FI900217A0 - Menetelmä terapeuttisesti aktiivisten 11 -fenyyli-4,9,15-estratrieenien valmistamiseksi - Google Patents
Menetelmä terapeuttisesti aktiivisten 11 -fenyyli-4,9,15-estratrieenien valmistamiseksiInfo
- Publication number
- FI900217A0 FI900217A0 FI900217A FI900217A FI900217A0 FI 900217 A0 FI900217 A0 FI 900217A0 FI 900217 A FI900217 A FI 900217A FI 900217 A FI900217 A FI 900217A FI 900217 A0 FI900217 A0 FI 900217A0
- Authority
- FI
- Finland
- Prior art keywords
- implies
- pct
- carbon atoms
- hydrogen atom
- case
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
- C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0096—Alkynyl derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19873723788 DE3723788A1 (de) | 1987-07-16 | 1987-07-16 | 11(beta)-phenyl-4,9,15-estratriene, deren herstellung und diese enthaltende pharmazeutische praeparate |
DE3723788 | 1987-07-16 | ||
DE8800447 | 1988-07-15 | ||
PCT/DE1988/000447 WO1989000578A1 (en) | 1987-07-16 | 1988-07-15 | 11beta-PHENYL-4,9,15-ESTRATRIENES, THEIR MANUFACTURE, AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM |
Publications (3)
Publication Number | Publication Date |
---|---|
FI900217A0 true FI900217A0 (fi) | 1990-01-15 |
FI94349B FI94349B (fi) | 1995-05-15 |
FI94349C FI94349C (fi) | 1995-08-25 |
Family
ID=6331846
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI900217A FI94349C (fi) | 1987-07-16 | 1990-01-15 | Menetelmä terapeuttisesti aktiivisten 11 -fenyyli-4,9,15-estratrieenien valmistamiseksi |
Country Status (12)
Country | Link |
---|---|
US (1) | US5132299A (fi) |
EP (1) | EP0299913B1 (fi) |
JP (1) | JP2792876B2 (fi) |
AT (1) | ATE87631T1 (fi) |
CA (1) | CA1320946C (fi) |
DD (1) | DD281809A5 (fi) |
DE (2) | DE3723788A1 (fi) |
DK (1) | DK43189A (fi) |
ES (1) | ES2054859T3 (fi) |
FI (1) | FI94349C (fi) |
HU (1) | HU203764B (fi) |
WO (1) | WO1989000578A1 (fi) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3917274A1 (de) * | 1989-05-24 | 1990-11-29 | Schering Ag | 9(alpha)-hydroxy-19, 11(beta)-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate |
EP0411733B1 (de) * | 1989-08-04 | 1998-10-21 | Schering Aktiengesellschaft | 11 Beta-Aryl-gona-4,9-dien-3-one |
DE4042004A1 (de) * | 1990-12-22 | 1992-06-25 | Schering Ag | 14(beta)-h-, 14- u. 15-en-11(beta)-aryl-4-estrene |
US5407928A (en) * | 1990-08-15 | 1995-04-18 | Schering Aktiengesellschaft | 11β-aryl-gona-4,9-dien-3-ones |
US5639598A (en) * | 1994-05-19 | 1997-06-17 | The Trustees Of The University Of Pennsylvania | Method and kit for identification of antiviral agents capable of abrogating HIV Vpr-Rip-1 binding interactions |
US5780220A (en) * | 1994-05-19 | 1998-07-14 | Trustees Of The University Of Pennsylvania | Methods and compositions for inhibiting HIV replication |
US5767113A (en) * | 1995-05-10 | 1998-06-16 | The Salk Institute For Biological Studies | Compounds useful for concurrently activating glucocorticoid-induced response and reducing multidrug resistance |
DE19706061A1 (de) * | 1997-02-07 | 1998-08-13 | Schering Ag | Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette |
US6090798A (en) * | 1997-12-19 | 2000-07-18 | Alcon Laboratories, Inc. | Treatment of GLC1A glaucoma with glucocorticoid antagonists |
DE102004059880A1 (de) * | 2004-12-10 | 2006-06-14 | Grünenthal GmbH | Stabiles, hormonhaltiges (Zwischen-)Produkt |
WO2011150209A1 (en) | 2010-05-26 | 2011-12-01 | Corcept Therapeutics, Inc. | Treatment of muscular dystrophy |
WO2016140867A1 (en) | 2015-03-02 | 2016-09-09 | Corcept Therapeutics, Inc. | Use of glucocorticoid receptor antagonist and somatostatin analogues to treat acth-secreting tumors |
CA2978960C (en) | 2015-03-30 | 2023-05-02 | Corcept Therapeutics, Inc. | Use of glucocorticoid receptor antagonists in combination with glucocorticoids to treat adrenal insufficiency |
