FI883959A - 3'-demetoxiepipodofyllotoxin -glukosidderivat. - Google Patents

3'-demetoxiepipodofyllotoxin -glukosidderivat. Download PDF

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Publication number
FI883959A
FI883959A FI883959A FI883959A FI883959A FI 883959 A FI883959 A FI 883959A FI 883959 A FI883959 A FI 883959A FI 883959 A FI883959 A FI 883959A FI 883959 A FI883959 A FI 883959A
Authority
FI
Finland
Prior art keywords
demetoxiepipodofyllotoxin
glucoside derivatives
glucoside
derivatives
demetoxiepipodofyllotoxin glucoside
Prior art date
Application number
FI883959A
Other languages
English (en)
Other versions
FI883959A0 (fi
FI88168B (fi
FI88168C (fi
Inventor
Mark George Saulnier
Dolatrai Mohanlal Vyas
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI883959A0 publication Critical patent/FI883959A0/fi
Publication of FI883959A publication Critical patent/FI883959A/fi
Publication of FI88168B publication Critical patent/FI88168B/fi
Application granted granted Critical
Publication of FI88168C publication Critical patent/FI88168C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FI883959A 1987-08-31 1988-08-26 Foerfarande foer framstaellning av 3'-demetoxiepipodofyllotoxinglukosidderivat FI88168C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/091,570 US4888419A (en) 1987-08-31 1987-08-31 3'-demethoxyepipodophyllotoxin glucoside derivatives
US9157087 1987-08-31

Publications (4)

Publication Number Publication Date
FI883959A0 FI883959A0 (fi) 1988-08-26
FI883959A true FI883959A (fi) 1989-03-01
FI88168B FI88168B (fi) 1992-12-31
FI88168C FI88168C (fi) 1993-04-13

Family

ID=22228465

Family Applications (1)

Application Number Title Priority Date Filing Date
FI883959A FI88168C (fi) 1987-08-31 1988-08-26 Foerfarande foer framstaellning av 3'-demetoxiepipodofyllotoxinglukosidderivat

Country Status (13)

Country Link
US (1) US4888419A (fi)
EP (1) EP0305972A3 (fi)
JP (1) JPS6471898A (fi)
KR (1) KR900006236B1 (fi)
AU (1) AU620561B2 (fi)
CA (1) CA1311472C (fi)
DK (1) DK482488A (fi)
FI (1) FI88168C (fi)
IL (1) IL87586A (fi)
NO (1) NO168040C (fi)
NZ (1) NZ225879A (fi)
PT (1) PT88375B (fi)
ZA (1) ZA883763B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4853467A (en) * 1987-05-19 1989-08-01 Bristol-Myers Company Nitrogen containing derivatives of epipodophyllotoxin glucosides
US4965348A (en) * 1989-05-19 1990-10-23 Bristol-Myers Company Dimeric epipodophyllotoxin glucoside derivatives
US5036055A (en) * 1989-06-07 1991-07-30 Bristol-Myers Company Acylated derivatives of etoposide
US5081234A (en) * 1990-04-30 1992-01-14 Bristol-Myers Squibb Co. 4'-demethylepipodophyllotoxin glycosides
US5459248A (en) * 1993-11-04 1995-10-17 Bristol-Myers Squibb Company Process of preparing etoposide phosphate and etoposide
US6207673B1 (en) 1997-03-12 2001-03-27 The University Of North Carolina At Chapel Hill Covalent conjugates of topoisomerase I and topoisomerase II inhibitors
US6051721A (en) * 1997-10-02 2000-04-18 The Board Of Regents Of The University Of Nebraska Ring E-modified analogues of(-)-podophyllotoxin and etoposide and a method for their synthesis
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US608815A (en) * 1898-08-09 Wagon-pole coupling
GB823068A (en) * 1955-05-13 1959-11-04 Sandoz Ltd Condensation products from glucosides
NL6613143A (fi) * 1965-09-21 1967-03-22
CH464957A (de) * 1965-12-14 1968-11-15 Sandoz Ag Verfahren zur Herstellung eines neuen Glucosids
FR1518705A (fr) * 1965-12-14 1968-03-29 Sandoz Sa Procédé de préparation d'un nouveau glucoside
US4547564A (en) * 1982-12-27 1985-10-15 General Electric Company Polyester carbonate from branched chain alkylidene dihydric phenol
JPS6032799A (ja) * 1983-07-29 1985-02-19 Microbial Chem Res Found 新規４′−デメチル−４−エピポドフィロトキシン誘導体
JPS60246393A (ja) * 1984-05-22 1985-12-06 Nippon Kayaku Co Ltd エトポシドの新規製造法
US4609644A (en) * 1984-06-15 1986-09-02 St. Jude Children's Research Hospital Epipodophyllotoxinquinone glucoside derivatives, method of production and use
US4853467A (en) * 1987-05-19 1989-08-01 Bristol-Myers Company Nitrogen containing derivatives of epipodophyllotoxin glucosides
US4874851A (en) * 1987-07-01 1989-10-17 Bristol-Meyers Company 3',4'-dinitrogen substituted epipodophyllotoxin glucoside derivatives

Also Published As

Publication number Publication date
FI883959A0 (fi) 1988-08-26
NO883857L (no) 1989-03-01
KR900006236B1 (ko) 1990-08-27
DK482488D0 (da) 1988-08-30
US4888419A (en) 1989-12-19
NO168040B (no) 1991-09-30
FI88168B (fi) 1992-12-31
IL87586A (en) 1993-07-08
ZA883763B (en) 1989-10-25
NZ225879A (en) 1991-04-26
NO883857D0 (no) 1988-08-30
CA1311472C (en) 1992-12-15
EP0305972A3 (en) 1990-08-22
PT88375B (pt) 1995-03-31
JPS6471898A (en) 1989-03-16
EP0305972A2 (en) 1989-03-08
NO168040C (no) 1992-01-08
PT88375A (pt) 1989-06-30
FI88168C (fi) 1993-04-13
KR890003793A (ko) 1989-04-18
AU2166688A (en) 1989-03-02
DK482488A (da) 1989-03-01
IL87586A0 (en) 1989-01-31
AU620561B2 (en) 1992-02-20
JPH0453877B2 (fi) 1992-08-27

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MM Patent lapsed

Owner name: BRISTOL-MYERS SQUIBB COMPANY