FI67212C - Foerfarande foer framstaellning av nya saosom laekemedel anvaendbara aziridin-derivat - Google Patents

Foerfarande foer framstaellning av nya saosom laekemedel anvaendbara aziridin-derivat Download PDF

Info

Publication number
FI67212C
FI67212C FI770718A FI770718A FI67212C FI 67212 C FI67212 C FI 67212C FI 770718 A FI770718 A FI 770718A FI 770718 A FI770718 A FI 770718A FI 67212 C FI67212 C FI 67212C
Authority
FI
Finland
Prior art keywords
carbamoylaziridinyl
cyanoaziridinyl
cyanaziridine
group
aziridinyl
Prior art date
Application number
FI770718A
Other languages
English (en)
Finnish (fi)
Other versions
FI770718A (hu
FI67212B (fi
Inventor
Wolfgang Kampe
Max Thiel
Erich Fauland
Uwe Bicker
Gottfried Hebold
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19762610156 external-priority patent/DE2610156A1/de
Priority claimed from DE19762632517 external-priority patent/DE2632517A1/de
Priority claimed from DE19762656240 external-priority patent/DE2656240C2/de
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of FI770718A publication Critical patent/FI770718A/fi
Publication of FI67212B publication Critical patent/FI67212B/fi
Application granted granted Critical
Publication of FI67212C publication Critical patent/FI67212C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D203/00Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
FI770718A 1976-03-11 1977-03-07 Foerfarande foer framstaellning av nya saosom laekemedel anvaendbara aziridin-derivat FI67212C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE2610156 1976-03-11
DE19762610156 DE2610156A1 (de) 1976-03-11 1976-03-11 1-eckige klammer auf 2-cyanaziridinyl-(1)eckige klammer zu-1-eckige klammer auf 2-carbamoyl-aziridinyl- (1)eckige klammer zu-cyclohexan
DE2632517 1976-07-20
DE19762632517 DE2632517A1 (de) 1976-07-20 1976-07-20 2- eckige klammer auf 2-cyanaziridinyl- (1) eckige klammer zu -2- eckige klammer auf 2-carbamoyl-aziridinyl-(1) eckige klammer zu -propan und verfahren zu dessen herstellung
DE19762656240 DE2656240C2 (de) 1976-12-11 1976-12-11 Neue Aziridin-Derivate, Verfahren zu deren Herstellung und pharmazeutische Mittel
DE2656240 1976-12-11

Publications (3)

Publication Number Publication Date
FI770718A FI770718A (hu) 1977-09-12
FI67212B FI67212B (fi) 1984-10-31
FI67212C true FI67212C (fi) 1985-02-11

Family

ID=27186778

Family Applications (1)

Application Number Title Priority Date Filing Date
FI770718A FI67212C (fi) 1976-03-11 1977-03-07 Foerfarande foer framstaellning av nya saosom laekemedel anvaendbara aziridin-derivat

Country Status (28)

Country Link
US (1) US4370323A (hu)
JP (1) JPS52111563A (hu)
AR (1) AR214733A1 (hu)
AT (1) AT351043B (hu)
CA (1) CA1086321A (hu)
CH (1) CH629770A5 (hu)
DD (1) DD128615A5 (hu)
DK (1) DK154832B (hu)
EG (1) EG13513A (hu)
ES (1) ES456632A1 (hu)
FI (1) FI67212C (hu)
FR (1) FR2343739A1 (hu)
GB (1) GB1518494A (hu)
GR (1) GR73009B (hu)
HU (1) HU176646B (hu)
IE (1) IE44640B1 (hu)
IL (1) IL51602A (hu)
IT (1) IT1076885B (hu)
LU (1) LU76918A1 (hu)
NL (1) NL177916C (hu)
NO (1) NO147185C (hu)
NZ (1) NZ183528A (hu)
OA (1) OA05594A (hu)
PL (1) PL106627B1 (hu)
PT (1) PT66275B (hu)
SE (1) SE436128B (hu)
SU (1) SU673167A3 (hu)
YU (1) YU63077A (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT386195B (de) * 1978-08-03 1988-07-11 Boehringer Mannheim Gmbh Verfahren zur herstellung von neuen n-substituierten aziridin-2-carbonsaeurederivaten und ihren salzen
US4925835A (en) * 1986-05-01 1990-05-15 Sloan-Kettering Institute For Cancer Research Aziridinyl putrescine containing compositions and their uses in treating prostate cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3828024A (en) * 1970-12-21 1974-08-06 Hercules Inc Poly(aziridine)s

Also Published As

Publication number Publication date
GR73009B (hu) 1984-01-24
SU673167A3 (ru) 1979-07-05
FI770718A (hu) 1977-09-12
IE44640B1 (en) 1982-02-10
DD128615A5 (de) 1977-11-30
ES456632A1 (es) 1978-01-16
OA05594A (fr) 1981-04-30
HU176646B (en) 1981-04-28
EG13513A (en) 1981-12-31
PL106627B1 (pl) 1980-01-31
IL51602A (en) 1980-11-30
NL7702527A (nl) 1977-09-13
NO147185C (no) 1983-02-16
FR2343739A1 (fr) 1977-10-07
NL177916C (nl) 1985-12-16
NO147185B (no) 1982-11-08
FI67212B (fi) 1984-10-31
US4370323A (en) 1983-01-25
NO770847L (no) 1977-09-13
SE436128B (sv) 1984-11-12
DK154832B (da) 1988-12-27
FR2343739B1 (hu) 1980-04-30
IT1076885B (it) 1985-04-27
PL196543A1 (pl) 1978-02-27
CA1086321A (en) 1980-09-23
CH629770A5 (de) 1982-05-14
IL51602A0 (en) 1977-05-31
SE7702521L (sv) 1977-09-12
IE44640L (en) 1977-09-11
LU76918A1 (hu) 1977-07-12
PT66275B (de) 1978-08-08
NZ183528A (en) 1978-07-28
PT66275A (de) 1977-04-01
YU63077A (en) 1982-06-30
AR214733A1 (es) 1979-07-31
ATA154277A (de) 1978-12-15
DK98577A (da) 1977-09-12
AU2295477A (en) 1978-02-09
AT351043B (de) 1979-07-10
GB1518494A (en) 1978-07-19
JPS52111563A (en) 1977-09-19
JPS6153342B2 (hu) 1986-11-17

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: BOEHRINGER MANNHEIM GMBH