FI813349L - 1-karboxialkanoyl-indolin-2-karboxylsyror foerfaranden foer deras framstaellning farmaceutiska preparat innehaollande dessa foereningar samt deras terapeutiska anvaendning - Google Patents

1-karboxialkanoyl-indolin-2-karboxylsyror foerfaranden foer deras framstaellning farmaceutiska preparat innehaollande dessa foereningar samt deras terapeutiska anvaendning

Info

Publication number
FI813349L
FI813349L FI813349A FI813349A FI813349L FI 813349 L FI813349 L FI 813349L FI 813349 A FI813349 A FI 813349A FI 813349 A FI813349 A FI 813349A FI 813349 L FI813349 L FI 813349L
Authority
FI
Finland
Prior art keywords
carboxylsyror
carboxykanoyl
indolin
pharmaceuticals
preparation
Prior art date
Application number
FI813349A
Other languages
English (en)
Finnish (fi)
Inventor
Norbert Gruenfeld
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI813349L publication Critical patent/FI813349L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI813349A 1980-10-27 1981-10-26 1-karboxialkanoyl-indolin-2-karboxylsyror foerfaranden foer deras framstaellning farmaceutiska preparat innehaollande dessa foereningar samt deras terapeutiska anvaendning FI813349L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20070680A 1980-10-27 1980-10-27
US06/235,294 US4374847A (en) 1980-10-27 1981-02-17 1-Carboxyalkanoylindoline-2-carboxylic acids

Publications (1)

Publication Number Publication Date
FI813349L true FI813349L (fi) 1982-04-28

Family

ID=26896021

Family Applications (1)

Application Number Title Priority Date Filing Date
FI813349A FI813349L (fi) 1980-10-27 1981-10-26 1-karboxialkanoyl-indolin-2-karboxylsyror foerfaranden foer deras framstaellning farmaceutiska preparat innehaollande dessa foereningar samt deras terapeutiska anvaendning

Country Status (22)

Country Link
US (1) US4374847A (no)
EP (1) EP0050850B1 (no)
KR (1) KR890000662B1 (no)
AT (1) ATE26705T1 (no)
AU (1) AU546726B2 (no)
CA (1) CA1172257A (no)
CY (1) CY1380A (no)
DD (1) DD201887A5 (no)
DE (1) DE3176125D1 (no)
DK (1) DK154978C (no)
ES (2) ES506571A0 (no)
FI (1) FI813349L (no)
GB (1) GB2085880B (no)
GR (1) GR74690B (no)
HK (1) HK84687A (no)
HU (1) HU185151B (no)
IE (1) IE51688B1 (no)
IL (1) IL64111A (no)
MY (1) MY8700568A (no)
NO (1) NO156979C (no)
NZ (1) NZ198750A (no)
PT (1) PT73879B (no)

