FI61183C - Foerfarande foer framstaellning av terapeutiskt anvaendbara n-fenylpyrroler - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara n-fenylpyrroler Download PDF

Info

Publication number
FI61183C
FI61183C FI580/74A FI58074A FI61183C FI 61183 C FI61183 C FI 61183C FI 580/74 A FI580/74 A FI 580/74A FI 58074 A FI58074 A FI 58074A FI 61183 C FI61183 C FI 61183C
Authority
FI
Finland
Prior art keywords
mol
hours
moles
carboxy
phenyl
Prior art date
Application number
FI580/74A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI61183B (fi
Inventor
Richard C Allen
V Brian Anderson
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Application granted granted Critical
Publication of FI61183B publication Critical patent/FI61183B/fi
Publication of FI61183C publication Critical patent/FI61183C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/70[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/562Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/60Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Fodder In General (AREA)
  • Pyridine Compounds (AREA)
FI580/74A 1973-03-01 1974-02-27 Foerfarande foer framstaellning av terapeutiskt anvaendbara n-fenylpyrroler FI61183C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33691973 1973-03-01
US336919A US3878225A (en) 1973-03-01 1973-03-01 Condensed pyrroles bearing an N-phenyl substituent

Publications (2)

Publication Number Publication Date
FI61183B FI61183B (fi) 1982-02-26
FI61183C true FI61183C (fi) 1982-06-10

Family

ID=23318274

Family Applications (1)

Application Number Title Priority Date Filing Date
FI580/74A FI61183C (fi) 1973-03-01 1974-02-27 Foerfarande foer framstaellning av terapeutiskt anvaendbara n-fenylpyrroler

Country Status (20)

Country Link
US (1) US3878225A (es)
JP (1) JPS6139304B2 (es)
AT (1) AT332389B (es)
BE (1) BE811785A (es)
CA (1) CA1025455A (es)
CH (1) CH611605A5 (es)
CS (1) CS191225B2 (es)
DE (1) DE2407671C2 (es)
ES (2) ES423562A1 (es)
FI (1) FI61183C (es)
FR (1) FR2219790B1 (es)
GB (1) GB1457601A (es)
HU (1) HU170834B (es)
IE (1) IE38943B1 (es)
IL (1) IL44279A (es)
NL (1) NL177828C (es)
NO (1) NO142346C (es)
SE (1) SE397523B (es)
SU (1) SU610488A3 (es)
ZA (1) ZA741333B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4056624A (en) * 1976-05-14 1977-11-01 American Hoechst Corporation Method of treating dermal inflammation
US4929622A (en) * 1987-09-24 1990-05-29 Hoechst-Roussel Pharmaceuticals, Inc. 2,6-Methanopyrrolo-3-benzazocines
US5145965A (en) * 1987-09-24 1992-09-08 Hoechst-Roussel Pharmaceuticals Incorporated 2,6-methanopyrrolo-3-benzazocines
US4814501A (en) * 1987-12-28 1989-03-21 Merck & Co., Inc. Process for preparing N,N-dimethyl 2-(methylthio) benzamides and analogs
CA2582674A1 (en) * 2004-10-04 2006-04-20 Myriad Genetics, Inc. Compounds for alzheimer's disease
US9216966B2 (en) 2004-10-04 2015-12-22 John Manfredi Compounds for Alzheimer's disease
US7678823B2 (en) * 2004-10-04 2010-03-16 Myriad Pharmaceticals, Inc. Compounds for alzheimer's disease
AU2007234399A1 (en) * 2006-04-04 2007-10-11 Myriad Genetics, Inc. Compounds for diseases and disorders
MX2010000918A (es) * 2007-07-24 2010-03-15 Astellas Pharma Inc Derivado de bencimidazol.
US8367665B2 (en) * 2008-04-16 2013-02-05 Karo Bio Ab Estrogen receptor ligands
GB201113538D0 (en) 2011-08-04 2011-09-21 Karobio Ab Novel estrogen receptor ligands

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD70880A (es) *
US3687971A (en) * 1970-06-22 1972-08-29 Merck & Co Inc 4-(pyrrolyl)-salicylic acid derivatives
GB1351754A (en) * 1970-07-02 1974-05-01 Allen & Hanburys Ltd Indenopyrrole derivatives

