FI880387A - 1-(4-hydroxi-3,5-di-tert -butylbenzoyl) homopiperazin, dess olika derivat, foerfarande foer framstaellning av dessa foereningar, dessa innehaollande laekemdel och deras anvaendning. - Google Patents
1-(4-hydroxi-3,5-di-tert -butylbenzoyl) homopiperazin, dess olika derivat, foerfarande foer framstaellning av dessa foereningar, dessa innehaollande laekemdel och deras anvaendning. Download PDFInfo
- Publication number
- FI880387A FI880387A FI880387A FI880387A FI880387A FI 880387 A FI880387 A FI 880387A FI 880387 A FI880387 A FI 880387A FI 880387 A FI880387 A FI 880387A FI 880387 A FI880387 A FI 880387A
- Authority
- FI
- Finland
- Prior art keywords
- dessa
- homopiperazine
- tert
- hydroxy
- butylbenzoyl
- Prior art date
Links
- FQUYSHZXSKYCSY-UHFFFAOYSA-N 1,4-diazepane Chemical compound C1CNCCNC1 FQUYSHZXSKYCSY-UHFFFAOYSA-N 0.000 title abstract 2
- -1 4-HYDROXY-3,5-DI-TERT-BUTYLBENZOYL Chemical class 0.000 title 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 230000002757 inflammatory effect Effects 0.000 abstract 2
- LYRRSBJFMOFHBF-UHFFFAOYSA-N 1,4-diazepan-1-yl-(3,5-ditert-butyl-4-hydroxyphenyl)methanone Chemical compound CC(C)(C)C1=C(O)C(C(C)(C)C)=CC(C(=O)N2CCNCCC2)=C1 LYRRSBJFMOFHBF-UHFFFAOYSA-N 0.000 abstract 1
- 208000025747 Rheumatic disease Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 230000000552 rheumatic effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Lubricants (AREA)
- Polyesters Or Polycarbonates (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3702755 | 1987-01-30 | ||
DE19873702755 DE3702755A1 (de) | 1987-01-30 | 1987-01-30 | 3,5-di-tert.-butyl-4-hydroxybenzoesaeureamid, verschiedene von dessen derivaten, verfahren zur herstellung dieser verbindungen, die sie enthaltenden arzneimittel und ihre verwendung |
Publications (4)
Publication Number | Publication Date |
---|---|
FI880387A0 FI880387A0 (fi) | 1988-01-28 |
FI880387A true FI880387A (fi) | 1988-07-31 |
FI85469B FI85469B (fi) | 1992-01-15 |
FI85469C FI85469C (fi) | 1992-04-27 |
Family
ID=6319853
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI880387A FI85469C (fi) | 1987-01-30 | 1988-01-28 | Foerfarande foer framstaellning av terapeutiskt anvaendbara 1-(4-hydroxi-3,5-di-tert -butylbenzoyl) homopiperazinderivat. |
Country Status (20)
Country | Link |
---|---|
US (1) | US4829061A (fi) |
EP (1) | EP0276803B1 (fi) |
JP (1) | JPS63192758A (fi) |
KR (1) | KR880008997A (fi) |
AT (1) | ATE68488T1 (fi) |
AU (1) | AU600793B2 (fi) |
CA (1) | CA1300619C (fi) |
DE (2) | DE3702755A1 (fi) |
DK (1) | DK47888A (fi) |
ES (1) | ES2041705T3 (fi) |
FI (1) | FI85469C (fi) |
GR (1) | GR3003523T3 (fi) |
HU (1) | HU200334B (fi) |
IE (1) | IE880249L (fi) |
IL (1) | IL85228A (fi) |
NO (1) | NO170332C (fi) |
NZ (1) | NZ223336A (fi) |
PH (1) | PH24649A (fi) |
PT (1) | PT86657B (fi) |
ZA (1) | ZA88642B (fi) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE951044C (de) * | 1954-08-24 | 1956-10-18 | Heinrich Gueltig | Verfahren zum UEberziehen zugeschnittener Flaschenkorken mit einem mindestens vorwiegend Paraffin enthaltenden UEberzug |
DE3834532A1 (de) * | 1988-10-11 | 1990-04-12 | Behringwerke Ag | Verwendung von homopiperazinen zur herstellung eines arzneimittels fuer das vorbeugen gegen und die behandlung von organabstossungsreaktionen |
US5281623A (en) * | 1990-08-27 | 1994-01-25 | Eli Lilly And Company | Method for treating inflammation |
CA2049481A1 (en) * | 1990-08-27 | 1992-02-28 | Jill Ann Panetta | Method of treating inflammatory bowel disease |
US5280046A (en) * | 1991-02-22 | 1994-01-18 | The University Of Colorado Foundation, Inc. | Method of treating type I diabetes |
JP3497164B2 (ja) * | 1991-06-28 | 2004-02-16 | スミスクライン・ビーチャム・コーポレイション | 二環式フィブリノーゲン拮抗薬 |
US5939412A (en) * | 1992-06-26 | 1999-08-17 | Smithkline Beecham Corporation | Bicyclic fibrinogen antagonists |
CA2152631A1 (en) * | 1992-12-21 | 1994-07-07 | William Edward Bondinell | Bicyclic fibrinogen antagonists |
US6403578B1 (en) | 1993-12-21 | 2002-06-11 | Smithkline Beecham Corporation | Bicyclic fibrinogen antagonists |
MA23420A1 (fr) * | 1994-01-07 | 1995-10-01 | Smithkline Beecham Corp | Antagonistes bicycliques de fibrinogene. |
