DE69326149D1 - (3R,4R)--g(D)?6-TETRAHYDROCANNABINOL-7-CARBONSÄUREN - Google Patents

(3R,4R)--g(D)?6-TETRAHYDROCANNABINOL-7-CARBONSÄUREN

Info

Publication number
DE69326149D1
DE69326149D1 DE69326149T DE69326149T DE69326149D1 DE 69326149 D1 DE69326149 D1 DE 69326149D1 DE 69326149 T DE69326149 T DE 69326149T DE 69326149 T DE69326149 T DE 69326149T DE 69326149 D1 DE69326149 D1 DE 69326149D1
Authority
DE
Germany
Prior art keywords
tetrahydrocannabinol
carbonic acids
carbonic
acids
thc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69326149T
Other languages
English (en)
Other versions
DE69326149T2 (de
Inventor
Sumner Burstein
Raphael Mechoulam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE69326149D1 publication Critical patent/DE69326149D1/de
Publication of DE69326149T2 publication Critical patent/DE69326149T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Tires In General (AREA)
  • Glass Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69326149T 1992-07-14 1993-07-13 (3R,4R)--g(D)?6-TETRAHYDROCANNABINOL-7-CARBONSÄUREN Expired - Fee Related DE69326149T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/913,096 US5338753A (en) 1992-07-14 1992-07-14 (3R,4R)-Δ6 -tetrahydrocannabinol-7-oic acids useful as antiinflammatory agents and analgesics
PCT/US1993/006580 WO1994001429A1 (en) 1992-07-14 1993-07-13 (3r,4r)-δ6-tetrahydrocannabinol-7-oic acids

Publications (2)

Publication Number Publication Date
DE69326149D1 true DE69326149D1 (de) 1999-09-30
DE69326149T2 DE69326149T2 (de) 2000-04-27

Family

ID=25432922

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69326149T Expired - Fee Related DE69326149T2 (de) 1992-07-14 1993-07-13 (3R,4R)--g(D)?6-TETRAHYDROCANNABINOL-7-CARBONSÄUREN

Country Status (13)

