FI882248A - Nya benso(b) pyraner och pyranopyridiner, foerfarande foer deras framstaellning och anvaendning av desamma. - Google Patents

Nya benso(b) pyraner och pyranopyridiner, foerfarande foer deras framstaellning och anvaendning av desamma. Download PDF

Info

Publication number
FI882248A
FI882248A FI882248A FI882248A FI882248A FI 882248 A FI882248 A FI 882248A FI 882248 A FI882248 A FI 882248A FI 882248 A FI882248 A FI 882248A FI 882248 A FI882248 A FI 882248A
Authority
FI
Finland
Prior art keywords
och
pyranopyridiner
pyraner
desamma
benso
Prior art date
Application number
FI882248A
Other languages
English (en)
Finnish (fi)
Other versions
FI882248A0 (fi
Inventor
Stefan Blarer
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of FI882248A0 publication Critical patent/FI882248A0/fi
Publication of FI882248A publication Critical patent/FI882248A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/96Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI882248A 1987-05-16 1988-05-13 Nya benso(b) pyraner och pyranopyridiner, foerfarande foer deras framstaellning och anvaendning av desamma. FI882248A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3716523 1987-05-16

Publications (2)

Publication Number Publication Date
FI882248A0 FI882248A0 (fi) 1988-05-13
FI882248A true FI882248A (fi) 1988-11-17

Family

ID=6327752

Family Applications (1)

Application Number Title Priority Date Filing Date
FI882248A FI882248A (fi) 1987-05-16 1988-05-13 Nya benso(b) pyraner och pyranopyridiner, foerfarande foer deras framstaellning och anvaendning av desamma.

Country Status (21)

