FI892012A - Menetelmä uusien terapeuttisesti käyttökelpoisten 4-fenyyli-piperidiiniyhdisteiden valmistamiseksi - Google Patents
Menetelmä uusien terapeuttisesti käyttökelpoisten 4-fenyyli-piperidiiniyhdisteiden valmistamiseksi Download PDFInfo
- Publication number
- FI892012A FI892012A FI892012A FI892012A FI892012A FI 892012 A FI892012 A FI 892012A FI 892012 A FI892012 A FI 892012A FI 892012 A FI892012 A FI 892012A FI 892012 A FI892012 A FI 892012A
- Authority
- FI
- Finland
- Prior art keywords
- alkoxy
- alkyl
- cyano
- aryl
- halogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK231088 | 1988-04-28 | ||
| DK231088A DK231088D0 (da) | 1988-04-28 | 1988-04-28 | Piperidinforbindelser, deres fremstilling og anvendelse |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI892012A0 FI892012A0 (fi) | 1989-04-27 |
| FI892012A true FI892012A (fi) | 1989-10-29 |
| FI92822B FI92822B (fi) | 1994-09-30 |
| FI92822C FI92822C (fi) | 1995-01-10 |
Family
ID=8111522
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI892012A FI92822C (fi) | 1988-04-28 | 1989-04-27 | Menetelmä uusien terapeuttisesti käyttökelpoisten 4-fenyyli-piperidiiniyhdisteiden valmistamiseksi |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0339579B1 (fi) |
| JP (1) | JP2857414B2 (fi) |
| KR (1) | KR900016175A (fi) |
| CN (1) | CN1037332A (fi) |
| AT (1) | ATE168375T1 (fi) |
| AU (1) | AU631121B2 (fi) |
| DE (1) | DE68928735T2 (fi) |
| DK (1) | DK231088D0 (fi) |
| ES (1) | ES2118708T3 (fi) |
| FI (1) | FI92822C (fi) |
| HU (1) | HUT55387A (fi) |
| IL (1) | IL89903A0 (fi) |
| NO (1) | NO173826C (fi) |
| NZ (1) | NZ228895A (fi) |
| PT (1) | PT90412B (fi) |
| ZA (1) | ZA893003B (fi) |
| ZW (1) | ZW4889A1 (fi) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK640289D0 (da) * | 1989-12-18 | 1989-12-18 | Ferrosan As | Ny heterocyklisk kemi |
| IL98757A (en) * | 1990-07-18 | 1997-01-10 | Novo Nordisk As | Piperidine derivatives their preparation and pharmaceutical compositions containing them |
| GB9226111D0 (en) * | 1992-12-15 | 1993-02-10 | Smithkline Beecham Plc | Madicaments |
| US5859001A (en) * | 1996-01-11 | 1999-01-12 | University Of Florida Research Foundation, Inc. | Neuroprotective effects of polycyclic phenolic compounds |
| US6319914B1 (en) | 1993-11-05 | 2001-11-20 | Apollo Biopharmaceuticals, Inc. | Cytoprotective effect of polycyclic phenolic compounds |
| US6197833B1 (en) | 1995-07-24 | 2001-03-06 | Apollo Biopharmaceutics, Inc. | Neuroprotective effects of polycyclic phenolic compounds |
| ES2102295B1 (es) * | 1994-03-18 | 1998-04-01 | Ferrer Int | Nuevos compuestos derivados de la n-benzoilmetil-piperidina. |
| ES2174058T3 (es) * | 1995-02-28 | 2002-11-01 | Suntory Ltd | Derivados de arilpiperidina y arilpiperazina, y farmacos que lo contienen. |
| WO1997003661A1 (en) * | 1995-07-24 | 1997-02-06 | University Of Florida Research Foundation, Incorporated | Use of non-estrogen polycyclic phenol compounds for the manufacture of a medicament for conferring neuroprotection to cells |
| ES2117557B1 (es) * | 1996-02-29 | 1999-07-01 | Ferrer Int | Nuevo procedimiento de obtencion de (-)-trans -n-p-fluorobenzoilmetil-4-(p-fluorofenil)-3- ((3,4-(metilendioxi)fenoxi ) metil)-piperidina. |
| ES2225979T3 (es) | 1996-07-22 | 2005-03-16 | Daiichi Suntory Pharma Co., Ltd. | Derivados de arilpiperidinol y de arilpiperidina y farmacos que los contienen. |
| WO1998003172A1 (fr) * | 1996-07-22 | 1998-01-29 | Suntory Limited | Derives arylpiperidinol et arylpiperidine et medicaments les contenant |
| EP0975595B9 (en) * | 1997-04-07 | 2009-09-16 | Georgetown University | Analogs of cocaine |
| US6376672B1 (en) * | 1999-04-27 | 2002-04-23 | Hoffmann-La Roche Inc. | Naphthalenylmethoxypiperidines as renin inhibitors |
| WO2001032178A1 (en) * | 1999-10-29 | 2001-05-10 | Novo Nordisk A/S | Use of 3,4-substituted piperidines |
| WO2004043921A1 (en) * | 2002-11-11 | 2004-05-27 | Natco Pharma Limited | Novel process for the preparation of 4-aryl-3-hydroxymethyl-1-methylpiperidines. |
| US20070142389A1 (en) * | 2005-12-20 | 2007-06-21 | Pfizer Inc. | Piperidine derivatives |
| EP4086249A3 (en) * | 2015-09-02 | 2023-02-15 | Trevena, Inc. | 6-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same |
