FI912563A0 - Azolderivat. - Google Patents

Azolderivat.

Info

Publication number
FI912563A0
FI912563A0 FI912563A FI912563A FI912563A0 FI 912563 A0 FI912563 A0 FI 912563A0 FI 912563 A FI912563 A FI 912563A FI 912563 A FI912563 A FI 912563A FI 912563 A0 FI912563 A0 FI 912563A0
Authority
FI
Finland
Prior art keywords
azolderivat
Prior art date
Application number
FI912563A
Other languages
English (en)
Other versions
FI912563A (fi
Inventor
Peter William Rodney Caulkett
Geraint Jones
Michael George Collis
Simon Martin Poucher
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909011914A external-priority patent/GB9011914D0/en
Priority claimed from GB909011913A external-priority patent/GB9011913D0/en
Priority claimed from GB919101379A external-priority patent/GB9101379D0/en
Priority claimed from GB919101380A external-priority patent/GB9101380D0/en
Priority claimed from GB919104125A external-priority patent/GB9104125D0/en
Application filed by Ici Plc filed Critical Ici Plc
Publication of FI912563A0 publication Critical patent/FI912563A0/fi
Publication of FI912563A publication Critical patent/FI912563A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
FI912563A 1990-05-29 1991-05-28 Azolderivat. FI912563A (fi)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB909011914A GB9011914D0 (en) 1990-05-29 1990-05-29 Heterocyclic compounds
GB909011913A GB9011913D0 (en) 1990-05-29 1990-05-29 Azole derivatives
GB919101379A GB9101379D0 (en) 1991-01-22 1991-01-22 Heterocyclic compounds
GB919101380A GB9101380D0 (en) 1991-01-22 1991-01-22 Azole derivatives
GB919104125A GB9104125D0 (en) 1991-02-27 1991-02-27 Azole derivatives

Publications (2)

Publication Number Publication Date
FI912563A0 true FI912563A0 (fi) 1991-05-28
FI912563A FI912563A (fi) 1991-11-30

Family

ID=27516979

Family Applications (1)

Application Number Title Priority Date Filing Date
FI912563A FI912563A (fi) 1990-05-29 1991-05-28 Azolderivat.

Country Status (20)

