FI63226C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 1-difenylmetyl-3-metyl-3-bensylpiperazinderivat - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 1-difenylmetyl-3-metyl-3-bensylpiperazinderivat Download PDF

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Publication number
FI63226C
FI63226C FI770398A FI770398A FI63226C FI 63226 C FI63226 C FI 63226C FI 770398 A FI770398 A FI 770398A FI 770398 A FI770398 A FI 770398A FI 63226 C FI63226 C FI 63226C
Authority
FI
Finland
Prior art keywords
methyl
methanol
diphenylmethyl
dimethoxybenzyl
piperazine
Prior art date
Application number
FI770398A
Other languages
English (en)
Finnish (fi)
Other versions
FI770398A (sv
FI63226B (fi
Inventor
Richard Cyrus
Manfred Raschack
Original Assignee
Knoll Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag filed Critical Knoll Ag
Publication of FI770398A publication Critical patent/FI770398A/fi
Publication of FI63226B publication Critical patent/FI63226B/fi
Application granted granted Critical
Publication of FI63226C publication Critical patent/FI63226C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
FI770398A 1976-02-07 1977-02-07 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 1-difenylmetyl-3-metyl-3-bensylpiperazinderivat FI63226C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19762604845 DE2604845A1 (de) 1976-02-07 1976-02-07 Neue piperazinderivate
DE2604845 1976-02-07

Publications (3)

Publication Number Publication Date
FI770398A FI770398A (sv) 1977-08-08
FI63226B FI63226B (fi) 1983-01-31
FI63226C true FI63226C (fi) 1983-05-10

Family

ID=5969327

Family Applications (1)

Application Number Title Priority Date Filing Date
FI770398A FI63226C (fi) 1976-02-07 1977-02-07 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 1-difenylmetyl-3-metyl-3-bensylpiperazinderivat

Country Status (25)

Country Link
US (1) US4079137A (sv)
JP (1) JPS52105186A (sv)
AT (1) AT355578B (sv)
AU (1) AU504526B2 (sv)
BE (1) BE850492A (sv)
CA (1) CA1094560A (sv)
CH (1) CH631448A5 (sv)
CS (1) CS201544B2 (sv)
DD (1) DD128133A5 (sv)
DE (1) DE2604845A1 (sv)
DK (1) DK138891C (sv)
ES (1) ES455691A1 (sv)
FI (1) FI63226C (sv)
FR (1) FR2340311A1 (sv)
GB (1) GB1550545A (sv)
HU (1) HU173483B (sv)
IE (1) IE44339B1 (sv)
IL (1) IL51316A (sv)
LU (1) LU76706A1 (sv)
NL (1) NL7700841A (sv)
NO (1) NO142625C (sv)
PL (1) PL105526B1 (sv)
PT (1) PT66154B (sv)
SE (1) SE7701187L (sv)
ZA (1) ZA77248B (sv)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341698A (en) * 1979-06-21 1982-07-27 Richardson-Merrell Inc. Enkaphalin derivatives
US4483988A (en) * 1980-03-14 1984-11-20 Richardson Merrell Inc. Substituted derivatives of 4-t-alkoxycarbonyl-piperazin-2-ones
US4766125A (en) * 1981-06-23 1988-08-23 Janssen Pharmaceutica N.V. N-aryl-piperazinealkanamides useful for protecting hearts from myocardial injury caused by ischaemia, anoxia or hypoxia
AU2005314271B2 (en) 2004-12-06 2011-06-16 Sciclone Pharmaceuticals, Inc. Alpha thymosin peptides as cancer vaccine adjuvants
US20080300166A1 (en) * 2007-06-01 2008-12-04 Sciclone Pharmaceuticals, Inc. Treatment of Melanoma with Alpha Thymosin Peptides
EP2240195A4 (en) * 2007-12-12 2011-12-21 Sciclone Pharmaceuticals Inc TREATMENT OF MELANOMA WITH ALPHA-THYMOSIN PEPTIDES IN ASSOCIATION WITH ANTIBODIES AGAINST ANTIGEN 4 ASSOCIATED WITH CYTOTOXIC LYMPHOCYTE T (CTLA4)
CA2708229A1 (en) * 2007-12-13 2009-06-18 Sciclone Pharmaceuticals, Inc. Treatment of melanoma with alpha thymosin peptides in combination with a kinase inhibitor
EP2230908A1 (en) * 2007-12-14 2010-09-29 Sciclone Pharmaceuticals, Inc. Treatment of melanoma with alpha thymosin peptides in combination with an antineoplastic heat shock apoptosis activator (hsaa)
US8829173B2 (en) 2008-09-26 2014-09-09 Tocagen Inc. Recombinant vectors
WO2010129947A2 (en) * 2009-05-08 2010-11-11 Sciclone Pharmaceuticals, Inc. Alpha thymosin peptides as vaccine enhancers
CN113855806A (zh) 2014-10-21 2021-12-31 赛生药品股份国际有限公司 用免疫刺激剂治疗癌症

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3472856A (en) * 1967-05-29 1969-10-14 Sterling Drug Inc 1-((thianaphthenyl)-lower-alkyl)-4-substituted-piperazines
US4031216A (en) * 1974-08-12 1977-06-21 Knoll A.G. Chemische Fabriken 3-(3,4-Dialkoxy-benzyl)-3-methyl-piperazines
DE2438725A1 (de) * 1974-08-12 1976-02-26 Knoll Ag Piperazinderivate

Also Published As

Publication number Publication date
CH631448A5 (de) 1982-08-13
DK138891C (da) 1979-04-23
DK138891B (da) 1978-11-13
IL51316A0 (en) 1977-03-31
DK49077A (da) 1977-08-08
DE2604845A1 (de) 1977-08-18
PL105526B1 (pl) 1979-10-31
BE850492A (fr) 1977-07-18
AU2195277A (en) 1978-08-10
IE44339B1 (en) 1981-10-21
PT66154B (fr) 1978-07-07
SE7701187L (sv) 1977-08-08
FI770398A (sv) 1977-08-08
ES455691A1 (es) 1978-01-01
NO142625B (no) 1980-06-09
LU76706A1 (sv) 1977-06-28
IE44339L (en) 1977-08-07
FR2340311B1 (sv) 1980-02-08
AU504526B2 (en) 1979-10-18
CS201544B2 (en) 1980-11-28
GB1550545A (en) 1979-08-15
HU173483B (hu) 1979-05-28
JPS52105186A (en) 1977-09-03
US4079137A (en) 1978-03-14
FI63226B (fi) 1983-01-31
CA1094560A (en) 1981-01-27
NO770374L (no) 1977-08-09
ZA77248B (en) 1977-11-30
FR2340311A1 (fr) 1977-09-02
DD128133A5 (de) 1977-11-02
PT66154A (fr) 1977-03-01
ATA68177A (de) 1979-08-15
IL51316A (en) 1980-12-31
AT355578B (de) 1980-03-10
NL7700841A (nl) 1977-08-09
NO142625C (no) 1980-09-17

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Owner name: KNOLL AG