FI63671C - Foerfarande foer bildande av en doseringsenhetsform av en hjaertmedicin - Google Patents
Foerfarande foer bildande av en doseringsenhetsform av en hjaertmedicin Download PDFInfo
- Publication number
- FI63671C FI63671C FI750964A FI750964A FI63671C FI 63671 C FI63671 C FI 63671C FI 750964 A FI750964 A FI 750964A FI 750964 A FI750964 A FI 750964A FI 63671 C FI63671 C FI 63671C
- Authority
- FI
- Finland
- Prior art keywords
- digoxin
- hjaertmedicin
- doseringsenhetsform
- weight
- foerfarande foer
- Prior art date
Links
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 18
- LTMHDMANZUZIPE-AMTYYWEZSA-N Digoxin Natural products O([C@H]1[C@H](C)O[C@H](O[C@@H]2C[C@@H]3[C@@](C)([C@@H]4[C@H]([C@]5(O)[C@](C)([C@H](O)C4)[C@H](C4=CC(=O)OC4)CC5)CC3)CC2)C[C@@H]1O)[C@H]1O[C@H](C)[C@@H](O[C@H]2O[C@@H](C)[C@H](O)[C@@H](O)C2)[C@@H](O)C1 LTMHDMANZUZIPE-AMTYYWEZSA-N 0.000 description 14
- LTMHDMANZUZIPE-PUGKRICDSA-N digoxin Chemical compound C1[C@H](O)[C@H](O)[C@@H](C)O[C@H]1O[C@@H]1[C@@H](C)O[C@@H](O[C@@H]2[C@H](O[C@@H](O[C@@H]3C[C@@H]4[C@]([C@@H]5[C@H]([C@]6(CC[C@@H]([C@@]6(C)[C@H](O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)C[C@@H]2O)C)C[C@@H]1O LTMHDMANZUZIPE-PUGKRICDSA-N 0.000 description 14
- 229960005156 digoxin Drugs 0.000 description 14
- LTMHDMANZUZIPE-UHFFFAOYSA-N digoxine Natural products C1C(O)C(O)C(C)OC1OC1C(C)OC(OC2C(OC(OC3CC4C(C5C(C6(CCC(C6(C)C(O)C5)C=5COC(=O)C=5)O)CC4)(C)CC3)CC2O)C)CC1O LTMHDMANZUZIPE-UHFFFAOYSA-N 0.000 description 14
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 12
- 239000002775 capsule Substances 0.000 description 10
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 9
- 239000004480 active ingredient Substances 0.000 description 9
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 description 7
- 229920001223 polyethylene glycol Polymers 0.000 description 7
- 239000003826 tablet Substances 0.000 description 7
- 239000002202 Polyethylene glycol Substances 0.000 description 6
- 239000007903 gelatin capsule Substances 0.000 description 5
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 4
- 239000002371 cardiac agent Substances 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 239000000600 sorbitol Substances 0.000 description 4
- 108010010803 Gelatin Proteins 0.000 description 3
- 229920002565 Polyethylene Glycol 400 Polymers 0.000 description 3
- MTHSVFCYNBDYFN-UHFFFAOYSA-N diethylene glycol Chemical compound OCCOCCO MTHSVFCYNBDYFN-UHFFFAOYSA-N 0.000 description 3
- 239000008273 gelatin Substances 0.000 description 3
- 229920000159 gelatin Polymers 0.000 description 3
- 235000019322 gelatine Nutrition 0.000 description 3
- 235000011852 gelatine desserts Nutrition 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000004014 plasticizer Substances 0.000 description 3
- 230000000747 cardiac effect Effects 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000007791 liquid phase Substances 0.000 description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- 239000002368 cardiac glycoside Substances 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 229930182478 glucoside Natural products 0.000 description 1
- 150000008131 glucosides Chemical class 0.000 description 1
- TZMQHOJDDMFGQX-UHFFFAOYSA-N hexane-1,1,1-triol Chemical compound CCCCCC(O)(O)O TZMQHOJDDMFGQX-UHFFFAOYSA-N 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000007935 oral tablet Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1426574 | 1974-04-01 | ||
| GB14265/74A GB1508770A (en) | 1974-04-01 | 1974-04-01 | Pharmaceutical compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI750964A7 FI750964A7 (en, 2012) | 1975-10-02 |
| FI63671B FI63671B (fi) | 1983-04-29 |
| FI63671C true FI63671C (fi) | 1983-08-10 |
Family
ID=10038031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI750964A FI63671C (fi) | 1974-04-01 | 1975-04-01 | Foerfarande foer bildande av en doseringsenhetsform av en hjaertmedicin |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPS5644045B2 (en, 2012) |
| AT (1) | AT342777B (en, 2012) |
| AU (1) | AU500001B2 (en, 2012) |
| BE (1) | BE827349A (en, 2012) |
| CA (1) | CA1046410A (en, 2012) |
| DE (1) | DE2513601A1 (en, 2012) |
| DK (1) | DK137436B (en, 2012) |
| FI (1) | FI63671C (en, 2012) |
| FR (1) | FR2265353B1 (en, 2012) |
| GB (1) | GB1508770A (en, 2012) |
| NL (1) | NL7503881A (en, 2012) |
| SE (1) | SE408687B (en, 2012) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2805165A1 (de) * | 1977-02-09 | 1978-08-10 | Christiaens Sa A | Gitoxin enthaltendes arzneimittel und verfahren zu seiner herstellung |
