FI813038L - Derivater av kefalosporin foerfarande av framstaellning av dessa och sammansaettningar innehaollande dessa - Google Patents
Derivater av kefalosporin foerfarande av framstaellning av dessa och sammansaettningar innehaollande dessaInfo
- Publication number
- FI813038L FI813038L FI813038A FI813038A FI813038L FI 813038 L FI813038 L FI 813038L FI 813038 A FI813038 A FI 813038A FI 813038 A FI813038 A FI 813038A FI 813038 L FI813038 L FI 813038L
- Authority
- FI
- Finland
- Prior art keywords
- dessa
- kefalosporin
- framstaellning
- foerfarande
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55136449A JPS5759894A (en) | 1980-09-30 | 1980-09-30 | Cephalosporin for oral administration |
JP13644980 | 1980-09-30 | ||
JP5523181A JPS57169489A (en) | 1981-04-13 | 1981-04-13 | Cephalosporin derivative and its preparation |
JP5523181 | 1981-04-13 | ||
JP8911681 | 1981-06-10 | ||
JP8911681A JPS57206687A (en) | 1981-06-10 | 1981-06-10 | Cephalosporin derivative and its preparation |
Publications (3)
Publication Number | Publication Date |
---|---|
FI813038L true FI813038L (fi) | 1982-03-31 |
FI73440B FI73440B (fi) | 1987-06-30 |
FI73440C FI73440C (fi) | 1987-10-09 |
Family
ID=27295533
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI813038A FI73440C (fi) | 1980-09-30 | 1981-09-30 | Foerfarande foer framstaellning av som laekemedel anvaendbara alkyl-(eller alkoxi-)karbonyloxialkyl-7-/2- (aminotiazol-4-yl)-2-metoxi-(eller etoxi-)iminoacetamido/- 3-metoxi-metyl-3-cefem-4-karboxylat. |
Country Status (11)
Country | Link |
---|---|
US (2) | US4486425A (fi) |
EP (1) | EP0049118B1 (fi) |
KR (1) | KR870000848B1 (fi) |
AU (1) | AU547984B2 (fi) |
CA (1) | CA1171404A (fi) |
DE (1) | DE3174472D1 (fi) |
ES (4) | ES505923A0 (fi) |
FI (1) | FI73440C (fi) |
IE (1) | IE53177B1 (fi) |
NL (1) | NL930098I2 (fi) |
PH (1) | PH18740A (fi) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6458772B1 (en) * | 1909-10-07 | 2002-10-01 | Medivir Ab | Prodrugs |
US5223496A (en) * | 1987-11-10 | 1993-06-29 | The Upjohn Company | Cephalosporin antibiotics |
JPH01230547A (ja) * | 1988-01-14 | 1989-09-14 | Takeda Chem Ind Ltd | 3−オキソ酪酸第三ブチルの製造法及びその用途 |
DE3804841A1 (de) * | 1988-02-17 | 1989-08-31 | Hoechst Ag | Cephalosporinderivate und verfahren zu ihrer herstellung |
GB8809534D0 (en) * | 1988-04-22 | 1988-05-25 | Beecham Group Plc | Novel compounds |
DE3901405A1 (de) * | 1989-01-19 | 1990-07-26 | Hoechst Ag | Cephalosporinderivate und verfahren zu ihrer herstellung |
DE3919259A1 (de) * | 1989-06-13 | 1990-12-20 | Hoechst Ag | Kristalline cephem-saeureadditionssalze und verfahren zu ihrer herstellung |
YU48484B (sh) * | 1991-05-24 | 1998-09-18 | Hoechst Aktiengesellschaft | Kristalne kiselinske adicione soli diastereomerno čistih 1-(2,2-dimetilpropioniloksi)-etilestara 3-cefem-4-karbonske kiseline |
EP0531875B1 (de) * | 1991-09-07 | 2004-03-24 | Aventis Pharma Deutschland GmbH | Diastereomer des 3-Cephem-4-carbonsäure-1-(-isopropoxycarbonyloxy)ethylesters und Verfahren zu dessen Herstellung |
TW212181B (fi) * | 1992-02-14 | 1993-09-01 | Hoechst Ag | |
ES2117066T3 (es) * | 1992-05-21 | 1998-08-01 | Hoechst Ag | Procedimiento para la disociacion de esteres profarmacos de cefalosporina para dar acido 7-amino-3-metoximetil-cef-3-em-4-carboxilico. |
