FI874055A - Protein med antikoagulanta och antimetastatiska egenskaper. - Google Patents

Protein med antikoagulanta och antimetastatiska egenskaper. Download PDF

Info

Publication number
FI874055A
FI874055A FI874055A FI874055A FI874055A FI 874055 A FI874055 A FI 874055A FI 874055 A FI874055 A FI 874055A FI 874055 A FI874055 A FI 874055A FI 874055 A FI874055 A FI 874055A
Authority
FI
Finland
Prior art keywords
antimetastatiska
antikoagulanta
egenskaper
och
med
Prior art date
Application number
FI874055A
Other languages
English (en)
Other versions
FI874055A0 (fi
Inventor
Gabriel J Gasic
Tatiana B Gasic
George P Tuszynski
Original Assignee
Pennsylvania Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pennsylvania Hospital filed Critical Pennsylvania Hospital
Publication of FI874055A0 publication Critical patent/FI874055A0/fi
Publication of FI874055A publication Critical patent/FI874055A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/14—Angiotensins: Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI874055A 1986-09-18 1987-09-17 Protein med antikoagulanta och antimetastatiska egenskaper. FI874055A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90858186A 1986-09-18 1986-09-18
US8843287A 1987-08-26 1987-08-26

Publications (2)

Publication Number Publication Date
FI874055A0 FI874055A0 (fi) 1987-09-17
FI874055A true FI874055A (fi) 1988-03-19

Family

ID=26778655

Family Applications (1)

Application Number Title Priority Date Filing Date
FI874055A FI874055A (fi) 1986-09-18 1987-09-17 Protein med antikoagulanta och antimetastatiska egenskaper.

Country Status (9)

Country Link
EP (1) EP0263608A3 (fi)
KR (1) KR880003975A (fi)
AU (1) AU615635B2 (fi)
DK (1) DK489187A (fi)
FI (1) FI874055A (fi)
IL (1) IL83912A (fi)
NO (1) NO170430C (fi)
NZ (1) NZ221835A (fi)
PT (1) PT85746B (fi)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3819078A1 (de) * 1988-06-04 1989-12-07 Hoechst Ag Amblyommin, ein neuer wirkstoff fuer die antikoagulationstherapie
DE58907266T2 (de) * 1988-06-11 1994-09-29 Ciba Geigy Ag Polypeptide mit einer die Koagulierung hemmenden Wirkung.
US5268296A (en) * 1988-06-11 1993-12-07 Ciba-Geigy Corporation DNA vector and recombinant host cell for production of hirullin P6 and P18
US4832849A (en) * 1988-06-16 1989-05-23 Merrell Dow Pharmaceuticals Inc. Extraction and purification of an anticoagulant principle from the south american leech, haementeria ghilianii
KR0185973B1 (ko) * 1989-06-20 1999-05-01 게리 디. 스트리트 남미의 거머리인 헤멘테리아 길리아니로부터의 항전이 물질 길란텐
US5648461A (en) * 1990-02-22 1997-07-15 W.R. Grace & Co.-Conn Synthetic analogs of thrombospondin and therapeutic use thereof
US5190918A (en) * 1990-02-22 1993-03-02 W. R. Grace & Co.-Conn. Peptide fragments and analogs of thrombospondin and methods of use
US5200397A (en) * 1990-02-22 1993-04-06 W. R. Grace & Co.-Conn. Use of peptide analogs of thrombospondin for the inhibition of angiogenic activity
US6239110B1 (en) 1990-02-22 2001-05-29 W.R. Grace & Co. -Conn. Synthetic analogs of thrombospondin and therapeutic use thereof
CA2047527A1 (en) * 1990-07-24 1992-01-25 Christopher Dunwiddie Method for administering a therapeutic anticoagulant
CA2052486A1 (en) * 1990-10-09 1992-04-10 Thomas M. Connolly Protein for inhibiting collagen-stimulated platelet aggregation
US5801017A (en) * 1993-04-09 1998-09-01 Bio-Technology General Corp. Production of recombinant factor Xa inhibitor of leech Hirudo medicinalis
US5824641A (en) 1993-04-09 1998-10-20 Bio-Technology General Corp Method of treating of preventing influenza
US6339062B1 (en) 1998-11-23 2002-01-15 Inkine Pharmaceutical Company, Inc. Retroinverso polypeptides that mimic or inhibit thrombospondin activity
GB9930659D0 (en) * 1999-12-24 2000-02-16 Bio Discovery Ltd Inhibitors of complement activation
US7691839B2 (en) 2005-09-28 2010-04-06 Biovascular, Inc. Methods and compositions for blocking platelet and cell adhesion, cell migration and inflammation
CN109620847B (zh) * 2018-12-11 2022-07-26 山东沃华医药科技股份有限公司 一种脑血疏口服液中的水蛭抗凝成分的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4588587A (en) * 1983-03-01 1986-05-13 Pennsylvania Hospital Method of treatment to inhibit metastasis

Also Published As

Publication number Publication date
AU615635B2 (en) 1991-10-10
IL83912A (en) 1993-05-13
EP0263608A3 (en) 1989-06-14
NO873859D0 (no) 1987-09-15
NO873859L (no) 1988-03-21
DK489187A (da) 1988-03-19
FI874055A0 (fi) 1987-09-17
PT85746B (pt) 1990-07-31
AU7862687A (en) 1988-03-24
PT85746A (en) 1987-10-01
KR880003975A (ko) 1988-05-31
DK489187D0 (da) 1987-09-17
NO170430B (no) 1992-07-06
NO170430C (no) 1992-10-14
IL83912A0 (en) 1988-02-29
EP0263608A2 (en) 1988-04-13
NZ221835A (en) 1992-03-26

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Legal Events

Date Code Title Description
FD Application lapsed
MM Patent lapsed

Owner name: PENNSYLVANIA HOSPITAL