FI68621C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 5-cyanoprostacyklinderivat - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 5-cyanoprostacyklinderivat Download PDF

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Publication number
FI68621C
FI68621C FI783590A FI783590A FI68621C FI 68621 C FI68621 C FI 68621C FI 783590 A FI783590 A FI 783590A FI 783590 A FI783590 A FI 783590A FI 68621 C FI68621 C FI 68621C
Authority
FI
Finland
Prior art keywords
group
carbon atoms
ether
solution
mixture
Prior art date
Application number
FI783590A
Other languages
English (en)
Finnish (fi)
Other versions
FI783590A (fi
FI68621B (fi
Inventor
Helmut Vorbrueggen
Werner Skuballa
Bernd Raduechel
Wolfgang Losert
Olaf Loge
Bernd Mueller
Gerda Mannesmann
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of FI783590A publication Critical patent/FI783590A/fi
Application granted granted Critical
Publication of FI68621B publication Critical patent/FI68621B/fi
Publication of FI68621C publication Critical patent/FI68621C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
FI783590A 1977-11-25 1978-11-23 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 5-cyanoprostacyklinderivat FI68621C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2753244 1977-11-25
DE19772753244 DE2753244A1 (de) 1977-11-25 1977-11-25 Neue prostacyclinderivate und verfahren zu ihrer herstellung

Publications (3)

Publication Number Publication Date
FI783590A FI783590A (fi) 1979-05-26
FI68621B FI68621B (fi) 1985-06-28
FI68621C true FI68621C (fi) 1985-10-10

Family

ID=6024901

Family Applications (1)

Application Number Title Priority Date Filing Date
FI783590A FI68621C (fi) 1977-11-25 1978-11-23 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 5-cyanoprostacyklinderivat

Country Status (23)

Country Link
US (1) US4219479A (cs)
EP (1) EP0002234B1 (cs)
JP (1) JPS5481257A (cs)
AT (1) AT371455B (cs)
AU (1) AU523420B2 (cs)
CA (1) CA1180701A (cs)
CS (1) CS209909B2 (cs)
DD (1) DD140042A5 (cs)
DE (2) DE2753244A1 (cs)
DK (1) DK153482C (cs)
ES (1) ES475377A1 (cs)
FI (1) FI68621C (cs)
GR (1) GR72772B (cs)
HU (1) HU181518B (cs)
IE (1) IE47497B1 (cs)
IL (1) IL56017A (cs)
IT (1) IT1160264B (cs)
NO (1) NO148642C (cs)
NZ (1) NZ188976A (cs)
PH (1) PH20276A (cs)
SU (1) SU923365A3 (cs)
YU (1) YU271078A (cs)
ZA (1) ZA786622B (cs)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4178367A (en) * 1977-02-21 1979-12-11 Ono Pharmaceutical Co. Ltd. Prostaglandin I2 analogues
DE2902809A1 (de) * 1979-01-25 1980-08-07 Hoechst Ag Neue analoga von prostacyclin
DE3004795A1 (de) * 1980-02-07 1981-08-13 Schering Ag Berlin Und Bergkamen, 1000 Berlin Neue prostacyclinderivate, ihre herstellung und anwendung
DE3041601A1 (de) * 1980-10-31 1982-06-16 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue prostacyclinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3041602A1 (de) * 1980-10-31 1982-06-16 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue 5-cyan-prostacyclinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3322893A1 (de) * 1983-06-23 1985-01-03 Schering AG, 1000 Berlin und 4709 Bergkamen Neue prostacyclinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3448256C2 (en) * 1984-07-25 1988-08-18 Schering Ag, 1000 Berlin Und 4709 Bergkamen, De Cytoprotective action of prostacyclin derivatives on the pancreas
DE3427797A1 (de) * 1984-07-25 1986-02-06 Schering AG, 1000 Berlin und 4709 Bergkamen Zytoprotektive wirkung von prostacyclin-derivaten an leber, bauchspeicheldruese und niere
DE3740838A1 (de) * 1987-11-27 1989-06-08 Schering Ag Cyclodextrinclathrate von 5-cyano-prostacyclinderivaten und ihre verwendung als arzneimittel
JP2009543826A (ja) * 2006-07-18 2009-12-10 バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト 自己免疫疾患治療剤としての５−シアノ−プロスタサイクリン誘導体
EP2269611B1 (en) * 2006-11-16 2016-03-23 Gemmus Pharma Inc. EP2 and EP4 agonists as agents for the treatment of influenza A viral infection
US7776896B2 (en) * 2007-03-28 2010-08-17 Bayer Schering Pharma Aktiengesellschaft 5-cyano-prostacyclin derivatives as agents for the treatment of influenza a viral infection
EP1988087A1 (en) * 2007-03-28 2008-11-05 Bayer Schering Pharma Aktiengesellschaft Novel 5-cyano-prostacyclin derivatives and their use as agents for the treatment of autoimmune diseases
US20080242713A1 (en) * 2007-03-28 2008-10-02 Bayer Schering Pharma Aktiengesellschaft Novel 5-cyano-prostacyclin derivatives as agents for the treatment of autoimmune diseases
EP1975163A1 (en) * 2007-03-28 2008-10-01 Bayer Schering Pharma Aktiengesellschaft Novel 5-cyano-prostacyclin derivatives and their use as agents for the treatment of influenza a viral infection
US20160184387A1 (en) 2013-08-09 2016-06-30 Dominique Charmot Compounds and methods for inhibiting phosphate transport
EP3972599A1 (en) 2019-05-21 2022-03-30 Ardelyx, Inc. Combination for lowering serum phosphate in a patient
US20210113783A1 (en) 2019-10-20 2021-04-22 Respira Technologies, Inc. Electronic devices and liquids for aerosolizing and inhaling therewith

Also Published As

Publication number Publication date
FI783590A (fi) 1979-05-26
SU923365A3 (ru) 1982-04-23
IL56017A (en) 1983-03-31
EP0002234A1 (de) 1979-06-13
HU181518B (en) 1983-10-28
ES475377A1 (es) 1979-04-01
NO148642C (no) 1983-11-16
PH20276A (en) 1986-11-14
IE47497B1 (en) 1984-04-04
ATA836478A (de) 1982-11-15
IL56017A0 (en) 1979-01-31
IE782321L (en) 1979-05-25
AU523420B2 (en) 1982-07-29
AT371455B (de) 1983-06-27
NO148642B (no) 1983-08-08
FI68621B (fi) 1985-06-28
EP0002234B1 (de) 1981-02-11
US4219479A (en) 1980-08-26
NO783964L (no) 1979-05-28
ZA786622B (en) 1979-10-31
IT1160264B (it) 1987-03-11
JPS6220989B2 (cs) 1987-05-11
JPS5481257A (en) 1979-06-28
AU4191278A (en) 1979-05-31
GR72772B (cs) 1983-12-05
CS209909B2 (en) 1981-12-31
YU271078A (en) 1983-01-21
DK153482B (da) 1988-07-18
DK153482C (da) 1988-12-27
DD140042A5 (de) 1980-02-06
DK522578A (da) 1979-05-26
NZ188976A (en) 1979-12-11
CA1180701A (en) 1985-01-08
IT7830174A0 (it) 1978-11-24
DE2753244A1 (de) 1979-06-07
DE2860486D1 (en) 1981-03-26

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Owner name: SCHERING AKTIENGESELLSCHAFT