FI903215A0 - Heteroarylamino- och heteroaryloxipyridinaminer och till desa hoerande foereningar, foerfarande foer deras framstaellning samt deras anvaendning som laekemedel. - Google Patents
Heteroarylamino- och heteroaryloxipyridinaminer och till desa hoerande foereningar, foerfarande foer deras framstaellning samt deras anvaendning som laekemedel.Info
- Publication number
- FI903215A0 FI903215A0 FI903215A FI903215A FI903215A0 FI 903215 A0 FI903215 A0 FI 903215A0 FI 903215 A FI903215 A FI 903215A FI 903215 A FI903215 A FI 903215A FI 903215 A0 FI903215 A0 FI 903215A0
- Authority
- FI
- Finland
- Prior art keywords
- och
- deras
- hoerande
- heteroaryloxipyridinaminer
- foereningar
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dermatology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Tires In General (AREA)
- Photoreceptors In Electrophotography (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/372,509 US4970219A (en) | 1989-06-28 | 1989-06-28 | Heteroarylamino- and heteroaryloxypyridinamine compounds which have useful utility in treating skin disorders |
| US07/496,723 US4983615A (en) | 1989-06-28 | 1990-03-21 | Heteroarylamino- and heteroaryloxypyridinamine compounds which are useful in treating skin disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI903215A0 true FI903215A0 (fi) | 1990-06-26 |
Family
ID=27005797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI903215A FI903215A0 (fi) | 1989-06-28 | 1990-06-26 | Heteroarylamino- och heteroaryloxipyridinaminer och till desa hoerande foereningar, foerfarande foer deras framstaellning samt deras anvaendning som laekemedel. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4983615A (fi) |
| EP (1) | EP0405425B1 (fi) |
| JP (1) | JPH0776212B2 (fi) |
| KR (1) | KR0162644B1 (fi) |
| AT (1) | ATE169622T1 (fi) |
| AU (1) | AU634553B2 (fi) |
| CA (1) | CA2019957C (fi) |
| DE (1) | DE69032550T2 (fi) |
| DK (1) | DK0405425T3 (fi) |
| ES (1) | ES2120404T3 (fi) |
| FI (1) | FI903215A0 (fi) |
| IE (1) | IE902329A1 (fi) |
| IL (1) | IL94877A (fi) |
| NO (1) | NO902862L (fi) |
| NZ (1) | NZ234249A (fi) |
| PT (1) | PT94503B (fi) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5006537A (en) * | 1989-08-02 | 1991-04-09 | Hoechst-Roussel Pharmaceuticals, Inc. | 1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones |
| DE69016531T2 (de) * | 1989-08-02 | 1995-07-06 | Hoechst Roussel Pharma | 2,3-Dihydro-1-(pyridinylamino)-indole, Verfahren zu ihrer Herstellung und ihre Anwendung als Arzneimittel. |
| US5037835A (en) * | 1989-10-24 | 1991-08-06 | Hoechst-Roussel Pharmaceuticals Inc. | Benzocycloalkylaminopyridinamines and related compounds as topical antiinflammatory agents for the treatment of skin disorders |
| US5102891A (en) * | 1990-07-23 | 1992-04-07 | Hoechst-Roussel Pharmaceuticals Inc. | 1-(substituted pyridinylamino)-1H-indol-5-yl substituted carbamates |
| US5177088A (en) * | 1991-04-17 | 1993-01-05 | Hoechst-Roussel Pharmaceuticals Incorporated | Substituted 3-(pyridinylamino)-indoles |
| US5185350A (en) * | 1991-09-23 | 1993-02-09 | Hoechst-Roussel Pharmaceuticals Incorporated | Substituted pyridinylamino-1h-indoles,1h-indazoles,2h-indazoles, benzo (b)thiophenes and 1,2-benzisothiazoles |
| BR9206810A (pt) * | 1991-11-25 | 1995-10-31 | Pfizer | Derivados de indol |
| US6756367B2 (en) | 1998-02-03 | 2004-06-29 | Novartis Ag | Benzo-oxadiazoles, -thiadiazoles and -1,4-diazines, pharmaceutical compositions containing them and a process for preparing them |
