FI840463A - Vissa bensazokinon- och bensazoninonderivat. - Google Patents
Vissa bensazokinon- och bensazoninonderivat. Download PDFInfo
- Publication number
- FI840463A FI840463A FI840463A FI840463A FI840463A FI 840463 A FI840463 A FI 840463A FI 840463 A FI840463 A FI 840463A FI 840463 A FI840463 A FI 840463A FI 840463 A FI840463 A FI 840463A
- Authority
- FI
- Finland
- Prior art keywords
- bensazoninonderivat
- bensazokinon
- vissa
- och
- benzazonin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/465,696 US4470988A (en) | 1983-02-10 | 1983-02-10 | Benzazocinone and benzazoninone derivatives, and their pharmaceutical use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI840463A0 FI840463A0 (fi) | 1984-02-06 |
| FI840463A true FI840463A (fi) | 1984-08-11 |
Family
ID=23848809
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI840463A FI840463A (fi) | 1983-02-10 | 1984-02-06 | Vissa bensazokinon- och bensazoninonderivat. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US4470988A (fi) |
| EP (1) | EP0119161B1 (fi) |
| JP (1) | JPS59172474A (fi) |
| KR (1) | KR840007872A (fi) |
| AT (1) | ATE44279T1 (fi) |
| AU (1) | AU2443184A (fi) |
| CA (1) | CA1218989A (fi) |
| DD (1) | DD216717A5 (fi) |
| DE (1) | DE3478810D1 (fi) |
| DK (1) | DK58084A (fi) |
| ES (2) | ES8606286A1 (fi) |
| FI (1) | FI840463A (fi) |
| GR (1) | GR81766B (fi) |
| HU (1) | HU193671B (fi) |
| IE (1) | IE56816B1 (fi) |
| IL (1) | IL70882A0 (fi) |
| NO (1) | NO840486L (fi) |
| NZ (1) | NZ207090A (fi) |
| PT (1) | PT78064B (fi) |
| ZA (1) | ZA84959B (fi) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4873235A (en) * | 1982-06-01 | 1989-10-10 | Merck & Co., Inc. | Benzofused lactams as antihypertensives |
| US4537885A (en) * | 1983-02-10 | 1985-08-27 | Ciba Geigy Corporation | Certain benzazocinone and benzazoninone derivatives |
| EP0166357A3 (en) * | 1984-06-26 | 1988-10-26 | Merck & Co. Inc. | Benzofused lactams and pharmaceutical compositions containing them |
| EP0166354B1 (en) * | 1984-06-26 | 1992-08-05 | Merck & Co. Inc. | Benzofused lactam compounds and pharmaceutical compositions containing them |
| US4692522A (en) * | 1985-04-01 | 1987-09-08 | Merck & Co., Inc. | Benzofused lactams useful as cholecystokinin antagonists |
| US4785089A (en) * | 1985-06-13 | 1988-11-15 | Ciba-Geigy Corporation | Novel sulfonic acid esters and their preparation |
| DE3704661A1 (de) * | 1987-02-14 | 1988-08-25 | Hoechst Ag | Annelierte azepinon- und azocinon-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung, sowie zwischenprodukte bei ihrer herstellung |
| US5145864A (en) * | 1987-09-15 | 1992-09-08 | Alcoholism And Drug Addiction Research Foundation | Reduction of voluntary alcohol consumption by treatment with angiotensin converting enzyme inhibitors |
| US5110813A (en) * | 1987-09-15 | 1992-05-05 | Alcoholism And Drug Addiction Research Foundation | Reduction of voluntary alcohol consumption by treatment with angiotensin converting enzyme inhibitors |
