FI911083A - Menetelmä kolinergisina aineina käyttökelpoisten 1-atsabisyklo/2.2.1/heptaani- tai -/2.2.2/oktaani-3-oni-O-oksiimien valmistamiseksi - Google Patents
Menetelmä kolinergisina aineina käyttökelpoisten 1-atsabisyklo/2.2.1/heptaani- tai -/2.2.2/oktaani-3-oni-O-oksiimien valmistamiseksi Download PDFInfo
- Publication number
- FI911083A FI911083A FI911083A FI911083A FI911083A FI 911083 A FI911083 A FI 911083A FI 911083 A FI911083 A FI 911083A FI 911083 A FI911083 A FI 911083A FI 911083 A FI911083 A FI 911083A
- Authority
- FI
- Finland
- Prior art keywords
- azabicyclo
- oximes
- octan
- heptane
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI943029A FI114472B (fi) | 1990-03-06 | 1994-06-22 | Menetelmä kolinergisina aineina käyttökelpoisten atsabisyklo- ja atsasyklo-oksiimien valmistamiseksi |
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48891690A | 1990-03-06 | 1990-03-06 | |
| US48891690 | 1990-03-06 | ||
| US59164790A | 1990-10-02 | 1990-10-02 | |
| US59164790 | 1990-10-02 | ||
| US64147891A | 1991-01-22 | 1991-01-22 | |
| US64147891 | 1991-01-22 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI911083A0 FI911083A0 (fi) | 1991-03-04 |
| FI911083A true FI911083A (fi) | 1991-09-07 |
| FI95705B FI95705B (fi) | 1995-11-30 |
| FI95705C FI95705C (fi) | 1996-03-11 |
Family
ID=27413829
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI911083A FI95705C (fi) | 1990-03-06 | 1991-03-04 | Menetelmä kolinergisina aineina käyttökelpoisten 1-atsabisyklo/2.2.1/heptaani- tai -/2.2.2/oktaani-3-oni-O-oksiimien valmistamiseksi |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0445731B1 (fi) |
| JP (3) | JP3223192B2 (fi) |
| KR (1) | KR0182268B1 (fi) |
| CN (1) | CN1054601A (fi) |
| AT (1) | ATE132868T1 (fi) |
| AU (1) | AU630542B2 (fi) |
| CA (1) | CA2037541C (fi) |
| DE (1) | DE69116185T2 (fi) |
| DK (1) | DK0445731T3 (fi) |
| ES (1) | ES2082024T3 (fi) |
| FI (1) | FI95705C (fi) |
| GR (1) | GR3019226T3 (fi) |
| HK (1) | HK1005025A1 (fi) |
| HU (1) | HUT57210A (fi) |
| IE (1) | IE70322B1 (fi) |
| IL (1) | IL97266A0 (fi) |
| NO (1) | NO177711C (fi) |
| NZ (1) | NZ237300A (fi) |
| PT (1) | PT96946B (fi) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5306718A (en) * | 1990-03-06 | 1994-04-26 | Warner-Lambert Company | Oxime and amine substituted azabicyclo and azocyclo muscarinic agonists and methods of treatment |
| US5276184A (en) * | 1990-08-03 | 1994-01-04 | The Dow Chemical Company | Sulfonamide compounds containing mesogenic moieties |
| US5262509A (en) * | 1990-08-03 | 1993-11-16 | The Dow Chemical Company | Mesogenic glycidyl amines |
| US5268434A (en) * | 1990-08-03 | 1993-12-07 | The Dow Chemical Company | Diamino-alpha-alkylstilbenes as epoxy resin curing agents |
| US5296570A (en) * | 1990-08-03 | 1994-03-22 | The Dow Chemical Company | Curable mixtures of mesogenic epoxy resins and mesogenic polyamines and cured compositions |
| US5391651A (en) * | 1990-08-03 | 1995-02-21 | The Dow Chemical Company | Curable mixtures of mesogenic epoxy resins and mesogenic polyamines and cured compositions |
| US5414125A (en) * | 1990-08-03 | 1995-05-09 | The Dow Chemical Company | Diamino-alpha-alkylstilbenes |
| US5264502A (en) * | 1990-08-03 | 1993-11-23 | The Dow Chemical Company | Diamino-alpha-alkylstilbene curing agents for epoxy resins |
| GB2258652A (en) * | 1991-08-15 | 1993-02-17 | Merck Sharp & Dohme | Pharmaceutically useful azabicyclic oxime ethers |
| WO1993008191A1 (en) * | 1991-10-15 | 1993-04-29 | Warner-Lambert Company | Azabicyclo oxime and amine cholinergic agents and methods of treatment |
| ZA931109B (en) * | 1992-03-04 | 1993-09-22 | Akzo Nv | Tetrahydropyrimidine derivatives. |
| US5298575A (en) * | 1992-11-30 | 1994-03-29 | The Dow Chemical Company | Nitro group terminated mesogenic epoxy resin adducts |
| US5552407A (en) * | 1993-06-11 | 1996-09-03 | New York University Medical Center | Anhydroecgonine compounds and their use as anticholinergic agents |
| US5514812A (en) * | 1994-06-10 | 1996-05-07 | Warner-Lambert Company | Preparation of stereochemically pure oximes with muscarinic activity |
