FI875598A - 8-substituerade 2-aminotetraliner. - Google Patents

8-substituerade 2-aminotetraliner. Download PDF

Info

Publication number
FI875598A
FI875598A FI875598A FI875598A FI875598A FI 875598 A FI875598 A FI 875598A FI 875598 A FI875598 A FI 875598A FI 875598 A FI875598 A FI 875598A FI 875598 A FI875598 A FI 875598A
Authority
FI
Finland
Prior art keywords
aminotetraliner
substituerade
Prior art date
Application number
FI875598A
Other languages
English (en)
Finnish (fi)
Other versions
FI875598A0 (fi
Inventor
Bodo Junge
Bernd Richter
Thomas Glaser
Joerg Traber
George S Allen
Original Assignee
Troponwerke Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Troponwerke Gmbh & Co Kg filed Critical Troponwerke Gmbh & Co Kg
Publication of FI875598A0 publication Critical patent/FI875598A0/fi
Publication of FI875598A publication Critical patent/FI875598A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/16—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings other than six-membered aromatic rings
    • C07C211/19—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings other than six-membered aromatic rings containing condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI875598A 1986-12-22 1987-12-18 8-substituerade 2-aminotetraliner. FI875598A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3643899 1986-12-22
DE19873719924 DE3719924A1 (de) 1986-12-22 1987-06-15 8-substituierte 2-aminotetraline

Publications (2)

Publication Number Publication Date
FI875598A0 FI875598A0 (fi) 1987-12-18
FI875598A true FI875598A (fi) 1988-06-23

Family

ID=25850693

Family Applications (1)

Application Number Title Priority Date Filing Date
FI875598A FI875598A (fi) 1986-12-22 1987-12-18 8-substituerade 2-aminotetraliner.

Country Status (14)

