FI66866C - Foerfarande foer framstaellning av antiproliferativa 2,4-diamino-6-(dialkoxibensyl)pyrido(2,3-d)pyrimidiner - Google Patents

Foerfarande foer framstaellning av antiproliferativa 2,4-diamino-6-(dialkoxibensyl)pyrido(2,3-d)pyrimidiner Download PDF

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Publication number
FI66866C
FI66866C FI801912A FI801912A FI66866C FI 66866 C FI66866 C FI 66866C FI 801912 A FI801912 A FI 801912A FI 801912 A FI801912 A FI 801912A FI 66866 C FI66866 C FI 66866C
Authority
FI
Finland
Prior art keywords
diamino
acid
formula
dimethoxybenzyl
compounds
Prior art date
Application number
FI801912A
Other languages
English (en)
Finnish (fi)
Other versions
FI66866B (fi
FI801912A (fi
Inventor
Eugene Michael Grivsky
David Stanley Duch
Carl William Sigel
Charles Adam Nichol
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of FI801912A publication Critical patent/FI801912A/fi
Publication of FI66866B publication Critical patent/FI66866B/fi
Application granted granted Critical
Publication of FI66866C publication Critical patent/FI66866C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI801912A 1979-06-14 1980-06-13 Foerfarande foer framstaellning av antiproliferativa 2,4-diamino-6-(dialkoxibensyl)pyrido(2,3-d)pyrimidiner FI66866C (fi)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GB7920705 1979-06-14
GB7920706 1979-06-14
GB7920704 1979-06-14
GB7920703 1979-06-14
GB7920705 1979-06-14
GB7920706 1979-06-14
GB7920703 1979-06-14
GB7920704 1979-06-14

Publications (3)

Publication Number Publication Date
FI801912A FI801912A (fi) 1980-12-15
FI66866B FI66866B (fi) 1984-08-31
FI66866C true FI66866C (fi) 1984-12-10

Family

ID=27449125

Family Applications (1)

Application Number Title Priority Date Filing Date
FI801912A FI66866C (fi) 1979-06-14 1980-06-13 Foerfarande foer framstaellning av antiproliferativa 2,4-diamino-6-(dialkoxibensyl)pyrido(2,3-d)pyrimidiner

Country Status (12)

Country Link
EP (1) EP0021292B1 (da)
AU (1) AU532842B2 (da)
CA (1) CA1132137A (da)
DE (1) DE3062268D1 (da)
DK (1) DK157451C (da)
FI (1) FI66866C (da)
HU (1) HU184787B (da)
IE (1) IE49992B1 (da)
IL (1) IL60307A (da)
IT (1) IT1146940B (da)
MY (1) MY8500059A (da)
NZ (1) NZ194045A (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8702758D0 (en) * 1987-02-06 1987-03-11 Wellcome Found Treatment of disease
AU598093B2 (en) * 1987-02-07 1990-06-14 Wellcome Foundation Limited, The Pyridopyrimidines, methods for their preparation and pharmaceutical formulations thereof
US4889859A (en) * 1988-02-05 1989-12-26 The Trustees Of Princeton University Pyrido[2,3-d]pyrimidine derivatives
US5547954A (en) * 1994-05-26 1996-08-20 Fmc Corporation 2,4-Diamino-5,6-disubstituted-and 5,6,7-trisubstituted-5-deazapteridines as insecticides
US6498163B1 (en) 1997-02-05 2002-12-24 Warner-Lambert Company Pyrido[2,3-D]pyrimidines and 4-aminopyrimidines as inhibitors of cellular proliferation
EP0964864B1 (en) * 1997-02-05 2008-04-09 Warner-Lambert Company LLC Pyrido 2,3-d pyrimidines and 4-aminopyrimidines as inhibitors of cellular proliferation
EP1806348A3 (en) * 1997-02-05 2008-01-02 Warner-Lambert Company LLC Pyrido [2, 3 -d] pyrimidines and 4-amino-primidines as inhibitors of cellular proliferation
ES2310039T3 (es) * 1998-05-26 2008-12-16 Warner-Lambert Company Llc Pirimidinas biciclicas y 3,4-dihidropirimidinas biciclicas como inhibidores de la proliferacion celular.
EP1801112A1 (en) * 1998-05-26 2007-06-27 Warner-Lambert Company LLC Bicyclic pyrimidines and bicyclic 3,4-dihydropyrimidines as inhibitors of cellular proliferation
CZ20014181A3 (cs) * 1999-05-24 2002-03-13 Sankyo Company Limited Farmaceutický prostředek obsahující protilátku a pouľití protilátky
GEP20063909B (en) 2002-01-22 2006-08-25 Warner Lambert Co 2-(PYRIDIN-2-YLAMINO)-PYRIDO[2,3d] PYRIMIDIN-7-ONES

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2937284A (en) * 1958-05-01 1960-05-17 Burroughs Wellcome Co 2, 4-diamino-5, 6-dialkylpyrido (2, 3-d) pyrimidines and method
GB970583A (en) * 1961-07-19 1964-09-23 Wellcome Found 2,4-diaminopyrido[2,3-d]pyrimidines
US3322765A (en) * 1963-10-30 1967-05-30 Burroughs Wellcome Co 2, 4-diamino-6-benzylpyrido-(2, 3-d) pyrimidines and method

Also Published As

Publication number Publication date
IT1146940B (it) 1986-11-19
IL60307A0 (en) 1980-09-16
IE49992B1 (en) 1986-01-22
CA1132137A (en) 1982-09-21
DK157451B (da) 1990-01-08
IE801220L (en) 1980-12-14
EP0021292A1 (en) 1981-01-07
AU532842B2 (en) 1983-10-13
AU5927580A (en) 1980-12-18
DK254780A (da) 1980-12-15
HU184787B (en) 1984-10-29
IT8048968A0 (it) 1980-06-13
FI66866B (fi) 1984-08-31
EP0021292B1 (en) 1983-03-09
IL60307A (en) 1984-02-29
FI801912A (fi) 1980-12-15
DK157451C (da) 1990-05-21
NZ194045A (en) 1984-09-28
MY8500059A (en) 1985-12-31
DE3062268D1 (en) 1983-04-14

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Owner name: THE WELLCOME FOUNDATION LIMITED