| US5897875A (en) * | 1995-12-20 | 1999-04-27 | Pein; Eckhart | Use of α,α-diphenylacetic acid-4-(N-methyl-piperidyl) ester as a spasmolytic analgesic |
| NZ335784A (en) * | 1997-01-27 | 2000-12-22 | Warner Lambert Co | Process for isolation of (z)-azabicyclo oxime ethers by reacting an O-substituted hydroxylamine with an azabicycloketone |
| US5733912A (en) * | 1997-02-19 | 1998-03-31 | Abbott Laboratories | 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission |
| AU2206599A (en) * | 1997-12-23 | 1999-07-12 | Alcon Laboratories, Inc. | Oximino-piperidine, -pyrrolidine and -azepine derivatives, their preparation andtheir use as muscarinic receptor (ant-)agonists |
| JP2003508412A (ja) * | 1999-08-27 | 2003-03-04 | アベンティス・クロップサイエンス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 農薬としてのアザビシクロおよびアザシクロオキシム、並びにアミン化合物 |
| KR100465277B1 (ko) * | 2002-01-24 | 2005-01-13 | 한국과학기술연구원 | 신규한 옥심계 아자 두 고리 화합물 및 그 제조방법 |
| DE10302912A1 (de) * | 2003-01-24 | 2004-08-12 | Bayer Faser Gmbh | Chlorbeständige Elastanfasern |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2019536A1 (de) * | 1970-04-23 | 1971-11-11 | Basf Ag | Oximcarbamate |
| DE2552176A1 (de) * | 1975-11-21 | 1977-06-02 | Hoechst Ag | Neue piperidin-derivate, ihre herstellung und verwendung |
| US4353922A (en) * | 1981-03-13 | 1982-10-12 | Syntex (U.S.A.) Inc. | Anticholinergic bronchodilators |
-
1991
- 1991-02-18 IL IL97266A patent/IL97266A0/xx unknown
- 1991-03-04 NZ NZ237300A patent/NZ237300A/xx unknown
- 1991-03-04 AU AU72602/91A patent/AU630542B2/en not_active Ceased
- 1991-03-04 FI FI911083A patent/FI95705C/fi not_active IP Right Cessation
- 1991-03-05 CA CA002037541A patent/CA2037541C/en not_active Expired - Fee Related
- 1991-03-05 NO NO910860A patent/NO177711C/no not_active IP Right Cessation
- 1991-03-05 AT AT91103308T patent/ATE132868T1/de not_active IP Right Cessation
- 1991-03-05 EP EP91103308A patent/EP0445731B1/en not_active Expired - Lifetime
- 1991-03-05 ES ES91103308T patent/ES2082024T3/es not_active Expired - Lifetime
- 1991-03-05 JP JP06239891A patent/JP3223192B2/ja not_active Expired - Fee Related
- 1991-03-05 DK DK91103308.2T patent/DK0445731T3/da active
- 1991-03-05 KR KR1019910003542A patent/KR0182268B1/ko not_active IP Right Cessation
- 1991-03-05 HU HU91712A patent/HUT57210A/hu unknown
- 1991-03-05 DE DE69116185T patent/DE69116185T2/de not_active Expired - Fee Related
- 1991-03-05 IE IE73191A patent/IE70322B1/en not_active IP Right Cessation
- 1991-03-06 PT PT96946A patent/PT96946B/pt active IP Right Revival
- 1991-03-06 CN CN91101359A patent/CN1054601A/zh active Pending
-
1996
- 1996-03-06 GR GR960400634T patent/GR3019226T3/el unknown
-
1998
- 1998-05-14 HK HK98104172A patent/HK1005025A1/xx not_active IP Right Cessation
-
2000
- 2000-02-01 JP JP2000023520A patent/JP2000212163A/ja active Pending
- 2000-02-01 JP JP2000023519A patent/JP2000239166A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0445731B1 (en) | 1996-01-10 |
| KR0182268B1 (ko) | 1999-05-01 |
| HU910712D0 (en) | 1991-09-30 |
| ES2082024T3 (es) | 1996-03-16 |
| NO177711B (no) | 1995-07-31 |
| KR910016728A (ko) | 1991-11-05 |
| CA2037541A1 (en) | 1992-08-11 |
| JP2000239166A (ja) | 2000-09-05 |
| CA2037541C (en) | 2001-10-02 |
| FI911083A0 (fi) | 1991-03-04 |
| AU630542B2 (en) | 1992-10-29 |
| FI95705C (fi) | 1996-03-11 |
| IL97266A0 (en) | 1992-05-25 |
| NO910860L (no) | 1991-09-09 |
| NO177711C (no) | 1995-11-08 |
| JPH04217660A (ja) | 1992-08-07 |
| JP3223192B2 (ja) | 2001-10-29 |
| DE69116185T2 (de) | 1996-05-15 |
| JP2000212163A (ja) | 2000-08-02 |
| FI95705B (fi) | 1995-11-30 |
| NZ237300A (en) | 1993-12-23 |
| PT96946A (pt) | 1991-10-31 |
| IE910731A1 (en) | 1991-09-11 |
| NO910860D0 (no) | 1991-03-05 |
| CN1054601A (zh) | 1991-09-18 |
| PT96946B (pt) | 1998-07-31 |
| IE70322B1 (en) | 1996-11-13 |
| ATE132868T1 (de) | 1996-01-15 |
| HK1005025A1 (en) | 1998-12-18 |
| GR3019226T3 (en) | 1996-06-30 |
| DK0445731T3 (da) | 1996-04-29 |
| DE69116185D1 (de) | 1996-02-22 |
| EP0445731A1 (en) | 1991-09-11 |
| AU7260291A (en) | 1991-09-12 |
| HUT57210A (en) | 1991-11-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB | Publication of examined application | ||
| MA | Patent expired |