ZA883763B - 3-demethoxyepipodophyllotoxin glucoside derivatives - Google Patents

3-demethoxyepipodophyllotoxin glucoside derivatives

Info

Publication number
ZA883763B
ZA883763B ZA883763A ZA883763A ZA883763B ZA 883763 B ZA883763 B ZA 883763B ZA 883763 A ZA883763 A ZA 883763A ZA 883763 A ZA883763 A ZA 883763A ZA 883763 B ZA883763 B ZA 883763B
Authority
ZA
South Africa
Prior art keywords
demethoxyepipodophyllotoxin
glucoside derivatives
glucoside
derivatives
demethoxyepipodophyllotoxin glucoside
Prior art date
Application number
ZA883763A
Other languages
English (en)
Inventor
Mark G Saulnier
G Saulnier Mark
Dolatrai M Vyas
M Vyas Dolatrai
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ZA883763B publication Critical patent/ZA883763B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA883763A 1987-08-31 1988-05-26 3-demethoxyepipodophyllotoxin glucoside derivatives ZA883763B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/091,570 US4888419A (en) 1987-08-31 1987-08-31 3'-demethoxyepipodophyllotoxin glucoside derivatives

Publications (1)

Publication Number Publication Date
ZA883763B true ZA883763B (en) 1989-10-25

Family

ID=22228465

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA883763A ZA883763B (en) 1987-08-31 1988-05-26 3-demethoxyepipodophyllotoxin glucoside derivatives

Country Status (13)

Country Link
US (1) US4888419A (xx)
EP (1) EP0305972A3 (xx)
JP (1) JPS6471898A (xx)
KR (1) KR900006236B1 (xx)
AU (1) AU620561B2 (xx)
CA (1) CA1311472C (xx)
DK (1) DK482488A (xx)
FI (1) FI88168C (xx)
IL (1) IL87586A (xx)
NO (1) NO168040C (xx)
NZ (1) NZ225879A (xx)
PT (1) PT88375B (xx)
ZA (1) ZA883763B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4853467A (en) * 1987-05-19 1989-08-01 Bristol-Myers Company Nitrogen containing derivatives of epipodophyllotoxin glucosides
US4965348A (en) * 1989-05-19 1990-10-23 Bristol-Myers Company Dimeric epipodophyllotoxin glucoside derivatives
US5036055A (en) * 1989-06-07 1991-07-30 Bristol-Myers Company Acylated derivatives of etoposide
US5081234A (en) * 1990-04-30 1992-01-14 Bristol-Myers Squibb Co. 4'-demethylepipodophyllotoxin glycosides
US5459248A (en) * 1993-11-04 1995-10-17 Bristol-Myers Squibb Company Process of preparing etoposide phosphate and etoposide
US6207673B1 (en) 1997-03-12 2001-03-27 The University Of North Carolina At Chapel Hill Covalent conjugates of topoisomerase I and topoisomerase II inhibitors
US6051721A (en) * 1997-10-02 2000-04-18 The Board Of Regents Of The University Of Nebraska Ring E-modified analogues of(-)-podophyllotoxin and etoposide and a method for their synthesis
CA2385528C (en) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US608815A (en) * 1898-08-09 Wagon-pole coupling
GB823068A (en) * 1955-05-13 1959-11-04 Sandoz Ltd Condensation products from glucosides
NL6613143A (xx) * 1965-09-21 1967-03-22
FR1518705A (fr) * 1965-12-14 1968-03-29 Sandoz Sa Procédé de préparation d'un nouveau glucoside
CH464957A (de) * 1965-12-14 1968-11-15 Sandoz Ag Verfahren zur Herstellung eines neuen Glucosids
US4547564A (en) * 1982-12-27 1985-10-15 General Electric Company Polyester carbonate from branched chain alkylidene dihydric phenol
JPS6032799A (ja) * 1983-07-29 1985-02-19 Microbial Chem Res Found 新規4′−デメチル−4−エピポドフィロトキシン誘導体
JPS60246393A (ja) * 1984-05-22 1985-12-06 Nippon Kayaku Co Ltd エトポシドの新規製造法
US4609644A (en) * 1984-06-15 1986-09-02 St. Jude Children's Research Hospital Epipodophyllotoxinquinone glucoside derivatives, method of production and use
US4853467A (en) * 1987-05-19 1989-08-01 Bristol-Myers Company Nitrogen containing derivatives of epipodophyllotoxin glucosides
US4874851A (en) * 1987-07-01 1989-10-17 Bristol-Meyers Company 3',4'-dinitrogen substituted epipodophyllotoxin glucoside derivatives

Also Published As

Publication number Publication date
KR890003793A (ko) 1989-04-18
CA1311472C (en) 1992-12-15
IL87586A (en) 1993-07-08
FI883959A0 (fi) 1988-08-26
FI883959A (fi) 1989-03-01
AU620561B2 (en) 1992-02-20
DK482488A (da) 1989-03-01
NO883857L (no) 1989-03-01
NO883857D0 (no) 1988-08-30
NO168040C (no) 1992-01-08
JPS6471898A (en) 1989-03-16
EP0305972A2 (en) 1989-03-08
FI88168C (fi) 1993-04-13
DK482488D0 (da) 1988-08-30
JPH0453877B2 (xx) 1992-08-27
NZ225879A (en) 1991-04-26
EP0305972A3 (en) 1990-08-22
AU2166688A (en) 1989-03-02
FI88168B (fi) 1992-12-31
PT88375B (pt) 1995-03-31
NO168040B (no) 1991-09-30
KR900006236B1 (ko) 1990-08-27
IL87586A0 (en) 1989-01-31
US4888419A (en) 1989-12-19
PT88375A (pt) 1989-06-30

Similar Documents

Publication Publication Date Title
GR3002864T3 (en) Azolylmethylcyclopropyl derivatives
YU234188A (en) Adenozine derivatives
ZA881835B (en) Avermectin derivatives
GB8815258D0 (en) Thiorea derivatives
EP0318704A3 (en) 3-cyano-4-phenyl-pyrrole derivatives
EP0305322A3 (en) Isoxazole-beta-carboline derivatives
ZA881808B (en) Propiolophenone derivatives
GR3000964T3 (en) Hydroxyethyl-azolyl derivatives
ZA883763B (en) 3-demethoxyepipodophyllotoxin glucoside derivatives
ZA885361B (en) Oligosaccharide derivatives
GB2205829B (en) 2-aryl-4-isoxazolin-3-one derivatives
EP0322164A3 (en) Ethanolamie derivatives
GB8705601D0 (en) Oxo-isoindolinyl derivatives
ZA888368B (en) 4-demethoxy anthracycline derivatives
GB2200910B (en) Thiopilocarpine derivatives
GB8704236D0 (en) Anthracycline-oestrone derivatives
GB8700016D0 (en) Quinolizinone derivatives
GB8715925D0 (en) Thiapentanamide derivatives
ZA884683B (en) Hydroxyethyl-azolyl derivatives
IE882630L (en) 3-demethoxyepipodophyllotoxin glucoside derivatives
GB2211840B (en) Indenofuran derivatives
GB8720380D0 (en) Tc-99m-labelled monosaccharide derivatives
FI103571B1 (fi) Propoksibentseenijohdannaisia
IE870414L (en) Furancarboxamide derivatives
IE871047L (en) Alkenamide derivatives