FI841601A0 - Prolin derivat. - Google Patents

Prolin derivat.

Info

Publication number
FI841601A0
FI841601A0 FI841601A FI841601A FI841601A0 FI 841601 A0 FI841601 A0 FI 841601A0 FI 841601 A FI841601 A FI 841601A FI 841601 A FI841601 A FI 841601A FI 841601 A0 FI841601 A0 FI 841601A0
Authority
FI
Finland
Prior art keywords
prolin
derivat
prolin derivat
Prior art date
Application number
FI841601A
Other languages
English (en)
Other versions
FI841601A (fi
Inventor
Anand Dutta
Ross Lee Stein
Diane Amy Trainor
Richard Alan Wildonger
Original Assignee
Ici America Inc
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838311423A external-priority patent/GB8311423D0/en
Priority claimed from GB838314708A external-priority patent/GB8314708D0/en
Application filed by Ici America Inc, Ici Plc filed Critical Ici America Inc
Publication of FI841601A0 publication Critical patent/FI841601A0/fi
Publication of FI841601A publication Critical patent/FI841601A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI841601A 1983-04-27 1984-04-24 Prolin-derivat. FI841601A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838311423A GB8311423D0 (en) 1983-04-27 1983-04-27 Proline derivatives
GB838314708A GB8314708D0 (en) 1983-05-27 1983-05-27 Proline derivatives

Publications (2)

Publication Number Publication Date
FI841601A0 true FI841601A0 (fi) 1984-04-24
FI841601A FI841601A (fi) 1984-10-28

Family

ID=26285956

Family Applications (1)

Application Number Title Priority Date Filing Date
FI841601A FI841601A (fi) 1983-04-27 1984-04-24 Prolin-derivat.

Country Status (15)

Country Link
US (2) US4596789A (fi)
EP (1) EP0124317B1 (fi)
AU (1) AU580955B2 (fi)
CA (1) CA1253297A (fi)
DE (1) DE3481913D1 (fi)
DK (1) DK209784A (fi)
ES (2) ES8701154A1 (fi)
FI (1) FI841601A (fi)
GR (1) GR81937B (fi)
HU (1) HUT34041A (fi)
IE (1) IE57350B1 (fi)
IL (1) IL71614A0 (fi)
NO (1) NO841665L (fi)
NZ (1) NZ207965A (fi)
PT (1) PT78502B (fi)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1267499A (en) * 1983-07-12 1990-04-03 Cedric H. Hassall Peptide amides and aldehydes
DD248961A1 (de) * 1984-05-22 1987-08-26 Akad Wissenschaften Ddr Verfahren zur herstellung wundheilungsfoerdernder praeparationen
US5055450A (en) * 1985-01-22 1991-10-08 Ici Americas Inc. Peptide derivatives
US5194588A (en) * 1985-01-22 1993-03-16 Ici Americas Inc. Aminoalcohol intermediates for peptide derivatives
GB8600263D0 (en) * 1985-01-22 1986-02-12 Ici America Inc Peptide derivatives
DE3683541D1 (de) * 1985-06-07 1992-03-05 Ici America Inc Selektionierte difluorverbindungen.
GB8613704D0 (en) * 1986-06-05 1986-07-09 Ici America Inc Difluoro keto compounds
EP0248562B1 (en) * 1986-06-05 1995-10-25 Zeneca Inc. Difluoro peptide compounds
ES2052560T3 (es) * 1986-06-05 1994-07-16 Ici America Inc Compuestos difluorcetonicos.
GB8809316D0 (en) * 1987-05-11 1988-05-25 Ici America Inc Heterocyclic ketones
JPH075634B2 (ja) * 1987-10-30 1995-01-25 日東紡績株式会社 トリペプチド類及びこれを含有する抗プラスミン剤
FR2622581B1 (fr) * 1987-11-03 1990-02-16 Inorgan Sa Rech Develop Pharm Nouveaux derives de l-proline, leur preparation et leurs applications biologiques
US5736520A (en) * 1988-10-07 1998-04-07 Merrell Pharmaceuticals Inc. Peptidase inhibitors
ZA897515B (en) * 1988-10-07 1990-06-27 Merrell Dow Pharma Novel peptidase inhibitors
JPH03503055A (ja) * 1988-10-27 1991-07-11 ユニバーシティー オブ ケンタッキー リサーチ ファウンデーション 人の白血球エラスターゼ阻害剤およびその製造方法およびその使用
EP0490379A3 (de) * 1990-12-13 1992-06-24 BERLIN-CHEMIE Aktiengesellschaft Diaminosäurederivate und pharmazeutische Zusammensetzungen
CA2071621C (en) * 1991-06-19 1996-08-06 Ahihiko Hosoda Aldehyde derivatives
IL108031A0 (en) * 1992-12-22 1994-04-12 Procter & Gamble Difluoro pentapeptide derivatives and pharmaceutical compositions containing them
FR2700165B1 (fr) * 1993-01-07 1995-02-17 Rhone Poulenc Rorer Sa Dérivés de pyrrolidine, leur préparation et les médicaments les contenant.
FR2700166B1 (fr) * 1993-01-07 1995-02-17 Rhone Poulenc Rorer Sa Dérivés de pyrrolidine, leur préparation et les médicaments les contenant.
US5436229A (en) * 1994-03-04 1995-07-25 Eli Lilly And Company Bisulfite adducts of arginine aldehydes
GB9502152D0 (en) * 1995-02-03 1995-03-29 Zeneca Ltd Proline derivatives
JP2002515860A (ja) * 1995-11-28 2002-05-28 セフアロン・インコーポレーテツド システイン及びセリンプロテアーゼのｄ―アミノ酸由来のインヒビター
EP0975353B1 (en) 1997-04-18 2005-11-09 Cephalon, Inc. Peptidyl-2-amino-1-hydroxyalkanesulfonic acid cysteine protease inhibitors
HUP0100100A3 (en) * 1997-08-11 2001-12-28 Boehringer Ingelheim Ca Ltd Hepatitis c inhibitor peptide analogues, pharmaceutical compositions comprising thereof and their use
CZ303213B6 (cs) * 2000-07-21 2012-05-23 Schering Corporation Peptidové inhibitory serinové proteázy NS3 a farmaceutický prostredek
US20030170617A1 (en) 2002-01-28 2003-09-11 Pasloske Brittan L. Crude biological derivatives competent for nucleic acid detection
PE20050204A1 (es) * 2003-05-21 2005-05-04 Boehringer Ingelheim Int Compuestos inhibidores de la hepatitis c
ATE512971T1 (de) * 2004-07-20 2011-07-15 Boehringer Ingelheim Int Peptidanaloga als hepatitis c-hemmer
UY29016A1 (es) 2004-07-20 2006-02-24 Boehringer Ingelheim Int Analogos de dipeptidos inhibidores de la hepatitis c
WO2008014252A2 (en) * 2006-07-24 2008-01-31 Tetralogic Pharmaceuticals Corporation Iap inhibitors
US7964350B1 (en) 2007-05-18 2011-06-21 Applied Biosystems, Llc Sample preparation for in situ nucleic acid analysis
US20080319221A1 (en) * 2007-06-22 2008-12-25 Bernd Junker Esters of Pentahydroxyhexylcarbamoyl Alkanoic Acids
DE102007063671A1 (de) * 2007-11-13 2009-06-25 Sanofi-Aventis Deutschland Gmbh Neue kristalline Diphenylazetidinonhydrate, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
EP2955233A1 (en) * 2008-12-19 2015-12-16 Life Technologies Corporation Proteinase K inhibitors, methods and compositions therefor
DK2726592T3 (en) * 2011-07-01 2015-07-06 Novozymes As stabilized subtilisinsammensætning
CN110799193B (zh) 2017-03-21 2023-12-12 斯克利普斯研究院 铜和镍催化的脱羧硼化反应
US20220267699A1 (en) 2019-07-01 2022-08-25 Basf Se Peptide acetals for stabilising enzymes

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE629254C (de) * 1934-06-28 1936-04-25 Fried Krupp Grusonwerk Akt Ges Vorrichtung zum Glaetten der Arbeitswalzen eines Walzwerks waehrend des Betriebes
US3867364A (en) * 1968-11-21 1975-02-18 Microbial Chem Res Found Process for the synthesis of leupeptins and their analogues
US3935280A (en) * 1975-01-10 1976-01-27 Aldrich-Boranes, Inc. Reduction of amino acids in the presence of boron trifluoride
CH629254A5 (en) * 1976-10-14 1982-04-15 Nippon Kayaku Kk Process for preparing L-leupeptins
HU177098B (en) * 1979-01-04 1981-07-28 Gyogyszerkutato Intezet Process for producing new peptidyl-n-carboxy-l-arginin-a
HU184368B (en) * 1981-01-13 1984-08-28 Gyogyszerkutato Intezet Process for preparing d-phenyl-alanyl-l-propyl-l-arginine-ald ehyde-shulphate
CS226907B1 (en) * 1981-08-07 1984-04-16 Kasafirek Evzen Alkylamides of carboxyalkanoylpeptides
FR2546164B1 (fr) * 1983-05-16 1987-07-17 Centre Nat Rech Scient Nouveaux derives de peptides, leur preparation et leur application comme inhibiteurs de l'elastase
CA1267499A (en) * 1983-07-12 1990-04-03 Cedric H. Hassall Peptide amides and aldehydes

Also Published As

Publication number Publication date
PT78502A (en) 1984-05-01
IE840985L (en) 1984-10-27
AU2744484A (en) 1984-11-01
PT78502B (en) 1986-07-22
IL71614A0 (en) 1984-07-31
ES8701154A1 (es) 1986-11-16
EP0124317A2 (en) 1984-11-07
IE57350B1 (en) 1992-08-12
US4691007A (en) 1987-09-01
ES532007A0 (es) 1986-11-16
EP0124317A3 (en) 1987-01-14
GR81937B (fi) 1984-12-12
DK209784A (da) 1984-10-28
NO841665L (no) 1984-10-29
NZ207965A (en) 1987-08-31
AU580955B2 (en) 1989-02-09
HUT34041A (en) 1985-01-28
DE3481913D1 (de) 1990-05-17
FI841601A (fi) 1984-10-28
EP0124317B1 (en) 1990-04-11
US4596789A (en) 1986-06-24
ES540029A0 (es) 1987-05-01
DK209784D0 (da) 1984-04-26
CA1253297A (en) 1989-04-25
ES8705465A1 (es) 1987-05-01

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: IMPERIAL CHEMICAL INDUSTRIES PLC

Owner name: ICI AMERICAS INC.