FI67212C - Foerfarande foer framstaellning av nya saosom laekemedel anvaendbara aziridin-derivat - Google Patents

Foerfarande foer framstaellning av nya saosom laekemedel anvaendbara aziridin-derivat Download PDF

Info

Publication number
FI67212C
FI67212C FI770718A FI770718A FI67212C FI 67212 C FI67212 C FI 67212C FI 770718 A FI770718 A FI 770718A FI 770718 A FI770718 A FI 770718A FI 67212 C FI67212 C FI 67212C
Authority
FI
Finland
Prior art keywords
carbamoylaziridinyl
cyanoaziridinyl
cyanaziridine
group
aziridinyl
Prior art date
Application number
FI770718A
Other languages
English (en)
Finnish (fi)
Other versions
FI770718A (sv
FI67212B (fi
Inventor
Wolfgang Kampe
Max Thiel
Erich Fauland
Uwe Bicker
Gottfried Hebold
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19762610156 external-priority patent/DE2610156A1/de
Priority claimed from DE19762632517 external-priority patent/DE2632517A1/de
Priority claimed from DE19762656240 external-priority patent/DE2656240C2/de
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of FI770718A publication Critical patent/FI770718A/fi
Application granted granted Critical
Publication of FI67212B publication Critical patent/FI67212B/fi
Publication of FI67212C publication Critical patent/FI67212C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
FI770718A 1976-03-11 1977-03-07 Foerfarande foer framstaellning av nya saosom laekemedel anvaendbara aziridin-derivat FI67212C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE2610156 1976-03-11
DE19762610156 DE2610156A1 (de) 1976-03-11 1976-03-11 1-eckige klammer auf 2-cyanaziridinyl-(1)eckige klammer zu-1-eckige klammer auf 2-carbamoyl-aziridinyl- (1)eckige klammer zu-cyclohexan
DE2632517 1976-07-20
DE19762632517 DE2632517A1 (de) 1976-07-20 1976-07-20 2- eckige klammer auf 2-cyanaziridinyl- (1) eckige klammer zu -2- eckige klammer auf 2-carbamoyl-aziridinyl-(1) eckige klammer zu -propan und verfahren zu dessen herstellung
DE2656240 1976-12-11
DE19762656240 DE2656240C2 (de) 1976-12-11 1976-12-11 Neue Aziridin-Derivate, Verfahren zu deren Herstellung und pharmazeutische Mittel

Publications (3)

Publication Number Publication Date
FI770718A FI770718A (sv) 1977-09-12
FI67212B FI67212B (fi) 1984-10-31
FI67212C true FI67212C (fi) 1985-02-11

Family

ID=27186778

Family Applications (1)

Application Number Title Priority Date Filing Date
FI770718A FI67212C (fi) 1976-03-11 1977-03-07 Foerfarande foer framstaellning av nya saosom laekemedel anvaendbara aziridin-derivat

Country Status (28)

Country Link
US (1) US4370323A (sv)
JP (1) JPS52111563A (sv)
AR (1) AR214733A1 (sv)
AT (1) AT351043B (sv)
CA (1) CA1086321A (sv)
CH (1) CH629770A5 (sv)
DD (1) DD128615A5 (sv)
DK (1) DK154832B (sv)
EG (1) EG13513A (sv)
ES (1) ES456632A1 (sv)
FI (1) FI67212C (sv)
FR (1) FR2343739A1 (sv)
GB (1) GB1518494A (sv)
GR (1) GR73009B (sv)
HU (1) HU176646B (sv)
IE (1) IE44640B1 (sv)
IL (1) IL51602A (sv)
IT (1) IT1076885B (sv)
LU (1) LU76918A1 (sv)
NL (1) NL177916C (sv)
NO (1) NO147185C (sv)
NZ (1) NZ183528A (sv)
OA (1) OA05594A (sv)
PL (1) PL106627B1 (sv)
PT (1) PT66275B (sv)
SE (1) SE436128B (sv)
SU (1) SU673167A3 (sv)
YU (1) YU63077A (sv)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT386195B (de) * 1978-08-03 1988-07-11 Boehringer Mannheim Gmbh Verfahren zur herstellung von neuen n-substituierten aziridin-2-carbonsaeurederivaten und ihren salzen
US4925835A (en) * 1986-05-01 1990-05-15 Sloan-Kettering Institute For Cancer Research Aziridinyl putrescine containing compositions and their uses in treating prostate cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3828024A (en) * 1970-12-21 1974-08-06 Hercules Inc Poly(aziridine)s

