FI91067C - Alkaloididimeerien valmistus käyttäen ferri-ionia - Google Patents

Alkaloididimeerien valmistus käyttäen ferri-ionia

Info

Publication number
FI91067C
FI91067C FI882236A FI882236A FI91067C FI 91067 C FI91067 C FI 91067C FI 882236 A FI882236 A FI 882236A FI 882236 A FI882236 A FI 882236A FI 91067 C FI91067 C FI 91067C
Authority
FI
Finland
Prior art keywords
preparation
ferric ions
alkaloid
dimers
alkaloid dimers
Prior art date
Application number
FI882236A
Other languages
English (en)
Swedish (sv)
Other versions
FI882236A (fi
FI882236A0 (fi
FI91067B (fi
Inventor
Anne Elizabeth Goodbody
John Vukovic
Original Assignee
Mitsui Petrochemical Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Petrochemical Ind filed Critical Mitsui Petrochemical Ind
Publication of FI882236A publication Critical patent/FI882236A/fi
Publication of FI882236A0 publication Critical patent/FI882236A0/fi
Application granted granted Critical
Publication of FI91067B publication Critical patent/FI91067B/fi
Publication of FI91067C publication Critical patent/FI91067C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FI882236A 1986-09-18 1988-05-12 Alkaloididimeerien valmistus käyttäen ferri-ionia FI91067C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/908,991 US4778885A (en) 1986-09-18 1986-09-18 Production of alkaloid dimers using ferric ion
US90899186 1986-09-18
JP8700682 1987-09-16
PCT/JP1987/000682 WO1988002002A1 (en) 1986-09-18 1987-09-16 Production of alkaloid dimers using ferric ion

Publications (4)

Publication Number Publication Date
FI882236A FI882236A (fi) 1988-05-12
FI882236A0 FI882236A0 (fi) 1988-05-12
FI91067B FI91067B (fi) 1994-01-31
FI91067C true FI91067C (fi) 1994-05-10

Family

ID=25426478

Family Applications (1)

Application Number Title Priority Date Filing Date
FI882236A FI91067C (fi) 1986-09-18 1988-05-12 Alkaloididimeerien valmistus käyttäen ferri-ionia

Country Status (8)

Country Link
US (1) US4778885A (fi)
EP (1) EP0282602B1 (fi)
JP (1) JP2502332B2 (fi)
KR (1) KR950010087B1 (fi)
CA (1) CA1303036C (fi)
DE (1) DE3774697D1 (fi)
FI (1) FI91067C (fi)
WO (1) WO1988002002A1 (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047528A (en) * 1987-01-22 1991-09-10 University Of Bristish Columbia Process of synthesis of vinblastine and vincristine
USRE37449E1 (en) 1987-02-06 2001-11-13 University Of British Columbia Process of synthesis of 3′,4′-anhydrovinblastine, vinblastine and vincristine
FI80462C (fi) * 1988-06-10 1990-06-11 Huhtamaeki Oy Foerfarande foer framstaellning av dimera catharanthus-alkaloider.
JP2582131B2 (ja) * 1988-08-11 1997-02-19 三井石油化学工業株式会社 二量体アルカロイドの製造方法
US5037977A (en) * 1988-08-11 1991-08-06 Mitsui Petrochemical Industries Ltd. Method for production of dimeric alkaloids
US6011041A (en) * 1995-07-28 2000-01-04 University Of British Columbia Use of anhydrovinblastine
US20030162803A1 (en) * 1997-03-04 2003-08-28 Bruce Schmidt Anhydrovinblastine for the treatment of cancer
CA2219095A1 (en) * 1997-03-04 1998-09-04 Bruce Schmidt Anhydrovinblastine for the treatment of cervical and lung cancer
AU783029B2 (en) * 1997-03-04 2005-09-15 University Of British Columbia, The Anhydrovinblastine for the treatment of cervical and lung cancer
AR024852A1 (es) * 2000-01-12 2002-10-30 Eriochem Sa Procedimiento para la produccion de ditartrato de 5'-nor-anhidrovinblastina a partir de especies vegetales del genero catharanthus y procedimiento a escala industrial.
CN103936769B (zh) * 2014-04-30 2016-10-05 淮海工学院 一种制备高光学纯脱水长春碱的方法
CN106749342B (zh) * 2016-11-09 2017-12-19 新乡学院 一种长春碱衍生物的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3225030A (en) * 1965-02-15 1965-12-21 Lilly Co Eli Method of preparing leurosine and vincaleukoblastine
US3422112A (en) * 1968-01-22 1969-01-14 Lilly Co Eli Indolyl vindolines
FR2296418B1 (fi) * 1974-12-30 1978-07-21 Anvar
US4279817A (en) * 1975-05-30 1981-07-21 The United States Of America As Represented By The Department Of Health & Human Services Method for producing dimer alkaloids
GB1551054A (en) * 1976-03-04 1979-08-22 Atta Ur Rahman Syntheses of vinblastine vincristine and vinrosidine
HU178084B (en) * 1977-05-31 1982-03-28 Richter Gedeon Vegyeszet New process for the extraction of native vindoline,catharantine,3',4'-anhydrovinblastine,leurosine and,if desired,of other diinodle alkaloids from vinca rosea l.drogue
FR2443470A1 (fr) * 1978-12-08 1980-07-04 Anvar Nouveau procede de synthese de la vinblastine et de la leurosidine

Also Published As

Publication number Publication date
FI882236A (fi) 1988-05-12
JP2502332B2 (ja) 1996-05-29
DE3774697D1 (de) 1992-01-02
FI882236A0 (fi) 1988-05-12
EP0282602A1 (en) 1988-09-21
WO1988002002A1 (en) 1988-03-24
EP0282602B1 (en) 1991-11-21
KR950010087B1 (ko) 1995-09-06
CA1303036C (en) 1992-06-09
JPH01500830A (ja) 1989-03-23
KR880701720A (ko) 1988-11-04
FI91067B (fi) 1994-01-31
US4778885A (en) 1988-10-18

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Legal Events

Date Code Title Description
BB Publication of examined application
TC Name/ company changed in patent

Owner name: MITSUI CHEMICALS, INC.

MM Patent lapsed

Owner name: MITSUI CHEMICALS, INC.