| US6455554B1 (en) | 1999-06-07 | 2002-09-24 | Targacept, Inc. | Oxopyridinyl pharmaceutical compositions and methods for use |
| DE10006139A1 (de) * | 2000-02-11 | 2001-08-16 | Merck Patent Gmbh | Indol-3-yl-Derivate |
| AU2001277621A1 (en) * | 2000-08-09 | 2002-03-04 | Astrazeneca Ab | Antiangiogenic bicyclic derivatives |
| TWI304061B (en) | 2000-10-20 | 2008-12-11 | Eisai R&D Man Co Ltd | Nitrogen-containing aromatic ring derivatives |
| JP2003233264A (ja) * | 2002-02-12 | 2003-08-22 | Canon Inc | 定着装置 |
| US7994159B2 (en) | 2003-03-10 | 2011-08-09 | Eisai R&D Management Co., Ltd. | c-Kit kinase inhibitor |
| JP4303726B2 (ja) | 2003-11-11 | 2009-07-29 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ウレア誘導体およびその製造方法 |
| JP2005242333A (ja) * | 2004-01-30 | 2005-09-08 | Canon Inc | 可撓性スリーブを有する像加熱装置 |
| JP4594125B2 (ja) | 2004-02-20 | 2010-12-08 | キヤノン株式会社 | 画像定着装置 |
| JP2005316443A (ja) * | 2004-03-30 | 2005-11-10 | Canon Inc | 像加熱装置及びこの装置に用いられる搬送ローラ |
| JP4280664B2 (ja) * | 2004-03-31 | 2009-06-17 | キヤノン株式会社 | 像加熱装置 |
| DE602005013990D1 (de) | 2004-09-17 | 2009-05-28 | Eisai R&D Man Co Ltd | Medizinische zusammensetzung mit verbesserter stabilität und reduzierten gelierungseigenschaften |
| US9006240B2 (en) | 2005-08-02 | 2015-04-14 | Eisai R&D Management Co., Ltd. | Method for assay on the effect of vascularization inhibitor |
| US20090209580A1 (en) | 2006-05-18 | 2009-08-20 | Eisai R & D Management Co., Ltd. | Antitumor agent for thyroid cancer |
| US8865737B2 (en) | 2006-08-28 | 2014-10-21 | Eisai R&D Management Co., Ltd. | Antitumor agent for undifferentiated gastric cancer |
| CN101600694A (zh) | 2007-01-29 | 2009-12-09 | 卫材R&D管理有限公司 | 未分化型胃癌治疗用组合物 |
| EP2218712B1 (en) | 2007-11-09 | 2015-07-01 | Eisai R&D Management Co., Ltd. | Combination of anti-angiogenic substance and anti-tumor platinum complex |
| MX2012014776A (es) | 2010-06-25 | 2013-01-29 | Eisai R&D Man Co Ltd | Agente antitumoral que emplea compuestos con efecto inhibidor de cinasas combinados. |
| CA2828946C (en) | 2011-04-18 | 2016-06-21 | Eisai R&D Management Co., Ltd. | Therapeutic agent for tumor |
| ES2841809T3 (es) | 2011-06-03 | 2021-07-09 | Eisai R&D Man Co Ltd | Biomarcadores para pronosticar y evaluar el grado de respuesta de sujetos con cáncer de tiroides y de riñón a compuestos de lenvatinib |
| KR20150098605A (ko) | 2012-12-21 | 2015-08-28 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 퀴놀린 유도체의 비정질 형태 및 그의 제조방법 |
| ES2687968T3 (es) | 2013-05-14 | 2018-10-30 | Eisai R&D Management Co., Ltd. | Biomarcadores para pronosticar y evaluar la reactividad de sujetos con cáncer de endometrio a compuestos con lenvatinib |
| KR102512940B1 (ko) | 2014-08-28 | 2023-03-23 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 고순도의 퀴놀린 유도체 및 이를 제조하는 방법 |
| CA2976325C (en) | 2015-02-25 | 2023-07-04 | Eisai R&D Management Co., Ltd. | Method for suppressing bitterness of quinoline derivative |
| KR102662228B1 (ko) | 2015-03-04 | 2024-05-02 | 머크 샤프 앤드 돔 코포레이션 | 암을 치료하기 위한 pd-1 길항제 및 vegfr/fgfr/ret 티로신 키나제 억제제의 조합 |
| BR112017027227B1 (pt) | 2015-06-16 | 2023-12-12 | Eisai R&D Management Co., Ltd | Agente anti-câncer |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3118884A (en) * | 1959-10-19 | 1964-01-21 | Schering Corp | Derivatives of 3-azaphenothiazine and 3-azaphenoxazine |
| US3495969A (en) * | 1967-09-25 | 1970-02-17 | Mobil Oil Corp | Substituted nitropyridines as herbicides |
