/JPH05186461A/en active Pending
- 1992-06-19 MX MX9203070A patent/MX9203070A/en unknown
- 1992-06-19 KR KR1019920010653A patent/KR930000506A/en not_active Application Discontinuation
- 1992-06-20 CN CN92104887A patent/CN1068112A/en active Pending
- 1992-07-01 IE IE199592A patent/IE921995A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
PL294870A1 (en) | 1993-02-08 |
FI922875A0 (en) | 1992-06-18 |
CA2071744A1 (en) | 1992-12-22 |
NO922426D0 (en) | 1992-06-19 |
BR9202325A (en) | 1993-01-19 |
HUT61744A (en) | 1993-03-01 |
EP0519433A1 (en) | 1992-12-23 |
IE921995A1 (en) | 1992-12-30 |
HU9202062D0 (en) | 1992-10-28 |
JPH05186461A (en) | 1993-07-27 |
KR930000506A (en) | 1993-01-15 |
NO922426L (en) | 1992-12-22 |
FI922875A (en) | 1992-12-22 |
CN1068112A (en) | 1993-01-20 |
CZ190692A3 (en) | 1993-01-13 |
MX9203070A (en) | 1992-12-01 |
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