FI64359C - Analogifoerfarande foer framstaellning av terapeutiskt verksamma 3,4-dihydro-4-oxo-kinazolinderivat - Google Patents
Analogifoerfarande foer framstaellning av terapeutiskt verksamma 3,4-dihydro-4-oxo-kinazolinderivat Download PDFInfo
- Publication number
- FI64359C FI64359C FI763391A FI763391A FI64359C FI 64359 C FI64359 C FI 64359C FI 763391 A FI763391 A FI 763391A FI 763391 A FI763391 A FI 763391A FI 64359 C FI64359 C FI 64359C
- Authority
- FI
- Finland
- Prior art keywords
- dihydro
- carboxy
- oxo
- formula
- phenyl
- Prior art date
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- 230000001225 therapeutic effect Effects 0.000 title claims 3
- 238000012795 verification Methods 0.000 title 1
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- 125000000217 alkyl group Chemical group 0.000 claims description 7
- 229910052757 nitrogen Inorganic materials 0.000 claims description 6
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims description 4
- 125000004399 C1-C4 alkenyl group Chemical group 0.000 claims description 3
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- 125000003373 pyrazinyl group Chemical group 0.000 claims description 3
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- 238000007363 ring formation reaction Methods 0.000 claims description 3
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/93—Sulfur atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT29998/75A IT1050750B (it) | 1975-12-05 | 1975-12-05 | Derivati della 3.4 di idro chinazolina |
| IT2999875 | 1975-12-05 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI763391A7 FI763391A7 (cs) | 1977-06-06 |
| FI64359B FI64359B (fi) | 1983-07-29 |
| FI64359C true FI64359C (fi) | 1983-11-10 |
Family
ID=11228830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI763391A FI64359C (fi) | 1975-12-05 | 1976-11-25 | Analogifoerfarande foer framstaellning av terapeutiskt verksamma 3,4-dihydro-4-oxo-kinazolinderivat |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4251531A (cs) |
| JP (1) | JPS5271485A (cs) |
| AT (1) | AT355029B (cs) |
| AU (1) | AU505660B2 (cs) |
| BE (1) | BE848696A (cs) |
| CA (1) | CA1084051A (cs) |
| CH (2) | CH626073A5 (cs) |
| CS (1) | CS194786B2 (cs) |
| DE (1) | DE2654215A1 (cs) |
| DK (1) | DK147855C (cs) |
| FI (1) | FI64359C (cs) |
| FR (1) | FR2333511A1 (cs) |
| GB (1) | GB1523081A (cs) |
| HU (1) | HU177817B (cs) |
| IL (1) | IL50849A (cs) |
| IT (1) | IT1050750B (cs) |
| NL (1) | NL7613450A (cs) |
| NO (1) | NO146095C (cs) |
| NZ (1) | NZ182778A (cs) |
| SE (1) | SE7613588L (cs) |
| SU (1) | SU786894A3 (cs) |
| ZA (1) | ZA766745B (cs) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4419357A (en) | 1982-01-18 | 1983-12-06 | The Dow Chemical Company | 3-(1H-Tetrazol-5-yl)-4(3H)-quinazolinones |
| IL69274A (en) * | 1982-08-05 | 1986-08-31 | Erba Farmitalia | (substituted amino)derivatives of 3-benzylidene-pyrrolo(2,1-b)quinazolin-9-ones and 6-benzylidene-pyrido(2,1-b)quinazolin-11-ones,their preparation and pharmaceutical compositions containing them |
| US4666913A (en) * | 1985-11-22 | 1987-05-19 | William H. Rorer, Inc. | Hydroxy and aminothiazolyl-benzodiazinone compounds, cardiotonic compositions including the same, and their uses |
| GB8827988D0 (en) * | 1988-11-30 | 1989-01-05 | Smith Kline French Lab | Chemical compounds |
| US5430148A (en) * | 1992-03-31 | 1995-07-04 | Agouron Pharmaceuticals, Inc. | Antiproliferative quinazolines |
| US6632961B1 (en) * | 1998-05-22 | 2003-10-14 | Abbott Laboratories | Antiangiogenic drug to treat cancer, arthritis and retinopathy |
| DE69934113T2 (de) * | 1998-05-22 | 2007-06-06 | Abbott Laboratories, Abbott Park | Antiangiogene substanz zur behandlung von krebs, arthritis und netzhauterkrankungen |
| CO5170498A1 (es) * | 1999-05-28 | 2002-06-27 | Abbott Lab | Biaril sulfonamidas son utiles como inhibidores de proliferacion celular |
| US7893071B2 (en) * | 2001-04-23 | 2011-02-22 | University Of Virginia Patent Foundation | Synthesis and evaluation of novel phthalimide mimics as anti-angiogenic |
