FI864737A - Nya basiskt substituerade pyridinfoereningar, foerfaranden foer deras framstaellning, dessa innehaollande laekemedel och deras anvaendning. - Google Patents

Nya basiskt substituerade pyridinfoereningar, foerfaranden foer deras framstaellning, dessa innehaollande laekemedel och deras anvaendning. Download PDF

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Publication number
FI864737A
FI864737A FI864737A FI864737A FI864737A FI 864737 A FI864737 A FI 864737A FI 864737 A FI864737 A FI 864737A FI 864737 A FI864737 A FI 864737A FI 864737 A FI864737 A FI 864737A
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FI
Finland
Prior art keywords
carbon atoms
hydrogen
group
phenyl
alkoxy
Prior art date
Application number
FI864737A
Other languages
English (en)
Finnish (fi)
Other versions
FI864737A0 (fi
Inventor
Ulrich Elben
Hiristo Anagnostopulos
Robert R Bartlett
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI864737A0 publication Critical patent/FI864737A0/fi
Publication of FI864737A publication Critical patent/FI864737A/fi

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84Nitriles
    • C07D213/85Nitriles in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Inorganic Insulating Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI864737A 1985-11-23 1986-11-20 Nya basiskt substituerade pyridinfoereningar, foerfaranden foer deras framstaellning, dessa innehaollande laekemedel och deras anvaendning. FI864737A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853541428 DE3541428A1 (de) 1985-11-23 1985-11-23 Neue basisch substituierte pyridinverbindungen, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung

Publications (2)

Publication Number Publication Date
FI864737A0 FI864737A0 (fi) 1986-11-20
FI864737A true FI864737A (fi) 1987-05-24

Family

ID=6286631

Family Applications (1)

Application Number Title Priority Date Filing Date
FI864737A FI864737A (fi) 1985-11-23 1986-11-20 Nya basiskt substituerade pyridinfoereningar, foerfaranden foer deras framstaellning, dessa innehaollande laekemedel och deras anvaendning.

Country Status (19)

Country Link
US (1) US4792554A (xx)
EP (1) EP0224159B1 (xx)
JP (1) JPS62129271A (xx)
CN (1) CN86107899A (xx)
AT (1) ATE59637T1 (xx)
AU (1) AU587086B2 (xx)
CA (1) CA1256873A (xx)
DE (2) DE3541428A1 (xx)
DK (1) DK558786A (xx)
ES (1) ES2032377T3 (xx)
FI (1) FI864737A (xx)
GR (1) GR3001470T3 (xx)
HU (1) HU196998B (xx)
IL (1) IL80715A (xx)
NO (1) NO166321C (xx)
NZ (1) NZ218359A (xx)
PH (1) PH24129A (xx)
PT (1) PT83786B (xx)
ZA (1) ZA868834B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK623586A (da) * 1985-12-27 1987-06-28 Eisai Co Ltd Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne
US4916142A (en) * 1987-02-02 1990-04-10 Boc, Inc. N-heterocyclic-N-(4-piperidinyl)amides and pharmaceutical compositions and their use as analgesics
US6129930A (en) 1993-09-20 2000-10-10 Bova; David J. Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
US6818229B1 (en) 1993-09-20 2004-11-16 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia
US6080428A (en) 1993-09-20 2000-06-27 Bova; David J. Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
US6746691B2 (en) 1993-09-20 2004-06-08 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics
US6676967B1 (en) 1993-09-20 2004-01-13 Kos Pharmaceuticals, Inc. Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE786565A (fr) * 1971-07-23 1973-01-22 Upjohn Co Nouveaux oxydes de pyridine substitues et leur preparation
DE2334401A1 (de) * 1973-07-06 1975-01-23 Hoechst Ag 2-nitro-3-aminoalkylamino-pyridine und verfahren zu ihrer herstellung
DE2900504A1 (de) * 1979-01-08 1980-07-24 Hoechst Ag Neue substituierte 4-aminopyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
GB8320699D0 (en) * 1983-08-01 1983-09-01 Wellcome Found Ethylenediamines

Also Published As

Publication number Publication date
NO864665L (no) 1987-05-25
PH24129A (en) 1990-03-05
NZ218359A (en) 1989-05-29
NO864665D0 (no) 1986-11-21
NO166321C (no) 1991-07-03
DK558786D0 (da) 1986-11-21
FI864737A0 (fi) 1986-11-20
PT83786A (de) 1986-12-01
ES2032377T3 (es) 1993-02-16
AU6557086A (en) 1987-05-28
HU196998B (en) 1989-02-28
EP0224159B1 (de) 1991-01-02
NO166321B (no) 1991-03-25
US4792554A (en) 1988-12-20
GR3001470T3 (en) 1992-10-08
AU587086B2 (en) 1989-08-03
JPS62129271A (ja) 1987-06-11
EP0224159A1 (de) 1987-06-03
DK558786A (da) 1987-05-24
PT83786B (pt) 1989-06-30
CN86107899A (zh) 1987-07-29
DE3676459D1 (de) 1991-02-07
IL80715A (en) 1990-08-31
DE3541428A1 (de) 1987-05-27
IL80715A0 (en) 1987-02-27
CA1256873A (en) 1989-07-04
ZA868834B (en) 1987-07-29
HUT42473A (en) 1987-07-28
ATE59637T1 (de) 1991-01-15

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Owner name: HOECHST AKTIENGESELLSCHAFT