LT3870B (en) | 1993-11-30 | 1996-04-25 | Hoechst Ag | Diastereomers of 3-cefem-4-carboxylic acid 1-(isopropoxy-carbonyloxy)ethyl ester, process for preparingthereof, antibacteric preparations based on same and process for preparation thereof |
US5929086A (en) | 1996-05-10 | 1999-07-27 | Pharmacia & Upjohn Company | Topical administration of antimicrobial agents for the treatment of systemic bacterial diseases |
AT413383B (de) | 1998-01-09 | 2006-02-15 | Sandoz Ag | Verfahren zur isolierung eines diastereoisomerengemisches von cefpodoxim proxetil |
AT408226B (de) | 1999-05-05 | 2001-09-25 | Biochemie Gmbh | Kristalliner 7-(2-(2-formylaminothiazol-4-yl)-2 |
IN191496B (fi) | 1999-07-30 | 2003-12-06 | Ranbaxy Lab Ltd | |
KR100342944B1 (ko) * | 1999-11-08 | 2002-07-02 | 민경윤 | 고순도 세프포독심 프록세틸의 제조방법 |
BR0207640A (pt) * | 2001-02-27 | 2004-07-27 | Ranbaxy Lab Ltd | Composição farmacêutica oral de cefpodoxima proxetil |
EP1373276A4 (en) * | 2001-02-27 | 2005-03-02 | Ranbaxy Lab Ltd | PROCESS FOR THE PRODUCTION OF CEFPODOXIM PROXETIL |
EP1490090A4 (en) | 2002-02-22 | 2006-09-20 | New River Pharmaceuticals Inc | SYSTEMS FOR DELIVERING ACTIVE AGENTS AND METHODS FOR PROTECTING AND DELIVERING ACTIVE AGENTS |
AU2003282267A1 (en) * | 2002-11-22 | 2004-06-18 | Orchid Chemicals And Pharmaceuticals Ltd | An improved process for the preparation of cefpodoxime proxetil |
ATE375355T1 (de) * | 2002-12-20 | 2007-10-15 | Lupin Ltd | Verfahren zur herstellung von cefpodoxim-proxetil |
GB0301938D0 (en) * | 2003-01-28 | 2003-02-26 | Biochemie Gmbh | Organic compounds |
US20040242863A1 (en) * | 2003-05-27 | 2004-12-02 | Carenini Alessandro Riccardo | Preparation of cefalosporins intermediates and conversion of said intermediates into active compound precursors |
WO2010097675A1 (en) | 2009-02-27 | 2010-09-02 | Dhanuka Laboratories Ltd. | An improved preparation process for cefpodoxime proxetil |
TR201002878A2 (tr) | 2010-04-13 | 2011-10-21 | Bi̇lgi̇ç Mahmut | Sefpodoksim proksetil içeren farmasötik bileşimler. |
WO2011152808A1 (en) | 2010-06-03 | 2011-12-08 | Mahmut Bilgic | Formulation comprising cefpodoxime proxetil and clavulanic acid |
WO2011152805A2 (en) | 2010-06-03 | 2011-12-08 | Mahmut Bilgic | Pharmaceutical composition comprising cefpodoxime proxetil and clavulanic acid |
TR201007107A1 (tr) | 2010-08-25 | 2012-03-21 | Bi̇lgi̇ç Mahmut | Tat düzenleyici ajan içeren sefpodoksim proksetil formülasyonları. |
TR201007106A1 (tr) | 2010-08-25 | 2012-03-21 | Bi̇lgi̇ç Mahmut | Sefpodoksim proksetil formülasyonları. |
TR201009168A2 (tr) | 2010-11-05 | 2012-05-21 | Bi̇lgi̇ç Mahmut | Suda dağılan sefpodoksim proksetil formülasyonları. |
EP2520578A1 (en) | 2011-05-06 | 2012-11-07 | Lupin Limited | Process for purification of cephalosporins |
EP2758407A1 (en) | 2011-09-20 | 2014-07-30 | Dhanuka Laboratories Ltd. | An improved process for cefpodoxime acid |
WO2013151517A1 (en) | 2012-04-04 | 2013-10-10 | Mahmut Bilgic | Tablet formulations comprising cefpodoxime proxetil and clavulanic acid |
WO2014123500A1 (en) | 2013-02-11 | 2014-08-14 | Bilgiç Mahmut | Pharmaceutical formulations comprising cefpodoxime proxetil and clavulanic acid |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4024137A (en) * | 1971-05-14 | 1977-05-17 | Glaxo Laboratories Limited | 7β-[2-Etherified oximino-2-(phenyl- or naphthylacetamido)] cephalosporins |
GB1425933A (en) * | 1972-03-13 | 1976-02-25 | Astra Laekemedel Ab | Cephalosporins |
JPS5119765A (en) * | 1974-08-09 | 1976-02-17 | Takeda Chemical Industries Ltd | Aminochiazoorujudotaino seizoho |
DK154939C (da) * | 1974-12-19 | 1989-06-12 | Takeda Chemical Industries Ltd | Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf |
GR63088B (en) * | 1976-04-14 | 1979-08-09 | Takeda Chemical Industries Ltd | Preparation process of novel cephalosporins |
JPS53103493A (en) * | 1977-02-18 | 1978-09-08 | Takeda Chem Ind Ltd | Cephalosporin derivatives and process for their preparation |
DE2714880A1 (de) | 1977-04-02 | 1978-10-26 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
US4409215A (en) * | 1979-11-19 | 1983-10-11 | Fujisawa Pharmaceutical Co., Ltd. | 7-Acylamino-3-substituted cephalosporanic acid derivatives and processes for the preparation thereof |
FR2476087A1 (fr) * | 1980-02-18 | 1981-08-21 | Roussel Uclaf | Nouvelles oximes derivees de l'acide 3-alkyloxy ou 3-alkyl-thiomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
-
1981
- 1981-09-23 US US06/304,988 patent/US4486425A/en not_active Expired - Lifetime
- 1981-09-24 DE DE8181304415T patent/DE3174472D1/de not_active Expired
- 1981-09-24 EP EP81304415A patent/EP0049118B1/en not_active Expired
- 1981-09-29 PH PH26288A patent/PH18740A/en unknown
- 1981-09-30 AU AU75781/81A patent/AU547984B2/en not_active Expired
- 1981-09-30 IE IE2273/81A patent/IE53177B1/en active Protection Beyond IP Right Term
- 1981-09-30 ES ES505923A patent/ES505923A0/es active Granted
- 1981-09-30 CA CA000387048A patent/CA1171404A/en not_active Expired
- 1981-09-30 FI FI813038A patent/FI73440C/fi not_active IP Right Cessation
- 1981-09-30 KR KR1019810003696A patent/KR870000848B1/ko active
-
1982
- 1982-08-13 ES ES514993A patent/ES8306158A1/es not_active Expired
- 1982-08-13 ES ES514994A patent/ES514994A0/es active Granted
- 1982-08-13 ES ES514995A patent/ES8306759A1/es not_active Expired
-
1986
- 1986-06-10 US US06/873,114 patent/US4716158A/en not_active Expired - Lifetime
-
1993
- 1993-06-25 NL NL930098C patent/NL930098I2/nl unknown
Also Published As
Publication number | Publication date |
---|---|
ES514993A0 (es) | 1983-05-01 |
CA1171404A (en) | 1984-07-24 |
DE3174472D1 (en) | 1986-05-28 |
US4486425A (en) | 1984-12-04 |
EP0049118A3 (en) | 1983-01-19 |
EP0049118A2 (en) | 1982-04-07 |
ES514995A0 (es) | 1983-06-01 |
KR870000848B1 (ko) | 1987-04-25 |
NL930098I1 (nl) | 1993-10-01 |
AU547984B2 (en) | 1985-11-14 |
ES8306759A1 (es) | 1983-06-01 |
FI73440C (fi) | 1987-10-09 |
ES8302002A1 (es) | 1982-12-16 |
AU7578181A (en) | 1982-04-08 |
PH18740A (en) | 1985-09-16 |
ES8306159A1 (es) | 1983-05-01 |
US4716158A (en) | 1987-12-29 |
NL930098I2 (nl) | 1995-02-01 |
KR830007685A (ko) | 1983-11-04 |
ES8306158A1 (es) | 1983-05-01 |
FI73440B (fi) | 1987-06-30 |
EP0049118B1 (en) | 1986-04-23 |
ES514994A0 (es) | 1983-05-01 |
ES505923A0 (es) | 1982-12-16 |
IE812273L (en) | 1982-03-30 |
IE53177B1 (en) | 1988-08-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ND | Supplementary protection certificate (spc) granted | ||
SPCG | Supplementary protection certificate granted |
Spc suppl protection certif: L55 Extension date: 20050802 |
|
MA | Patent expired |
Owner name: SANKYO COMPANY LIMITED |