FI841601A - Prolin-derivat. - Google Patents
Prolin-derivat. Download PDFInfo
- Publication number
- FI841601A FI841601A FI841601A FI841601A FI841601A FI 841601 A FI841601 A FI 841601A FI 841601 A FI841601 A FI 841601A FI 841601 A FI841601 A FI 841601A FI 841601 A FI841601 A FI 841601A
- Authority
- FI
- Finland
- Prior art keywords
- derivate
- proline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1019—Tetrapeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB838311423A GB8311423D0 (en) | 1983-04-27 | 1983-04-27 | Proline derivatives |
GB838314708A GB8314708D0 (en) | 1983-05-27 | 1983-05-27 | Proline derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
FI841601A0 FI841601A0 (fi) | 1984-04-24 |
FI841601A true FI841601A (fi) | 1984-10-28 |
Family
ID=26285956
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI841601A FI841601A (fi) | 1983-04-27 | 1984-04-24 | Prolin-derivat. |
Country Status (15)
Country | Link |
---|---|
US (2) | US4596789A (fi) |
EP (1) | EP0124317B1 (fi) |
AU (1) | AU580955B2 (fi) |
CA (1) | CA1253297A (fi) |
DE (1) | DE3481913D1 (fi) |
DK (1) | DK209784A (fi) |
ES (2) | ES8701154A1 (fi) |
FI (1) | FI841601A (fi) |
GR (1) | GR81937B (fi) |
HU (1) | HUT34041A (fi) |
IE (1) | IE57350B1 (fi) |
IL (1) | IL71614A0 (fi) |
NO (1) | NO841665L (fi) |
NZ (1) | NZ207965A (fi) |
PT (1) | PT78502B (fi) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1267499A (en) * | 1983-07-12 | 1990-04-03 | Cedric H. Hassall | Peptide amides and aldehydes |
DD248961A1 (de) * | 1984-05-22 | 1987-08-26 | Akad Wissenschaften Ddr | Verfahren zur herstellung wundheilungsfoerdernder praeparationen |
GB8600263D0 (en) * | 1985-01-22 | 1986-02-12 | Ici America Inc | Peptide derivatives |
US5055450A (en) * | 1985-01-22 | 1991-10-08 | Ici Americas Inc. | Peptide derivatives |
US5194588A (en) * | 1985-01-22 | 1993-03-16 | Ici Americas Inc. | Aminoalcohol intermediates for peptide derivatives |
EP0204571B1 (en) | 1985-06-07 | 1992-01-22 | Ici Americas Inc. | Selected difluoro derivatives |
GB8613704D0 (en) * | 1986-06-05 | 1986-07-09 | Ici America Inc | Difluoro keto compounds |
DE3782191T2 (de) * | 1986-06-05 | 1993-02-25 | Ici America Inc | Difluorketoverbindungen. |
DE3751570T2 (de) * | 1986-06-05 | 1996-04-18 | Zeneca Inc | Difluoro-Peptid-Verbindungen. |
GB8809316D0 (en) * | 1987-05-11 | 1988-05-25 | Ici America Inc | Heterocyclic ketones |
JPH075634B2 (ja) * | 1987-10-30 | 1995-01-25 | 日東紡績株式会社 | トリペプチド類及びこれを含有する抗プラスミン剤 |
FR2622581B1 (fr) * | 1987-11-03 | 1990-02-16 | Inorgan Sa Rech Develop Pharm | Nouveaux derives de l-proline, leur preparation et leurs applications biologiques |
US5736520A (en) * | 1988-10-07 | 1998-04-07 | Merrell Pharmaceuticals Inc. | Peptidase inhibitors |
ZA897515B (en) * | 1988-10-07 | 1990-06-27 | Merrell Dow Pharma | Novel peptidase inhibitors |
JPH03503055A (ja) * | 1988-10-27 | 1991-07-11 | ユニバーシティー オブ ケンタッキー リサーチ ファウンデーション | 人の白血球エラスターゼ阻害剤およびその製造方法およびその使用 |
EP0490379A3 (de) * | 1990-12-13 | 1992-06-24 | BERLIN-CHEMIE Aktiengesellschaft | Diaminosäurederivate und pharmazeutische Zusammensetzungen |
CA2071621C (en) * | 1991-06-19 | 1996-08-06 | Ahihiko Hosoda | Aldehyde derivatives |
IL108031A0 (en) * | 1992-12-22 | 1994-04-12 | Procter & Gamble | Difluoro pentapeptide derivatives and pharmaceutical compositions containing them |
FR2700166B1 (fr) * | 1993-01-07 | 1995-02-17 | Rhone Poulenc Rorer Sa | Dérivés de pyrrolidine, leur préparation et les médicaments les contenant. |
FR2700165B1 (fr) * | 1993-01-07 | 1995-02-17 | Rhone Poulenc Rorer Sa | Dérivés de pyrrolidine, leur préparation et les médicaments les contenant. |
US5436229A (en) * | 1994-03-04 | 1995-07-25 | Eli Lilly And Company | Bisulfite adducts of arginine aldehydes |
GB9502152D0 (en) * | 1995-02-03 | 1995-03-29 | Zeneca Ltd | Proline derivatives |
KR100490807B1 (ko) * | 1995-11-28 | 2005-10-14 | 세파론, 인코포레이티드 | 시스테인및세린프로테아제의d-아미노산함유억제제 |
DE69832268T2 (de) | 1997-04-18 | 2006-07-13 | Cephalon, Inc. | Peptidyl2-amino-1hydroxyalkansulfonsäuren als zysteinprotease-inhibitoren |
ES2234144T3 (es) * | 1997-08-11 | 2005-06-16 | Boehringer Ingelheim (Canada) Ltd. | Analogos de peptidos inhibidores de la hepatitis c. |
IL153670A0 (en) * | 2000-07-21 | 2003-07-06 | Schering Corp | Novel peptides as ns3-serine protease inhibitors of hepatitis c virus |
EP2290098A1 (en) | 2002-01-28 | 2011-03-02 | Ambion, Inc. | Preparing crude biological extracts using protease, suitable for preparing cDNA |
AU2004240704B9 (en) * | 2003-05-21 | 2009-10-22 | Boehringer Ingelheim International Gmbh | Hepatitis C inhibitor compounds |
ES2366478T3 (es) * | 2004-07-20 | 2011-10-20 | Boehringer Ingelheim International Gmbh | Análogos peptídicos inhibidores de la hepatitis c. |
UY29016A1 (es) * | 2004-07-20 | 2006-02-24 | Boehringer Ingelheim Int | Analogos de dipeptidos inhibidores de la hepatitis c |
AR064235A1 (es) * | 2006-07-24 | 2009-03-25 | Tetralogic Pharmaceuticals Cor | Dipeptidos antagonistas de iap, una composicion farmaceutica que los comprende y el uso de los mismos para el tratamiento del cancer |
US7964350B1 (en) | 2007-05-18 | 2011-06-21 | Applied Biosystems, Llc | Sample preparation for in situ nucleic acid analysis |
US20080319221A1 (en) * | 2007-06-22 | 2008-12-25 | Bernd Junker | Esters of Pentahydroxyhexylcarbamoyl Alkanoic Acids |
DE102007054497B3 (de) * | 2007-11-13 | 2009-07-23 | Sanofi-Aventis Deutschland Gmbh | Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung |
EP2955233A1 (en) | 2008-12-19 | 2015-12-16 | Life Technologies Corporation | Proteinase K inhibitors, methods and compositions therefor |
EP2726592B1 (en) * | 2011-07-01 | 2015-04-01 | Novozymes A/S | Stabilized subtilisin composition |
CN110799193B (zh) | 2017-03-21 | 2023-12-12 | 斯克利普斯研究院 | 铜和镍催化的脱羧硼化反应 |
CN114008068A (zh) | 2019-07-01 | 2022-02-01 | 巴斯夫欧洲公司 | 稳定酶的肽缩醛 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE629254C (de) * | 1934-06-28 | 1936-04-25 | Fried Krupp Grusonwerk Akt Ges | Vorrichtung zum Glaetten der Arbeitswalzen eines Walzwerks waehrend des Betriebes |
US3867364A (en) * | 1968-11-21 | 1975-02-18 | Microbial Chem Res Found | Process for the synthesis of leupeptins and their analogues |
