GR3001470T3 - Pyridine compounds, substituted by basic groups, process for their preparation, medicaments containing them and their use - Google Patents

Pyridine compounds, substituted by basic groups, process for their preparation, medicaments containing them and their use

Info

Publication number
GR3001470T3
GR3001470T3 GR91400031T GR910400031T GR3001470T3 GR 3001470 T3 GR3001470 T3 GR 3001470T3 GR 91400031 T GR91400031 T GR 91400031T GR 910400031 T GR910400031 T GR 910400031T GR 3001470 T3 GR3001470 T3 GR 3001470T3
Authority
GR
Greece
Prior art keywords
carbon atoms
hydrogen
substituted
group
preparation
Prior art date
Application number
GR91400031T
Other languages
English (en)
Inventor
Ulrich Dr Elben
Hiristo Anagnostopulos
Robert R Dr Bartlett
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of GR3001470T3 publication Critical patent/GR3001470T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
GR91400031T 1985-11-23 1991-02-12 Pyridine compounds, substituted by basic groups, process for their preparation, medicaments containing them and their use GR3001470T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853541428 DE3541428A1 (de) 1985-11-23 1985-11-23 Neue basisch substituierte pyridinverbindungen, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung

Publications (1)

Publication Number Publication Date
GR3001470T3 true GR3001470T3 (en) 1992-10-08

Family

ID=6286631

Family Applications (1)

Application Number Title Priority Date Filing Date
GR91400031T GR3001470T3 (en) 1985-11-23 1991-02-12 Pyridine compounds, substituted by basic groups, process for their preparation, medicaments containing them and their use

Country Status (19)

Country Link
US (1) US4792554A (el)
EP (1) EP0224159B1 (el)
JP (1) JPS62129271A (el)
CN (1) CN86107899A (el)
AT (1) ATE59637T1 (el)
AU (1) AU587086B2 (el)
CA (1) CA1256873A (el)
DE (2) DE3541428A1 (el)
DK (1) DK558786A (el)
ES (1) ES2032377T3 (el)
FI (1) FI864737A (el)
GR (1) GR3001470T3 (el)
HU (1) HU196998B (el)
IL (1) IL80715A (el)
NO (1) NO166321C (el)
NZ (1) NZ218359A (el)
PH (1) PH24129A (el)
PT (1) PT83786B (el)
ZA (1) ZA868834B (el)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK623586A (da) * 1985-12-27 1987-06-28 Eisai Co Ltd Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne
US4916142A (en) * 1987-02-02 1990-04-10 Boc, Inc. N-heterocyclic-N-(4-piperidinyl)amides and pharmaceutical compositions and their use as analgesics
US6080428A (en) 1993-09-20 2000-06-27 Bova; David J. Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
US6818229B1 (en) 1993-09-20 2004-11-16 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia
US6129930A (en) 1993-09-20 2000-10-10 Bova; David J. Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
US6676967B1 (en) 1993-09-20 2004-01-13 Kos Pharmaceuticals, Inc. Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia
US6746691B2 (en) 1993-09-20 2004-06-08 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE786565A (fr) * 1971-07-23 1973-01-22 Upjohn Co Nouveaux oxydes de pyridine substitues et leur preparation
DE2334401A1 (de) * 1973-07-06 1975-01-23 Hoechst Ag 2-nitro-3-aminoalkylamino-pyridine und verfahren zu ihrer herstellung
DE2900504A1 (de) * 1979-01-08 1980-07-24 Hoechst Ag Neue substituierte 4-aminopyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
GB8320699D0 (en) * 1983-08-01 1983-09-01 Wellcome Found Ethylenediamines

Also Published As

Publication number Publication date
NO864665L (no) 1987-05-25
PH24129A (en) 1990-03-05
AU6557086A (en) 1987-05-28
NO864665D0 (no) 1986-11-21
JPS62129271A (ja) 1987-06-11
ATE59637T1 (de) 1991-01-15
FI864737A0 (fi) 1986-11-20
NZ218359A (en) 1989-05-29
CA1256873A (en) 1989-07-04
EP0224159B1 (de) 1991-01-02
NO166321B (no) 1991-03-25
NO166321C (no) 1991-07-03
DE3541428A1 (de) 1987-05-27
FI864737A (fi) 1987-05-24
ZA868834B (en) 1987-07-29
DK558786A (da) 1987-05-24
IL80715A (en) 1990-08-31
PT83786B (pt) 1989-06-30
ES2032377T3 (es) 1993-02-16
HU196998B (en) 1989-02-28
DK558786D0 (da) 1986-11-21
DE3676459D1 (de) 1991-02-07
CN86107899A (zh) 1987-07-29
EP0224159A1 (de) 1987-06-03
IL80715A0 (en) 1987-02-27
HUT42473A (en) 1987-07-28
PT83786A (de) 1986-12-01
AU587086B2 (en) 1989-08-03
US4792554A (en) 1988-12-20

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