DK43189D0 - 11beta-phenyl-4,9,15-oestratriener, deres fremstilling og farmaceutiske praeparater indeholdende dem - Google Patents

11beta-phenyl-4,9,15-oestratriener, deres fremstilling og farmaceutiske praeparater indeholdende dem

Info

Publication number
DK43189D0
DK43189D0 DK043189A DK43189A DK43189D0 DK 43189 D0 DK43189 D0 DK 43189D0 DK 043189 A DK043189 A DK 043189A DK 43189 A DK43189 A DK 43189A DK 43189 D0 DK43189 D0 DK 43189D0
Authority
DK
Denmark
Prior art keywords
implies
pct
carbon atoms
hydrogen atom
case
Prior art date
Application number
DK043189A
Other languages
English (en)
Other versions
DK43189A (da
Inventor
Eckhard Ottow
Helmut Hofmeister
Stefan Scholz
Guenter Neef
Walter Elger
Sybille Beier
Krzysztof Chwalisz
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK43189A publication Critical patent/DK43189A/da
Publication of DK43189D0 publication Critical patent/DK43189D0/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0096—Alkynyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK043189A 1987-07-16 1989-01-31 11beta-phenyl-4,9,15-oestratriener, deres fremstilling og farmaceutiske praeparater indeholdende dem DK43189D0 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19873723788 DE3723788A1 (de) 1987-07-16 1987-07-16 11(beta)-phenyl-4,9,15-estratriene, deren herstellung und diese enthaltende pharmazeutische praeparate
PCT/DE1988/000447 WO1989000578A1 (en) 1987-07-16 1988-07-15 11beta-PHENYL-4,9,15-ESTRATRIENES, THEIR MANUFACTURE, AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM

Publications (2)

Publication Number Publication Date
DK43189A DK43189A (da) 1989-01-31
DK43189D0 true DK43189D0 (da) 1989-01-31

Family

ID=6331846

Family Applications (1)

Application Number Title Priority Date Filing Date
DK043189A DK43189D0 (da) 1987-07-16 1989-01-31 11beta-phenyl-4,9,15-oestratriener, deres fremstilling og farmaceutiske praeparater indeholdende dem

Country Status (12)

Country Link
US (1) US5132299A (da)
EP (1) EP0299913B1 (da)
JP (1) JP2792876B2 (da)
AT (1) ATE87631T1 (da)
CA (1) CA1320946C (da)
DD (1) DD281809A5 (da)
DE (2) DE3723788A1 (da)
DK (1) DK43189D0 (da)
ES (1) ES2054859T3 (da)
FI (1) FI94349C (da)
HU (1) HU203764B (da)
WO (1) WO1989000578A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3917274A1 (de) * 1989-05-24 1990-11-29 Schering Ag 9(alpha)-hydroxy-19, 11(beta)-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate
DK0411733T3 (da) * 1989-08-04 1999-06-28 Schering Ag 11-beta-aryl-gona-4,9-dien-3-oner
DE4042004A1 (de) * 1990-12-22 1992-06-25 Schering Ag 14(beta)-h-, 14- u. 15-en-11(beta)-aryl-4-estrene
US5407928A (en) * 1990-08-15 1995-04-18 Schering Aktiengesellschaft 11β-aryl-gona-4,9-dien-3-ones
US5780220A (en) * 1994-05-19 1998-07-14 Trustees Of The University Of Pennsylvania Methods and compositions for inhibiting HIV replication
US5639598A (en) * 1994-05-19 1997-06-17 The Trustees Of The University Of Pennsylvania Method and kit for identification of antiviral agents capable of abrogating HIV Vpr-Rip-1 binding interactions
US5767113A (en) * 1995-05-10 1998-06-16 The Salk Institute For Biological Studies Compounds useful for concurrently activating glucocorticoid-induced response and reducing multidrug resistance
DE19706061A1 (de) * 1997-02-07 1998-08-13 Schering Ag Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette
US6090798A (en) * 1997-12-19 2000-07-18 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with glucocorticoid antagonists
DE102004059880A1 (de) * 2004-12-10 2006-06-14 Grünenthal GmbH Stabiles, hormonhaltiges (Zwischen-)Produkt
EP2576582B1 (en) 2010-05-26 2019-09-18 Corcept Therapeutics, Inc. Treatment of muscular dystrophy
CN107530435A (zh) 2015-03-02 2018-01-02 科赛普特治疗学股份有限公司 使用糖皮质激素受体拮抗剂和生长抑素治疗acth分泌型肿瘤
WO2016160969A1 (en) 2015-03-30 2016-10-06 Corcept Therapeutics, Inc. Use of glucocorticoid receptor antagonists in combination with glucocorticoids to treat adrenal insufficiency
AU2016305092B2 (en) 2015-08-13 2022-01-27 Corcept Therapeutics, Inc. Method for differentially diagnosing ACTH-dependent Cushing's syndrome
EP3405101B1 (en) 2016-01-19 2020-12-23 Corcept Therapeutics, Inc. Differential diagnosis of ectopic cushing's syndrome
EP3641780A4 (en) 2017-06-20 2021-02-24 Corcept Therapeutics, Inc. TREATMENT METHODS OF NEURO-EPITHELIAL TUMORS USING SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS
EP3713086A1 (de) 2019-03-18 2020-09-23 Siemens Aktiengesellschaft Schutzschaltung für einen halbleiterschalter
EP4263807A2 (en) 2020-12-18 2023-10-25 Instil Bio (Uk) Limited Processing of tumor infiltrating lymphocytes