Country Link
US (1) US5338753A (de)
EP (1) EP0650483B1 (de)
JP (1) JP3278159B2 (de)
KR (1) KR100289202B1 (de)
AT (1) ATE183744T1 (de)
AU (1) AU676845B2 (de)
CA (1) CA2140368C (de)
DE (1) DE69326149T2 (de)
DK (1) DK0650483T3 (de)
ES (1) ES2138626T3 (de)
GR (1) GR3031966T3 (de)
HK (1) HK1010690A1 (de)
WO (1) WO1994001429A1 (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5635530A (en) * 1991-09-12 1997-06-03 Yissum Research Development Company Of The Hebrew University Of Jerusalem (3S,4S)-delta-6-tetrahydrocannabinol-7-oic acids and derivatives thereof, processors for their preparation and pharmaceutical compositions containing them
IL115245A (en) * 1995-09-11 2002-12-01 Yissum Res Dev Co Tumor necrosis factor inhibiting pharmaceuticals
US6132762A (en) * 1997-05-05 2000-10-17 Cristobal; Walter Transcutaneous application of marijuana
US6162829A (en) * 1997-10-17 2000-12-19 Atlantic Pharmaceuticals, Inc. (3R,4R)-Δ8 -tetrahydrocannabinol-11-oic acids useful as antiinflammatory agents and analgesics
GB9807639D0 (en) * 1998-04-14 1998-06-10 Kennedy Rheumatology Inst Anti-inflammatory agents
US5847128A (en) * 1998-05-29 1998-12-08 Virginia Commonwealth University Water soluble derivatives of cannabinoids
US6274635B1 (en) 1999-03-22 2001-08-14 Immugen Pharmaceuticals Inc. Alkylated resorcinol derivatives for the treatment of immune diseases
US6566560B2 (en) 1999-03-22 2003-05-20 Immugen Pharmaceuticals, Inc. Resorcinolic compounds
US6448288B1 (en) 2000-05-17 2002-09-10 University Of Massachusetts Cannabinoid drugs
WO2002026224A2 (en) * 2000-09-28 2002-04-04 Immugen Pharmaceuticals, Inc. Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
US6541510B2 (en) * 2000-09-28 2003-04-01 Immugen Pharmaceuticals, Inc. Antiviral methods and compounds
US7507767B2 (en) * 2001-02-08 2009-03-24 Schering Corporation Cannabinoid receptor ligands
US7067539B2 (en) * 2001-02-08 2006-06-27 Schering Corporation Cannabinoid receptor ligands
AU2002318427A1 (en) * 2001-06-25 2003-03-03 University Of Massachusetts N-fatty acid-amino acid conjugates and therapeutic uses
EP2147679B1 (de) 2001-07-25 2014-06-25 Raptor Pharmaceutical, Inc. Zusammensetzungen für den Blut-Hirn-Schrankentransport
US7071213B2 (en) 2001-11-14 2006-07-04 Schering Corporation Cannabinoid receptor ligands
ES2333214T3 (es) 2002-02-19 2010-02-18 SHIONOGI & CO., LTD. Antipruriticos.
CN1652766A (zh) * 2002-03-18 2005-08-10 免疫力药品有限公司 间苯二酚和大麻素的局部制剂及其施用方法
US7217732B2 (en) 2002-06-19 2007-05-15 Schering Corporation Cannabinoid receptor agonists
ATE433956T1 (de) 2002-11-25 2009-07-15 Schering Corp Cannabinoid-rezeptorliganden
US20040186166A1 (en) * 2002-12-19 2004-09-23 Burstein Sumner H. Cannabinoid analogs as peroxisome proliferator activated nuclear receptor gamma activators
TW200505902A (en) 2003-03-20 2005-02-16 Schering Corp Cannabinoid receptor ligands
US20050070596A1 (en) * 2003-05-12 2005-03-31 David Baker Methods for treatment of inflammatory diseases using CT-3 or analogs thereof
US6916852B2 (en) * 2003-05-12 2005-07-12 University Of Tennessee Research Foundation Method for regulation of microvascular tone
EP2259050A3 (de) * 2003-08-26 2010-12-22 Blueshift Biotechnologies, Inc. Zeitabhängige Fluoreszenzmessungen
US20050264805A1 (en) * 2004-02-09 2005-12-01 Blueshift Biotechnologies, Inc. Methods and apparatus for scanning small sample volumes
JP2008503585A (ja) * 2004-06-22 2008-02-07 シェーリング　コーポレイション カンナビノイドレセプターリガンド
WO2006014351A2 (en) 2004-07-02 2006-02-09 Blueshift Biotechnologies, Inc. Exploring fluorophore microenvironments
US7544714B2 (en) * 2004-07-16 2009-06-09 University Of Massachusetts Lipid-amino acid conjugates and methods of use
WO2006065793A2 (en) * 2004-12-13 2006-06-22 Indevus Pharmaceuticals, Inc. TREATMENT OF INTERSTITIAL CYSTITIS USING (6aR,10aR)-Δ8-TETRAHYDROCANNABINOL-11-OIC ACIDS
US20060128738A1 (en) * 2004-12-13 2006-06-15 Indevus Pharmaceuticals, Inc. Treatment of interstitial cystitis using cannabinoid analogs
WO2006116718A2 (en) 2005-04-28 2006-11-02 Proteus Biomedical, Inc. Pharma-informatics system
TWI366460B (en) 2005-06-16 2012-06-21 Euro Celtique Sa Cannabinoid active pharmaceutical ingredient for improved dosage forms
US20070037873A1 (en) * 2005-08-08 2007-02-15 Zurier Robert B Airway remodeling treatments
EP2578561A1 (de) 2005-09-29 2013-04-10 Albany Molecular Research, Inc. Verfahren zur Herstellung von Cannavbidiolderivaten und deren Intermediaten
WO2007047010A2 (en) * 2005-10-20 2007-04-26 Indevus Pharmaceuticals, Inc. Anti-emetic uses of cannabinoid analogs
WO2007055806A1 (en) * 2005-10-31 2007-05-18 Indevus Pharmaceuticals, Inc. Anti-emetic uses of (3r,4r)-δ8-tetrahydrocannabinol-11-oic acids
US8795627B2 (en) 2007-03-21 2014-08-05 Raptor Pharmaceuticals Inc. Treatment of liver disorders by administration of RAP conjugates
JP5564517B2 (ja) 2009-02-20 2014-07-30 ティーオー − ビービービー ホールディング ベスローテン フェンノートシャップ グルタチオンをベースとする薬物送達システム
CN102458374A (zh) 2009-05-06 2012-05-16 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其使用方法
US9066910B2 (en) * 2010-04-15 2015-06-30 Steven Rosenblatt Methods and compositions of cannabis extracts
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
EP3851101A1 (de) 2013-02-12 2021-07-21 Corbus Pharmaceuticals, Inc. Ultrareine tetrahydrocannabinol-11-on-säuren
US9585867B2 (en) 2015-08-06 2017-03-07 Charles Everett Ankner Cannabinod formulation for the sedation of a human or animal
US10239808B1 (en) 2016-12-07 2019-03-26 Canopy Holdings, LLC Cannabis extracts
WO2019152736A1 (en) 2018-01-31 2019-08-08 Canopy Holdings, LLC Hemp powder
CA3119729A1 (en) 2018-10-10 2020-04-16 Treehouse Biotech, Inc. Synthesis of cannabigerol
EP4017485A1 (de) 2019-08-22 2022-06-29 EPM Group, Inc. Cannabidiolsäureesterzusammensetzungen und verwendungen davon
CA3154437A1 (en) * 2019-10-11 2021-04-15 Corbus Pharmaceuticals, Inc. Compositions of ajulemic acid and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4973603A (en) * 1988-06-16 1990-11-27 Sumner Burstein Platelet activating factor antagonist and methods of use therefor
IL99468A (en) * 1991-09-12 1997-09-30 Yissum Res Dev Co (3s, 4s)-delta- 6-tetrahydrocannabinol- 7-oic acids and derivatives thereof, processes for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
ES2138626T3 (es) 2000-01-16
EP0650483A1 (de) 1995-05-03
ATE183744T1 (de) 1999-09-15
EP0650483B1 (de) 1999-08-25
US5338753A (en) 1994-08-16
KR100289202B1 (ko) 2001-05-02
WO1994001429A1 (en) 1994-01-20
DE69326149T2 (de) 2000-04-27
JP3278159B2 (ja) 2002-04-30
HK1010690A1 (en) 1999-06-25
DK0650483T3 (da) 2000-03-27
CA2140368C (en) 2004-04-27
GR3031966T3 (en) 2000-03-31
KR950702549A (ko) 1995-07-29
EP0650483A4 (en) 1995-05-10
AU676845B2 (en) 1997-03-27
CA2140368A1 (en) 1994-01-20
JPH08500096A (ja) 1996-01-09
AU4675993A (en) 1994-01-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee