FI853843L - Foerfarande foer framstaellning av direkt komprimerbar kornformig mannitol. - Google Patents

Foerfarande foer framstaellning av direkt komprimerbar kornformig mannitol.

Info

Publication number
FI853843L
FI853843L FI853843A FI853843A FI853843L FI 853843 L FI853843 L FI 853843L FI 853843 A FI853843 A FI 853843A FI 853843 A FI853843 A FI 853843A FI 853843 L FI853843 L FI 853843L
Authority
FI
Finland
Prior art keywords
mannitol
kornformig
komprimerbar
direkt
raw material
Prior art date
Application number
FI853843A
Other languages
English (en)
Other versions
FI85367C (fi
FI85367B (fi
FI853843A0 (fi
Inventor
Michel Serpelloni
Patrick Lemay
Original Assignee
Roquette Freres
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roquette Freres filed Critical Roquette Freres
Publication of FI853843A0 publication Critical patent/FI853843A0/fi
Publication of FI853843L publication Critical patent/FI853843L/fi
Application granted granted Critical
Publication of FI85367B publication Critical patent/FI85367B/fi
Publication of FI85367C publication Critical patent/FI85367C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/18—Polyhydroxylic acyclic alcohols
    • C07C31/26—Hexahydroxylic alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/20—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by expressing the material, e.g. through sieves and fragmenting the extruded length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/74—Separation; Purification; Use of additives, e.g. for stabilisation
    • C07C29/76—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI853843A 1984-10-03 1985-10-03 Foerfarande foer framstaellning av direkt komprimerbar kornformig mannitol. FI85367C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8415212 1984-10-03
FR8415212A FR2571046B1 (fr) 1984-10-03 1984-10-03 Procede de preparation de mannitol granulaire directement compressible

Publications (4)

Publication Number Publication Date
FI853843A0 FI853843A0 (fi) 1985-10-03
FI853843L true FI853843L (fi) 1986-04-04
FI85367B FI85367B (fi) 1991-12-31
FI85367C FI85367C (fi) 1992-04-10

Family

ID=9308323

Family Applications (1)

Application Number Title Priority Date Filing Date
FI853843A FI85367C (fi) 1984-10-03 1985-10-03 Foerfarande foer framstaellning av direkt komprimerbar kornformig mannitol.

Country Status (16)

Country Link
US (1) US5160680A (fi)
EP (1) EP0177428B1 (fi)
JP (1) JPH0643352B2 (fi)
KR (1) KR930007408B1 (fi)
CN (1) CN1005963B (fi)
AT (1) ATE36466T1 (fi)
CA (1) CA1272216A (fi)
DE (1) DE3564380D1 (fi)
DK (1) DK173282B1 (fi)
ES (1) ES8700219A1 (fi)
FI (1) FI85367C (fi)
FR (1) FR2571046B1 (fi)
GR (1) GR852391B (fi)
IE (1) IE58890B1 (fi)
NO (1) NO166707C (fi)
PT (1) PT81251B (fi)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3522359A1 (de) * 1985-06-22 1987-01-02 Basf Ag Verfahren zum konfektionieren von kristallinen, organischen materialien
BE1002635A6 (nl) * 1988-12-09 1991-04-16 Amylum Nv Werkwijze voor het vervaardigen van een mengsel van zetmeel en polyvinylalcohol en aldus vervaardigd mengsel.
KR100291361B1 (ko) * 1992-10-14 2001-09-17 니뽄 신야쿠 가부시키가이샤 결정상태의전이방법
US5811547A (en) * 1992-10-14 1998-09-22 Nippon Shinyaju Co., Ltd. Method for inducing crystalline state transition in medicinal substance
FR2710637B1 (fr) * 1993-09-28 1995-12-08 Roquette Freres Mannitol pulvérulent de friabilité modérée et son procédé de préparation.
DE19541242A1 (de) 1995-11-06 1997-05-07 Hoechst Ag Lagerstabile Kunststoffadditive
US6235947B1 (en) * 1997-04-14 2001-05-22 Takeda Chemical Industries, Ltd. D-mannitol and its preparation
HUP9902165A3 (en) 1996-04-16 2001-01-29 Bayer Ag D-mannit and with big specific surface area process for preparing it and solid pharmaceuticals containing it
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
US7815937B2 (en) * 1998-10-27 2010-10-19 Biovail Laboratories International Srl Quick dissolve compositions and tablets based thereon
AU1323400A (en) * 1998-10-27 2000-05-15 Fuisz Technologies Ltd. Microparticles containing peg and/or peg glyceryl esters
CA2342121C (fr) * 2000-03-29 2010-05-25 Roquette Freres Mannitol pulverulent et son procede de preparation
WO2002007957A2 (en) * 2000-07-24 2002-01-31 Boehringer Ingelheim Pharmaceuticals, Inc. Apparatus and method for predicting the suitability of a substance for dry granulation by roller compaction using small sample sizes
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
DE10161402A1 (de) * 2001-12-13 2003-06-18 Merck Patent Gmbh Verfahren zur Herstellung von direkt tablettierbarem beta-Mannit
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US8545881B2 (en) 2004-04-19 2013-10-01 Eurand Pharmaceuticals, Ltd. Orally disintegrating tablets and methods of manufacture
JP5219507B2 (ja) * 2004-06-17 2013-06-26 カーギル インコーポレイテッド ポリオールの水蒸気凝集
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
NZ589750A (en) 2004-10-21 2012-07-27 Aptalis Pharmatech Inc Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
CN101166517B (zh) * 2005-05-10 2012-01-04 诺瓦提斯公司 制备含有可压性差的治疗性化合物的组合物的挤压方法
JP5400377B2 (ja) * 2005-05-10 2014-01-29 ノバルティス アーゲー 圧縮性に乏しい治療用化合物を有する組成物の製造法
CN100413834C (zh) * 2006-07-11 2008-08-27 广西南宁化学制药有限责任公司 一种可压缩颗粒甘露醇的制备方法
EP2183262A1 (en) * 2007-07-27 2010-05-12 Cargill, Incorporated Micronization of polyols
ES2668203T3 (es) 2009-12-02 2018-05-17 Adare Pharmaceuticals S.R.L. Microcápsulas de fexofenadina y composiciones que las contienen
CN103196284A (zh) * 2013-04-08 2013-07-10 马锡林 制粒式单锥干燥器
FR3038836B1 (fr) 2015-07-17 2017-07-14 Roquette Freres Granules de mannitol pour compression directe
CN110787722A (zh) * 2019-12-01 2020-02-14 浙江华康药业股份有限公司 一种结晶甘露醇干法造粒装置及工艺

