FI906212A0 - Inhibitorer foer hiv-proteas, vilka aer anvaendbara vid av aids. - Google Patents

Inhibitorer foer hiv-proteas, vilka aer anvaendbara vid av aids.

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Publication number
FI906212A0
FI906212A0 FI906212A FI906212A FI906212A0 FI 906212 A0 FI906212 A0 FI 906212A0 FI 906212 A FI906212 A FI 906212A FI 906212 A FI906212 A FI 906212A FI 906212 A0 FI906212 A0 FI 906212A0
Authority
FI
Finland
Prior art keywords
inhibitorer
proteas
foer
hiv
aids
Prior art date
Application number
FI906212A
Other languages
English (en)
Other versions
FI906212A (fi
Inventor
Wayne J Thompson
Joel R Huff
Steven D Young
Joseph P Vacca
Terry A Lyle
Randall W Hungate
Arun K Ghosh
Susan F Britcher
Original Assignee
Merck & Co Inc
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Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of FI906212A0 publication Critical patent/FI906212A0/fi
Publication of FI906212A publication Critical patent/FI906212A/fi

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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
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    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
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    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
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  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
FI906212A 1989-12-18 1990-12-17 Inhibitorer foer hiv-proteas, vilka aer anvaendbara vid av aids. FI906212A (fi)

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US45291289A 1989-12-18 1989-12-18
US59728690A 1990-10-15 1990-10-15
US61965490A 1990-12-04 1990-12-04

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CN (1) CN1053607A (fi)
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NO905428L (no) 1991-06-19
JPH05345775A (ja) 1993-12-27
KR910011818A (ko) 1991-08-07
EP0434365A3 (en) 1991-11-27
HU908295D0 (en) 1991-06-28
CA2032259A1 (en) 1991-06-19
IE904555A1 (en) 1991-06-19
FI906212A (fi) 1991-06-19
NO905428D0 (no) 1990-12-17
IL96691A0 (en) 1991-09-16
PT96234A (pt) 1991-10-15
CN1053607A (zh) 1991-08-07
EP0434365A2 (en) 1991-06-26
AU6822990A (en) 1991-06-27

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