Country Link
US (3) US4873262A (hu)
EP (1) EP0272534A3 (hu)
JP (1) JP2596956B2 (hu)
KR (1) KR880007432A (hu)
CN (1) CN87101285A (hu)
AU (1) AU613884B2 (hu)
DE (1) DE3719924A1 (hu)
DK (1) DK675787A (hu)
FI (1) FI875598A (hu)
HU (1) HUT46653A (hu)
IL (1) IL84875A0 (hu)
NO (1) NO167282C (hu)
NZ (1) NZ222977A (hu)
PT (1) PT86425B (hu)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5177112A (en) * 1983-01-03 1993-01-05 Whitby Research, Inc. Substituted 2-aminotetralins
DE3718317A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte basische 2-aminotetraline
US4927955A (en) * 1987-08-12 1990-05-22 Sanofi Process for the O-alkylation of N-(hydroxy)aralkylphenylethanolamines
DE3809155A1 (de) * 1988-03-18 1989-09-28 Bayer Ag 1,3,4,5-tetrahydrobenz-(c,d)-indole
CA1331191C (en) 1988-03-25 1994-08-02 Bengt Ronny Andersson Therapeutically useful tetralin derivatives
US5214156A (en) * 1988-03-25 1993-05-25 The Upjohn Company Therapeutically useful tetralin derivatives
US5162375A (en) * 1988-05-06 1992-11-10 Beecham Group P.L.C. Treatment of neuronal degeneration with 5HT1A agonists
GB8810748D0 (en) * 1988-05-06 1988-06-08 Beecham Wuelfing Gmbh & Co Kg Novel treatment
KR910700225A (ko) * 1989-01-09 1991-03-14 로버트 에이. 아미테이지 할로 치환된 아미노테트랄린
US5225596A (en) * 1989-01-09 1993-07-06 The Upjohn Company Halo substituted aminotetralins
CA1335106C (en) * 1989-02-27 1995-04-04 John Mehnert Schaus Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes
IL109647A (en) * 1989-02-27 1997-04-15 Lilly Co Eli Intermediate compounds for ring-substituted 2-amino-1, 2, 3, 4-tetra- hydronaphthalenes and 3-aminochromanes
GB8907865D0 (en) * 1989-04-07 1989-05-24 Wyeth John & Brother Ltd Tetrahydroquinoline derivatives
SE8901889D0 (sv) * 1989-05-26 1989-05-26 Astra Ab Novel 8-substituted-2-aminotetralines
HUT61719A (en) * 1989-05-31 1993-03-01 Upjohn Co Process for producing 2-aminotetraline derivatives and pharmaceutical compositions comprising such compounds
US5545755A (en) * 1989-05-31 1996-08-13 The Upjohn Company Therapeutically useful 2-aminotetralin derivatives
DE3919624A1 (de) * 1989-06-15 1990-12-20 Boehringer Ingelheim Kg Neue 2,5-diaminotetraline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US5486611A (en) * 1989-07-13 1996-01-23 The Upjohn Company Carboxamido-(1,2N)-carbocyclic-2-aminotetralin derivatives
DK0482084T3 (da) * 1989-07-13 1997-11-03 Upjohn Co (1,2N)- og (3,2N)-carbocyklisk-2-amino-tetralin-derivater.
DE3924365A1 (de) * 1989-07-22 1991-01-24 Boehringer Ingelheim Kg 2-amino-7-carbamoyl-1,2,3,4- tetrahydronaphthaline, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US5616610A (en) * 1989-12-22 1997-04-01 Astra Aktiebolag (R)-5-carbamoyl-8-fluoro-3-N,N-disubstituted-amino-3,4-dihydro-2H-1-benzopyrans
US5420151A (en) * 1989-12-22 1995-05-30 Aktiebolaget Astra Chroman derivatives
CA2071897A1 (en) * 1989-12-28 1991-06-29 Richard A. Glennon Sigma receptor ligands and the use thereof
HUT57185A (en) * 1990-03-21 1991-11-28 Merrell Dow Pharma Process for producing 8-sulfamil-methylen-2-amino-tetraline derivatives and pharmaceutical compositions containing them
US5194439A (en) * 1990-04-06 1993-03-16 John Wyeth & Brother Limited N-(2,3-dihydro-1,4-benzodioxinyl)-N-substituted aminopyrido-fused cycloalkanes
US5096908A (en) * 1990-05-04 1992-03-17 Eli Lilly And Company Method of inhibiting gastric acid secretion
US5340838A (en) * 1990-05-04 1994-08-23 Eli Lilly And Company Method of inhibiting gastric acid secretion with 2-phenylcyclopropylamines
US5258379A (en) * 1990-05-04 1993-11-02 Eli Lilly And Company Method of inhibiting gastric acid secretion with n-arylpiperazines
DE69124868T2 (de) * 1990-08-15 1997-07-10 Lilly Co Eli Ring-substituierte 2-Amino-1,2,3,4-tetra-hydronaphthaline, 3-Aminochromane und 3-Aminothiochromane
US5252586A (en) * 1990-09-28 1993-10-12 The Du Pont Merck Pharmaceutical Company Ether derivatives of alkyl piperidines and pyrrolidines as antipsychotic agents
DK0712837T3 (da) * 1991-02-08 2000-11-20 Lilly Co Eli Ringsubstituerede 2-amino-1,2,3,4-tetrahydronaphtalener og 3-aminochromaner
WO1992021654A2 (en) * 1991-05-20 1992-12-10 The Upjohn Company Carboxamido-(3,2n)-carbocyclic-2-aminotetralin derivatives
JP3155276B2 (ja) * 1991-05-20 2001-04-09 ファルマシア・アンド・アップジョン・カンパニー カルボキサミド−（１，２ｎ）−カルボサイクリック−２−アミノテトラリン誘導体
EP0591426A4 (en) * 1991-06-27 1996-08-21 Univ Virginia Commonwealth Sigma receptor ligands and the use thereof
US5288749A (en) * 1991-12-20 1994-02-22 Abbott Laboratories Tertiary and secondary amines as alpha-2 antagonists and serotonin uptake inhibitors
FR2686339B1 (fr) * 1992-01-22 1994-03-11 Adir Cie Nouveaux amides et sulfonamides naphtaleniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US5194658A (en) * 1992-03-02 1993-03-16 The Dow Chemical Company Process for making 2-amino-3-methyl-1-naphthalenecarbonitrile
EP0714292A4 (en) * 1993-06-23 1996-10-09 Cambridge Neuroscience Inc SIGMA RECEPTOR LIGANDS AND THEIR USE
GB9315566D0 (en) * 1993-07-28 1993-09-08 Smithkline Beecham Plc Medicaments
FR2711140B1 (fr) * 1993-10-12 1996-01-05 Sanofi Sa 1-Naphtylpyrazole-3-carboxamides substitués actifs sur la neurotensine, leur préparation, les compositions pharmaceutiques en contenant.
GB9420529D0 (en) * 1994-10-12 1994-11-30 Pfizer Ltd Indoles
US6025355A (en) 1997-05-19 2000-02-15 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
CZ370198A3 (cs) * 1996-05-31 1999-05-12 Pharmacia & Upjohn Company Aryl substituované cyklické aminy jako selektivní dopaminové D3 ligandy
US6242198B1 (en) 1996-07-25 2001-06-05 Cambridge Neuroscience, Inc. Methods of treatment of eye trauma and disorders
US6756389B2 (en) * 1996-08-09 2004-06-29 Cambridge Neuroscience, Inc. Pharmaceutically active compounds and methods of use
CA2288897A1 (en) * 1997-04-30 1998-11-05 Clint Duane Walker Aminotetralins as 5-ht1d.alpha. agonists
US6355674B1 (en) 1997-04-30 2002-03-12 Eli Lilly And Company Aminotetralins as 5-HT1D α Agonists
US20050032873A1 (en) * 2003-07-30 2005-02-10 Wyeth 3-Amino chroman and 2-amino tetralin derivatives
US20100006191A1 (en) * 2008-07-09 2010-01-14 Brush Wellman, Inc. HIGH STRENGTH Be/Cu ALLOYS WITH IMPROVED ELECTRICAL CONDUCTIVITY
DE102010020553A1 (de) 2010-05-14 2011-11-17 Bayer Schering Pharma Aktiengesellschaft Substituierte 8-Alkoxy-2-aminotetralin-Derivate und ihre Verwendung
CA2879456A1 (en) 2012-07-20 2014-01-23 Bayer Pharma Aktiengesellschaft Substituted aminoindane- and aminotetralincarboxylic acids and use thereof
CN104822661B (zh) 2012-07-20 2017-05-31 拜耳药业股份公司 5‑氨基四氢喹啉‑2‑羧酸及其用途
WO2019037791A1 (zh) * 2017-08-25 2019-02-28 广州市恒诺康医药科技有限公司 一种长效雷沙吉兰前药及其制备方法和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2407198A1 (fr) * 1977-10-27 1979-05-25 Torii & Co Ltd Esters amino- ou guanidino-1, 2, 3, 4-tetrahydro-1-naphtoiques
DE2803582A1 (de) * 1978-01-27 1979-08-02 Sandoz Ag Neue tetralinderivate, ihre herstellung und verwendung
SE8004002L (sv) * 1980-05-29 1981-11-30 Arvidsson Folke Lars Erik Terapeutiskt anvendbara tetralinderivat
DE3271003D1 (en) * 1981-09-15 1986-06-12 Ici Plc Amino-substituted tetralins and related homocyclic compounds
DE3371070D1 (en) * 1982-09-07 1987-05-27 Yoshitomi Pharmaceutical 4-amino-tetrahydro-2-naphthoic acid derivatives
US4510157A (en) * 1982-12-27 1985-04-09 Ayerst, Mckenna & Harrison, Inc. 6,7,8,9-Tetrahydro-1H-benz(g)indol-8-amine derivatives
DE3765206D1 (de) * 1986-07-28 1990-10-31 Whitby Research Inc Substituierte 2-aminotetraline.
DE3718317A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte basische 2-aminotetraline

Also Published As

Publication number Publication date
NO167282C (no) 1991-10-23
AU613884B2 (en) 1991-08-15
US4968679A (en) 1990-11-06
KR880007432A (ko) 1988-08-27
IL84875A0 (en) 1988-06-30
US5047422A (en) 1991-09-10
CN87101285A (zh) 1988-08-17
HUT46653A (en) 1988-11-28
AU8302987A (en) 1988-06-30
NO875005D0 (no) 1987-12-01
DK675787A (da) 1988-06-23
FI875598A0 (fi) 1987-12-18
EP0272534A2 (de) 1988-06-29
NO167282B (no) 1991-07-15
PT86425B (pt) 1990-11-20
NZ222977A (en) 1990-07-26
NO875005L (no) 1988-06-23
DE3719924A1 (de) 1988-06-30
EP0272534A3 (de) 1989-07-26
PT86425A (en) 1988-01-01
JPS63190857A (ja) 1988-08-08
DK675787D0 (da) 1987-12-21
JP2596956B2 (ja) 1997-04-02
US4873262A (en) 1989-10-10

Similar Documents

Publication Publication Date Title
ATE70057T1 (de) Antitumormittel.
DE3775679D1 (de) Vernebler.
DE3767169D1 (de) Sportschuh.
ATE57924T1 (de) 3-aryloxy-3-substituierte-propanamine.
NO875300D0 (no) Fortoeyningssystem.
FI875598A0 (fi) 8-substituerade 2-aminotetraliner.
DE3764043D1 (de) Alkylendiamine.
ATE63533T1 (de) Xylolisomerisierung.
DE3779761D1 (de) Abseilgeraet.
FI872480A0 (fi) Seriemagasin foer hagelpatroner.
DE3785294D1 (de) Neigungsmesser.
DE3786679D1 (de) Schmitt-triggerschaltung.
DE3773636D1 (de) Saeurebeschleunigte hydrocarboxilierung.
FI860054A0 (fi) Motionsanordning.
FI873991A0 (fi) Solstraolsfaongare.
DE3779382D1 (de) 3-6-diphenylpyridazine.
FI882921A0 (fi) Protaminzink-insulinpreparat.
DE3763648D1 (de) Rollski.
FI860046A0 (fi) Foerlaengningsanordning foer traefaner.
DE3766410D1 (de) Methylalkylcyclosiloxane.
DE3669032D1 (de) Okulopressionsgeraet.
FI874798A0 (fi) Dubbelspolningsmaskin.
DE3764485D1 (de) Polyglycidylamine.
DE3770459D1 (de) 3-halogensuccinimide.
FI860072A0 (fi) Mataranordning foer en spannmaolstork.

Legal Events

Date Code Title Description
FA Application withdrawn

Owner name: BAYER AKTIENGESELLSCHAFT