FI61030C - Foerfarande foer framstaellning av terapeutiskt verkande 2-substituerade-1- eller 3-benzoyl-indolizinderivat - Google Patents

Foerfarande foer framstaellning av terapeutiskt verkande 2-substituerade-1- eller 3-benzoyl-indolizinderivat Download PDF

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Publication number
FI61030C
FI61030C FI770318A FI770318A FI61030C FI 61030 C FI61030 C FI 61030C FI 770318 A FI770318 A FI 770318A FI 770318 A FI770318 A FI 770318A FI 61030 C FI61030 C FI 61030C
Authority
FI
Finland
Prior art keywords
benzoyl
indolizine
formula
phenyl
ethyl
Prior art date
Application number
FI770318A
Other languages
English (en)
Finnish (fi)
Other versions
FI770318A (de
FI61030B (fi
Inventor
Jean Gubin
Gilbert Rosseels
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB6680/76A external-priority patent/GB1518443A/en
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of FI770318A publication Critical patent/FI770318A/fi
Publication of FI61030B publication Critical patent/FI61030B/fi
Application granted granted Critical
Publication of FI61030C publication Critical patent/FI61030C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
    • C07D213/20—Quaternary compounds thereof

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
FI770318A 1976-02-19 1977-01-31 Foerfarande foer framstaellning av terapeutiskt verkande 2-substituerade-1- eller 3-benzoyl-indolizinderivat FI61030C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB668076 1976-02-19
GB6680/76A GB1518443A (en) 1976-02-19 1976-02-19 Indolizine derivatives and process for preparing the same
GB3331476 1976-08-10
GB3331476 1976-08-10

Publications (3)

Publication Number Publication Date
FI770318A FI770318A (de) 1977-08-20
FI61030B FI61030B (fi) 1982-01-29
FI61030C true FI61030C (fi) 1982-05-10

Family

ID=26240878

Family Applications (1)

Application Number Title Priority Date Filing Date
FI770318A FI61030C (fi) 1976-02-19 1977-01-31 Foerfarande foer framstaellning av terapeutiskt verkande 2-substituerade-1- eller 3-benzoyl-indolizinderivat

Country Status (22)

Country Link
US (1) US4103012A (de)
JP (1) JPS52125193A (de)
AR (2) AR211887A1 (de)
AT (1) AT358035B (de)
AU (1) AU505894B2 (de)
CA (1) CA1071198A (de)
CH (2) CH617697A5 (de)
DE (1) DE2707048C2 (de)
DK (1) DK142622B (de)
ES (2) ES456039A1 (de)
FI (1) FI61030C (de)
FR (1) FR2341578A1 (de)
GR (1) GR59328B (de)
IE (1) IE44941B1 (de)
IT (1) IT1085862B (de)
NL (1) NL164283C (de)
NO (1) NO145842C (de)
NZ (1) NZ183377A (de)
OA (1) OA05575A (de)
PT (1) PT66199B (de)
SE (1) SE420314B (de)
YU (3) YU39489B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ193926A (en) * 1979-07-06 1984-05-31 Labaz Sanofi Nv 2-(alkyl or phenyl)-3(4-hydroxybenzoyl)indolizines
US4378362A (en) * 1979-12-06 1983-03-29 S.A. Labaz N.V. Indolizine derivatives and process for preparing the same
FR2495616A1 (fr) * 1980-12-09 1982-06-11 Labaz Nv Nouveaux derives d'indolizine, leur procede de preparation ainsi que leurs applications en therapeutique
US4520026A (en) * 1981-02-06 1985-05-28 S. A. Labaz N.V. Indolizine derivatives and use as cardiovascular agents
FR2528845A1 (fr) * 1982-06-17 1983-12-23 Sanofi Sa Nouveaux derives d'indolizine, leur procede de preparation ainsi que les compositions therapeutiques les contenant
JPS59113802U (ja) * 1983-01-14 1984-08-01 オムロン株式会社 制御装置
US5215988A (en) * 1986-02-14 1993-06-01 Sanofi Aminoalkoxyphenyl derivatives, process of preparation and compositions containing the same
FR2594438B1 (fr) * 1986-02-14 1990-01-26 Labaz Sanofi Nv Derives d'indolizine, leur procede de preparation ainsi que les compositions en contenant
NZ221717A (en) * 1986-09-10 1990-08-28 Sandoz Ltd Azaindole and indolizine derivatives and pharmaceutical compositions
IL87181A (en) * 1987-08-07 1993-08-18 Sanofi Sa Aminoalkoxyphenyl derivatives, their preparation and pharmaceutical and veterinary compositions containing them
US4880824A (en) * 1987-09-21 1989-11-14 Ortho Pharmaceutical Corporation Phenyl and benzoyl substituted imidazo-fused heterocyclic calcium channel blockers
FR2642756B1 (fr) * 1989-02-07 1994-03-04 Sanofi Derives cycloaminoalkoxyphenyle, leur procede de preparation ainsi que les compositions pharmaceutiques ou veterinaires en contenant
FR2642755B1 (de) * 1989-02-07 1993-11-05 Sanofi
FR2665444B1 (fr) * 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
FR2893616B1 (fr) * 2005-11-23 2008-01-04 Sanofi Aventis Sa Nouveaux derives d'indolizine, leur procede de preparation et les compositions therapeutiques les comprenant
FR2967412B1 (fr) 2010-11-17 2012-12-14 Sanofi Aventis Nouveaux derives d'indolizine, leur preparation et leur application en therapeutique
CN110283167A (zh) * 2018-11-14 2019-09-27 贵州省中国科学院天然产物化学重点实验室 一种抗心率失常药物布托普洛嗪的制备方法

Also Published As

Publication number Publication date
FR2341578B1 (de) 1980-04-30
FI770318A (de) 1977-08-20
ATA92077A (de) 1980-01-15
AU505894B2 (en) 1979-12-06
AR211887A1 (es) 1978-03-31
NL164283B (nl) 1980-07-15
DK142622B (da) 1980-12-01
IE44941L (en) 1977-08-19
IT1085862B (it) 1985-05-28
DE2707048A1 (de) 1977-09-01
AU2239477A (en) 1978-08-24
NO145842C (no) 1982-06-09
DK72677A (de) 1977-08-20
YU42877A (en) 1983-01-21
IE44941B1 (en) 1982-05-19
ES467441A1 (es) 1978-10-16
YU39489B (en) 1984-12-31
OA05575A (fr) 1981-04-30
YU42791B (en) 1988-12-31
YU225183A (en) 1984-10-31
YU42888B (en) 1988-12-31
CH617697A5 (de) 1980-06-13
AT358035B (de) 1980-08-11
NO145842B (no) 1982-03-01
FI61030B (fi) 1982-01-29
PT66199B (pt) 1978-07-12
SE420314B (sv) 1981-09-28
FR2341578A1 (fr) 1977-09-16
CA1071198A (en) 1980-02-05
SE7701771L (sv) 1977-08-20
JPS5519234B2 (de) 1980-05-24
CH623322A5 (de) 1981-05-29
PT66199A (pt) 1977-03-01
NL7701678A (nl) 1977-08-23
GR59328B (en) 1977-12-13
NO770547L (no) 1977-08-22
DE2707048C2 (de) 1983-11-17
NL164283C (nl) 1980-12-15
JPS52125193A (en) 1977-10-20
NZ183377A (en) 1980-04-28
ES456039A1 (es) 1978-05-16
DK142622C (de) 1981-08-03
AR212791A1 (es) 1978-09-29
US4103012A (en) 1978-07-25

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MM Patent lapsed

Owner name: SANOFI