| KR20190129867A (ko) | 2017-02-17 | 2019-11-20 | 트레베나, 인코포레이티드. | 5-원 아자-헤테로고리 함유 델타-오피오이드 수용체 조절 화합물, 및 그의 사용 및 제조 방법 |
| CA3052479A1 (en) | 2017-02-17 | 2018-08-23 | Trevena, Inc. | 7-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
| EP0190496A3 (en) * | 1984-12-13 | 1987-05-27 | Beecham Group Plc | Piperidine derivatives having a gastro-intestinal activity |
| ES2058061T3 (es) * | 1985-10-25 | 1994-11-01 | Beecham Group Plc | Derivado de piperidina, su preparacion y su uso como medicamento. |
| IE66332B1 (en) * | 1986-11-03 | 1995-12-27 | Novo Nordisk As | Piperidine compounds and their preparation and use |
-
1988
- 1988-04-28 DK DK231088A patent/DK231088D0/da not_active Application Discontinuation
-
1989
- 1989-04-10 IL IL89903A patent/IL89903A0/xx not_active IP Right Cessation
- 1989-04-12 ZW ZW48/89A patent/ZW4889A1/xx unknown
- 1989-04-24 AU AU33366/89A patent/AU631121B2/en not_active Ceased
- 1989-04-24 ZA ZA893003A patent/ZA893003B/xx unknown
- 1989-04-25 DE DE68928735T patent/DE68928735T2/de not_active Expired - Fee Related
- 1989-04-25 AT AT89107481T patent/ATE168375T1/de active
- 1989-04-25 ES ES89107481T patent/ES2118708T3/es not_active Expired - Lifetime
- 1989-04-25 EP EP89107481A patent/EP0339579B1/en not_active Expired - Lifetime
- 1989-04-26 NZ NZ228895A patent/NZ228895A/en unknown
- 1989-04-27 NO NO891762A patent/NO173826C/no unknown
- 1989-04-27 HU HU892019A patent/HUT55387A/hu unknown
- 1989-04-27 FI FI892012A patent/FI92822C/fi not_active IP Right Cessation
- 1989-04-28 KR KR1019890005606A patent/KR900016175A/ko not_active Application Discontinuation
- 1989-04-28 CN CN89102923A patent/CN1037332A/zh active Pending
- 1989-04-28 PT PT90412A patent/PT90412B/pt not_active IP Right Cessation
- 1989-04-28 JP JP1107889A patent/JP2857414B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NO173826C (no) | 1994-02-09 |
| IL89903A0 (en) | 1989-12-15 |
| DK231088D0 (da) | 1988-04-28 |
| DE68928735D1 (de) | 1998-08-20 |
| EP0339579B1 (en) | 1998-07-15 |
| AU3336689A (en) | 1989-11-02 |
| ATE168375T1 (de) | 1998-08-15 |
| NO891762D0 (no) | 1989-04-27 |
| FI92822B (fi) | 1994-09-30 |
| JPH01313461A (ja) | 1989-12-18 |
| PT90412B (pt) | 1994-09-30 |
| KR900016175A (ko) | 1990-11-12 |
| NO173826B (no) | 1993-11-01 |
| DE68928735T2 (de) | 1998-11-19 |
| ZA893003B (en) | 1989-12-27 |
| AU631121B2 (en) | 1992-11-19 |
| JP2857414B2 (ja) | 1999-02-17 |
| CN1037332A (zh) | 1989-11-22 |
| HUT55387A (en) | 1991-05-28 |
| NO891762L (no) | 1989-10-30 |
| FI92822C (fi) | 1995-01-10 |
| NZ228895A (en) | 1992-05-26 |
| FI892012A0 (fi) | 1989-04-27 |
| ES2118708T3 (es) | 1998-10-01 |
| ZW4889A1 (en) | 1989-08-09 |
| EP0339579A3 (en) | 1991-12-18 |
| EP0339579A2 (en) | 1989-11-02 |
| PT90412A (pt) | 1989-11-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI892012A (fi) | Menetelmä uusien terapeuttisesti käyttökelpoisten 4-fenyyli-piperidiiniyhdisteiden valmistamiseksi | |
| CA2106200A1 (en) | Stereoselective preparation of substituted piperidines | |
| FI885592A (fi) | Aryloxifenylpropylaminer, deras framstaellning och anvaendning. | |
| ES2068216T3 (es) | Compuestos de tienotriazolodiazepina y usos farmaceuticos de los mismos. | |
| IT1213028B (it) | Composti piperidinici atti all'impiego come stabilizzanti per polimeri sintetici. | |
| IN164615B (fi) | ||
| DK0488345T3 (da) | Optisk aktive 1,4-dihydropyridinderivater og fremgangsmåder til fremstilling deraf | |
| DE69015324D1 (de) | Herstellung von gegebenenfalls substituierten Chinolincopolymeren. | |
| FR2640032B1 (fr) | Methode de production d'oxygene ultra-pur | |
| ATE76407T1 (de) | T-butyl ergolinderivate. | |
| DK187689A (da) | Piperidine forbindelser, deres fremstilling og anvendelse | |
| FR2633289B1 (fr) | Procede de fabrication de l'acetate de vinyle | |
| DK560887A (da) | Piperidin forbindelser, deres fremstilling og anvendelse | |
| ATE27805T1 (de) | Fluorierte verbindungen mit analgetischer und entzuendungshemmender wirkung. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB | Publication of examined application | ||
| MM | Patent lapsed | ||
| MM | Patent lapsed |
Owner name: NOVO NORDISK A/S |