Country Link
US (1) US5071871A (sv)
JP (1) JPS63303977A (sv)
KR (1) KR880013915A (sv)
AT (1) ATA125188A (sv)
AU (1) AU614285B2 (sv)
BE (1) BE1002436A3 (sv)
CA (1) CA1312866C (sv)
CH (1) CH674984A5 (sv)
DK (1) DK265188A (sv)
ES (1) ES2012527A6 (sv)
FI (1) FI882248A (sv)
FR (1) FR2615191B1 (sv)
GB (1) GB2204868B (sv)
HU (1) HU203336B (sv)
IL (1) IL86376A0 (sv)
IT (1) IT1219940B (sv)
NL (1) NL8801258A (sv)
NZ (1) NZ224604A (sv)
PT (1) PT87492B (sv)
SE (1) SE467924B (sv)
ZA (1) ZA883450B (sv)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3835011A1 (de) * 1988-10-14 1990-04-19 Merck Patent Gmbh Chromanderivate
US5387587A (en) * 1986-12-23 1995-02-07 Merck Patent Gesellschaft Mit Beschrankter Haftung Chroman derivatives
US5284838A (en) * 1987-06-23 1994-02-08 Elf Sanofi Use of 2,2-dimethylchroman-3-ol derivatives in the treatment of asthma
US5021432A (en) * 1988-04-26 1991-06-04 Yoshitomi Pharmaceutical Industries, Ltd. Benzopyran compound and its pharmaceutical use
AU628331B2 (en) * 1988-05-06 1992-09-17 Merck Patent Gesellschaft Mit Beschrankter Haftung Chroman derivatives
EP0346724A1 (de) * 1988-06-16 1989-12-20 MERCK PATENT GmbH Chromanderivate
DE3837809A1 (de) * 1988-11-08 1990-05-10 Merck Patent Gmbh Tetralinderivate
FR2639349B1 (fr) * 1988-11-23 1991-02-22 Sanofi Sa Nouveaux derives du chromane actifs sur le systeme nerveux central, leur procede de preparation et les compositions pharmaceutiques en contenant
US5239090A (en) * 1989-02-01 1993-08-24 Beecham Group P.L.C. Certain optically active 3,4-dihydrobenzopyran-4-ols which are intermediates
GB8902118D0 (en) * 1989-02-01 1989-03-22 Beecham Group Plc Chemical process
US5066816A (en) * 1989-03-03 1991-11-19 Yoshitomi Pharmaceutical Industries, Ltd. Processes for preparing optically active 3,4-dihydro-3,4-epoxy-2h-1-benzopyran compounds and intermediates therefor
US5162553A (en) * 1989-03-03 1992-11-10 Yoshitomi Pharmaceutical Industries, Ltd. Processes for preparing optically active 3,4-dihydro-3,4-epoxy-2H-1-benzopyran compounds and intermediates therefor
GB8911949D0 (en) * 1989-05-24 1989-07-12 Beecham Group Plc Novel compounds
US5232938A (en) * 1989-05-24 1993-08-03 Beecham Group P.L.C. Certain 1,2,4-triazole(oxy or amino)benzopyran derivatives having pharmacological activity
DE3918041A1 (de) * 1989-06-02 1990-12-06 Merck Patent Gmbh Chromanderivate
GB8915315D0 (en) * 1989-07-04 1989-08-23 Sandoz Ltd Pharmaceutical compositions for use against hypertension and congestive heart failure
US5223629A (en) * 1989-07-21 1993-06-29 Alkaloida Vegyeszeti Gyar Process for the preparation of anti-hypertensive benzopyran
DE3924417A1 (de) * 1989-07-24 1991-01-31 Merck Patent Gmbh Chromanderivate
DE3926001A1 (de) * 1989-08-05 1991-02-07 Merck Patent Gmbh Chromanderivate
US5232944A (en) * 1989-10-09 1993-08-03 Merck Patent Gesellschaft Mit Beschrankter Haftung Chroman derivatives
DE3933663A1 (de) * 1989-10-09 1991-04-11 Merck Patent Gmbh Chromanderivate
GB8924373D0 (en) * 1989-10-30 1989-12-20 Beecham Group Plc Novel compounds
DE3936616A1 (de) * 1989-11-03 1991-05-08 Merck Patent Gmbh Verfahren zur enantiomerentrennung von benzopyranderivaten
GB2242628A (en) * 1990-04-06 1991-10-09 Sandoz Ltd Asthma prophylactic use of K+ channel activators
BE1004295A3 (fr) * 1990-05-17 1992-10-27 Sandoz Sa Utilisation des activateurs des canaux potassiques pour la prophylaxie de l'asthme.
DE4038752A1 (de) * 1990-12-05 1992-06-11 Merck Patent Gmbh Chromanderivate
JP3255411B2 (ja) * 1991-02-18 2002-02-12 中外製薬株式会社 発毛促進剤
US5291890A (en) * 1991-08-29 1994-03-08 General Electric Company Magnetic resonance surgery using heat waves produced with focussed ultrasound
US5206252A (en) * 1992-05-08 1993-04-27 American Home Products Corporation Thiadiazolyl-amino derivatives of benzopyrans and indanes
TW258735B (sv) * 1992-08-17 1995-10-01 Chugai Pharmaceutical Co Ltd
PL177516B1 (pl) * 1993-08-19 1999-12-31 Janssen Pharmaceutica Nv Nowy związek,pochodna dihydropiranopirydyny o właściwościach naczyniozwężających, środek farmaceutyczny i sposób wytwarzania pochodnej dihydropiranopirydyny
US5368031A (en) * 1993-08-29 1994-11-29 General Electric Company Magnetic resonance surgery using heat waves produced with a laser fiber
US5837702A (en) * 1993-10-07 1998-11-17 Bristol-Myers Squibb Co. 4-arylamino-benzopyran and related compounds
EP0677519A4 (en) * 1993-11-10 1996-04-03 Japan Tobacco Inc CHROMAN DERIVATIVE AND THERAPEUTIC USE THEREOF.
US5482942A (en) * 1994-06-28 1996-01-09 American Home Products Corporation (3,4-dioxocyclobuten-1-yl)chromene, indene, and dihydronaphthalenone derivatives as smooth muscle relaxants
US5470861A (en) * 1994-08-04 1995-11-28 Hoffmann-La Roche Inc. Method of promoting hair growth
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives
US5629429A (en) * 1995-06-07 1997-05-13 Bristol-Myers Squibb Company Process for preparing 4-arylamino-benzopyran and related compounds
US5612323A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phosphinic ester substituted benzopyran derivatives
AU7319800A (en) * 1999-09-24 2001-04-24 Nissan Chemical Industries Ltd. 4-oxybenzopyran derivative
US6677371B1 (en) 1999-10-05 2004-01-13 Nissan Chemical Industries, Ltd. 4-oxybenzopyran derivative
US20110136898A1 (en) * 2008-08-05 2011-06-09 University College Cork, National University Of Ireland, Cork Treatment of retinal degeneration

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4391815A (en) * 1976-04-02 1983-07-05 Beecham Group Limited Cyanobenzano[b]pyrans
FI79535C (sv) * 1982-05-06 1990-01-10 Erba Farmitalia Förfarande för framställning av dihydrobensopyrans och dihydrobensotio pyrans substituerade iminoderivat
DE3364734D1 (en) * 1982-10-19 1986-08-28 Beecham Group Plc Novel chromans and chromenes
GB8308062D0 (en) * 1983-03-24 1983-05-05 Beecham Group Plc Active compounds
GB8308063D0 (en) * 1983-03-24 1983-05-05 Beecham Group Plc Active compounds
DE3682331D1 (de) * 1985-06-08 1991-12-12 Beecham Group Plc Pyrano(3,2-c)pyridinderivate, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen.
DE3732146A1 (de) * 1987-09-24 1989-04-06 Merck Patent Gmbh Azachromanderivate
AU621578B2 (en) * 1987-12-22 1992-03-19 Suntory Limited Novel compound effective as cerebral insufficiency improver

