FI870315A - Mellanprodukter vid -laktam-föreningars och 1 -metylkarbapenem-föreningars syntes, och förfarande för deras framställning - Google Patents

Mellanprodukter vid -laktam-föreningars och 1 -metylkarbapenem-föreningars syntes, och förfarande för deras framställning Download PDF

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Publication number
FI870315A
FI870315A FI870315A FI870315A FI870315A FI 870315 A FI870315 A FI 870315A FI 870315 A FI870315 A FI 870315A FI 870315 A FI870315 A FI 870315A FI 870315 A FI870315 A FI 870315A
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FI
Finland
Prior art keywords
compounds
intermediates
synthesis
preparation
methylcarbapenem
Prior art date
Application number
FI870315A
Other languages
English (en)
Finnish (fi)
Other versions
FI92059C (sv
FI92059B (sv
FI870315A0 (sv
Inventor
Shiro Terashima
Yoshio Ito
Takeo Kawabata
Kunikazu Sakai
Tamejiro Hiyama
Yoshikazu Kimura
Makoto Sunagawa
Katsumi Tamoto
Akira Sasaki
Original Assignee
Sumitomo Pharma
Sagami Chem Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharma, Sagami Chem Res filed Critical Sumitomo Pharma
Publication of FI870315A0 publication Critical patent/FI870315A0/sv
Publication of FI870315A publication Critical patent/FI870315A/sv
Application granted granted Critical
Publication of FI92059B publication Critical patent/FI92059B/sv
Publication of FI92059C publication Critical patent/FI92059C/sv

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30Oxygen or sulfur atoms
    • C07D233/32One oxygen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30Oxygen or sulfur atoms
    • C07D233/32One oxygen atom
    • C07D233/38One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18Oxygen atoms
    • C07D263/20Oxygen atoms attached in position 2
    • C07D263/26Oxygen atoms attached in position 2 with hetero atoms or acyl radicals directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI870315A 1986-01-27 1987-01-26 Mellanprodukter vid -laktam-föreningars och 1 -metylkarbapenem-föreningars syntes, och förfarande för deras framställning FI92059C (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP1374786 1986-01-27
JP1374786 1986-01-27
JP4606086 1986-03-05
JP4606086 1986-03-05

Publications (4)

Publication Number Publication Date
FI870315A0 FI870315A0 (sv) 1987-01-26
FI870315A true FI870315A (sv) 1987-07-28
FI92059B FI92059B (sv) 1994-06-15
FI92059C FI92059C (sv) 1994-09-26

Family

ID=26349587

Family Applications (1)

Application Number Title Priority Date Filing Date
FI870315A FI92059C (sv) 1986-01-27 1987-01-26 Mellanprodukter vid -laktam-föreningars och 1 -metylkarbapenem-föreningars syntes, och förfarande för deras framställning

Country Status (9)

Country Link
EP (1) EP0232786B1 (sv)
JP (1) JP2789190B2 (sv)
KR (1) KR940008748B1 (sv)
DE (1) DE3778049D1 (sv)
ES (1) ES2039210T3 (sv)
FI (1) FI92059C (sv)
GR (1) GR3004335T3 (sv)
HU (2) HU209952B (sv)
IE (1) IE59138B1 (sv)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6011150A (en) * 1992-11-13 2000-01-04 Tanabe Seiyaku Co., Ltd. Azetidinone compound and process for preparation thereof
US5631363A (en) * 1992-11-13 1997-05-20 Tanabe Seiyaku Co., Ltd. Azetidinone compound and process for preparation thereof
US5442055A (en) * 1992-11-13 1995-08-15 Tanabe Seiyaku Co., Ltd. Azetidinone compound and process for preparation thereof
JP2856913B2 (ja) * 1993-05-18 1999-02-10 宣治 山下 可撓性型枠材及びそれを利用した貫通孔形成工法
US5550229A (en) * 1993-06-23 1996-08-27 Tanabe Seiyaku Co., Ltd. Alkylation process for preparing azetidinone compound and starting compound therefor
IT1391259B1 (it) * 2008-10-28 2011-12-01 Acs Dobfar Spa Derivati 1,3-imidazolidinici e loro utilizzo per la produzione di carbapenem
EP2345645A1 (en) 2009-12-22 2011-07-20 Savior Lifetec Corporation Method for manufacturing stereoselective preparation of 4-bma using a chiral auxiliary and chiral auxiliary
CN102250033A (zh) * 2011-05-27 2011-11-23 菏泽睿智科技开发有限公司 一种合成培南类抗生素的新型手性辅基的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH422743A (de) * 1961-11-10 1966-10-31 Sandoz Ag Verfahren zur Herstellung neuer Phosphorsäureester
GB1482879A (en) * 1975-07-24 1977-08-17 Nippon Chemiphar Co 5-benzyl-2-oxazolidone derivatives and a process for producing the same
JPS6169839A (ja) * 1984-08-24 1986-04-10 Toray Ind Inc 着色エポキシ系球状微粒子
JPS61275267A (ja) * 1985-03-29 1986-12-05 メルク エンド カムパニ− インコ−ポレ−テツド 1−β−メチルカルバペネム抗生物質中間体の鏡像異性選択的製造方法
CA1276156C (en) * 1985-03-29 1990-11-13 Thomas N. Salzmann Enantioselective process for producing 1-beta- methylcarbapenem antibiotic intermediates

Also Published As

Publication number Publication date
HUT45233A (en) 1988-06-28
EP0232786B1 (en) 1992-04-08
ES2039210T3 (es) 1993-09-16
FI92059C (sv) 1994-09-26
HU895128D0 (en) 1990-03-28
JPS6310765A (ja) 1988-01-18
GR3004335T3 (sv) 1993-03-31
IE870199L (en) 1987-07-27
IE59138B1 (en) 1994-01-12
HU199428B (en) 1990-02-28
EP0232786A1 (en) 1987-08-19
HU209952B (en) 1994-12-28
JP2789190B2 (ja) 1998-08-20
DE3778049D1 (de) 1992-05-14
FI92059B (sv) 1994-06-15
FI870315A0 (sv) 1987-01-26
KR940008748B1 (ko) 1994-09-26
KR870007142A (ko) 1987-08-17

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Date Code Title Description
BB Publication of examined application
FG Patent granted

Owner name: SUMITOMO PHARMACEUTICALS COMPANY

PC Transfer of assignment of patent

Owner name: DAINIPPON SUMITOMO PHARMA CO., LTD.

Free format text: DAINIPPON SUMITOMO PHARMA CO., LTD.

MA Patent expired