ES2865334T3 (es) | 2015-08-13 | 2021-10-15 | Corcept Therapeutics Inc | Método de diagnóstico diferencial de síndrome de Cushing dependiente de ACTH |
SG11201806101SA (en) | 2016-01-19 | 2018-08-30 | Corcept Therapeutics Inc | Differential diagnosis of ectopic cushing's syndrome |
MX2019011543A (es) | 2017-03-31 | 2019-12-16 | Corcept Therapeutics Inc | Moduladores del receptor de glucocorticoides para el tratamiento de cancer cervical. |
CA3065555A1 (en) | 2017-06-20 | 2018-12-27 | Corcept Therapeutics, Inc. | Methods of treating neuroepithelial tumors using selective glucocorticoid receptor modulators |
EP3713086A1 (de) | 2019-03-18 | 2020-09-23 | Siemens Aktiengesellschaft | Schutzschaltung für einen halbleiterschalter |
JP2024500748A (ja) | 2020-12-18 | 2024-01-10 | インスティル バイオ (ユーケイ) リミテッド | 腫瘍浸潤リンパ球の処理 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2530817A (en) * | 1948-05-19 | 1950-11-21 | Univ Pennsylvania | 13-monomethyl steroids |
US2940968A (en) * | 1958-10-01 | 1960-06-14 | Merck & Co Inc | Dimethylated steroids and processes for producing same |
CH558346A (de) * | 1971-06-17 | 1975-01-31 | Sandoz Ag | Verfahren zur herstellung neuer 3-oximino-17(alpha)-propadienyl-substituierter steroide. |
DE3042529A1 (de) * | 1980-11-07 | 1982-06-24 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | 11-methylen- (delta)(pfeil hoch)1(pfeil hoch)(pfeil hoch)5(pfeil hoch) -steroide, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
FR2522328B1 (fr) * | 1982-03-01 | 1986-02-14 | Roussel Uclaf | Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments |
EP0116974B1 (de) * | 1983-02-18 | 1986-10-29 | Schering Aktiengesellschaft | 11-Beta-Aryl-Estradiene, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate |
DE3347126A1 (de) * | 1983-12-22 | 1985-07-11 | Schering AG, 1000 Berlin und 4709 Bergkamen | 11ss-aryl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate |
AU580843B2 (en) * | 1985-02-07 | 1989-02-02 | Schering Aktiengesellschaft | 11``-phenyl-gonanes, their manufacture and pharmaceutical preparations containing them |
-
1987
- 1987-07-16 DE DE19873723788 patent/DE3723788A1/de not_active Withdrawn
-
1988
- 1988-07-15 AT AT88730161T patent/ATE87631T1/de not_active IP Right Cessation
- 1988-07-15 JP JP63505988A patent/JP2792876B2/ja not_active Expired - Lifetime
- 1988-07-15 DD DD88317992A patent/DD281809A5/de not_active IP Right Cessation
- 1988-07-15 ES ES88730161T patent/ES2054859T3/es not_active Expired - Lifetime
- 1988-07-15 US US07/458,668 patent/US5132299A/en not_active Expired - Fee Related
- 1988-07-15 HU HU884582A patent/HU203764B/hu not_active IP Right Cessation
- 1988-07-15 EP EP88730161A patent/EP0299913B1/de not_active Expired - Lifetime
- 1988-07-15 DE DE8888730161T patent/DE3879787D1/de not_active Expired - Fee Related
- 1988-07-15 WO PCT/DE1988/000447 patent/WO1989000578A1/de active IP Right Grant
- 1988-07-15 CA CA000572238A patent/CA1320946C/en not_active Expired - Fee Related
-
1989
- 1989-01-31 DK DK043189A patent/DK43189A/da not_active Application Discontinuation
-
1990
- 1990-01-15 FI FI900217A patent/FI94349C/fi not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FI94349C (fi) | 1995-08-25 |
FI94349B (fi) | 1995-05-15 |
ES2054859T3 (es) | 1994-08-16 |
JP2792876B2 (ja) | 1998-09-03 |
DK43189D0 (da) | 1989-01-31 |
DE3723788A1 (de) | 1989-01-26 |
JPH03500642A (ja) | 1991-02-14 |
DD281809A5 (de) | 1990-08-22 |
EP0299913A1 (de) | 1989-01-18 |
US5132299A (en) | 1992-07-21 |
CA1320946C (en) | 1993-08-03 |
EP0299913B1 (de) | 1993-03-31 |
ATE87631T1 (de) | 1993-04-15 |
WO1989000578A1 (en) | 1989-01-26 |
HU203764B (en) | 1991-09-30 |
HUT52112A (en) | 1990-06-28 |
DE3879787D1 (de) | 1993-05-06 |
DK43189A (da) | 1989-01-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB | Publication of examined application | ||
MM | Patent lapsed | ||
MM | Patent lapsed |
Owner name: SCHERING AKTIENGESELLSCHAFT |