PT88375A - Processo para a preparacao de derivados glucosidicos da 3'-demetoxiepipodofilotoxina e de composicoes farmaceuticas que os contem - Google Patents
Processo para a preparacao de derivados glucosidicos da 3'-demetoxiepipodofilotoxina e de composicoes farmaceuticas que os contemInfo
- Publication number
- PT88375A PT88375A PT88375A PT8837588A PT88375A PT 88375 A PT88375 A PT 88375A PT 88375 A PT88375 A PT 88375A PT 8837588 A PT8837588 A PT 8837588A PT 88375 A PT88375 A PT 88375A
- Authority
- PT
- Portugal
- Prior art keywords
- demetoxyepipodophotoxin
- preparation
- pharmaceutical compositions
- compositions containing
- glucosidic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/091,570 US4888419A (en) | 1987-08-31 | 1987-08-31 | 3'-demethoxyepipodophyllotoxin glucoside derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT88375A true PT88375A (pt) | 1989-06-30 |
| PT88375B PT88375B (pt) | 1995-03-31 |
Family
ID=22228465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT88375A PT88375B (pt) | 1987-08-31 | 1988-08-30 | Processo para a preparacao de derivados glucosidicos da 3'-demetoxiepipodofilotoxina e de composicoes farmaceuticas que os contem |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4888419A (pt) |
| EP (1) | EP0305972A3 (pt) |
| JP (1) | JPS6471898A (pt) |
| KR (1) | KR900006236B1 (pt) |
| AU (1) | AU620561B2 (pt) |
| CA (1) | CA1311472C (pt) |
| DK (1) | DK482488A (pt) |
| FI (1) | FI88168C (pt) |
| IL (1) | IL87586A (pt) |
| NO (1) | NO168040C (pt) |
| NZ (1) | NZ225879A (pt) |
| PT (1) | PT88375B (pt) |
| ZA (1) | ZA883763B (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4853467A (en) * | 1987-05-19 | 1989-08-01 | Bristol-Myers Company | Nitrogen containing derivatives of epipodophyllotoxin glucosides |
| US4965348A (en) * | 1989-05-19 | 1990-10-23 | Bristol-Myers Company | Dimeric epipodophyllotoxin glucoside derivatives |
| US5036055A (en) * | 1989-06-07 | 1991-07-30 | Bristol-Myers Company | Acylated derivatives of etoposide |
| US5081234A (en) * | 1990-04-30 | 1992-01-14 | Bristol-Myers Squibb Co. | 4'-demethylepipodophyllotoxin glycosides |
| US5459248A (en) * | 1993-11-04 | 1995-10-17 | Bristol-Myers Squibb Company | Process of preparing etoposide phosphate and etoposide |
| US6207673B1 (en) | 1997-03-12 | 2001-03-27 | The University Of North Carolina At Chapel Hill | Covalent conjugates of topoisomerase I and topoisomerase II inhibitors |
| US6051721A (en) * | 1997-10-02 | 2000-04-18 | The Board Of Regents Of The University Of Nebraska | Ring E-modified analogues of(-)-podophyllotoxin and etoposide and a method for their synthesis |
| WO2001024763A2 (en) | 1999-10-01 | 2001-04-12 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US608815A (en) * | 1898-08-09 | Wagon-pole coupling | ||
| GB823068A (en) * | 1955-05-13 | 1959-11-04 | Sandoz Ltd | Condensation products from glucosides |
| NL6613143A (pt) * | 1965-09-21 | 1967-03-22 | ||
| FR1518705A (fr) * | 1965-12-14 | 1968-03-29 | Sandoz Sa | Procédé de préparation d'un nouveau glucoside |
| CH464957A (de) * | 1965-12-14 | 1968-11-15 | Sandoz Ag | Verfahren zur Herstellung eines neuen Glucosids |
| US4547564A (en) * | 1982-12-27 | 1985-10-15 | General Electric Company | Polyester carbonate from branched chain alkylidene dihydric phenol |
| JPS6032799A (ja) * | 1983-07-29 | 1985-02-19 | Microbial Chem Res Found | 新規４′−デメチル−４−エピポドフィロトキシン誘導体 |
| JPS60246393A (ja) * | 1984-05-22 | 1985-12-06 | Nippon Kayaku Co Ltd | エトポシドの新規製造法 |
| US4609644A (en) * | 1984-06-15 | 1986-09-02 | St. Jude Children's Research Hospital | Epipodophyllotoxinquinone glucoside derivatives, method of production and use |
| US4853467A (en) * | 1987-05-19 | 1989-08-01 | Bristol-Myers Company | Nitrogen containing derivatives of epipodophyllotoxin glucosides |
| US4874851A (en) * | 1987-07-01 | 1989-10-17 | Bristol-Meyers Company | 3',4'-dinitrogen substituted epipodophyllotoxin glucoside derivatives |
-
1987
- 1987-08-31 US US07/091,570 patent/US4888419A/en not_active Expired - Fee Related
-
1988
- 1988-05-26 ZA ZA883763A patent/ZA883763B/xx unknown
- 1988-08-19 NZ NZ225879A patent/NZ225879A/en unknown
- 1988-08-26 FI FI883959A patent/FI88168C/fi not_active IP Right Cessation
- 1988-08-29 KR KR1019880011006A patent/KR900006236B1/ko not_active IP Right Cessation
- 1988-08-29 IL IL87586A patent/IL87586A/xx unknown
- 1988-08-30 DK DK482488A patent/DK482488A/da unknown
- 1988-08-30 PT PT88375A patent/PT88375B/pt not_active IP Right Cessation
- 1988-08-30 JP JP63216197A patent/JPS6471898A/ja active Granted
- 1988-08-30 EP EP88114141A patent/EP0305972A3/en not_active Withdrawn
- 1988-08-30 CA CA000576027A patent/CA1311472C/en not_active Expired - Fee Related
- 1988-08-30 NO NO883857A patent/NO168040C/no unknown
- 1988-08-30 AU AU21666/88A patent/AU620561B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU2166688A (en) | 1989-03-02 |
| FI883959A (fi) | 1989-03-01 |
| DK482488D0 (da) | 1988-08-30 |
| CA1311472C (en) | 1992-12-15 |
| NO168040C (no) | 1992-01-08 |
| KR890003793A (ko) | 1989-04-18 |
| KR900006236B1 (ko) | 1990-08-27 |
| AU620561B2 (en) | 1992-02-20 |
| NO168040B (no) | 1991-09-30 |
| FI883959A0 (fi) | 1988-08-26 |
| DK482488A (da) | 1989-03-01 |
| FI88168C (fi) | 1993-04-13 |
| ZA883763B (en) | 1989-10-25 |
| PT88375B (pt) | 1995-03-31 |
| NO883857D0 (no) | 1988-08-30 |
| NO883857L (no) | 1989-03-01 |
| JPH0453877B2 (pt) | 1992-08-27 |
| FI88168B (fi) | 1992-12-31 |
| IL87586A (en) | 1993-07-08 |
| EP0305972A2 (en) | 1989-03-08 |
| JPS6471898A (en) | 1989-03-16 |
| EP0305972A3 (en) | 1990-08-22 |
| US4888419A (en) | 1989-12-19 |
| NZ225879A (en) | 1991-04-26 |
| IL87586A0 (en) | 1989-01-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19940919 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19960331 |