FI793039A - Oktahydro-1h-benso(4,5)-furo(3,2-e)-isokinoliner med analgetiska och narkotikaantagonistiska egenskaper - Google Patents

Oktahydro-1h-benso(4,5)-furo(3,2-e)-isokinoliner med analgetiska och narkotikaantagonistiska egenskaper

Info

Publication number
FI793039A
FI793039A FI793039A FI793039A FI793039A FI 793039 A FI793039 A FI 793039A FI 793039 A FI793039 A FI 793039A FI 793039 A FI793039 A FI 793039A FI 793039 A FI793039 A FI 793039A
Authority
FI
Finland
Prior art keywords
isokinoliner
tagonistic
egenskaper
analgetic
furo
Prior art date
Application number
FI793039A
Other languages
English (en)
Other versions
FI69076B (fi
FI69076C (fi
Inventor
Engelbert Ciganek
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/054,447 external-priority patent/US4243668A/en
Application filed by Du Pont filed Critical Du Pont
Publication of FI793039A publication Critical patent/FI793039A/fi
Publication of FI69076B publication Critical patent/FI69076B/fi
Application granted granted Critical
Publication of FI69076C publication Critical patent/FI69076C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
FI793039A 1978-10-02 1979-10-01 Foerfarande foer framstaellning av farmaceutiskt anvaendbara oktahydro-1h-benso(4,5)furo(3,2-e)isokinolinderivat samt av farmaceutiskt godtagbara syraadditionssalter av dessa FI69076C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US94803878A 1978-10-02 1978-10-02
US94803878 1978-10-02
US5444779 1979-07-09
US06/054,447 US4243668A (en) 1979-07-09 1979-07-09 Octahydro-1H-benzo[4,5]furo[3,2-e]-isoquinoline analgesic and narcotic antagonistic compounds

Publications (3)

Publication Number Publication Date
FI793039A true FI793039A (fi) 1980-04-03
FI69076B FI69076B (fi) 1985-08-30
FI69076C FI69076C (fi) 1985-12-10

Family

ID=26733043

Family Applications (1)

Application Number Title Priority Date Filing Date
FI793039A FI69076C (fi) 1978-10-02 1979-10-01 Foerfarande foer framstaellning av farmaceutiskt anvaendbara oktahydro-1h-benso(4,5)furo(3,2-e)isokinolinderivat samt av farmaceutiskt godtagbara syraadditionssalter av dessa

Country Status (20)

Country Link
US (1) US4260761A (fi)
EP (1) EP0009780B1 (fi)
AR (1) AR227009A1 (fi)
AT (1) ATE722T1 (fi)
AU (1) AU526150B2 (fi)
CA (2) CA1150263A (fi)
DE (1) DE2962208D1 (fi)
DK (1) DK337879A (fi)
ES (1) ES484664A1 (fi)
FI (1) FI69076C (fi)
GR (1) GR73596B (fi)
HU (1) HU180224B (fi)
IE (1) IE48556B1 (fi)
IL (3) IL58356A (fi)
NO (1) NO151705C (fi)
NZ (1) NZ191715A (fi)
PH (1) PH14636A (fi)
PT (1) PT70262A (fi)
SU (1) SU1060114A3 (fi)
YU (1) YU239679A (fi)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4477456A (en) * 1981-07-02 1984-10-16 E. I. Du Pont De Nemours And Company Octahydro-4A,7-ethano- and -etheno-benzofuro[3,2-e]isoquinoline derivatives having analgesic, narcotic antagonist and anorexigenic properties
RU2475489C1 (ru) * 2011-10-07 2013-02-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Чувашский государственный университет имени И.Н. Ульянова" Способ получения 8-амино-1-имино-6-морфолин-4-ил-2-окса-7-азаспиро[4,4]нона-3,6,8-триен-9-карбонитрилов

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3979394A (en) * 1970-12-11 1976-09-07 Agfa-Gevaert N.V. Duplo quinoline compounds
GB1379387A (en) * 1970-12-11 1975-01-02 Agfa Gevaert Photoconductive recording materials
GB1400993A (en) * 1971-11-10 1975-07-16 Agfa Gevaert Electrophotographic material
BE795696A (nl) * 1972-02-28 1973-08-21 Agfa Gevaert Nv Voor warmte gevoelige materialen

Also Published As

Publication number Publication date
ATE722T1 (de) 1982-03-15
AU5130479A (en) 1980-04-17
AU526150B2 (en) 1982-12-16
PT70262A (en) 1979-11-01
GR73596B (fi) 1984-03-26
IE48556B1 (en) 1985-03-06
SU1060114A3 (ru) 1983-12-07
NO151705B (no) 1985-02-11
HU180224B (en) 1983-02-28
EP0009780A2 (en) 1980-04-16
FI69076B (fi) 1985-08-30
US4260761A (en) 1981-04-07
IL69127A (en) 1984-05-31
ES484664A1 (es) 1980-09-01
IL58356A0 (en) 1979-12-30
NO793147L (no) 1980-04-08
EP0009780B1 (en) 1982-02-24
DE2962208D1 (en) 1982-03-25
YU239679A (en) 1983-04-30
IE791858L (en) 1980-04-02
CA1150263A (en) 1983-07-19
DK337879A (da) 1980-04-03
CA1157861A (en) 1983-11-29
IL69127A0 (en) 1983-10-31
PH14636A (en) 1981-10-12
NZ191715A (en) 1984-05-31
EP0009780A3 (en) 1980-06-25
NO151705C (no) 1985-06-05
AR227009A1 (es) 1982-09-15
FI69076C (fi) 1985-12-10
IL58356A (en) 1984-05-31

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: E.I. DU PONT DE NEMOURS AND COMPANY