FI862560A - Glycerolderivat. - Google Patents

Glycerolderivat. Download PDF

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Publication number
FI862560A
FI862560A FI862560A FI862560A FI862560A FI 862560 A FI862560 A FI 862560A FI 862560 A FI862560 A FI 862560A FI 862560 A FI862560 A FI 862560A FI 862560 A FI862560 A FI 862560A
Authority
FI
Finland
Prior art keywords
glycerolderivat
Prior art date
Application number
FI862560A
Other languages
English (en)
Other versions
FI862560A0 (fi
Inventor
Richard Barner
Kaspar Burri
Jean-Marie Cassal
Paul Hadvary
Georges Hirth
Klaus Mueller
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI862560A0 publication Critical patent/FI862560A0/fi
Publication of FI862560A publication Critical patent/FI862560A/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
FI862560A 1985-06-18 1986-06-16 Glycerolderivat. FI862560A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH256785 1985-06-18

Publications (2)

Publication Number Publication Date
FI862560A0 FI862560A0 (fi) 1986-06-16
FI862560A true FI862560A (fi) 1986-12-19

Family

ID=4236705

Family Applications (1)

Application Number Title Priority Date Filing Date
FI862560A FI862560A (fi) 1985-06-18 1986-06-16 Glycerolderivat.

Country Status (16)

Country Link
US (2) US4863941A (fi)
EP (1) EP0208932A3 (fi)
JP (1) JPS61293954A (fi)
KR (1) KR870000282A (fi)
AR (1) AR242175A1 (fi)
AU (1) AU596593B2 (fi)
DK (1) DK281886A (fi)
ES (1) ES8706595A1 (fi)
FI (1) FI862560A (fi)
HU (1) HU196350B (fi)
IL (1) IL79120A0 (fi)
MC (1) MC1757A1 (fi)
NO (1) NO862403L (fi)
NZ (1) NZ216546A (fi)
PT (1) PT82772B (fi)
ZA (1) ZA864486B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989007100A1 (en) * 1988-02-05 1989-08-10 Schering Corporation 2,2-disubstituted glycerol and glycerol-like compounds, compositions and methods of use
WO1989007099A1 (en) * 1988-02-05 1989-08-10 Schering Corporation 2,2-disubstituted glycerol and glycerol-like compounds, compositions and methods of use
US5185334A (en) * 1989-07-31 1993-02-09 Schering Corporation 2,2-disubstituted glycerol and glycerol-like compounds, compositions and methods of use
US5273985A (en) * 1988-07-04 1993-12-28 Eisai Co., Ltd. Glycerin derivative and its pharmacological use
FI97883C (fi) * 1988-07-04 1997-03-10 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen glyserolijohdannaisen valmistamiseksi
GR1000688B (el) * 1989-12-22 1992-10-08 Sod Conseils Rech Applic Μεθοδος παρασκευης παραγωγων γλυκερινης.
JP2604268B2 (ja) * 1990-04-09 1997-04-30 富士写真フイルム株式会社 ペプチド誘導体両親媒性化合物、その中間体、ペプチド誘導体両親媒性化合物を用いたリポソームおよび薄膜
US5512591A (en) * 1993-02-18 1996-04-30 President And Fellows Of Harvard College Treatments for diseases characterized by neovascularization
US5633274A (en) * 1993-02-18 1997-05-27 President And Fellows Of Harvard College Cancer treatments
US5556871A (en) * 1995-04-24 1996-09-17 President & Fellows Of Harvard College Method for treating epithelial precancerous lesions with topical inidazoles

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE790089A (fr) * 1971-10-14 1973-04-13 Ici Ltd Derives de l'imidazole
US4493832A (en) * 1981-07-03 1985-01-15 Fujisawa Pharmaceutical Co., Ltd. Certain glycerol-phosphoryl choline derivatives, compositions containing same and method of using same
JPH0240648B2 (ja) * 1981-08-25 1990-09-12 Takeda Chemical Industries Ltd Ketsushobankatsuseiinshokuseizai
JPS5835194A (ja) * 1981-08-25 1983-03-01 Takeda Chem Ind Ltd カルバミン酸エステル類
JPS58154512A (ja) * 1982-03-09 1983-09-14 Takeda Chem Ind Ltd 血小板活性化因子抑制剤
DE3212387A1 (de) * 1982-04-02 1983-10-13 Bayer Ag, 5090 Leverkusen Glycerinphosphatide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
JPS58192825A (ja) * 1982-05-06 1983-11-10 Takeda Chem Ind Ltd グリセロール誘導体
EP0094586A3 (en) * 1982-05-13 1984-06-06 Ono Pharmaceutical Co., Ltd. Glycerol derivatives, process for preparing same and pharmaceutical composition containing same
JPS5931738A (ja) * 1982-08-17 1984-02-20 Ono Pharmaceut Co Ltd グリセリン誘導体、その製造方法及びその誘導体を含有する薬剤
JPS5988447A (ja) * 1982-11-11 1984-05-22 Ono Pharmaceut Co Ltd グリセリン誘導体、その製造方法及びその誘導体を含有する薬剤
JPS604196A (ja) * 1983-06-22 1985-01-10 Nippon Soda Co Ltd グリセリン誘導体
JPS6081193A (ja) * 1983-10-11 1985-05-09 Takeda Chem Ind Ltd リン脂質
JPS6081194A (ja) * 1983-10-11 1985-05-09 Takeda Chem Ind Ltd ケトアルキルリン脂質
JPS60100544A (ja) * 1983-11-08 1985-06-04 Ono Pharmaceut Co Ltd 新規なグリセリン誘導体,その製造方法及びその誘導体を含有する薬剤
JPS60104066A (ja) * 1983-11-10 1985-06-08 Ono Pharmaceut Co Ltd グリセリン誘導体
DK160818C (da) * 1983-12-30 1991-10-07 Hoffmann La Roche N-ring-holdige glycerolderivater, fremgangsmaade til fremstilling deraf, anvendelse deraf til fremstilling af et blodpladeaktiveringsfaktorhaemmende middel samt laegemidler indeholdende en saadan forbindelse
DE3586746D1 (de) * 1984-04-03 1992-11-19 Takeda Chemical Industries Ltd Lipidderivate, ihre produktion und verwendung.
JPH06419A (ja) * 1992-06-22 1994-01-11 Amada Co Ltd 工業用ロボットの制御装置
JPH08335194A (ja) * 1995-06-07 1996-12-17 Canon Inc 情報処理装置及び情報処理方法

Also Published As

Publication number Publication date
EP0208932A2 (de) 1987-01-21
MC1757A1 (fr) 1987-04-24
ES556110A0 (es) 1987-07-16
AU5890186A (en) 1986-12-24
IL79120A0 (en) 1986-09-30
PT82772A (en) 1986-07-01
JPS61293954A (ja) 1986-12-24
DK281886D0 (da) 1986-06-16
DK281886A (da) 1986-12-19
US4863941A (en) 1989-09-05
AR242175A1 (es) 1993-03-31
ZA864486B (en) 1987-02-25
NO862403D0 (no) 1986-06-17
NZ216546A (en) 1990-03-27
AU596593B2 (en) 1990-05-10
FI862560A0 (fi) 1986-06-16
US5057530A (en) 1991-10-15
NO862403L (no) 1986-12-19
ES8706595A1 (es) 1987-07-16
PT82772B (pt) 1989-01-17
EP0208932A3 (de) 1989-11-29
HUT43803A (en) 1987-12-28
HU196350B (en) 1988-11-28
KR870000282A (ko) 1987-02-17

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Owner name: F. HOFFMANN-LA ROCHE AG