Also Published As

Publication number Publication date
JPS6139304B2 (es) 1986-09-03
NL177828C (nl) 1985-12-02
ES437259A1 (es) 1977-01-01
AT332389B (de) 1976-09-27
GB1457601A (en) 1976-12-08
ATA165474A (de) 1976-01-15
IE38943L (en) 1974-09-01
DE2407671A1 (de) 1974-09-12
NO142346B (no) 1980-04-28
IE38943B1 (en) 1978-07-05
JPS49134671A (es) 1974-12-25
IL44279A (en) 1977-10-31
SU610488A3 (ru) 1978-06-05
HU170834B (hu) 1977-09-28
BE811785A (fr) 1974-09-02
CA1025455A (en) 1978-01-31
DE2407671C2 (de) 1983-12-01
NO142346C (no) 1980-08-06
FR2219790A1 (es) 1974-09-27
CS191225B2 (en) 1979-06-29
CH611605A5 (es) 1979-06-15
NO740694L (no) 1974-09-03
NL177828B (nl) 1985-07-01
FI61183B (fi) 1982-02-26
ZA741333B (en) 1975-02-26
AU6618874A (en) 1975-09-04
FR2219790B1 (es) 1978-09-22
NL7402465A (es) 1974-09-03
ES423562A1 (es) 1976-06-01
US3878225A (en) 1975-04-15
SE397523B (sv) 1977-11-07
IL44279A0 (en) 1974-05-16

Similar Documents

Publication Publication Date Title
US4233299A (en) 4-Hydroxy-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxides and salts thereof
US4585771A (en) Antiinflammatory imidazole derivatives
FI61183C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara n-fenylpyrroler
JP2539504B2 (ja) ヒドロキシスチレン誘導体
JPH02270874A (ja) アザビシクロ化合物及びそれらの塩、それらの製造方法、それらを含有する製薬組成物並びにそれらの薬剤としての使用
Toja et al. 3-Alkyl-2-aryl-3H-naphth [1, 2-d] imidazoles, a novel class of nonacidic antiinflammatory agents
CZ274996A3 (en) Heterocyclic aromatic oxazole compounds, their oxime, ketone, ketonemethylene, ester and amide compounds, pharmaceutical preparations, cyclooxygenase inhibitors and antiphlogistic agents in which said oxazole compounds are comprised
JPS6322080A (ja) 薬理学的に活性な1,5−ジアリ−ル−3−置換−ピラゾ−ル類およびそれらを製造する方法
CA1144550A (en) Antiinflammatory 4,5-diaryl-2-(substituted-thio) pyrroles and their corresponding sulfoxides and sulfones
EP0611766A1 (fr) Dérivés de 2-amido-thiazoles polysubstitués, procédé de préparation, composition pharmaceutique et utilisation de ces dérivés pour la préparation d'un médicament
US3975531A (en) 4-(5- And 7-)benzoylindolin-2-ones and pharmaceutical uses thereof
US4678802A (en) 1-acylcarbamoyloxindole-3-carboxamides as antiinflammatory agents
US5110831A (en) Vinylogous hydroxamic acids and derivatives thereof as 5-lipoxygenase inhibitors
JPH039114B2 (es)
PL141609B1 (en) Process for preparing novel derivatives of 2/1h,3h/indolones
US3931407A (en) Method of treatment with and compositions containing condensed pyrroles bearing an N-phenyl substituent
HU177338B (en) Process for producing acylamino-heteroaryl compounds
US4267190A (en) Antiinflammatory 4,5-diaryl-α,α-bis(polyfluoromethyl)-1H-pyrrole-2-methanethiols
US4335136A (en) Anti-inflammatory 4,5-diaryl-α-(polyfluoroalkyl)-1H-pyrrole-2-methanamines
US4160032A (en) Oxindoles as sleep-inducers
HU196749B (en) Process for producing 2-pyrrolidone derivatives and pharmaceutical compositions comprising such compounds as active ingredient
US4273773A (en) Antihypertensive tricyclic isoindole derivatives
US4347251A (en) Novel 3-substituted amino-1-substituted heteroaryl-2-pyrazolines
US4173577A (en) Phenylacetohydroxamic acids
HUT59096A (en) Process for producing indenoindol compounds and pharmaceutical compositions containing them