FI852851A7 - Mevalonolaktonin naftyylianalogeja ja niiden johdannaisia, menetelmiä niiden valmistamiseksi ja niiden käytt - Google Patents

Mevalonolaktonin naftyylianalogeja ja niiden johdannaisia, menetelmiä niiden valmistamiseksi ja niiden käytt Download PDF

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Publication number
FI852851A7
FI852851A7 FI852851A FI852851A FI852851A7 FI 852851 A7 FI852851 A7 FI 852851A7 FI 852851 A FI852851 A FI 852851A FI 852851 A FI852851 A FI 852851A FI 852851 A7 FI852851 A7 FI 852851A7
Authority
FI
Finland
Prior art keywords
mevalonolactone
derivatives
preparation
methods
naphthyl analogues
Prior art date
Application number
FI852851A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI852851L (fi
FI852851A0 (fi
Inventor
Paul Leroy Anderson
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of FI852851A0 publication Critical patent/FI852851A0/fi
Publication of FI852851L publication Critical patent/FI852851L/fi
Publication of FI852851A7 publication Critical patent/FI852851A7/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/38Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • C07C57/40Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic containing condensed ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/48Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30Oxygen atoms, e.g. delta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FI852851A 1984-07-24 1985-07-22 Mevalonolaktonin naftyylianalogeja ja niiden johdannaisia, menetelmiä niiden valmistamiseksi ja niiden käytt FI852851A7 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63380984A 1984-07-24 1984-07-24

Publications (3)

Publication Number Publication Date
FI852851A0 FI852851A0 (fi) 1985-07-22
FI852851L FI852851L (fi) 1986-01-25
FI852851A7 true FI852851A7 (fi) 1986-01-25

Family

ID=24541204

Family Applications (1)

Application Number Title Priority Date Filing Date
FI852851A FI852851A7 (fi) 1984-07-24 1985-07-22 Mevalonolaktonin naftyylianalogeja ja niiden johdannaisia, menetelmiä niiden valmistamiseksi ja niiden käytt

Country Status (21)

Country Link
JP (1) JPS6137754A (enrdf_load_stackoverflow)
KR (1) KR860001045A (enrdf_load_stackoverflow)
AU (1) AU4522685A (enrdf_load_stackoverflow)
BE (1) BE902914A (enrdf_load_stackoverflow)
DE (1) DE3525256A1 (enrdf_load_stackoverflow)
DK (1) DK333785A (enrdf_load_stackoverflow)
ES (1) ES8705356A1 (enrdf_load_stackoverflow)
FI (1) FI852851A7 (enrdf_load_stackoverflow)
FR (1) FR2568248A1 (enrdf_load_stackoverflow)
GB (1) GB2162179A (enrdf_load_stackoverflow)
GR (1) GR851805B (enrdf_load_stackoverflow)
HU (1) HUT39142A (enrdf_load_stackoverflow)
IL (1) IL75874A0 (enrdf_load_stackoverflow)
IT (1) IT1200095B (enrdf_load_stackoverflow)
LU (1) LU86012A1 (enrdf_load_stackoverflow)
NL (1) NL8502010A (enrdf_load_stackoverflow)
PH (1) PH21444A (enrdf_load_stackoverflow)
PL (1) PL254654A1 (enrdf_load_stackoverflow)
PT (1) PT80845B (enrdf_load_stackoverflow)
SE (1) SE8503556L (enrdf_load_stackoverflow)
ZA (1) ZA855594B (enrdf_load_stackoverflow)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5091378A (en) * 1987-05-22 1992-02-25 E. R. Squibb & Sons, Inc. Phosphorus-containing HMG-CoA reductase inhibitors, new intermediates and method
US4904646A (en) * 1987-05-22 1990-02-27 E. R. Squibb & Sons, Inc. Phosphorus-containing HMG-COA reductase inhibitors
DE3722807A1 (de) * 1987-07-10 1989-01-19 Hoechst Ag Neue 3,5-dihydroxycarbonsaeuren und deren derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
US4792614A (en) * 1987-08-05 1988-12-20 American Home Products Corporation Substituted furans as inhibitors of 3-hydroxy-3-methylglutaryl-coa reductase
US4812583A (en) * 1987-09-11 1989-03-14 American Home Products Corporation Substituted acyloxyalkylphenylethylene inhibitors of 3-hydroxy-3-methylglutaryl-coa reductase
DE3818570A1 (de) * 1988-06-01 1989-12-21 Boehringer Mannheim Gmbh Neue 6-substituierte-4-hydroxy-tetrahydro-pyran -2-on-derivate, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen
US5506219A (en) * 1988-08-29 1996-04-09 E. R. Squibb & Sons, Inc. Pyridine anchors for HMG-CoA reductase inhibitors
CA2185961A1 (en) * 1996-09-19 1998-03-20 K.S. Keshava Murthy Process for producing simvastatin
US20010006644A1 (en) 1997-07-31 2001-07-05 David J. Bova Combinations of hmg-coa reductase inhibitors and nicotinic acid and methods for treating hyperlipidemia once a day at night
KR100836960B1 (ko) 2007-09-07 2008-06-10 주식회사 서울제약 새로운 나이아신 제어방출형 제제

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55132595A (en) * 1979-04-04 1980-10-15 Nec Corp Semiconductor circuit

Also Published As

Publication number Publication date
KR860001045A (ko) 1986-02-22
DE3525256A1 (de) 1986-01-30
ZA855594B (en) 1987-02-25
IL75874A0 (en) 1985-11-29
BE902914A (fr) 1986-01-17
HUT39142A (en) 1986-08-28
GB8518490D0 (en) 1985-08-29
DK333785A (da) 1986-01-25
PT80845A (en) 1985-08-01
IT8548385A0 (it) 1985-07-23
FI852851L (fi) 1986-01-25
GR851805B (enrdf_load_stackoverflow) 1985-11-26
FR2568248A1 (fr) 1986-01-31
NL8502010A (nl) 1986-02-17
ES8705356A1 (es) 1987-05-01
SE8503556L (sv) 1986-01-25
PH21444A (en) 1987-10-20
IT1200095B (it) 1989-01-05
PL254654A1 (en) 1986-08-26
GB2162179A (en) 1986-01-29
AU4522685A (en) 1986-01-30
LU86012A1 (fr) 1986-02-12
DK333785D0 (da) 1985-07-22
FI852851A0 (fi) 1985-07-22
ES545454A0 (es) 1987-05-01
JPS6137754A (ja) 1986-02-22
PT80845B (en) 1987-03-24
SE8503556D0 (sv) 1985-07-22

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Owner name: SANDOZ AG