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2530817A (en) * 1948-05-19 1950-11-21 Univ Pennsylvania 13-monomethyl steroids
US2940968A (en) * 1958-10-01 1960-06-14 Merck & Co Inc Dimethylated steroids and processes for producing same
CH558346A (de) * 1971-06-17 1975-01-31 Sandoz Ag Verfahren zur herstellung neuer 3-oximino-17(alpha)-propadienyl-substituierter steroide.
DE3042529A1 (de) * 1980-11-07 1982-06-24 Schering Ag, 1000 Berlin Und 4619 Bergkamen 11-methylen- (delta)(pfeil hoch)1(pfeil hoch)(pfeil hoch)5(pfeil hoch) -steroide, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
FR2522328B1 (fr) * 1982-03-01 1986-02-14 Roussel Uclaf Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments
DE3461090D1 (en) * 1983-02-18 1986-12-04 Schering Ag 11-beta-aryl-estradienes, process for their preparation and pharmaceutical compositions containing them
DE3347126A1 (de) * 1983-12-22 1985-07-11 Schering AG, 1000 Berlin und 4709 Bergkamen 11ss-aryl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate
NZ214998A (en) * 1985-02-07 1989-06-28 Schering Ag 13-(methyl or ethyl)-11-beta-phenyl-gonane derivatives; preparatory processes and pharmaceutical compositions

Also Published As

Publication number Publication date
DK43189A (da) 1989-01-31
DE3879787D1 (de) 1993-05-06
ES2054859T3 (es) 1994-08-16
FI94349B (fi) 1995-05-15
DE3723788A1 (de) 1989-01-26
US5132299A (en) 1992-07-21
JPH03500642A (ja) 1991-02-14
ATE87631T1 (de) 1993-04-15
HU203764B (en) 1991-09-30
EP0299913A1 (de) 1989-01-18
FI94349C (fi) 1995-08-25
WO1989000578A1 (en) 1989-01-26
FI900217A0 (fi) 1990-01-15
HUT52112A (en) 1990-06-28
DD281809A5 (de) 1990-08-22
CA1320946C (en) 1993-08-03
JP2792876B2 (ja) 1998-09-03
EP0299913B1 (de) 1993-03-31

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment