FI67083C - Foerfarande foer framstaellning av terapeutiskt anvaendbart 7-2-(2-amino-4-tiazolyl)-2-metoxi-iminoacetamido/-3-(4-mety l--oxo-6-hydroxi-4,5-dihydro-1,2,4-triazin-3-yltio)metyl-3- ceem-4-karboxylsyraderivat - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbart 7-2-(2-amino-4-tiazolyl)-2-metoxi-iminoacetamido/-3-(4-mety l--oxo-6-hydroxi-4,5-dihydro-1,2,4-triazin-3-yltio)metyl-3- ceem-4-karboxylsyraderivat Download PDF

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Publication number
FI67083C
FI67083C FI783846A FI783846A FI67083C FI 67083 C FI67083 C FI 67083C FI 783846 A FI783846 A FI 783846A FI 783846 A FI783846 A FI 783846A FI 67083 C FI67083 C FI 67083C
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FI
Finland
Prior art keywords
formula
methyl
amino
group
dihydro
Prior art date
Application number
FI783846A
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English (en)
Finnish (fi)
Other versions
FI67083B (fi
FI783846A (fi
Inventor
Allen Samuel Katner
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI783846A publication Critical patent/FI783846A/fi
Application granted granted Critical
Publication of FI67083B publication Critical patent/FI67083B/fi
Publication of FI67083C publication Critical patent/FI67083C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI783846A 1977-12-20 1978-12-14 Foerfarande foer framstaellning av terapeutiskt anvaendbart 7-2-(2-amino-4-tiazolyl)-2-metoxi-iminoacetamido/-3-(4-mety l--oxo-6-hydroxi-4,5-dihydro-1,2,4-triazin-3-yltio)metyl-3- ceem-4-karboxylsyraderivat FI67083C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/862,318 US4200745A (en) 1977-12-20 1977-12-20 7[2-(2-Aminothiazol-4-yl)-2-alkoxyimino]acetamido 3[4-alkyl-5-oxo-6-hydroxy-3,4 dihydro 1,2,4-triazin 3-yl]thio methyl cephalosporins
US86231877 1977-12-20

Publications (3)

Publication Number Publication Date
FI783846A FI783846A (fi) 1979-06-21
FI67083B FI67083B (fi) 1984-09-28
FI67083C true FI67083C (fi) 1985-01-10

Family

ID=25338200

Family Applications (1)

Application Number Title Priority Date Filing Date
FI783846A FI67083C (fi) 1977-12-20 1978-12-14 Foerfarande foer framstaellning av terapeutiskt anvaendbart 7-2-(2-amino-4-tiazolyl)-2-metoxi-iminoacetamido/-3-(4-mety l--oxo-6-hydroxi-4,5-dihydro-1,2,4-triazin-3-yltio)metyl-3- ceem-4-karboxylsyraderivat

Country Status (33)

