FI893509A - Makrocykliska polyazafoereningar, vilka innehaoller en 5- eller 6-ring, foerfaranden foer framstaellning daerav och dessa innehaollande farmaceutiska medel. - Google Patents

Makrocykliska polyazafoereningar, vilka innehaoller en 5- eller 6-ring, foerfaranden foer framstaellning daerav och dessa innehaollande farmaceutiska medel. Download PDF

Info

Publication number
FI893509A
FI893509A FI893509A FI893509A FI893509A FI 893509 A FI893509 A FI 893509A FI 893509 A FI893509 A FI 893509A FI 893509 A FI893509 A FI 893509A FI 893509 A FI893509 A FI 893509A
Authority
FI
Finland
Prior art keywords
group
radical
atom
image
hydrogen
Prior art date
Application number
FI893509A
Other languages
English (en)
Finnish (fi)
Other versions
FI893509A0 (fi
Inventor
Johannes Platzek
Bernd Raduechel
Heinz Gries
Hans-Joachim Weinmann
Ulrich Speck
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of FI893509A0 publication Critical patent/FI893509A0/fi
Publication of FI893509A publication Critical patent/FI893509A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
    • C07D255/04—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/08—Bridged systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
FI893509A 1988-07-20 1989-07-20 Makrocykliska polyazafoereningar, vilka innehaoller en 5- eller 6-ring, foerfaranden foer framstaellning daerav och dessa innehaollande farmaceutiska medel. FI893509A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3825040A DE3825040A1 (de) 1988-07-20 1988-07-20 5- oder 6-ring- enthaltende makrocyclische polyaza-verbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel

Publications (2)

Publication Number Publication Date
FI893509A0 FI893509A0 (fi) 1989-07-20
FI893509A true FI893509A (fi) 1990-01-21

Family

ID=6359368

Family Applications (1)

Application Number Title Priority Date Filing Date
FI893509A FI893509A (fi) 1988-07-20 1989-07-20 Makrocykliska polyazafoereningar, vilka innehaoller en 5- eller 6-ring, foerfaranden foer framstaellning daerav och dessa innehaollande farmaceutiska medel.

Country Status (15)

Country Link
EP (1) EP0352218B1 (da)
JP (1) JP2877844B2 (da)
AT (1) ATE118775T1 (da)
CA (1) CA1341035C (da)
DE (2) DE3825040A1 (da)
DK (1) DK171097B1 (da)
ES (1) ES2068908T3 (da)
FI (1) FI893509A (da)
GR (1) GR3015162T3 (da)
IE (1) IE66693B1 (da)
IL (1) IL91046A (da)
NO (1) NO179104C (da)
NZ (1) NZ229996A (da)
PT (1) PT91211B (da)
ZA (1) ZA895543B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5334371A (en) * 1988-07-20 1994-08-02 Schering Aktiengesellschaft Marcocyclic polyaza bicyclo compounds containing 5 or 6 membered rings, and method for MRI
DE4001655A1 (de) * 1990-01-18 1991-07-25 Schering Ag 6-ring enthaltende makrocyclische tetraaza-verbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
RU2108388C1 (ru) * 1989-01-17 1998-04-10 Суомен Ксюрофин Ой Способ получения ксилита из водного раствора ксилозы
FR2652589B1 (fr) * 1989-10-04 1995-02-17 Roquette Freres Procede de fabrication de xylitol et de produits riches en xylitol.
GB9001245D0 (en) * 1990-01-19 1990-03-21 Salutar Inc Compounds
EP0511275A1 (en) * 1990-01-19 1992-11-04 Nycomed Imaging As Chelating compounds
US5330737A (en) * 1991-12-06 1994-07-19 Mallinckrodt Medical, Inc. Nitrogen-sulfur ligands as opiate receptor drug mimics
WO1993011800A1 (en) * 1991-12-10 1993-06-24 The Dow Chemical Company Bicycle-polyazamacrocyclocarboxylic acid complexes, conjugates, preparation and use as contrast agents
US5739294A (en) * 1991-12-10 1998-04-14 The Dow Chemical Company Bicyclopol yazamacrocyclophosphonic acid complexes for use as contrast agents
US5428139A (en) * 1991-12-10 1995-06-27 The Dow Chemical Company Bicyclopolyazamacrocyclophosphonic acid complexes for use as radiopharmaceuticals
WO1994026313A1 (en) * 1993-05-06 1994-11-24 The Dow Chemical Company Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates, processes for their preparation, and use as contrast agents
SG46598A1 (en) * 1991-12-10 1998-02-20 Dow Chemical Co Bicycloazamacroyclophosphonic acid conjugates contrast agents and preparation
AU3275293A (en) * 1991-12-10 1993-07-19 Dow Chemical Company, The Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates processes for their preparation, and use as radiopharmaceuticals
US5480990A (en) * 1991-12-10 1996-01-02 The Dow Chemical Company Bicyclopolyazamacrocyclocarboxylic acid complexes for use as contrast agents
US5385893A (en) * 1993-05-06 1995-01-31 The Dow Chemical Company Tricyclopolyazamacrocyclophosphonic acids, complexes and derivatives thereof, for use as contrast agents
AU4237493A (en) * 1993-05-06 1994-12-12 Dow Chemical Company, The Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates, processes for their preparation, and use as radiopharmaceuticals
US5480970A (en) * 1993-12-22 1996-01-02 Resolution Pharmaceuticals Metal chelators
US5569745A (en) * 1994-02-25 1996-10-29 Resolution Pharmaceuticals Inc. Peptide-Chelator conjugates
CA2251924C (en) * 1996-04-19 2006-05-30 The Dow Chemical Company Fluorescent chelates as visual tissue specific imaging agents
FR2794744B1 (fr) * 1999-06-09 2001-09-21 Guerbet Sa Complexes metalliques de polyaminoacides bicycliques, leur procede de preparation et leur application en imagerie medicale
JP2004509924A (ja) * 2000-09-25 2004-04-02 ザ、プロクター、エンド、ギャンブル、カンパニー Ｍｒｉ画像増強組成物
EP1940841B9 (fr) * 2005-10-07 2017-04-19 Guerbet Composes comprenant une partie de reconnaissance d'une cible biologique, couplee a une partie de signal capable de complexer le gallium
FR2891830B1 (fr) * 2005-10-07 2011-06-24 Guerbet Sa Composes a chaines aminoalcools courtes et complexes metalliques pour l'imagerie medicale
US8986650B2 (en) 2005-10-07 2015-03-24 Guerbet Complex folate-NOTA-Ga68
GB201610738D0 (en) 2016-06-20 2016-08-03 Ge Healthcare As Chelate compounds
EP3728168B1 (en) * 2017-12-20 2022-03-30 General Electric Company Anionic chelate compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2478456A (en) 1946-03-15 1949-08-09 Socony Vaeuum Oil Company Inc Solvent dewaxing
US3194818A (en) 1963-08-14 1965-07-13 Sterling Drug Inc Alpha-aryl or aralkyl furfurylamines
DE3129906C3 (de) * 1981-07-24 1996-12-19 Schering Ag Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik
DE3150917A1 (de) 1981-12-18 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen "2-amino-1-(1,3-dioxolan-4-yl)-ethanol-verbindungen, deren herstellung und verwendung zur weiterverarbeitung"
NL194579C (nl) * 1983-01-21 2002-08-05 Schering Ag Diagnostisch middel.
DE3324235A1 (de) * 1983-07-01 1985-01-10 Schering AG, 1000 Berlin und 4709 Bergkamen Neue komplexbildner, komplexe und komplexsalze
SE8502573D0 (sv) * 1985-05-23 1985-05-23 Jouko Kanakre Fluorescent lanthanide chelates useful as labels of physiologically active materials
DE3772785D1 (de) 1986-01-23 1991-10-17 Squibb & Sons Inc 1-substituiertes-4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododecan und analoga.