US3935280A (en) * | 1975-01-10 | 1976-01-27 | Aldrich-Boranes, Inc. | Reduction of amino acids in the presence of boron trifluoride |
CH629254A5 (en) * | 1976-10-14 | 1982-04-15 | Nippon Kayaku Kk | Process for preparing L-leupeptins |
HU177098B (en) * | 1979-01-04 | 1981-07-28 | Gyogyszerkutato Intezet | Process for producing new peptidyl-n-carboxy-l-arginin-a |
HU184368B (en) * | 1981-01-13 | 1984-08-28 | Gyogyszerkutato Intezet | Process for preparing d-phenyl-alanyl-l-propyl-l-arginine-ald ehyde-shulphate |
CS226907B1 (en) * | 1981-08-07 | 1984-04-16 | Kasafirek Evzen | Alkylamides of carboxyalkanoylpeptides |
FR2546164B1 (fr) * | 1983-05-16 | 1987-07-17 | Centre Nat Rech Scient | Nouveaux derives de peptides, leur preparation et leur application comme inhibiteurs de l'elastase |
CA1267499A (en) * | 1983-07-12 | 1990-04-03 | Cedric H. Hassall | Peptide amides and aldehydes |
-
1984
- 1984-04-17 EP EP84302621A patent/EP0124317B1/en not_active Expired
- 1984-04-17 DE DE8484302621T patent/DE3481913D1/de not_active Expired - Fee Related
- 1984-04-19 IE IE985/84A patent/IE57350B1/en not_active IP Right Cessation
- 1984-04-22 IL IL71614A patent/IL71614A0/xx unknown
- 1984-04-24 GR GR74482A patent/GR81937B/el unknown
- 1984-04-24 FI FI841601A patent/FI841601A/fi not_active Application Discontinuation
- 1984-04-24 US US06/603,408 patent/US4596789A/en not_active Expired - Lifetime
- 1984-04-25 HU HU841586A patent/HUT34041A/hu unknown
- 1984-04-25 CA CA000452712A patent/CA1253297A/en not_active Expired
- 1984-04-26 NZ NZ207965A patent/NZ207965A/en unknown
- 1984-04-26 DK DK209784A patent/DK209784A/da not_active Application Discontinuation
- 1984-04-26 NO NO841665A patent/NO841665L/no unknown
- 1984-04-27 AU AU27444/84A patent/AU580955B2/en not_active Ceased
- 1984-04-27 ES ES532007A patent/ES8701154A1/es not_active Expired
- 1984-04-27 PT PT78502A patent/PT78502B/pt not_active IP Right Cessation
-
1985
- 1985-01-31 ES ES540029A patent/ES8705465A1/es not_active Expired
- 1985-12-06 US US06/806,265 patent/US4691007A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
NZ207965A (en) | 1987-08-31 |
IE57350B1 (en) | 1992-08-12 |
IL71614A0 (en) | 1984-07-31 |
CA1253297A (en) | 1989-04-25 |
AU2744484A (en) | 1984-11-01 |
EP0124317B1 (en) | 1990-04-11 |
GR81937B (fi) | 1984-12-12 |
DK209784A (da) | 1984-10-28 |
EP0124317A3 (en) | 1987-01-14 |
DK209784D0 (da) | 1984-04-26 |
AU580955B2 (en) | 1989-02-09 |
FI841601A0 (fi) | 1984-04-24 |
ES8701154A1 (es) | 1986-11-16 |
IE840985L (en) | 1984-10-27 |
ES532007A0 (es) | 1986-11-16 |
DE3481913D1 (de) | 1990-05-17 |
ES8705465A1 (es) | 1987-05-01 |
ES540029A0 (es) | 1987-05-01 |
US4691007A (en) | 1987-09-01 |
EP0124317A2 (en) | 1984-11-07 |
HUT34041A (en) | 1985-01-28 |
PT78502A (en) | 1984-05-01 |
PT78502B (en) | 1986-07-22 |
NO841665L (no) | 1984-10-29 |
US4596789A (en) | 1986-06-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed |
Owner name: IMPERIAL CHEMICAL INDUSTRIES PLC Owner name: ICI AMERICAS INC. |