Country Link
US (1) US4200745A (cs)
EP (1) EP0002605B1 (cs)
JP (1) JPS5490194A (cs)
AR (1) AR220733A1 (cs)
AT (1) AT364189B (cs)
AU (1) AU518484B2 (cs)
BE (1) BE872616A (cs)
CA (1) CA1140112A (cs)
CH (1) CH635846A5 (cs)
CS (1) CS204957B2 (cs)
DD (1) DD139857A5 (cs)
DE (1) DE2861493D1 (cs)
DK (1) DK540278A (cs)
EG (1) EG13666A (cs)
ES (1) ES476154A1 (cs)
FI (1) FI67083C (cs)
FR (1) FR2412553A1 (cs)
GB (1) GB2010256B (cs)
GR (1) GR72240B (cs)
HU (1) HU181875B (cs)
IE (1) IE47696B1 (cs)
IL (1) IL56166A0 (cs)
IT (1) IT1112300B (cs)
LU (1) LU80669A1 (cs)
MX (1) MX5586E (cs)
NZ (1) NZ189121A (cs)
PH (1) PH15368A (cs)
PL (1) PL123368B1 (cs)
PT (1) PT68888A (cs)
RO (1) RO75804A (cs)
SU (1) SU793403A3 (cs)
YU (1) YU300278A (cs)
ZA (1) ZA787110B (cs)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5760345B2 (cs) * 1974-12-19 1982-12-18 Takeda Chemical Industries Ltd
CH641468A5 (de) * 1978-05-30 1984-02-29 Hoffmann La Roche Cephemderivate.
MC1259A1 (fr) * 1978-05-30 1980-01-14 Hoffmann La Roche Derives acyles
ZA806977B (en) * 1979-11-19 1981-10-28 Fujisawa Pharmaceutical Co 7-acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
FI67385C (fi) * 1979-11-21 1985-03-11 Hoffmann La Roche Foerfarande foer framstaellning av (6r 7r)-7-(2-(2-amino-4-tiazolyl)-2-(z-metoxiimino)acetamido)-3-cefem-4-karboxylsyraderivat
US4349672A (en) * 1979-11-29 1982-09-14 Hoffmann-La Roche Inc. Cephalosporin derivatives
US4409387A (en) * 1979-11-29 1983-10-11 Hoffmann-La Roche Inc. Cephalosporin derivatives
NZ196552A (en) * 1980-03-25 1984-07-06 Hoffmann La Roche Cephalosporin derivatives and pharmaceutical compositions;intermediate cephalosporins
GR75706B (cs) * 1980-06-30 1984-08-02 Sanofi Sa
DK379581A (da) * 1980-10-06 1982-04-07 Hoffmann La Roche Fremgangsmaade til fremstilling af acylderivater
FR2494278A1 (fr) * 1980-11-20 1982-05-21 Rhone Poulenc Ind Nouveaux derives de la cephalosporine, leurs preparations et les medicaments qui les contiennent
US4698338A (en) * 1986-02-19 1987-10-06 Eli Lilly And Company 7[2-(2-aminothiazol-4-yl)-2-benzyloximino]acetamido-3[4-alkyl-5-oxo-6-hydroxy-3,4-dihydro-1,2,4-triazin-3-yl]thiomethyl cephalosporins

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1100129A (en) * 1974-08-02 1981-04-28 William H.W. Lunn Cephalosporin compounds
GR63088B (en) * 1976-04-14 1979-08-09 Takeda Chemical Industries Ltd Preparation process of novel cephalosporins
NL7805715A (nl) * 1977-06-03 1978-12-05 Hoffmann La Roche Werkwijze voor het bereiden van acylderivaten.

Also Published As

Publication number Publication date
AT364189B (de) 1981-09-25
GB2010256A (en) 1979-06-27
IT7831016A0 (it) 1978-12-19
FR2412553A1 (fr) 1979-07-20
CH635846A5 (fr) 1983-04-29
ATA908378A (de) 1981-02-15
ZA787110B (en) 1980-08-27
IE782502L (en) 1979-06-20
HU181875B (en) 1983-11-28
MX5586E (es) 1983-10-28
EP0002605A1 (en) 1979-06-27
DK540278A (da) 1979-06-21
DE2861493D1 (en) 1982-02-18
LU80669A1 (fr) 1979-04-13
PH15368A (en) 1982-12-10
IE47696B1 (en) 1984-05-30
RO75804A (ro) 1981-02-28
CA1140112A (en) 1983-01-25
GR72240B (cs) 1983-10-03
IT1112300B (it) 1986-01-13
GB2010256B (en) 1982-09-08
YU300278A (en) 1982-10-31
EG13666A (en) 1983-12-31
AU518484B2 (en) 1981-10-01
EP0002605B1 (en) 1981-12-30
PL123368B1 (en) 1982-10-30
FR2412553B1 (cs) 1982-10-15
PL211973A1 (cs) 1980-03-10
FI67083B (fi) 1984-09-28
NZ189121A (en) 1984-02-03
JPS5490194A (en) 1979-07-17
CS204957B2 (en) 1981-04-30
AU4234778A (en) 1979-06-28
SU793403A3 (ru) 1980-12-30
FI783846A (fi) 1979-06-21
ES476154A1 (es) 1980-05-16
AR220733A1 (es) 1980-11-28
BE872616A (fr) 1979-06-08
US4200745A (en) 1980-04-29
IL56166A0 (en) 1979-03-12
DD139857A5 (de) 1980-01-23
PT68888A (en) 1979-01-01

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Owner name: ELI LILLY AND COMPANY