Also Published As

Publication number Publication date
JP2877844B2 (ja) 1999-04-05
NO892959L (no) 1990-01-22
ZA895543B (en) 1990-05-30
DK171097B1 (da) 1996-06-03
NO892959D0 (no) 1989-07-19
IL91046A (en) 1995-10-31
IE892335L (en) 1990-01-20
FI893509A0 (fi) 1989-07-20
DK358889A (da) 1990-01-21
PT91211A (pt) 1990-02-08
NO179104C (no) 1996-08-07
NZ229996A (en) 1992-05-26
PT91211B (pt) 1995-03-01
EP0352218B1 (de) 1995-02-22
CA1341035C (en) 2000-06-20
DK358889D0 (da) 1989-07-19
AU637052B2 (en) 1993-05-20
IL91046A0 (en) 1990-02-09
ATE118775T1 (de) 1995-03-15
JPH02104588A (ja) 1990-04-17
GR3015162T3 (en) 1995-05-31
DE3825040A1 (de) 1990-01-25
IE66693B1 (en) 1996-01-24
NO179104B (no) 1996-04-29
DE58909022D1 (de) 1995-04-06
EP0352218A2 (de) 1990-01-24
EP0352218A3 (de) 1991-01-16
AU3827589A (en) 1990-02-01
ES2068908T3 (es) 1995-05-01

Similar Documents

Publication Publication Date Title
FI893509A (fi) Makrocykliska polyazafoereningar, vilka innehaoller en 5- eller 6-ring, foerfaranden foer framstaellning daerav och dessa innehaollande farmaceutiska medel.
ES2091865T3 (es) Tetraaza-compuestos macrociclicos que contienen 6 anillos, procedimiento para su preparacion y agentes farmaceuticos que los contienen.
FR2662162B1 (fr) Nouveaux derives de l'amino piperidine, de l'amino pyrrolidine et de l'amino perhydroazepine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
PT673937E (pt) Derivados biciclicos heterociclicos de sulfonamida e de ester sulfonico
DE69305276D1 (de) Arylglycinamidderivate, Verfahren zur deren Herstellung und deren Verwendung zur Therapie der Dysurie
DK640489A (da) C63-amidderivater af 34-de-(acetylglucosaminyl)-34-deoxy-teicoplaniner
DE69426620D1 (de) Antidepressiva
NO910965D0 (no) Aminderivater med fungicid aktivitet.

Legal Events

Date Code Title Description
FD Application lapsed
FD Application lapsed

Owner name: SCHERING AKTIENGESELLSCHAFT