Also Published As

Publication number Publication date
DK265188D0 (da) 1988-05-13
GB8811359D0 (en) 1988-06-15
NL8801258A (nl) 1988-12-16
KR880013915A (ko) 1988-12-22
BE1002436A3 (fr) 1991-02-12
CA1312866C (en) 1993-01-19
US5071871A (en) 1991-12-10
ES2012527A6 (es) 1990-04-01
SE8801807D0 (sv) 1988-05-13
JPS63303977A (ja) 1988-12-12
GB2204868B (en) 1991-05-22
IL86376A0 (en) 1988-11-15
PT87492A (pt) 1989-05-31
HUT50151A (en) 1989-12-28
HU203336B (en) 1991-07-29
DK265188A (da) 1988-11-17
CH674984A5 (sv) 1990-08-15
ATA125188A (de) 1993-06-15
FI882248A0 (fi) 1988-05-13
GB2204868A (en) 1988-11-23
IT8847956A0 (it) 1988-05-13
FR2615191A1 (fr) 1988-11-18
IT1219940B (it) 1990-05-24
PT87492B (pt) 1992-09-30
AU614285B2 (en) 1991-08-29
AU1615888A (en) 1988-11-17
NZ224604A (en) 1991-04-26
SE8801807L (sv) 1988-11-17
SE467924B (sv) 1992-10-05
ZA883450B (en) 1990-01-31
FR2615191B1 (fr) 1991-01-11

Similar Documents

Publication Publication Date Title
FI882248A0 (fi) Nya benso(b) pyraner och pyranopyridiner, foerfarande foer deras framstaellning och anvaendning av desamma.
FI883129A0 (fi) Foerfarande foer framstaellning av organiserade strukturer av kollagen, speciellt av maenskligt ursprung och motsvarande organiserade strukturer av kollagen.
FI872841A0 (fi) Nya kromoforfoereningar, solskyddskompositioner och foerfarande foer hindrande av solbraenna.
FI872965A0 (fi) Foerfarande och anordning foer kapning av papper, isynnerhet foerperforerat papper.
FI883347A (fi) Nya 5-aminometylen-2,4 -imidazolidindioner och 5-aminometylen-4-tionoimidazolidin-4-oner.
FI882993A (fi) Silikapartiklar, saett foer framstaellning av silikapartiklar och anvaendning av dessa.
FI872147A0 (fi) Fiskfoder, foerfarande foer framstaellning av detsamma och utfodringsfoerfarande.
FI885766A0 (fi) Nya derivat av cykliska aminosyror, foerfarande foer deras framstaellning, dessa innehaollande aemnen och deras anvaendning.
FI893142A0 (fi) Nya aromoljor av minttyp, foerfarande foer framstaellning av desamma, och kompositioner innehaollande desamma.
FI885056A (fi) Nya fluormetoxifenyldihydropyridiner, foerfarande foer deras framstaellning och deras anvaendning i laekemedel.
FI883200A (fi) Foerfarande, anordning och tillbehoer foer maetning av vaevnadsplasminogenaktivator-aktivitet.
FI885722A (fi) Nya kinolinderivat, foerfaranden foer framstaellning daerav och antibakteriella aemnen innehaollande desamma.
FI884225A0 (fi) Nya aminosyraestrar, foerfaranden foer deras framstaellning, dessa innehaollande laekemedel och deras anvaendning.
FI882475A0 (fi) Framstaellningsfoerfarande av nya 5-( -ammonioacyloximetylen) tetrahydrofuraner och tetrahydrotiofener.
FI882180A0 (fi) Nya alkylerade vaexthormoner frigoerande peptider och foerfarande foer behandling av daeggdjur medelst hjaelp av dessa.
FI875327A (fi) Foerfarande och anordning foer framstaellning av betongstomelement, isynnerhet bjaelkar.
FI885057A0 (fi) Nya fluormetoxifenyldihydropyridiner, foerfaranden foer deras framstaellning och deras anvaendning i laekemedel.
FI875168A0 (fi) Foerfarande foer framstaellning av nya rodiumhydreringskatalysatorer och anvaendning av dessa.
FI873317A0 (fi) Foerfarande och anordning foer bestrykning av laongstraeckta staolstycken, isynnerhet betongstaol och staolprofiler.
FI881471A (fi) Nya alkansyraalkylestrar, foerfarande foer deras framstaellning och anvaendning av vattenhaltiga emulsioner av dessa i vacciner.
FI872588A0 (fi) Foerfarande, saendare och mottagare foer oeverfoerande av digitalisk tillaeggsinformation.
FI872724A (fi) Cellplast, foerfarande foer framstaellning av cellplast och anvaendningen av cellplast.
FI881909A (fi) Nitrosoureaderivator, deras framstaellning och anvaendning av desamma.
FI874133A (fi) Foerfarande och anordning foer framstaellning av betongstomelement, isynnerhet bjaelkar.
FI872498A0 (fi) Foerfarande, glidgjutningsanordning och armering foer gjutning av konstruktionen.

Legal Events

Date Code Title Description
FD Application lapsed
MM Patent lapsed

Owner name: SANDOZ AG