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2951263A (en) * 1957-10-30 1960-09-06 Heyden Newport Chemical Corp Treatment of polyhydric alcohols
US3341415A (en) * 1964-02-12 1967-09-12 Warner Lambert Pharmaceutical Pharmaceutical tablet excipients of solid particles of a binary solid solution of mannitol with a sugar
US3966857A (en) * 1969-12-31 1976-06-29 Congoleum Industries, Inc. Lubrication of extruded materials
US4133857A (en) * 1975-09-16 1979-01-09 Chisso Corporation Method for producing a granular sorbic acid
JPS5220444A (en) * 1976-06-16 1977-02-16 Matsushita Electric Ind Co Ltd Extinguisher of liquid fuel combustor
JPS5365806A (en) * 1976-11-19 1978-06-12 Nippon Shiryo Kogyo Kk Method of making granular powder of crystalline sugar alcohol
US4302413A (en) * 1978-11-16 1981-11-24 Rogers Corporation Process for preparing extrudable polyimide granules
FR2451357A1 (fr) * 1979-03-16 1980-10-10 Roquette Freres Procede pour la mise sous forme comprimee du sorbitol et produit resultant
GB2054599B (en) * 1979-06-08 1983-03-16 Nat Res Dev Tableting of powder mixtures
DE3049196A1 (de) * 1980-12-24 1982-07-29 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von granulaten aus organischen in form einer schmelze vorliegenden stoffen
DE3245170A1 (de) * 1982-12-07 1984-06-07 Merck Patent Gmbh, 6100 Darmstadt Verbesserter sorbit, verfahren zur herstellung und verwendung
FR2588005B1 (fr) * 1985-10-02 1987-12-11 Roquette Freres Maltitol poudre directement compressible et son procede de preparation

Also Published As

Publication number Publication date
US5160680A (en) 1992-11-03
PT81251A (fr) 1985-11-01
GR852391B (fi) 1985-12-23
DE3564380D1 (en) 1988-09-22
FR2571046A1 (fr) 1986-04-04
KR930007408B1 (ko) 1993-08-10
DK450585A (da) 1986-04-04
IE58890B1 (en) 1993-12-01
IE852425L (en) 1986-04-03
PT81251B (pt) 1987-10-20
KR860002979A (ko) 1986-05-19
FI85367C (fi) 1992-04-10
FI85367B (fi) 1991-12-31
ES8700219A1 (es) 1986-10-01
FI853843A0 (fi) 1985-10-03
ES547529A0 (es) 1986-10-01
CA1272216A (en) 1990-07-31
ATE36466T1 (de) 1988-09-15
EP0177428B1 (fr) 1988-08-17
EP0177428A1 (fr) 1986-04-09
DK173282B1 (da) 2000-06-05
NO166707C (no) 1991-08-28
JPS61178943A (ja) 1986-08-11
FR2571046B1 (fr) 1987-10-16
CN85108629A (zh) 1986-07-23
DK450585D0 (da) 1985-10-03
CN1005963B (zh) 1989-12-06
NO166707B (no) 1991-05-21
NO853918L (no) 1986-04-04
JPH0643352B2 (ja) 1994-06-08

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: ROQUETTE FRERES

MA Patent expired