Also Published As

Publication number Publication date
LU76918A1 (sv) 1977-07-12
JPS52111563A (en) 1977-09-19
PL106627B1 (pl) 1980-01-31
FI770718A (sv) 1977-09-12
DD128615A5 (de) 1977-11-30
DK98577A (da) 1977-09-12
AT351043B (de) 1979-07-10
IE44640B1 (en) 1982-02-10
IL51602A (en) 1980-11-30
PL196543A1 (pl) 1978-02-27
SU673167A3 (ru) 1979-07-05
GB1518494A (en) 1978-07-19
NL7702527A (nl) 1977-09-13
GR73009B (sv) 1984-01-24
US4370323A (en) 1983-01-25
YU63077A (en) 1982-06-30
AU2295477A (en) 1978-02-09
CA1086321A (en) 1980-09-23
NO147185C (no) 1983-02-16
HU176646B (en) 1981-04-28
DK154832B (da) 1988-12-27
NL177916C (nl) 1985-12-16
SE7702521L (sv) 1977-09-12
FR2343739A1 (fr) 1977-10-07
CH629770A5 (de) 1982-05-14
ES456632A1 (es) 1978-01-16
NO147185B (no) 1982-11-08
PT66275B (de) 1978-08-08
OA05594A (fr) 1981-04-30
IE44640L (en) 1977-09-11
IL51602A0 (en) 1977-05-31
ATA154277A (de) 1978-12-15
NZ183528A (en) 1978-07-28
PT66275A (de) 1977-04-01
AR214733A1 (es) 1979-07-31
FR2343739B1 (sv) 1980-04-30
NO770847L (no) 1977-09-13
EG13513A (en) 1981-12-31
IT1076885B (it) 1985-04-27
JPS6153342B2 (sv) 1986-11-17
SE436128B (sv) 1984-11-12
FI67212B (fi) 1984-10-31

Similar Documents

Publication Publication Date Title
EP0613894B1 (en) N-Heteroaryl-N&#39;-phenylurea derivatives, their production and use
JP2003012686A (ja) ピラゾール誘導体
KR20060127909A (ko) 호흡기 다핵체 바이러스 감염 치료용 다환 물질
FR2673182A1 (fr) Piperazines n,n&#39;-disubstituees, leur procede de preparation et leur application en therapeutique.
EP2496230B1 (en) Ire-1 alpha inhibitors
US5110831A (en) Vinylogous hydroxamic acids and derivatives thereof as 5-lipoxygenase inhibitors
CN113234089B (zh) 柠檬苦素类化合物、制备方法及其作为治疗棘球蚴包虫病药物的应用
FI67212C (fi) Foerfarande foer framstaellning av nya saosom laekemedel anvaendbara aziridin-derivat
US20050176813A1 (en) Novel chalcone derivatives and uses thereof
US4029808A (en) Thienyl phenyl O-(aminoalkyl)-ketone oxime and furyl phenyl O-(aminoalkyl)-ketone oxime coronary vasodilators
JPH072812A (ja) チアジアジノン
US3696116A (en) 1-(2-aminocarbonyloxyethyl)-5-nitro-imidazole derivatives having antiprotozoal activity
CS272226B2 (en) Method of new lensofuran-2 ylimidazol derivatives production
US4064244A (en) Organic compounds
JP3193789B2 (ja) チアジアジノン類
EP1590355A1 (fr) Derives d azepines tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US3963740A (en) Benzo and benzothiopyranoindazole N-oxides
US3963756A (en) Derivatives of 6-methyl-2H-pyran-2,4(3H)-dione
EP1173420A2 (en) Heterocyclic compounds having antitumor activity
NL8303965A (nl) Nieuwe etheendiamine- en guanidine-derivaten; werkwijze voor het bereiden daarvan; geneesmiddelen die ze bevatten; werkwijze voor het bereiden van dergelijke geneesmiddelen; toepassing van de verbindingen voor het bereiden van geneesmiddelen en in de geneeskunde.
JP3068175B2 (ja) イソチアゾロ〔５，４―ｂ〕ピリジン誘導体
US4732906A (en) Dioxolobenzizoxazole derivatives
US3522252A (en) Basic esters of 5-alkanoylamino-3-(5&#39;-nitrofur - 2&#39; - yl)isoxazole - 4 - carboxylic acid
JPH0892248A (ja) インドリノン誘導体
US3522251A (en) Basic esters of 5-amino-3-(5&#39;-nitrofur-2&#39;-yl)isoxazole-4-carboxylic acid

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: BOEHRINGER MANNHEIM GMBH