| CN100518740C (zh) * | 2003-06-06 | 2009-07-29 | 阿里克斯股份公司 | 杂环化合物作为scce抑制剂的制药用途 |
| EP1631295B1 (en) * | 2003-06-06 | 2010-03-03 | Arexis AB | Use of condensed heterocyclic compounds as scce inhibitors for the treatment of skin diseases |
| CN101501007B (zh) * | 2006-08-08 | 2014-01-29 | Aska制药株式会社 | 喹唑啉衍生物 |
| SI2118074T1 (sl) | 2007-02-01 | 2014-05-30 | Resverlogix Corp. | Spojine za preprečevanje in zdravljenje kardiovaskularnih bolezni |
| CA3146333A1 (en) | 2009-03-18 | 2010-09-23 | Resverlogix Corp. | Phenyl-quinazolin-4(3h)-one and phenyl-pyrido[2,3-d]pyrimidin-4(3h)-one derivatives and compositions thereof useful as anti-inflammatory agents |
| MX352614B (es) | 2009-04-22 | 2017-12-01 | Resverlogix Corp | Nuevos agentes anti-inflamatorios. |
| JP6903585B2 (ja) | 2015-03-13 | 2021-07-14 | レスバーロジックス コーポレイション | 補体関連疾患の治療のための組成物および治療方法 |
| GB201510254D0 (en) * | 2015-06-12 | 2015-07-29 | Syngenta Participations Ag | Improvements in or relating to organic compounds |
| US12012410B2 (en) * | 2018-06-27 | 2024-06-18 | Reborna Biosciences, Inc. | Substituted pyrazolo[1,5-a]pyrazines for spinal muscular atrophy |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3696102A (en) * | 1970-03-09 | 1972-10-03 | Pfizer & Co C | Process for the synthesis of substituted quinazolin-4-ones |
| GB1301319A (cs) | 1970-07-13 | 1972-12-29 |
-
1975
- 1975-12-05 IT IT29998/75A patent/IT1050750B/it active
-
1976
- 1976-11-02 US US05/738,221 patent/US4251531A/en not_active Expired - Lifetime
- 1976-11-04 IL IL50849A patent/IL50849A/xx unknown
- 1976-11-10 ZA ZA766745A patent/ZA766745B/xx unknown
- 1976-11-10 AU AU19472/76A patent/AU505660B2/en not_active Expired
- 1976-11-24 BE BE172653A patent/BE848696A/xx not_active IP Right Cessation
- 1976-11-25 FI FI763391A patent/FI64359C/fi not_active IP Right Cessation
- 1976-11-30 DE DE19762654215 patent/DE2654215A1/de not_active Withdrawn
- 1976-12-01 GB GB50164/76A patent/GB1523081A/en not_active Expired
- 1976-12-01 NZ NZ182778A patent/NZ182778A/xx unknown
- 1976-12-02 NL NL7613450A patent/NL7613450A/xx not_active Application Discontinuation
- 1976-12-02 AT AT894376A patent/AT355029B/de not_active IP Right Cessation
- 1976-12-02 FR FR7636343A patent/FR2333511A1/fr active Granted
- 1976-12-03 SE SE7613588A patent/SE7613588L/xx not_active Application Discontinuation
- 1976-12-03 DK DK546776A patent/DK147855C/da not_active IP Right Cessation
- 1976-12-03 HU HU76EA167A patent/HU177817B/hu unknown
- 1976-12-03 CS CS767886A patent/CS194786B2/cs unknown
- 1976-12-03 SU SU762426155A patent/SU786894A3/ru active
- 1976-12-03 NO NO764135A patent/NO146095C/no unknown
- 1976-12-03 CA CA267,090A patent/CA1084051A/en not_active Expired
- 1976-12-03 CH CH1527276A patent/CH626073A5/de not_active IP Right Cessation
- 1976-12-06 JP JP51146444A patent/JPS5271485A/ja active Granted
-
1980
- 1980-11-28 CH CH885580A patent/CH626075A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI763391A7 (cs) | 1977-06-06 |
| DK147855B (da) | 1984-12-24 |
| BE848696A (fr) | 1977-03-16 |
| CH626073A5 (cs) | 1981-10-30 |
| HU177817B (en) | 1981-12-28 |
| NL7613450A (nl) | 1977-06-07 |
| IT1050750B (it) | 1981-03-20 |
| SE7613588L (sv) | 1977-06-06 |
| FR2333511A1 (fr) | 1977-07-01 |
| CH626075A5 (cs) | 1981-10-30 |
| US4251531A (en) | 1981-02-17 |
| NO146095C (no) | 1982-08-11 |
| JPS5543464B2 (cs) | 1980-11-06 |
| NZ182778A (en) | 1978-07-28 |
| IL50849A0 (en) | 1977-01-31 |
| AU1947276A (en) | 1978-05-18 |
| ZA766745B (en) | 1977-10-26 |
| SU786894A3 (ru) | 1980-12-07 |
| DE2654215A1 (de) | 1977-06-16 |
| ATA894376A (de) | 1979-07-15 |
| CS194786B2 (en) | 1979-12-31 |
| AU505660B2 (en) | 1979-11-29 |
| JPS5271485A (en) | 1977-06-14 |
| CA1084051A (en) | 1980-08-19 |
| DK546776A (da) | 1977-06-06 |
| FI64359B (fi) | 1983-07-29 |
| AT355029B (de) | 1980-02-11 |
| GB1523081A (en) | 1978-08-31 |
| NO764135L (cs) | 1977-06-07 |
| FR2333511B1 (cs) | 1979-03-02 |
| DK147855C (da) | 1985-06-10 |
| IL50849A (en) | 1980-11-30 |
| NO146095B (no) | 1982-04-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: FARMITALIA CARLO ERBA S.P.A |