| AT294090B (de) * | 1969-04-22 | 1971-11-10 | Degussa | Verfahren zur Herstellung von neuen Aminopyridinen, von deren optisch aktiven bzw. diastereomeren Formen, deren Salzen und deren quartären Verbindungen |
| US3576616A (en) * | 1969-05-15 | 1971-04-27 | Monsanto Co | Herbicidal compositions and methods |
| US3721676A (en) * | 1969-11-12 | 1973-03-20 | Merck & Co Inc | Certain 3-amino-2(1h)pyridones |
| SE422799B (sv) * | 1975-05-28 | 1982-03-29 | Merck & Co Inc | Analogiforfarande for framstellning av 1,3-dihydroimidazo (4,5-b)pyridin-2-oner |
| GB2073736B (en) * | 1979-10-03 | 1984-02-01 | Ici Ltd | Process for preparing pyridinyloxyphenoxy compounds and derivatives thereof |
| IE56702B1 (en) * | 1982-12-01 | 1991-11-06 | Usv Pharma Corp | Antiinflammatory antiallergic compounds |
| DE3608089A1 (de) * | 1986-03-08 | 1987-09-10 | Schering Ag | Heteroaryl-oxy-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel |
| ATE115143T1 (de) * | 1987-04-24 | 1994-12-15 | Hoechst Roussel Pharma | N-(pyridinyl)-1h-indol-1-amine, verfahren zu deren herstellung und ihre verwendung als arzneimittel. |
| US4806554A (en) * | 1988-01-11 | 1989-02-21 | Hoechst-Roussel Pharmaceuticals, Inc. | Pyrazol and indazolpyridinamines |
-
1990
- 1990-03-21 US US07/496,723 patent/US4983615A/en not_active Expired - Fee Related
- 1990-06-26 DK DK90112086T patent/DK0405425T3/da active
- 1990-06-26 KR KR1019900009442A patent/KR0162644B1/ko not_active IP Right Cessation
- 1990-06-26 FI FI903215A patent/FI903215A0/fi not_active Application Discontinuation
- 1990-06-26 NZ NZ234249A patent/NZ234249A/xx unknown
- 1990-06-26 IL IL9487790A patent/IL94877A/en not_active IP Right Cessation
- 1990-06-26 DE DE69032550T patent/DE69032550T2/de not_active Expired - Fee Related
- 1990-06-26 AT AT90112086T patent/ATE169622T1/de not_active IP Right Cessation
- 1990-06-26 ES ES90112086T patent/ES2120404T3/es not_active Expired - Lifetime
- 1990-06-26 EP EP90112086A patent/EP0405425B1/en not_active Expired - Lifetime
- 1990-06-27 CA CA002019957A patent/CA2019957C/en not_active Expired - Fee Related
- 1990-06-27 IE IE232990A patent/IE902329A1/en not_active IP Right Cessation
- 1990-06-27 NO NO90902862A patent/NO902862L/no unknown
- 1990-06-27 JP JP2166945A patent/JPH0776212B2/ja not_active Expired - Lifetime
- 1990-06-27 AU AU57846/90A patent/AU634553B2/en not_active Ceased
- 1990-06-27 PT PT94503A patent/PT94503B/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL94877A (en) | 1995-05-26 |
| NO902862L (no) | 1991-01-02 |
| EP0405425A2 (en) | 1991-01-02 |
| CA2019957A1 (en) | 1990-12-28 |
| AU634553B2 (en) | 1993-02-25 |
| ES2120404T3 (es) | 1998-11-01 |
| EP0405425B1 (en) | 1998-08-12 |
| JPH0776212B2 (ja) | 1995-08-16 |
| ATE169622T1 (de) | 1998-08-15 |
| DE69032550D1 (de) | 1998-09-17 |
| EP0405425A3 (en) | 1992-09-09 |
| KR910000707A (ko) | 1991-01-30 |
| NO902862D0 (no) | 1990-06-27 |
| PT94503B (pt) | 1997-02-28 |
| JPH03115263A (ja) | 1991-05-16 |
| IE902329A1 (en) | 1991-01-16 |
| CA2019957C (en) | 2001-06-12 |
| NZ234249A (en) | 1993-08-26 |
| DE69032550T2 (de) | 1999-02-18 |
| IE902329L (en) | 1990-12-28 |
| US4983615A (en) | 1991-01-08 |
| PT94503A (pt) | 1991-02-08 |
| AU5784690A (en) | 1991-01-03 |
| DK0405425T3 (da) | 1999-05-17 |
| KR0162644B1 (ko) | 1998-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Application withdrawn |
Owner name: HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED |