FI70413C - Foerfarande foer framstaellning av nya som bronchodilatorer anaendbara 6-aminosubstituerade 7,8,9,10-tetrahydro(1,2,4)t rizolo/3,4 a/ ftalaziner samt salter daerav - Google Patents

Foerfarande foer framstaellning av nya som bronchodilatorer anaendbara 6-aminosubstituerade 7,8,9,10-tetrahydro(1,2,4)t rizolo/3,4 a/ ftalaziner samt salter daerav Download PDF

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Publication number
FI70413C
FI70413C FI803355A FI803355A FI70413C FI 70413 C FI70413 C FI 70413C FI 803355 A FI803355 A FI 803355A FI 803355 A FI803355 A FI 803355A FI 70413 C FI70413 C FI 70413C
Authority
FI
Finland
Prior art keywords
formula
tetrahydro
amine
methyl
triazolo
Prior art date
Application number
FI803355A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI70413B (fi
FI803355L (fi
Inventor
Norton Paul Peet
Shyam Sunder
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Publication of FI803355L publication Critical patent/FI803355L/fi
Publication of FI70413B publication Critical patent/FI70413B/fi
Application granted granted Critical
Publication of FI70413C publication Critical patent/FI70413C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI803355A 1979-10-29 1980-10-27 Foerfarande foer framstaellning av nya som bronchodilatorer anaendbara 6-aminosubstituerade 7,8,9,10-tetrahydro(1,2,4)t rizolo/3,4 a/ ftalaziner samt salter daerav FI70413C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8907179A 1979-10-29 1979-10-29
US8907179 1979-10-29

Publications (3)

Publication Number Publication Date
FI803355L FI803355L (fi) 1981-04-30
FI70413B FI70413B (fi) 1986-03-27
FI70413C true FI70413C (fi) 1986-09-19

Family

ID=22215530

Family Applications (1)

Application Number Title Priority Date Filing Date
FI803355A FI70413C (fi) 1979-10-29 1980-10-27 Foerfarande foer framstaellning av nya som bronchodilatorer anaendbara 6-aminosubstituerade 7,8,9,10-tetrahydro(1,2,4)t rizolo/3,4 a/ ftalaziner samt salter daerav

Country Status (18)

Country Link
EP (1) EP0029130B1 (zh)
JP (1) JPS5679690A (zh)
KR (1) KR850001701B1 (zh)
AR (2) AR227651A1 (zh)
AT (1) ATE16808T1 (zh)
AU (1) AU536351B2 (zh)
CA (1) CA1144544A (zh)
DE (1) DE3071278D1 (zh)
DK (1) DK158353C (zh)
ES (2) ES8202555A1 (zh)
FI (1) FI70413C (zh)
GB (1) GB2061275B (zh)
GR (1) GR70309B (zh)
IL (1) IL61316A (zh)
NO (1) NO156011C (zh)
NZ (1) NZ195355A (zh)
PT (1) PT71952B (zh)
ZA (1) ZA806523B (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH21834A (en) * 1982-01-18 1988-03-17 Lepetit Spa New 6-substituted-s-triazolo(3,4-a)phthalazine derivatives
US4485106A (en) * 1982-07-12 1984-11-27 The Dow Chemical Company Substituted tetrahydrotetrazolo[5,1-a]phthalazines
US4487930A (en) * 1982-09-07 1984-12-11 The Dow Chemical Company 6-[(Cyclic amino)alkylamino]-tetrahydrotriazolo[3,4-a]phthalazines
IT1194310B (it) * 1983-07-12 1988-09-14 Lepetit Spa Derivati triazolo (3,4-a) ftalazinici 3,6-disostituiti
US4578464A (en) * 1983-11-22 1986-03-25 Merrell Dow Pharmaceuticals Inc. 6-Hydroxyalkylamino-8-methyl-1,2,4-triazolo-[4,3-b]pyridazine and related compounds
US5011835A (en) * 1990-02-07 1991-04-30 Merrell Dow Pharmaceuticals Inc. Substituted triazolopyridazines, pharmaceutical compositions and use
CN102791715B (zh) 2009-12-31 2016-04-27 卡洛斯三世国家癌症研究中心基金会 用作激酶抑制剂的三环化合物
WO2012098387A1 (en) 2011-01-18 2012-07-26 Centro Nacional De Investigaciones Oncológicas (Cnio) 6, 7-ring-fused triazolo [4, 3 - b] pyridazine derivatives as pim inhibitors
WO2013005057A1 (en) 2011-07-07 2013-01-10 Centro Nacional De Investigaciones Oncológicas (Cnio) New compounds
WO2013005041A1 (en) 2011-07-07 2013-01-10 Centro Nacional De Investigaciones Oncológicas (Cnio) Tricyclic heterocyclic compounds as kinase inhibitors
WO2013004984A1 (en) 2011-07-07 2013-01-10 Centro Nacional De Investigaciones Oncologicas (Cnio) Tricyclic compounds for use as kinase inhibitors
CN103694244B (zh) * 2014-01-09 2016-03-30 郑州大学 3,6位取代-1,2,4-三氮唑并[3,4-a]酞嗪类化合物及其制备和用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3708484A (en) * 1970-10-16 1973-01-02 Sandoz Ag Amino and substituted amino-s-triazolo-(4,3-b)-pyridazines
US3915968A (en) * 1973-09-21 1975-10-28 Lepetit Spa Triazolopyridazines
DE2418435A1 (de) * 1974-04-17 1975-10-30 Boehringer Mannheim Gmbh Nitroimidazolyl-triazolo-pyridazine und verfahren zu ihrer herstellung
US4136182A (en) * 1976-05-26 1979-01-23 The Dow Chemical Company Triazolopyridazines used to alleviate bronchial spasms
CA1080712A (en) * 1976-09-22 1980-07-01 Jay D. Albright Hypotensive agents

Also Published As

Publication number Publication date
ZA806523B (en) 1982-05-26
ES496354A0 (es) 1982-02-01
FI70413B (fi) 1986-03-27
DE3071278D1 (en) 1986-01-16
ATE16808T1 (de) 1985-12-15
EP0029130A1 (en) 1981-05-27
NO156011C (no) 1987-07-08
NZ195355A (en) 1984-09-28
ES506946A0 (es) 1982-09-01
NO156011B (no) 1987-03-30
ES8207178A1 (es) 1982-09-01
KR850001701B1 (ko) 1985-11-26
EP0029130B1 (en) 1985-12-04
PT71952A (en) 1980-11-01
GB2061275B (en) 1983-08-10
AU6356180A (en) 1981-05-07
ES8202555A1 (es) 1982-02-01
IL61316A0 (en) 1980-12-31
JPH0248558B2 (zh) 1990-10-25
AR227087A1 (es) 1982-09-15
DK457480A (da) 1981-04-30
DK158353B (da) 1990-05-07
NO803218L (no) 1981-04-30
DK158353C (da) 1990-10-01
CA1144544A (en) 1983-04-12
GR70309B (zh) 1982-09-08
IL61316A (en) 1984-03-30
PT71952B (en) 1982-03-31
AR227651A1 (es) 1982-11-30
FI803355L (fi) 1981-04-30
KR830004301A (ko) 1983-07-09
AU536351B2 (en) 1984-05-03
GB2061275A (en) 1981-05-13
JPS5679690A (en) 1981-06-30

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Owner name: THE DOW CHEMICAL COMPANY