US6458784B1 (en) | 1994-06-29 | 2002-10-01 | Smithkline Beecham Corporation | Vitronectin receptor antagonists |
US5977101A (en) * | 1995-06-29 | 1999-11-02 | Smithkline Beecham Corporation | Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity |
DE19737334A1 (de) * | 1997-08-27 | 1999-03-04 | Solvay Pharm Gmbh | 7-Phenyl-1,4-diazepan-Derivate, sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
DE19747644C2 (de) * | 1997-10-29 | 2001-02-22 | Inst Polymerforschung Dresden | Sterisch gehinderte Phenole und Verfahren zu ihrer Herstellung |
WO2002080928A1 (en) * | 2001-04-03 | 2002-10-17 | Merck & Co., Inc. | N-substituted nonaryl-heterocyclo amidyl nmda/nr2b antagonists |
EP2583678A3 (en) | 2004-06-24 | 2013-11-13 | Novartis Vaccines and Diagnostics, Inc. | Small molecule immunopotentiators and assays for their detection |
US10449198B2 (en) | 2016-07-01 | 2019-10-22 | The University Of Liverpool | Method for treating pain |
JP2021500416A (ja) * | 2017-10-27 | 2021-01-07 | エステベ ファーマスーティカルズ,ソシエダッド アノニマ | 疼痛及び疼痛関連状態を治療するための新規アルコキシアミノ誘導体 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4066614A (en) * | 1974-12-30 | 1978-01-03 | American Cyanamid Company | Heterocyclicamides of hindered 3,5-dialkyl-4-hydroxybenzoic acids and use as light stabilizers in polyolefins |
US4404302A (en) * | 1982-05-27 | 1983-09-13 | Ferro Corporation | Acylated hindered hexahydropyrimidines and their use as light stabilizing agents |
EP0190685B1 (en) * | 1985-02-04 | 1992-07-01 | G.D. Searle & Co. | Heterocyclic amides |
-
1987
- 1987-01-30 DE DE19873702755 patent/DE3702755A1/de not_active Withdrawn
-
1988
- 1988-01-26 AT AT88101054T patent/ATE68488T1/de not_active IP Right Cessation
- 1988-01-26 ES ES198888101054T patent/ES2041705T3/es not_active Expired - Lifetime
- 1988-01-26 EP EP88101054A patent/EP0276803B1/de not_active Expired - Lifetime
- 1988-01-26 DE DE8888101054T patent/DE3865443D1/de not_active Expired - Fee Related
- 1988-01-28 FI FI880387A patent/FI85469C/fi not_active IP Right Cessation
- 1988-01-28 PT PT86657A patent/PT86657B/pt active IP Right Grant
- 1988-01-28 HU HU88390A patent/HU200334B/hu not_active IP Right Cessation
- 1988-01-28 NZ NZ223336A patent/NZ223336A/xx unknown
- 1988-01-28 IL IL85228A patent/IL85228A/xx not_active IP Right Cessation
- 1988-01-28 US US07/149,602 patent/US4829061A/en not_active Expired - Fee Related
- 1988-01-29 NO NO880407A patent/NO170332C/no unknown
- 1988-01-29 KR KR1019880000766A patent/KR880008997A/ko not_active Application Discontinuation
- 1988-01-29 IE IE880249A patent/IE880249L/xx unknown
- 1988-01-29 CA CA000557741A patent/CA1300619C/en not_active Expired - Fee Related
- 1988-01-29 ZA ZA88642A patent/ZA88642B/xx unknown
- 1988-01-29 DK DK047888A patent/DK47888A/da not_active Application Discontinuation
- 1988-01-29 AU AU10999/88A patent/AU600793B2/en not_active Ceased
- 1988-01-29 JP JP63017514A patent/JPS63192758A/ja active Pending
- 1988-01-29 PH PH36433A patent/PH24649A/en unknown
-
1992
- 1992-01-08 GR GR910401655T patent/GR3003523T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
NO170332B (no) | 1992-06-29 |
EP0276803B1 (de) | 1991-10-16 |
IL85228A (en) | 1993-08-18 |
HUT46683A (en) | 1988-11-28 |
KR880008997A (ko) | 1988-09-13 |
PH24649A (en) | 1990-09-07 |
DK47888A (da) | 1988-07-31 |
PT86657B (pt) | 1992-02-28 |
IL85228A0 (en) | 1988-07-31 |
DE3865443D1 (de) | 1991-11-21 |
NO170332C (no) | 1992-10-07 |
PT86657A (pt) | 1988-02-01 |
FI85469C (fi) | 1992-04-27 |
DE3702755A1 (de) | 1988-08-11 |
GR3003523T3 (fi) | 1993-03-16 |
IE880249L (en) | 1988-07-30 |
DK47888D0 (da) | 1988-01-29 |
AU1099988A (en) | 1988-08-04 |
US4829061A (en) | 1989-05-09 |
CA1300619C (en) | 1992-05-12 |
NO880407L (no) | 1988-08-01 |
NZ223336A (en) | 1989-09-27 |
FI880387A0 (fi) | 1988-01-28 |
ZA88642B (en) | 1988-09-28 |
JPS63192758A (ja) | 1988-08-10 |
NO880407D0 (no) | 1988-01-29 |
FI85469B (fi) | 1992-01-15 |
HU200334B (en) | 1990-05-28 |
ES2041705T3 (es) | 1993-12-01 |
AU600793B2 (en) | 1990-08-23 |
ATE68488T1 (de) | 1991-11-15 |
EP0276803A1 (de) | 1988-08-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM | Patent lapsed | ||
MM | Patent lapsed |
Owner name: HOECHST AKTIENGESELLSCHAFT |