| EP0649651B1 (en) | 1993-09-28 | 2000-12-13 | R.P. Scherer GmbH | Soft gelatin capsule manufacture |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1481411A (en) * | 1973-07-20 | 1977-07-27 | Scherer Ltd R | Pharmaceutical compositions |
| IL46682A (en) * | 1974-02-22 | 1979-07-25 | Wellcome Found | Pharmaceutical capsules containing difoxin |
-
1974
- 1974-04-01 GB GB14265/74A patent/GB1508770A/en not_active Expired
-
1975
- 1975-03-27 SE SE7503592A patent/SE408687B/xx not_active IP Right Cessation
- 1975-03-27 DE DE19752513601 patent/DE2513601A1/de active Granted
- 1975-03-28 BE BE154915A patent/BE827349A/xx not_active IP Right Cessation
- 1975-04-01 FI FI750964A patent/FI63671C/fi not_active IP Right Cessation
- 1975-04-01 FR FR7510180A patent/FR2265353B1/fr not_active Expired
- 1975-04-01 DK DK138675AA patent/DK137436B/da not_active IP Right Cessation
- 1975-04-01 AU AU79663/75A patent/AU500001B2/en not_active Expired
- 1975-04-01 CA CA223,484A patent/CA1046410A/en not_active Expired
- 1975-04-01 NL NL7503881A patent/NL7503881A/xx not_active Application Discontinuation
- 1975-04-01 AT AT244575A patent/AT342777B/de not_active IP Right Cessation
- 1975-04-01 JP JP3968275A patent/JPS5644045B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS517117A (en, 2012) | 1976-01-21 |
| FI750964A7 (en, 2012) | 1975-10-02 |
| NL7503881A (nl) | 1975-10-03 |
| SE7503592L (en, 2012) | 1975-10-02 |
| ATA244575A (de) | 1977-08-15 |
| DE2513601C2 (en, 2012) | 1988-05-26 |
| AT342777B (de) | 1978-04-25 |
| FR2265353B1 (en, 2012) | 1980-02-15 |
| BE827349A (fr) | 1975-09-29 |
| DK138675A (en, 2012) | 1975-10-02 |
| GB1508770A (en) | 1978-04-26 |
| AU7966375A (en) | 1976-10-07 |
| SE408687B (sv) | 1979-07-02 |
| CA1046410A (en) | 1979-01-16 |
| JPS5644045B2 (en, 2012) | 1981-10-16 |
| FR2265353A1 (en, 2012) | 1975-10-24 |
| DE2513601A1 (de) | 1975-10-02 |
| AU500001B2 (en) | 1979-05-10 |
| DK137436B (da) | 1978-03-06 |
| DK137436C (en, 2012) | 1978-08-21 |
| FI63671B (fi) | 1983-04-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US3131123A (en) | Enteric tablets and manufacture thereof | |
| RU2121344C1 (ru) | Лекарственная форма двухфазного действия с высвобождением для липофильных лекарственных препаратов и способ ее получения | |
| Nau et al. | A new model for embryotoxicity testing: teratogenicity and pharmacokinetics of valproic acid following constant-rate administration in the mouse using human therapeutic drug and metabolite concentrations | |
| US3344029A (en) | Sustained release composition | |
| KR850000975A (ko) | 발프로익산과 그 염의 혼합물을 토대로 한 조성물 | |
| US2736682A (en) | Method of making a prolonged action medicinal tablet | |
| KR840000228A (ko) | 조제성 혼합물에 있어서 건성분말의 제조방법 | |
| DE19648576A1 (de) | Lutschtablette zur modifizierten Freisetzung von Wirkstoffen im Gastrointestinaltrakt | |
| KR830005854A (ko) | 알카리성 진통제 캡슐의 제조방법 | |
| Chung et al. | Comparative pharmacokinetics of Theracurmin, a highly bioavailable curcumin, in healthy adult subjects | |
| JPS61501202A (ja) | アセトアミノフェン・ゼラチンカプセル | |
| US4067960A (en) | Pharmaceutical compositions containing cardiac glycoside | |
| EP0025686B1 (en) | Pharmaceutical composition containing paracetamol, treatment pack comprising said composition and method of reducing liver toxicity effect of paracetamol compositions | |
| Usmanova et al. | AN UNDERSTANDING OF THE FORMULATION OF THE DRUG AND THE RELEASE OF THE ACTIVE SUBSTANCES OF THE DRUG | |
| FI63670B (fi) | Foerfarande foer framstaellning av digoxin innehaollande doseringsenheter | |
| FI63671B (fi) | Foerfarande foer bildande av en doseringsenhetsform av en hjaertmedicin | |
| JP2004210780A (ja) | 甲状腺ホルモン用医薬形態およびそれを得るための方法 | |
| CN109833309A (zh) | 美金刚缓释微片胶囊及其制备方法 | |
| AU2024208438A1 (en) | Self-emulsifying pharmaceutical composition, preparation method therefor, and application thereof | |
| EP0414688B1 (en) | Process for regulating the absorption rate of drugs and a pharmaceutical formulation | |
| Woo et al. | Liquid-filled hard capsule formulation of choline alfoscerate: preparation and in vitro/in vivo evaluation | |
| CN114073683A (zh) | 一种维生素口溶膜剂及其制备方法 | |
| US4305935A (en) | Bone formation stimulant | |
| US2870060A (en) | Stable encapsulated solution of a salt of a dialkyl sulfosuccinate | |
| WO2021212865A1 (zh) | 一种复方大蒜素软胶囊及其制备包装方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: R.P. SCHERER LIMITED |