| US5428031A (en) * | 1991-12-03 | 1995-06-27 | Merck & Co., Inc. | Methods of treating cardiac arrhythmia |
| US5552397A (en) * | 1992-05-18 | 1996-09-03 | E. R. Squibb & Sons, Inc. | Substituted azepinone dual inhibitors of angiotensin converting enzyme and neutral exdopeptidase |
| RU2124503C1 (ru) | 1992-05-18 | 1999-01-10 | И.Р.Сквибб энд Санз, Инк. | Гетероциклические азотсодержащие производные карбоновой кислоты, способ их получения и фармацевтическая композиция |
| US5654294A (en) * | 1993-05-13 | 1997-08-05 | Bristol-Myers Squibb | Spiro lactam dual action inhibitors |
| ATE206402T1 (de) * | 1993-11-22 | 2001-10-15 | Merck & Co Inc | 3-acylaminobenzazepine |
| HU220635B1 (hu) * | 1994-08-18 | 2002-03-28 | Merck & Co. Inc. | 2,3-Dihidro-1-(2,2,2-trifluor-etil)-2-oxo-5-fenil-1H-1,4-benzodiazepin-származékok, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk gyógyszerkészítmények előállítására |
| US5587375A (en) * | 1995-02-17 | 1996-12-24 | Bristol-Myers Squibb Company | Azepinone compounds useful in the inhibition of ACE and NEP |
| US5877313A (en) * | 1995-05-17 | 1999-03-02 | Bristol-Myers Squibb | Benzo-fused azepinone and piperidinone compounds useful in the inhibition of ACE and NEP |
| US5650408A (en) * | 1995-06-07 | 1997-07-22 | Karanewsky; Donald S. | Thiazolo benzazepine containing dual action inhibitors |
| JPH11506760A (ja) * | 1995-06-07 | 1999-06-15 | メルク エンド カンパニー インコーポレーテッド | 新規なｎ−（２，４−ジオキソ−２，３，４，５−テトラヒドロ−１ｈ−１，５−ベンゾジアゼピン−３イル）−３−アミド |
| US5631251A (en) * | 1995-06-07 | 1997-05-20 | Merck & Co., Inc. | 5-cyclopropyl-1,4 benzodiazepine-2-ones |
| US5726171A (en) * | 1995-06-07 | 1998-03-10 | Merck & Co Inc | N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo B! 1,4!diazepin-3yl)-acetamides |
| US5691331A (en) * | 1995-06-07 | 1997-11-25 | Merck & Co., Inc. | N-(2,4-Dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3yl) -3- amides |
| US5635504A (en) * | 1995-06-07 | 1997-06-03 | Bristol-Myers Squibb Co. | Diazepine containing dual action inhibitors |
| US5700797A (en) * | 1995-06-07 | 1997-12-23 | Merck & Co, Inc. | N-(2,4-dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl)-3-amides |
| EP2544765A1 (en) | 2010-03-11 | 2013-01-16 | Merck Patent GmbH | Fibers in therapy and cosmetics |
| WO2023178538A1 (zh) * | 2022-03-23 | 2023-09-28 | 浙江华海药业股份有限公司 | 一种纯化左乙拉西坦中间体的方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3395150A (en) * | 1965-02-26 | 1968-07-30 | Squibb & Sons Inc | Benzothiazepine carboxamides and derivatives thereof |
| GB1191963A (en) * | 1968-02-07 | 1970-05-13 | Ucb Sa | Heterocyclic Compounds |
| GB1183442A (fi) * | 1968-02-23 | 1970-03-04 | ||
| LU79008A1 (de) * | 1978-02-03 | 1979-09-06 | Byk Gulden Lomberg Chem Fab | W-(n-alkyl-n-benzoyl-amino)-phenylalkansaeuren,ihre verwendung und herstellung sowie sie enthaltende arzneimittel |
| PT73522B (en) * | 1980-08-18 | 1983-07-14 | Merck & Co Inc | Process for preparing substituted caprylolactam derivatives as antihypertensives |