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US4645857A (en) * 1985-02-11 1987-02-24 American Home Products Corporation Process for preparing indoline-2-carboxylic acids via α-hydroxy-2-nitrobenzenepropanoic acid
JPH0623190B2 (ja) * 1985-04-16 1994-03-30 サントリー株式会社 インヒビタ−活性を有するｎ−アシルピロリジン誘導体及びその製法並びに用途
US4785089A (en) * 1985-06-13 1988-11-15 Ciba-Geigy Corporation Novel sulfonic acid esters and their preparation
KR880001848B1 (ko) * 1985-07-04 1988-09-22 재단법인 한국화학연구소 인돌린 유도체의 제조방법
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DE3536687A1 (de) * 1985-10-15 1987-04-16 Hoechst Ag Verfahren zur behandlung von atherosklerose, thrombose und der peripheren gefaesskrankheit
EP0225292A3 (en) * 1985-12-06 1988-11-30 Ciba-Geigy Ag Certain n-substituted butyramide derivatives
US5166212A (en) * 1985-12-06 1992-11-24 Ciba-Geigy Corporation Certain n-substituted butyramide derivatives
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EP0254032A3 (en) 1986-06-20 1990-09-05 Schering Corporation Neutral metalloendopeptidase inhibitors in the treatment of hypertension
EP0566157A1 (en) 1986-06-20 1993-10-20 Schering Corporation Neutral metalloendopeptidase inhibitors in the treatment of hypertension
DE3633496A1 (de) * 1986-10-02 1988-04-14 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
DE3639879A1 (de) * 1986-11-21 1988-06-01 Hoechst Ag Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren, zwischenprodukte dieses verfahrens sowie ein verfahren zu deren herstellung
US5262436A (en) * 1987-03-27 1993-11-16 Schering Corporation Acylamino acid antihypertensives in the treatment of congestive heart failure
DE3722007A1 (de) * 1987-07-03 1989-01-12 Hoechst Ag Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung
HU904967D0 (en) * 1988-04-22 1991-01-28 Hoechst Ag Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives
DD284030A5 (de) 1988-11-24 1990-10-31 Hoechst Ag,De Verfahren zur herstellung von peptiden mit bradykinin-antagonistischer wirkung
ZA902661B (en) * 1989-04-10 1991-01-30 Schering Corp Mercapto-acyl amino acids
JPH075530B2 (ja) * 1989-11-21 1995-01-25 シェリング・コーポレーション カルボキシアルキルカルボニルアミノ酸エンドペプチダーゼ阻害剤
AU7168091A (en) * 1989-12-22 1991-07-24 Schering Corporation Mercaptocycloacyl aminoacid endopeptidase inhibitors
US5075302A (en) * 1990-03-09 1991-12-24 Schering Corporation Mercaptoacyl aminolactam endopeptidase inhibitors
US5173506A (en) * 1990-08-16 1992-12-22 Schering Corporation N-(mercaptoalkyl)ureas and carbamates
TW197945B (no) * 1990-11-27 1993-01-11 Hoechst Ag
TW258739B (no) * 1992-04-04 1995-10-01 Hoechst Ag
EP0739898B1 (de) * 1995-03-13 2001-09-26 Aventis Pharma Deutschland GmbH Phosphonomonoesternnukleinsäuren, Verfahren zu ihrer Herstellung und ihre Verwendung
AU7381196A (en) * 1995-09-28 1997-04-17 Merck & Co., Inc. Preparation of carboxyalkyl derivatives
FR2746394B1 (fr) 1996-03-20 1998-05-29 Roussel Uclaf Nouveaux composes tricycliques, leur procede de preparation, et les intermediaires de ce procede, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
PT796855E (pt) 1996-03-20 2002-07-31 Hoechst Ag Inibicao da reabsorcao nos ossos e antagonistas de vitronectina
DE19612067A1 (de) * 1996-03-27 1997-10-02 Hoechst Ag Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von chronisch fibrogenetischen Lebererkrankungen und akuten Lebererkrankungen
DE19653647A1 (de) 1996-12-20 1998-06-25 Hoechst Ag Vitronectin - Rezeptorantagonisten, deren Herstellung sowie deren Verwendung
DE19741235A1 (de) * 1997-09-18 1999-03-25 Hoechst Marion Roussel De Gmbh Neue Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19741873A1 (de) * 1997-09-23 1999-03-25 Hoechst Marion Roussel De Gmbh Neue 5-Ring-Heterocyclen, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
DE19751251A1 (de) 1997-11-19 1999-05-20 Hoechst Marion Roussel De Gmbh Substituierte Imidazolidinderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmezeutische Präparate
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CA2521364A1 (en) * 2003-04-15 2004-10-28 Warner-Lambert Company Llc [c]-fused bicyclic proline derivatives and their use for treating arthritic conditions
CA2522195A1 (en) * 2003-04-15 2004-10-28 Warner-Lambert Company Llc [b]-fused bicyclic proline derivatives and their use for treating arthritic conditions

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Also Published As

Publication number Publication date
NO156979C (no) 1987-12-30
AU546726B2 (en) 1985-09-19
EP0050850B1 (de) 1987-04-22
GB2085880A (en) 1982-05-06
HK84687A (en) 1987-11-20
ES8401027A1 (es) 1983-12-01
GB2085880B (en) 1984-05-31
IL64111A0 (no) 1982-01-31
DK154978C (da) 1989-06-12
ES516561A0 (es) 1983-12-01
KR890000662B1 (ko) 1989-03-22
NZ198750A (en) 1984-05-31
AU7682381A (en) 1982-05-06
DK470481A (da) 1982-04-28
DK154978B (da) 1989-01-16
ES8303334A1 (es) 1983-02-01
NO813615L (no) 1982-04-28
IL64111A (en) 1984-10-31
ATE26705T1 (de) 1987-05-15
NO156979B (no) 1987-09-21
DE3176125D1 (en) 1987-05-27
GR74690B (no) 1984-07-03
ES506571A0 (es) 1983-02-01
US4374847A (en) 1983-02-22
PT73879A (de) 1981-11-01
MY8700568A (en) 1987-12-31
IE51688B1 (en) 1987-02-04
KR830007551A (ko) 1983-10-21
PT73879B (de) 1983-10-25
HU185151B (en) 1984-12-28
EP0050850A1 (de) 1982-05-05
CY1380A (en) 1987-08-07
CA1172257A (en) 1984-08-07
DD201887A5 (de) 1983-08-17

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Owner name: CIBA-GEIGY AG