DK154978C - Analogifremgangsmaade til fremstilling af 1-carboxy-(alkanoyl eller aralkanoyl)-indolin-2-carboxylsyrederivater eller stereoisomere salte deraf - Google Patents

Analogifremgangsmaade til fremstilling af 1-carboxy-(alkanoyl eller aralkanoyl)-indolin-2-carboxylsyrederivater eller stereoisomere salte deraf

Info

Publication number
DK154978C
DK154978C DK470481A DK470481A DK154978C DK 154978 C DK154978 C DK 154978C DK 470481 A DK470481 A DK 470481A DK 470481 A DK470481 A DK 470481A DK 154978 C DK154978 C DK 154978C
Authority
DK
Denmark
Prior art keywords
aralkanoyl
indoline
alkanoyl
carboxy
analogy
Prior art date
Application number
DK470481A
Other languages
English (en)
Other versions
DK154978B (da
DK470481A (da
Inventor
Norbert Gruenfeld
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK470481A publication Critical patent/DK470481A/da
Publication of DK154978B publication Critical patent/DK154978B/da
Application granted granted Critical
Publication of DK154978C publication Critical patent/DK154978C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK470481A 1980-10-27 1981-10-26 Analogifremgangsmaade til fremstilling af 1-carboxy-(alkanoyl eller aralkanoyl)-indolin-2-carboxylsyrederivater eller stereoisomere salte deraf DK154978C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US20070680A 1980-10-27 1980-10-27
US20070680 1980-10-27
US23529481 1981-02-17
US06/235,294 US4374847A (en) 1980-10-27 1981-02-17 1-Carboxyalkanoylindoline-2-carboxylic acids

Publications (3)

Publication Number Publication Date
DK470481A DK470481A (da) 1982-04-28
DK154978B DK154978B (da) 1989-01-16
DK154978C true DK154978C (da) 1989-06-12

Family

ID=26896021

Family Applications (1)

Application Number Title Priority Date Filing Date
DK470481A DK154978C (da) 1980-10-27 1981-10-26 Analogifremgangsmaade til fremstilling af 1-carboxy-(alkanoyl eller aralkanoyl)-indolin-2-carboxylsyrederivater eller stereoisomere salte deraf

Country Status (22)

Country Link
US (1) US4374847A (da)
EP (1) EP0050850B1 (da)
KR (1) KR890000662B1 (da)
AT (1) ATE26705T1 (da)
AU (1) AU546726B2 (da)
CA (1) CA1172257A (da)
CY (1) CY1380A (da)
DD (1) DD201887A5 (da)
DE (1) DE3176125D1 (da)
DK (1) DK154978C (da)
ES (2) ES8303334A1 (da)
FI (1) FI813349L (da)
GB (1) GB2085880B (da)
GR (1) GR74690B (da)
HK (1) HK84687A (da)
HU (1) HU185151B (da)
IE (1) IE51688B1 (da)
IL (1) IL64111A (da)
MY (1) MY8700568A (da)
NO (1) NO156979C (da)
NZ (1) NZ198750A (da)
PT (1) PT73879B (da)

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JPH0623190B2 (ja) * 1985-04-16 1994-03-30 サントリー株式会社 インヒビタ−活性を有するｎ−アシルピロリジン誘導体及びその製法並びに用途
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DE3536687A1 (de) * 1985-10-15 1987-04-16 Hoechst Ag Verfahren zur behandlung von atherosklerose, thrombose und der peripheren gefaesskrankheit
US5231080A (en) * 1985-10-15 1993-07-27 Hoechst Aktiengesellschaft Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease
EP0225292A3 (en) * 1985-12-06 1988-11-30 Ciba-Geigy Ag Certain n-substituted butyramide derivatives
US5166212A (en) * 1985-12-06 1992-11-24 Ciba-Geigy Corporation Certain n-substituted butyramide derivatives
US5231084A (en) * 1986-03-27 1993-07-27 Hoechst Aktiengesellschaft Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
EP0254032A3 (en) * 1986-06-20 1990-09-05 Schering Corporation Neutral metalloendopeptidase inhibitors in the treatment of hypertension
EP0566157A1 (en) 1986-06-20 1993-10-20 Schering Corporation Neutral metalloendopeptidase inhibitors in the treatment of hypertension
DE3633496A1 (de) * 1986-10-02 1988-04-14 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
DE3639879A1 (de) * 1986-11-21 1988-06-01 Hoechst Ag Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren, zwischenprodukte dieses verfahrens sowie ein verfahren zu deren herstellung
US5262436A (en) * 1987-03-27 1993-11-16 Schering Corporation Acylamino acid antihypertensives in the treatment of congestive heart failure
DE3722007A1 (de) * 1987-07-03 1989-01-12 Hoechst Ag Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung
HU904967D0 (en) * 1988-04-22 1991-01-28 Hoechst Ag Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives
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ZA902661B (en) * 1989-04-10 1991-01-30 Schering Corp Mercapto-acyl amino acids
JPH075530B2 (ja) * 1989-11-21 1995-01-25 シェリング・コーポレーション カルボキシアルキルカルボニルアミノ酸エンドペプチダーゼ阻害剤
US5407960A (en) * 1989-12-22 1995-04-18 Schering Corporation Mercaptocycloacyl aminoacid endopeptidase inhibitors
US5075302A (en) * 1990-03-09 1991-12-24 Schering Corporation Mercaptoacyl aminolactam endopeptidase inhibitors
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DE19741873A1 (de) * 1997-09-23 1999-03-25 Hoechst Marion Roussel De Gmbh Neue 5-Ring-Heterocyclen, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate
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Also Published As

Publication number Publication date
IL64111A (en) 1984-10-31
DK154978B (da) 1989-01-16
ES8401027A1 (es) 1983-12-01
DD201887A5 (de) 1983-08-17
HU185151B (en) 1984-12-28
NO813615L (no) 1982-04-28
ES506571A0 (es) 1983-02-01
KR890000662B1 (ko) 1989-03-22
NZ198750A (en) 1984-05-31
IL64111A0 (da) 1982-01-31
US4374847A (en) 1983-02-22
NO156979C (no) 1987-12-30
NO156979B (no) 1987-09-21
EP0050850A1 (de) 1982-05-05
DE3176125D1 (en) 1987-05-27
ES8303334A1 (es) 1983-02-01
CY1380A (en) 1987-08-07
FI813349L (fi) 1982-04-28
ES516561A0 (es) 1983-12-01
GB2085880A (en) 1982-05-06
ATE26705T1 (de) 1987-05-15
CA1172257A (en) 1984-08-07
PT73879A (de) 1981-11-01
KR830007551A (ko) 1983-10-21
GB2085880B (en) 1984-05-31
MY8700568A (en) 1987-12-31
PT73879B (de) 1983-10-25
IE51688B1 (en) 1987-02-04
HK84687A (en) 1987-11-20
EP0050850B1 (de) 1987-04-22
DK470481A (da) 1982-04-28
GR74690B (da) 1984-07-03
AU546726B2 (en) 1985-09-19
AU7682381A (en) 1982-05-06

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