Country Link
US (1) US5270311A (fi)
EP (1) EP0459702A1 (fi)
JP (1) JP2504879B2 (fi)
KR (1) KR910020012A (fi)
CN (1) CN1056879A (fi)
AP (1) AP248A (fi)
AU (1) AU642494B2 (fi)
CA (1) CA2043424A1 (fi)
CS (1) CS159591A3 (fi)
FI (1) FI912563A (fi)
GB (1) GB2244487B (fi)
HU (1) HUT61311A (fi)
IE (1) IE911818A1 (fi)
IL (1) IL98316A (fi)
NO (1) NO178401C (fi)
NZ (1) NZ238288A (fi)
OA (1) OA09358A (fi)
PT (1) PT97776A (fi)
RO (1) RO109542B1 (fi)
YU (1) YU47812B (fi)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5356894A (en) * 1990-05-29 1994-10-18 Rodney Peter W Morpholinyl substituted [1,2,4]-triazolo[1,5-a]triazine as antagonist
GB9226735D0 (en) * 1992-12-22 1993-02-17 Ici Plc Azole derivatives
EP0459702A1 (en) * 1990-05-29 1991-12-04 Zeneca Limited Azole Derivatives
GB9111130D0 (en) * 1991-05-23 1991-07-17 Ici Plc Azole derivatives
GB9111131D0 (en) * 1991-05-23 1991-07-17 Ici Plc Heterocyclic compounds
GB9125001D0 (en) * 1991-11-25 1992-01-22 Ici Plc Heterocyclic compounds
GB9125002D0 (en) * 1991-11-25 1992-01-22 Ici Plc Azole derivatives
GB9124968D0 (en) * 1991-11-25 1992-01-22 Ici Plc Chemical process
WO1995003806A1 (fr) * 1993-07-27 1995-02-09 Kyowa Hakko Kogyo Co., Ltd. Remede contre la maladie de parkinson
DE69426620T2 (de) * 1993-09-06 2001-06-21 Kyowa Hakko Kogyo Kk Antidepressiva
AU743910B2 (en) 1997-03-24 2002-02-07 Kyowa Hakko Kirin Co., Ltd. {1,2,4}triazolo{1,5-c}pyrimidine derivatives
US6060481A (en) * 1998-05-28 2000-05-09 The Penn State Research Foundation Method for improving insulin sensitivity using an adenosine receptor antagonist
CN1328560A (zh) * 1998-09-22 2001-12-26 协和发酵工业株式会社 [1,2,4]三唑并[1,5-c]嘧啶衍生物
JPWO2004029056A1 (ja) * 2002-09-24 2006-01-26 協和醗酵工業株式会社 [1,2,4]トリアゾロ[1,5−c]ピリミジン誘導体
US7329658B2 (en) * 2003-02-06 2008-02-12 Pfizer Inc Cannabinoid receptor ligands and uses thereof
WO2004092172A2 (en) * 2003-04-09 2004-10-28 Biogen Idec Ma Inc. Triazolo[1,5-c]pyrimidines and pyrazolo[1,5-c]pyrimidines useful as a2a adenosin e receptor antagonists
WO2004092170A2 (en) * 2003-04-09 2004-10-28 Biogen Idec Ma Inc. Triazolotriazines and pyrazolotriazines useful as a2a adenosine receptor antagon ists
EP1615931A1 (en) 2003-04-09 2006-01-18 Biogen Idec MA Inc. Triazolopyrazines and methods of making and using the same
US7834014B2 (en) 2003-04-09 2010-11-16 Biogen Idec Ma Inc. A2a adenosine receptor antagonists
WO2004110454A1 (ja) * 2003-06-13 2004-12-23 Ishihara Sangyo Kaisha, Ltd. アデノシンA2a受容体アゴニストの投与が必要な疾患を治療又は予防するための組成物
US7652041B2 (en) 2005-01-14 2010-01-26 Millennium Pharmaceuticals, Inc. Cinnamide and hydrocinnamide derivatives with kinase inhibitory activity
RU2015126797A (ru) 2012-12-06 2017-01-12 Сименс Акциенгезелльшафт Система и способ введения тепла в геологическую формацию при помощи электромагнитной индукции
CN106916073A (zh) * 2017-01-20 2017-07-04 上海巧坤化工科技有限公司 一种大麦芽碱盐酸盐的合成方法
US20210032253A1 (en) * 2018-02-06 2021-02-04 Jiangsu Hengrui Medicine Co., Ltd. Pyrazolo[1,5-a][1,3,5]triazine-2-amine derivative, preparation method therefor and medical use thereof
CA3103068A1 (en) * 2018-06-26 2020-01-02 Zhejiang Vimgreen Pharmaceuticals, Ltd Triazolotriazine derivatives as a2a receptor antagonists
CN111051309B (zh) * 2018-06-26 2023-05-26 浙江春禾医药科技有限公司 可用作a2a受体拮抗剂的三唑并三嗪衍生物
BE1026602B1 (fr) 2018-09-27 2020-06-18 Iteos Therapeutics S A Inhibiteurs d’a2a ne penetrant pas dans le cerveau et methodes d’utilisation dans le traitement de cancers
WO2020103939A1 (zh) * 2018-11-22 2020-05-28 上海科技大学 三唑并环类化合物、其制备方法、中间体和应用
CN112608316B (zh) * 2019-07-30 2022-10-21 厦门宝太生物科技股份有限公司 一种吡唑并三嗪类腺苷受体拮抗剂
CN114901665A (zh) * 2019-12-26 2022-08-12 浙江春禾医药科技有限公司 三唑并三嗪衍生物在治疗疾病中的用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3846423A (en) * 1972-06-08 1974-11-05 Icn Pharmaceuticals Pyrazolo (1,5a) 1,3,5-triazines
BE815405A (en) * 1973-05-22 1974-11-22 Pyrazolo(1,5-a)-s-triazines - and their salts, with bronchospasmolytic activity
US3995039A (en) * 1975-05-27 1976-11-30 Merck & Co., Inc. Pyrazolo [1,5-a] [1,3,5] triazines
GB1579932A (en) * 1976-05-12 1980-11-26 Ici Ltd Herbicidal triazolotriazines
GB2016002B (en) * 1978-01-09 1982-05-06 Aron Sa Amino derivatives of pyrazolo(1,5-a)s triazine
AU2192683A (en) * 1982-12-30 1984-07-05 Biomeasure Incorporated Pyrazolo(1,5-alpha)-1,3,5-triazines
CA1267143A (en) * 1985-06-06 1990-03-27 Sun H. Kim Anti-arthritic 7-phenylpyrazole[1,5-a]-1,3,5- triazine derivatives
US4824834A (en) * 1986-10-31 1989-04-25 Otsuka Pharmaceutical Company, Limited Pyrazolotriazine compounds
US4734413A (en) * 1987-03-02 1988-03-29 Riker Laboratories, Inc. Substituted 1,2,4-triazolo[1,5-A]triazines as bronchodilators
EP0297651B1 (en) * 1987-06-29 1993-11-03 Duphar International Research B.V Anellated indole derivatives
US4970142A (en) * 1989-02-16 1990-11-13 Konica Corporation Silver halide photographic light-sensitive material containing cyan coupler
EP0459702A1 (en) * 1990-05-29 1991-12-04 Zeneca Limited Azole Derivatives

Also Published As

Publication number Publication date
NO178401C (no) 1996-03-20
KR910020012A (ko) 1991-12-19
NO178401B (no) 1995-12-11
GB2244487A (en) 1991-12-04
FI912563A (fi) 1991-11-30
YU47812B (sr) 1996-01-09
NZ238288A (en) 1993-07-27
HUT61311A (en) 1992-12-28
JPH0597855A (ja) 1993-04-20
GB2244487B (en) 1994-02-02
AP9100266A0 (en) 1991-07-31
RO109542B1 (ro) 1995-03-30
AU7734891A (en) 1991-12-05
IE911818A1 (en) 1991-12-04
AU642494B2 (en) 1993-10-21
HU911789D0 (en) 1991-12-30
US5270311A (en) 1993-12-14
GB9111132D0 (en) 1991-07-17
AP248A (en) 1993-03-16
YU94791A (sh) 1994-06-24
IL98316A0 (en) 1992-06-21
EP0459702A1 (en) 1991-12-04
NO912051D0 (no) 1991-05-28
OA09358A (fr) 1992-09-15
CA2043424A1 (en) 1991-11-30
CS159591A3 (en) 1992-01-15
JP2504879B2 (ja) 1996-06-05
CN1056879A (zh) 1991-12-11
NO912051L (no) 1991-12-02
PT97776A (pt) 1992-03-31
IL98316A (en) 1995-05-26

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Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: ZENECA LIMITED

FD Application lapsed