FI871322A - Nya benzotiazinderivat. - Google Patents

Nya benzotiazinderivat. Download PDF

Info

Publication number
FI871322A
FI871322A FI871322A FI871322A FI871322A FI 871322 A FI871322 A FI 871322A FI 871322 A FI871322 A FI 871322A FI 871322 A FI871322 A FI 871322A FI 871322 A FI871322 A FI 871322A
Authority
FI
Finland
Prior art keywords
hydrogen
derivatives
alkyl
lower alkyl
nitro
Prior art date
Application number
FI871322A
Other languages
English (en)
Other versions
FI87352C (fi
FI871322A0 (fi
FI87352B (fi
Inventor
Jun-Ichi Iwao
Tadashi Iso
Masayuki Oya
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP1985/000426 external-priority patent/WO1987000837A1/ja
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Publication of FI871322A0 publication Critical patent/FI871322A0/fi
Publication of FI871322A publication Critical patent/FI871322A/fi
Application granted granted Critical
Publication of FI87352B publication Critical patent/FI87352B/fi
Publication of FI87352C publication Critical patent/FI87352C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Sheets, Magazines, And Separation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI871322A 1985-07-29 1987-03-26 Foerfarande foer framstaellning av farmaceutisk vaerdefull 2-(substituerad fenyl)-3-oxo-2h-1,4-benzotiazin FI87352C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP8500426 1985-07-29
PCT/JP1985/000426 WO1987000837A1 (en) 1985-07-29 1985-07-29 Novel benzothiazine derivatives
JP17353185 1985-08-06
JP17353185 1985-08-06
JP8600379 1986-07-21
PCT/JP1986/000379 WO1987000838A1 (en) 1985-07-29 1986-07-21 Novel benzothiazine derivatives

Publications (4)

Publication Number Publication Date
FI871322A0 FI871322A0 (fi) 1987-03-26
FI871322A true FI871322A (fi) 1987-03-26
FI87352B FI87352B (fi) 1992-09-15
FI87352C FI87352C (fi) 1992-12-28

Family

ID=15962257

Family Applications (1)

Application Number Title Priority Date Filing Date
FI871322A FI87352C (fi) 1985-07-29 1987-03-26 Foerfarande foer framstaellning av farmaceutisk vaerdefull 2-(substituerad fenyl)-3-oxo-2h-1,4-benzotiazin

Country Status (10)

Country Link
US (1) US4786635A (fi)
EP (1) EP0237573B1 (fi)
KR (1) KR890004196B1 (fi)
AT (1) ATE71622T1 (fi)
AU (1) AU587057B2 (fi)
DE (1) DE3683483D1 (fi)
DK (1) DK158087A (fi)
FI (1) FI87352C (fi)
NO (1) NO170082C (fi)
WO (1) WO1987000838A1 (fi)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3614363A1 (de) * 1986-04-28 1987-10-29 Hoechst Ag Benzothiazinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
AT389113B (de) * 1987-10-08 1989-10-25 Hoechst Ag Neue benzothiazinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
AT389112B (de) * 1987-10-08 1989-10-25 Hoechst Ag Benzothiazinon-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
DK0429676T3 (fi) * 1989-06-16 1997-03-10 Santen Pharmaceutical Co Ltd
TW207952B (fi) * 1990-11-29 1993-06-21 Santen Pharmaceutical Co Ltd
IL137656A0 (en) * 1998-03-31 2001-10-31 Warner Lambert Co Benzoxazinones/benzothiazinones as serine protease inhibitors
AP2005003232A0 (en) 2002-08-19 2005-03-31 Pfizer Prod Inc Combination therapy for hyperproliferative diseases.
AU2005269465A1 (en) * 2004-07-26 2006-02-09 Cotherix, Inc. Treatment of pulmonary hypertension by inhaled iloprost with a microparticle formulation
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
EP2351569B1 (en) 2005-10-26 2012-08-22 Asahi Kasei Pharma Corporation Fasudil in combination therapies for the treatment of pulmonary arterial hypertension
ATE551059T1 (de) * 2005-10-26 2012-04-15 Asahi Kasei Pharma Corp Fasudil in kombination mit bosentan zur behandlung von pulmonaler arterieller hypertonie
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
ES2382009T3 (es) 2006-12-01 2012-06-04 Bristol-Myers Squibb Company Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares
US20090069413A1 (en) * 2007-09-09 2009-03-12 Protia, Llc Deuterium-enriched olopatadine
WO2012037665A1 (en) 2010-09-24 2012-03-29 Oral Delivery Technology Ltd. Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions
CN105143203A (zh) 2013-04-17 2015-12-09 辉瑞大药厂 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
WO2020150473A2 (en) 2019-01-18 2020-07-23 Dogma Therapeutics, Inc. Pcsk9 inhibitors and methods of use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5651465A (en) * 1979-10-02 1981-05-09 Yoshitomi Pharmaceut Ind Ltd Benzothiazine derivative
US4584300A (en) * 1983-02-07 1986-04-22 Santen Pharmaceutical Co., Ltd. Platelet anti-aggregative- and calcium antagonistic -1,4-benzothiazin-3-one derivatives, compositions, and methods of use therefor
JPS59144775A (ja) * 1983-02-07 1984-08-18 Santen Pharmaceut Co Ltd ヒドロキシフエニルベンゾチアジン誘導体およびその製造法
JPS59148771A (ja) * 1983-02-09 1984-08-25 Santen Pharmaceut Co Ltd ベンゾチアジン誘導体
DE3347173A1 (de) * 1983-12-27 1985-07-04 Hoechst Ag, 6230 Frankfurt Neue benzothiazin-derivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
JPS60166674A (ja) * 1984-02-09 1985-08-29 Santen Pharmaceut Co Ltd ベンゾチアジン誘導体
EP0233291B1 (en) * 1985-03-19 1991-03-13 Santen Pharmaceutical Co., Ltd. 2-arylbenzothiazine derivatives
AU4673285A (en) * 1985-07-29 1987-03-05 Santen Pharmaceutical Co. Ltd. Novel benzothiazine derivatives

Also Published As

Publication number Publication date
NO170082C (no) 1992-09-09
DE3683483D1 (de) 1992-02-27
FI87352C (fi) 1992-12-28
NO170082B (no) 1992-06-01
FI871322A0 (fi) 1987-03-26
EP0237573A4 (en) 1987-10-26
US4786635A (en) 1988-11-22
DK158087D0 (da) 1987-03-27
AU6137186A (en) 1987-03-05
FI87352B (fi) 1992-09-15
KR890004196B1 (ko) 1989-10-27
KR870700613A (ko) 1987-12-30
EP0237573B1 (en) 1992-01-15
DK158087A (da) 1987-03-27
NO871314D0 (no) 1987-03-27
WO1987000838A1 (en) 1987-02-12
AU587057B2 (en) 1989-08-03
EP0237573A1 (en) 1987-09-23
ATE71622T1 (de) 1992-02-15

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Legal Events

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MM Patent lapsed

Owner name: SANTEN PHARMACEUTICAL CO., LTD