| IL63540A0 (en) * | 1980-08-18 | 1981-11-30 | Merck & Co Inc | Substituted enantholactam derivatives as antihypertensives |
| GR74635B (fi) * | 1980-08-18 | 1984-06-29 | Merck & Co Inc | |
| US4410520A (en) * | 1981-11-09 | 1983-10-18 | Ciba-Geigy Corporation | 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids |
| EP0107095B1 (en) * | 1982-09-30 | 1987-09-09 | Merck & Co. Inc. | 1-n-alkylcarboxy-benzofused lactams useful as antihypertensive agents |
-
1983
- 1983-02-10 US US06/465,696 patent/US4470988A/en not_active Expired - Lifetime
-
1984
- 1984-02-06 EP EP84810068A patent/EP0119161B1/de not_active Expired
- 1984-02-06 FI FI840463A patent/FI840463A/fi not_active Application Discontinuation
- 1984-02-06 AT AT84810068T patent/ATE44279T1/de active
- 1984-02-06 PT PT78064A patent/PT78064B/pt not_active IP Right Cessation
- 1984-02-06 DE DE8484810068T patent/DE3478810D1/de not_active Expired
- 1984-02-07 IL IL70882A patent/IL70882A0/xx unknown
- 1984-02-08 CA CA000446969A patent/CA1218989A/en not_active Expired
- 1984-02-08 GR GR73755A patent/GR81766B/el unknown
- 1984-02-09 JP JP59020906A patent/JPS59172474A/ja active Granted
- 1984-02-09 DK DK58084A patent/DK58084A/da not_active Application Discontinuation
- 1984-02-09 DD DD84259963A patent/DD216717A5/de unknown
- 1984-02-09 HU HU84524A patent/HU193671B/hu unknown
- 1984-02-09 NO NO840486A patent/NO840486L/no unknown
- 1984-02-09 ES ES529593A patent/ES8606286A1/es not_active Expired
- 1984-02-09 NZ NZ207090A patent/NZ207090A/en unknown
- 1984-02-09 AU AU24431/84A patent/AU2443184A/en not_active Abandoned
- 1984-02-09 ZA ZA84959A patent/ZA84959B/xx unknown
- 1984-02-09 IE IE301/84A patent/IE56816B1/en not_active IP Right Cessation
- 1984-02-10 KR KR1019840000631A patent/KR840007872A/ko not_active Application Discontinuation
-
1985
- 1985-06-11 ES ES544051A patent/ES8700240A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE3478810D1 (en) | 1989-08-03 |
| IE56816B1 (en) | 1991-12-18 |
| KR840007872A (ko) | 1984-12-11 |
| AU2443184A (en) | 1984-08-16 |
| PT78064B (en) | 1986-06-02 |
| ATE44279T1 (de) | 1989-07-15 |
| CA1218989A (en) | 1987-03-10 |
| FI840463A0 (fi) | 1984-02-06 |
| PT78064A (en) | 1984-03-01 |
| DK58084D0 (da) | 1984-02-09 |
| IE840301L (en) | 1984-08-10 |
| IL70882A0 (en) | 1984-05-31 |
| HU193671B (en) | 1987-11-30 |
| NO840486L (no) | 1984-08-13 |
| EP0119161A2 (de) | 1984-09-19 |
| EP0119161A3 (en) | 1986-06-11 |
| EP0119161B1 (de) | 1989-06-28 |
| NZ207090A (en) | 1985-10-11 |
| JPH0449545B2 (fi) | 1992-08-11 |
| JPS59172474A (ja) | 1984-09-29 |
| DD216717A5 (de) | 1984-12-19 |
| ES8606286A1 (es) | 1986-04-01 |
| DK58084A (da) | 1984-08-11 |
| ZA84959B (en) | 1984-09-26 |
| GR81766B (fi) | 1984-12-12 |
| ES529593A0 (es) | 1986-04-01 |
| ES8700240A1 (es) | 1986-09-16 |
| US4470988A (en) | 1984-09-11 |
| ES544051A0 (es) | 1986-09-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed |
Owner name: CIBA-GEIGY AG |